Abstract: The present invention relates to a method for preparing microspheres and microspheres prepared thereby, more particularly to a method for preparing a polymeric microsphere, including preparing an emulsion including a polymer compound, a drug, a water-insoluble organic solvent and a dispersion solvent and adding to the prepared emulsion a base or an acid to remove the water-insoluble organic solvent from the emulsion, a polymeric microsphere prepared thereby, and a composition for drug delivery including the microsphere. According to the present invention, a drug-containing polymer microsphere may be prepared quickly and simply without the solvent evaporation or solvent extraction process, thereby reducing water consumption and minimizing wastewater generation.

Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.

Abstract: A method of optimizing parametric gain in a nonlinear optical crystal that in response to application of a pump beam generates through a parametric generation process signal and idler beams, wherein the signal beam is non-collinear with the pump beam and the signal beam is subject to absorption due to the nonlinear material, the method involving shaping the pump beam to have an elliptical cross section, wherein the method further involves determining the width w of the pump beam depending on the absorption co-efficient of the optical crystal.

Abstract: The present invention relates to a compound of the general formula (I) useful in the determining the presence, amount or activity of an enzyme in living cells, a method of preparing said compounds and a kit thereof.

Abstract: An apparatus and method for producing and storing ice on the sea using sub-zero cold air of the winter season, to achieve an earlier freezing period, and increasing the area and thickness of the ice layer, to suppress the melting of ice sheets and glaciers and suppress and overcome global warming as well as its side effects. The apparatus and method involve compressing cold air; injecting the compressed cold air into a storage tank; supercooling water using the injected cold air; forming an ice layer by misting the supercooled water into the sea; and increasing a thickness of the ice layer by additionally misting water onto the ice layer formed at water level.

Abstract: Disclosed are compositions and methods for related to monoclonal antibodies specific for single amino acid variation in an antigen.

Abstract: Immunogenic compositions are provided herein that are useful for inducing an immune response specific against group A streptococcus (GAS). Immunogenic compositions provided herein are multivalent and comprise a plurality of immunogenic peptides or fusion polypeptides comprising the immunogenic peptides that induce an immune response against GAS. The immunogenic compositions provided herein induce an immune response against the GAS serotypes represented by an immunogenic peptide (derived from an M protein or Spa protein) comprised within the immunogenic composition and also induce an immune response against serotypes that are unrepresented by any immunogenic peptide included in the immunogenic composition. Methods for using the compositions for inducing an immune response against GAS and for treating or reducing the likelihood of occurrence of a GAS infection are also provided.

Abstract: A microtensiometer sensor includes a substrate layer fluidly coupled to an enclosed reservoir. A porous membrane is disposed on a surface of the substrate layer. The membrane defines a liquid side fluidly coupled to the reservoir and a vapor side fluidly coupled to a vapor interface. The porous membrane includes a plurality of through holes fluidly coupling the liquid reservoir to the vapor interface, and a nanoporous filler material disposed within the plurality of through holes. The filler material includes a plurality of open pores having a maximum diameter in the range of 0.2 to 200 nanometers. In one embodiment, the microtensiometer sensor includes a molecular membrane disposed adjacent to the vapor side of the porous membrane. In one example, the molecular membrane is formed of a highly crystalline polytetrafluoroethylene polymer having a microstructure characterized by nodes interconnected by fibrils.

Abstract: A method and device for evaluating a solar cell each of which makes it possible to easily evaluate a defect of a solar cell especially in such a manner that an internal cause defect and an external cause defect are distinguished from each other. The device includes: electric current passing means for passing, in a forward direction, an electric current through a solar cell element constituting the solar cell; light emission detecting means for detecting, out of light emitted from the solar cell element due to the electric current passed by the electric current passing means, light in a first range of wavelengths from 800 nm to 1300 nm and light in a second range of wavelengths from 1400 nm to 1800 nm; and judging means for distinguishing between an internal cause defect and an external cause defect.

Abstract: An asphalt binder includes asphalt and an asphalt binder modifier, which includes bio-oil. The asphalt binder can include a carboxyl additive. The asphalt can optionally include polymer-modified asphalt. An asphalt material includes mineral aggregate, an asphalt material binder including asphalt, and an asphalt binder modifier including bio-oil. A method for making the asphalt binder is disclosed. The asphalt material includes asphalt pavement and roofing shingles. The asphalt binder can be emulsified with water and a surfactant for use as a weatherproofing sealant or as an adhesive.

Abstract: A method and apparatus for estimating error in a multi-axis controlled machine is applicable to any type of machine configuration in order to estimate and confirm in advance the final position and the posture of the machine, which are produced when geometric errors of the machine are synthesized. The method includes defining the structure of the multi-axis controlled machine subjected to error estimation; and defining parameters, which represent behaviors of drive axes having geometric error and relationships between the drive axes according to the defined structure of the multi-axis controlled machine, adding the defined parameters by applying the parameters to a generalized error synthesis model, and generating an error synthesis model of the multi-axis controlled machine by applying a result of parametric modeling in response to a result of the adding.

Abstract: Disclosed is a diagnostic marker for lung cancer comprising Hp?R as an active ingredient. Because blood, which is relatively easy to sample, is employed as a specimen, the diagnostic kit and marker for lung cancer is very simple and does not subject patients to a load compared to conventional methods that are directed to a biopsy. In addition, the kit and marker of the present invention is useful in the early diagnosis of lung cancer thanks to its high diagnostic sensitivity and selectivity.

Abstract: The invention relates to micelles that are elaborated with functionality useful for imaging and/or selectively targeting tissue, e.g., in the delivery of hydrophobic agents.

Abstract: The vehicle flotation system is adaptable to a conventional land motor vehicle to provide sufficient buoyancy for the vehicle should it become immersed in water. A plurality of permanently inflated pneumatic elements and/or solid closed-cell (e.g., foam, cork, etc.) elements is installed throughout the bodywork of the vehicle. Such permanently inflated and solid flotation elements do not require a pneumatic inflation system, thus providing benefits in reliability and economy. Optionally, a pneumatic inflation monitoring system may be provided for the pneumatic elements. As an additional option, a plurality of collapsed, inflatable elements may be installed within the vehicle fenders for deployment and inflation in the event of water immersion of the vehicle. These inflatable elements are automatically ejected laterally from slots or openings in the vehicle fenders and are automatically inflated by an on-board container of compressed gas, in the event of water immersion of the vehicle.

Abstract: Image data is processed to facilitate focusing and/or optical correction. According to an example embodiment of the present invention, an imaging arrangement collects light data corresponding to light passing through a particular focal plane. The light data is collected using an approach that facilitates the determination of the direction from which various portions of the light incident upon a portion of the focal plane emanate from. Using this directional information in connection with value of the light as detected by photosensors, an image represented by the light is selectively focused and/or corrected.

Abstract: The invention relates to a photonic crystal four-port circulator based on the coupling of magneto-optical cavities, which comprises two same magneto-optical cavities and three waveguides which are symmetrically distributed on the periphery of each magneto-optical cavity, wherein two waveguides connected with the magneto-optical cavities respectively are in a “v-shaped” arrangement, thereby guaranteeing that waveguides which are connected with the left sides of the two magneto-optical cavities are parallel to each other and waveguides which are connected with the right sides of the two magneto-optical cavities are parallel to each other as well and achieving the high-efficiency transmission in the case of the coupling of the magneto-optical cavities.

Abstract: Provided are hemoglobins having at least two chemical modifications that lower oxygen affinity, hemoglobins chemically modified by the addition of glyceraldehyde-3-phosphate, and hemoglobins having at least two specific chemical modifications. PEGylated versions of these hemoglobins are also provided, as are certain tetraPEGylated and diPEGylated hemoglobins. Methods of modifying a hemoglobin are additionally provided, as are methods of making a hemoglobin. Pharmaceutical compositions and blood substitutes using these hemoglobins are further provided, as are methods of treating a subject using these pharmaceutical compositions and blood substitutes.

Abstract: A plasma sterilizing device has a container for a long tubule to be sterilized, having an adjustable internal pressure, and an electrode provided at at least one end of the long tubule. The device is configured so that plasma is generated inside the long tubule by applying an alternating current voltage to the electrode in such a state that the pressure inside and outside of the long tubule can be adjusted, so that there is a predetermined difference in pressure between the inside and the outside of the long tubule.

Abstract: The present invention relates to the preparation of hyperpolarized 89Y. Hyperpolarized 89Y may be used as nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) agents for sensitive detection and imaging.

Abstract: The present invention relates to a resin composition for moisture absorbing film comprising polyethylene resin and polyacrylic acid partial sodium salt (PAPSS) or attapulgite synthesized acrylic amide (ATPGAA) as a moisture absorbent, moisture absorbing film for packaging, and a method for manufacturing film, and the present invention also relates to a resin composition for seasoned laver packaging film to be used for maintaining the high quality of the merchandize with good taste and tissue dryness.