Patents Assigned to University
  • Patent number: 6730779
    Abstract: The invention provides an isolated gene encoding Mch4 or an isolated gene encoding Mch5 as well as functional fragments thereof. Also provided are isolated nucleic acid sequences encoding Mch4 or Mch5 or functional fragment thereof. The gene or nucleic acid sequences can be single or double stranded nucleic acids corresponding to coding or non-coding strands of the Mch4 or Mch5 nucleotide sequences. Also provided are genes and nucleic acids encoding functional fragments such as the FADD-like domains Mch4A, Mch4B, Mch5A and Mch5B. Isolated Mch4 or Mch5 polypeptides or functional fragments thereof including the FADD-like domains Mch4A, Mch4B, Mch5A and Mch5B are also provided.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: May 4, 2004
    Assignees: IDUN Pharmaceuticals, Inc., Thomas Jefferson University
    Inventors: Emad S. Alnemri, Teresa Fernandes-Alnemri, Gerald Litwack, Robert Armstrong, Kevin Tomaselli
  • Patent number: 6730224
    Abstract: An improved method for the aerobic thermophilic treatment of organic material of the type in which air is passed through organic matter contained in a reactor, in which at least a portion of the air that has passed through the organic matter in the reactor being captured and again passed through the organic matter.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: May 4, 2004
    Assignee: Board of Trustees of Southern Illinois University
    Inventor: James W. Blackburn
  • Patent number: 6730119
    Abstract: A low profile, abdominal aortic aneurysm exclusion device with iliac vessel extensions. A sectional, bifurcated stent forms part of an endoluminal prosthesis to eliminate or reduce the risk of rupture of aortic aneurysms. An apparatus and a method for introducing the bifurcated stent in sections into the vasculature and assembling the sections in situ to form a “scaffold” for introduction of material to re-endothelialize and/or occlude the aneurysm cavity. After trans-stent embolization of the aneurysm cavity with thrombogenic material, laminar flow stimulates endothelialization of the stent lumen. Subsequent organization and fibrosis of the persistent thrombus reinforces the wire-mesh or etched metal tubular scaffold comprising the stent and serves to stabilize and shrink the aneurysm. A single stent deployed with the same method may be used in non-bifurcated vessels.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: May 4, 2004
    Assignee: Board of Regents of the University of Texas System
    Inventor: Richard W. Smalling
  • Patent number: 6730036
    Abstract: Ultrasonic imaging to receive a signal from contrast agent microbubbles in arterioles of a myocardium, without being masked by a signal from microbubbles in capillaries of the myocardium. For example, high power ultrasonic energy is emitted to destroy microbubbles in the arterioles and capillaries. A time delay passes from the destruction. The time delay is sufficiently long to allow the arterioles to refill with microbubbles and sufficiently short so that the capillaries do not completely refill with microbubbles. Ultrasonic imaging is then performed to receive a signal between harmonics from the microbubbles refilled in the arterioles. Various other destructive and non-destructive imaging techniques are disclosed.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: May 4, 2004
    Assignees: Koninklijke Philips Electronics, N.V., University of Virginia
    Inventors: Patrick G. Rafter, Jerome F. Witt, Sanjiv Kaul, Kevin Wei, George A. Brock-Fisher
  • Patent number: 6730826
    Abstract: The present invention relates to a trichome specific regulatory sequence.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: May 4, 2004
    Assignee: University of Kentucky Research Foundation
    Inventors: George J. Wagner, Susheng Gan, Erming Wang, Rui Wang
  • Patent number: 6730634
    Abstract: The invention relates to a method of identifying herbicides and to the use of inhibitors of plant peptide deformylase as broad spectrum herbicides.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: May 4, 2004
    Assignee: University of Kentucky Research Foundation
    Inventors: Robert L. Houtz, Lynnette M. A. Dirk, Mark Alan Williams
  • Patent number: 6730537
    Abstract: A method for forming arrays of metal, alloy, semiconductor or magnetic clusters is described. The method comprises placing a scaffold on a substrate, the scaffold comprising, for example, polynucleotides and/or polypeptides, and coupling the clusters to the scaffold. Methods of producing arrays in predetermined patterns and electronic devices that incorporate such patterned arrays are also described.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: May 4, 2004
    Assignee: The State of Oregon acting by and through the State Board of Higher Education on behalf of the University of Oregon
    Inventors: James E. Hutchison, Scott M. Reed
  • Patent number: 6731767
    Abstract: In one embodiment an apparatus for processing sound includes a means (401) for analyzing a sound signal into a number frequency bands and a means (403) for applying variable gain to each frequency band independently. Gain is applied under control of a number of gain comparator means (409) each of which generates a number of statistical estimates in respect of each signal and compares those estimates to predetermined hearing response parameters stored in memory (411). The numerous gain compensated frequency bands are then combined (415) in order to generate a single sound signal. The apparatus may be implemented in dedicated hardware embodiment or by software running on a microprocessor.
    Type: Grant
    Filed: January 5, 2000
    Date of Patent: May 4, 2004
    Assignee: The University of Melbourne
    Inventors: Peter John Blamey, Christopher John James, Konrad Wildi, Hugh Joseph McDermott, Lois Martin
  • Patent number: 6730443
    Abstract: A method for patterning a layer on a substrate can include projecting coherent radiation toward a reflector surface so that the coherent radiation is reflected off the reflector surface to provide a holographic projection of a desired image wherein the reflector surface includes information that corresponds to an inverse of the holographic projection of the desired image. The substrate including the layer can be maintained in the path of the reflected radiation so that the holographic projection is projected onto the layer. Related systems are also discussed.
    Type: Grant
    Filed: February 12, 2001
    Date of Patent: May 4, 2004
    Assignee: University of Tennessee Research Foundation
    Inventors: Daniel J. C. Herr, David Charles Joy
  • Patent number: 6730775
    Abstract: The present invention provides methods, kits, and pharmaceutical compositions for limiting scar or adhesion formation by administration of angiotensinogen, AI, AI analogues, and/or AI fragments and analogues thereof, AII analogues, AII fragments or analogues thereof, ACE inhibitors, AII AT2 type 2 receptor agonists, either alone or in combination with other compounds.
    Type: Grant
    Filed: March 22, 2000
    Date of Patent: May 4, 2004
    Assignee: University of Southern California
    Inventors: Kathleen E. Rodgers, Gere diZerega
  • Patent number: 6730297
    Abstract: Gene delivery vectors, for example, recombinant FIV vectors, and methods of using such vectors are provided for use in treating or preventing retinal diseases of the eye and diseases of the brain associated with lysosomal storage disorders.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: May 4, 2004
    Assignees: Chiron Corporation, University of Iowa Research Foundation
    Inventors: Beverly Davidson, Douglas J. Jolly, Sybille L. Sauter, Colleen S. Stein, Thomas W. Dubensky, Jr., Jason A. Heth
  • Patent number: 6729039
    Abstract: A method and an apparatus for controlling airflow in a desiccant drying system having two desiccant beds (10, 12). A first diverter valve (14) communicates with each of the desiccant beds, a regeneration air inlet (22), and a press air outlet (20). A second diverter valve (16) communicates with each of the desiccant beds, a process air inlet (18), and a regeneration air outlet (28). First and second regeneration air control valves (24, 30) are also provided which during a cooling phase of the regeneration cycle admit a cooling bleed stream of process air to the desiccant bed being regenerated and then convey the cooling air bleed stream from the desiccant bed and through a heat exchanger (42) back to the process air inlet.
    Type: Grant
    Filed: July 21, 2003
    Date of Patent: May 4, 2004
    Assignee: Universal Dynamics, Inc.
    Inventor: Robert R. Crawford
  • Patent number: 6730475
    Abstract: The invention features methods of diagnosing and treating Meniere disease. The invention also features kits and probes for diagnosing Meniere disease.
    Type: Grant
    Filed: May 25, 2000
    Date of Patent: May 4, 2004
    Assignees: Brigham and Women's Hospital, University of Antwerp
    Inventors: Nahid Robertson, Cynthia Morton, Guy Van Camp, Erik Fransen, Paul Van de Heyning
  • Patent number: 6730686
    Abstract: The instant invention provides compositions and methods for modeling post-Amadori AGE formation and the identification and characterization of effective inhibitors of post-Amadori AGE formation, and such identified inhibitor compositions. The instant invention also teaches new methods to treat or prevent oxidative modification of proteins, including low density lipoproteins, to treat or prevent lipid peroxidation, and to treat or prevent atherosclerosis, comprising administering an amount effective of one of the compounds of the invention to treat or prevent the disorder.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: May 4, 2004
    Assignees: Kansas University Medical Center, University of South Carolina
    Inventors: John W. Baynes, Joelle Onorato, Suzanne Thorpe, Raja Khalifah, Billy G. Hudson
  • Patent number: 6730501
    Abstract: A method and device are described for analyzing a sample for the presence of an analyte wherein the analyte is contacted with a substrate to effect a measurable change selected from the group consisting of the quantity of the analyte, the quantity of the substrate, and the quantity of an optical or physical change to the substrate, wherein the analyte is contacted with the substrate for a predetermined time period, to generate a signal related to the measurable change. Scores are obtained from various tests performed on the signal data, and the scores are used to determine whether the substrate is present in the sample.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: May 4, 2004
    Assignee: University of Utah Research Foundation
    Inventors: David J. Eyre, Carl T. Wittwer
  • Patent number: 6730812
    Abstract: The present invention provides a method of preparing a phosphonium salt of the formula [R1R2R3P—CR4R5R6]X, comprising ball-milling a phosphine of the formula R1R2R3P with a compound of the formula XCR4R5R6; a method of preparing a phosphorus ylide of the formula R1R2R3P═CR4R5, comprising ball-milling a phosphonium salt of the formula [R1R2R3P—HCR4R5]X in the presence of a base; and a method of preparing an olefin of the formula R4R5C═CR7H or R4R5C═CR7R8, comprising ball-milling a phosphorus ylide of the formula R1R2R3P═CR4R5 with a compound of the formula R7C(O)H or R7C(O)R8. The inventive method produces phosphonium salts and phosphorus ylides by mechanical processing solid reagents under solvent-free conditions.
    Type: Grant
    Filed: February 5, 2003
    Date of Patent: May 4, 2004
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Vitalij K. Pecharsky, Viktor P. Balema, Jerzy W. Wiench, Marek Pruski
  • Patent number: 6729607
    Abstract: A cable release anchor having an improved breakaway post design with a cable release feature. The cable release anchor includes upper and lower anchor portions that are readily separable from one another during an impact. A bearing plate is retained within the end of each of the upper and lower anchor portions, and each bearing plate has a bearing surface that is oriented at an acute angle with the vertical when installed in the ground. Each of these bearing plates contains a U-shaped cutout. When the upper and lower anchor portions are joined, the cutouts form an opening through which an end of the tension cable is disposed. An impact to the upper anchor portion readily releases the upper post section from the lower post section and frees the cable. The cable release anchor provides positive anchorage to react to tensile loads on a rail member to redirect a vehicle impacting along the length of the terminal or guardrail.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: May 4, 2004
    Assignee: Texas A&M University System
    Inventors: Dean C. Alberson, D. Lance Bullard, Jr., Roger P. Bligh, C. Eugene Buth
  • Patent number: 6730075
    Abstract: The present invention provides a surgical probe having a tip for use in liquid media, wherein the tip has a concave body portion and a distal portion. The concave body portion of the tip is positioned immediately adjacent the distal portion such that the liquid jet resulting from the collapse of the cavitation bubble can be substantially reduced. Also disclosed is a surgical probe having a tip and an obstacle for use in liquid media, wherein the tip has a body portion and a distal portion. The obstacle is mounted on the outside of the probe such that the liquid jet resulting from the collapse of the cavitation bubble can be substantially reduced. The obstacle can also be a pick positioned on one side of the probe and in front of the probe.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: May 4, 2004
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Daniel V. Palanker, Alexander Vankov
  • Patent number: 6732247
    Abstract: Multi-ported pipelined memory is located on a processor die serving as an addressable on-chip memory for efficiently processing streaming data. The memory sustains multiple wide memory accesses per cycle, clocks synchronously with the rest of the processor, and stores a significant portion of an image. Such memory bypasses the register file directly providing data to the processor's functional units. The memory includes multiple memory banks which permit multiple memory accesses per cycle. The memory banks are connected in pipelined fashion to pipeline registers placed at regular intervals on a global bus. The memory sustains multiple transactions per cycle, at a larger memory density than that of a multi-ported static memory, such as a register file.
    Type: Grant
    Filed: January 17, 2001
    Date of Patent: May 4, 2004
    Assignee: University of Washington
    Inventors: Stefan G. Berg, Donglok Kim, Yongmin Kim
  • Patent number: PP14749
    Abstract: A new and distinct Chrysanthemum plant named ‘MN90-275-27’ is provided.
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: May 4, 2004
    Assignee: University of Minnesota
    Inventors: Neil Anderson, Peter Ascher