Abstract: The invention relates to derivatives of tropoelastin and variants of those derivatives. The invention further provides expression products and hybrid molecules of the derivatives and variants of the invention. The invention further provides methods for the production of the derivatives, variants, expression products and hybrid molecules. Further provided are formulations, cross-linked structures and implants comprising the derivatives, variants, expression products and hybrid molecules of the invention. Further provided are uses of the derivatives, variants, expression products and hybrid molecules of the invention.

Abstract: Disclosed are an inverter, a NAND gate, and a NOR gate. The inverter includes: a pull-up unit constituted by a second thin film transistor outputting a first power voltage to an output terminal according to a voltage applied to a gate; a pull-down unit constituted by a fifth thin film transistor outputting a ground voltage to the output terminal according to an input signal applied to a gate; and a pull-up driver applying a second power voltage or the ground voltage to the gate of the second thin film transistor according to the input signal.

Abstract: Markers of acute myeloid leukemia stem cells (AMLSC) are identified. The markers are differentially expressed in comparison with normal counterpart cells, and are useful as diagnostic and therapeutic targets.

Abstract: The present invention relates to a composition suitable for administration to a subject, the composition comprising pharmacologically acceptable particulate material dispersed throughout a pharmacologically acceptable liquid carrier, the particulate material being maintained in the dispersed state by a steric stabilizer, wherein the steric stabilizer is a polymeric material comprising a steric stabilizing polymeric segment and an anchoring polymeric segment, one or both of which are derived from one or more ethylenically unsaturated monomers that have been polymerized by a living polymerization technique, wherein the steric stabilizing polymeric segment is different from the anchoring polymeric segment, and wherein the anchoring polymeric segment has an affinity toward the surface of the particulate material and secures the stabilizer to the particulate material.

Abstract: A process and an apparatus for producing a composite material utilize a rotatable hollow body that is inclined with an upstream side being higher than a downstream side. A reaction zone is defined within an elongated chamber in the hollow body. Protrusions inwardly extend from an inner peripheral wall of the hollow body adjacent to the reaction zone. Base material is input into the chamber via a base material introduction port and a carbon source vapor is input into the chamber via a carbon source supply port. A heater heats the reaction zone to a temperature at which carbon nanotubes form on the base material from the carbon source vapor. The protrusions catch base material disposed on the inner peripheral wall of the hollow body when the hollow body rotates and then drop the base material through the reaction zone so that the base material contacts the carbon source vapor.

Abstract: A forceps device is provided for performing a surgical procedure. The device comprises a closeable jaw comprising jaw members having one or more force sensors deployed in a manner to measure force applied to the jaws of the device.

Abstract: The present invention provides ?2 microglobulin as a biomarker for qualifying or assessing peripheral artery disease in a subject.

Abstract: A system of the present invention is capable of detecting, imaging and measuring both neutrons and gamma rays. The system has three parallel plates each containing a plurality of detectors. Each plate has different detectors. The first plate has plastic scintillation detectors. The second plate has a plurality of stilbene scintillation detectors having pulse-shape discrimination (PSD) properties. The third plate has a plurality of inorganic detectors. The first plate and the second plate are used in connection to detect, image and measure neutrons. The second plate and the third plate are used in connection to detect, image, and measure gamma rays.

Abstract: Toxic organic materials contaminate water resources and one need to find an easy and energy efficient way to decontaminate water resources. The current invention discloses a photocatalyst Fe doped ZnO nano-particle photocatalyst that enables the decontamination process by degrading toxic organic material such as brilliant cresyl blue, indigo carmine and gentian blue by using solar light. In the current disclosure many examples of characterization of the photocatalyst, optimal working conditions and efficient use of solar light has been described. The process described to use the photocatalyst to degrade toxic organic material using the solar light to activate the photocatalyst is cost efficient and cheap to clean our water resources.

Abstract: The embodiments of the present invention are directed to discrete, cis-acting regulatory elements that include a barrier element, an insulating element, a silencing element, and matrix attachment regions (“MARs”). Additional embodiments of the present invention are directed to nucleic acid molecules that are useful for facilitating stable transgene expression within a chromatin environment. Additional embodiments of the present invention are directed to recombinant expression vectors including nucleic acid molecules of the present invention that can be incorporated into artificial chromosomes, eukaryotic cell-lines, non-human transgenic animals, and transgenic plants, to improve recombinant protein production in a broad range of eukaryotic hosts, and pharmaceutical compositions including nucleic acid molecules of the present invention that are also useful for gene therapy in the treatment of various genetic diseases.

Abstract: Provided is a compound of the formula I or a pharmaceutically acceptable salt, solvate or stereoisomer thereof: wherein Ar represents R5, R6, R7, R8, R1?, R2?, R3?, R4?, R5?, R6?, R7?, R8? independently represent H, OH, F, Cl, Br, C1 to C6 alkyl group, C1 to C6 alkoxy group, C2 to C6 alkenyl group, C2 to C6 alkenoxy group, C2 to C6 alkynyl group, C2 to C6 alkynoxy group, amine group, mono- or di-substituted amino group, cyclic C1 to C5 alkylamino group, imidazolyl group, morpholino group, piperazinyl group, optionally substituted with one or more hydroxy or halo; and X represents NH, O or S. The present invention also provides a composition comprising the compound of formula I. The compound and the composition in accordance with the present invention are effective on treating or alleviating a disease or disorder, such as malignant glioma.

Abstract: The present invention discloses a MOS transistor having a combined-source structure with low power consumption, which relates to a field of field effect transistor logic devices and circuits in CMOS ultra-large-scaled integrated circuits. The MOS transistor includes a control gate electrode layer, a gate dielectric layer, a semiconductor substrate, a Schottky source region, a highly-doped source region and a highly-doped drain region. An end of the control gate extends to the highly-doped source region to form a T shape, wherein the extending region of the control gate is an extending gate and the remaining region of the control gate is a main gate. The active region covered by the extending gate is a channel region, and material thereof is the substrate material. A Schottky junction is formed between the Schottky source region and the channel under the extending gate.

Abstract: A sensing device is used to detect the spatial distributions of stresses applied by physical contact with the surface of the sensor or induced by pressure, temperature gradients, and surface absorption. The sensor comprises a hybrid active layer that includes luminophores doped in a polymeric or organic host, altogether embedded in a matrix. Under an electrical bias, the sensor simultaneously converts stresses into electrical and optical signals. Among many applications, the device may be used for tactile sensing and biometric imaging.

Abstract: A field emission cathode structure includes a first carbon nanotube structure including a plurality of first carbon nanotubes, and a second carbon nanotube structure located on the surface of the first carbon nanotube structure. The second carbon nanotube structure includes a plurality of second carbon nanotubes substantially perpendicular to the first carbon nanotubes structure. The second carbon nanotube structure includes a peak. The heights of the second carbon nanotubes at the peak are tallest. The heights of the carbon second carbon nanotubes gradually decrease along the direction away from the peak. A method for fabricating the field emission cathode structure is also presented.

Abstract: A polymorphic systolic array framework that works in conjunction with an embedded microprocessor on an FPGA, that allows for dynamic and complimentary scaling of acceleration levels of two algorithms active concurrently on the FPGA. Use is made of systolic arrays and hardware-software co-design to obtain an efficient multi-application acceleration system. The flexible and simple framework allows hosting of a broader range of algorithms and extendable to more complex applications in the area of aerospace embedded systems.

Abstract: The invention relates to histology analyses, and in particular, to the assessment of pathological tissues to aid in the diagnosis of disease characterized by specific pathologies, for example cancer. The invention provides methods and apparatuses for analyzing tissue samples, as well as computer-readable media programmed with software for carrying out these diagnostic methods.

Abstract: A high safety vehicular transportation system is used in an individual carpool car with at least one user and comprises a user module, a rescue unit and a server center. The user module stores and provides carpool data, stores and provides states of individual carpool car, submits a carpool request and comprises a save our soul (SOS) system. The SOS system transmits a distress signal. The rescue unit provides emergency rescue assistance if any user is in a dangerous situation. The server center receives, stores and provides carpool data, has an instantaneous tracking capability, provides carpool service to at least one user, calls the rescue unit if the server center receives the distress signal, receives the carpool request and generates at least one carpool mission to fulfill the carpool request. An operational method for a high safety vehicular transportation system is also disclosed.

Abstract: The present invention compositions and methods of using at least a portions of an isolated and purified ?-crystallin polypeptide that includes one or more ?-pleated sheets and that prevents neurotoxicity and amyloidogenesis.

Abstract: A surgical simulator is disclosed herein. The surgical simulator includes an artificial organ and an enclosure substantially enclosing the artificial organ. The artificial organ is substantially formed of platinum cured room temperature vulcanization silicone rubber (“PCRTVS”).

Abstract: Disclosed is a positive electrode active material for nonaqueous electrolyte secondary batteries which contains a complex oxide mainly containing sodium, nickel and a tetravalent metal while having a hexagonal structure. This positive electrode active material enables to obtain a nonaqueous electrolyte secondary battery with high operating voltage. The complex oxide is preferably expressed as Na[Na(1/3-2x/3)Ni(x-y)M(2/3-x/3-y)A2y]O2 (wherein M represents one or more tetravalent metals, A represents one or more trivalent metals, 0<x?0.5, 0?y<1/6, and x>y).