Abstract: Implantable pressure-actuated systems to deliver a drug and/or other substance in response to a pressure difference between a system cavity and an exterior environment, and methods of fabrication and use. A pressure-rupturable membrane diaphragm may be tuned to rupture at a desired rupture threshold, rupture site, with a desired rupture pattern, and/or within a desired rupture time. Tuning may include material selection, thickness control, surface patterning, substrate support patterning. The cavity may be pressurized above or evacuated below the rupture threshold, and a diaphragm-protective layer may be provided to prevent premature rupture in an ambient environment and to dissipate within an implant environment. A drug delivery system may be implemented within a stent to release a substance upon a decrease in blood pressure. The cavity may include a thrombolytic drug to or other substance to treat a blood clot.

Abstract: A video transmission method is provided, which includes receiving state information from at least one mobile terminal that intends to perform a video stream service through a wireless network, determining a size of an image by selecting a specified spatial layer bit stream on the basis of the state information of the mobile terminal from a plurality of spatial layer bit streams generated at different bit rates during encoding of the bit stream, selecting a specified time and an SNR layer bit stream by increasing or decreasing time of the image and a layer position of the SNR layer bit stream on the basis of network parameters included in the state information of the mobile terminal, and transmitting the bit stream generated by extracting the specified layer bit stream of the selected layer to the mobile terminal.

Abstract: In an embodiment, a plurality of transactions for accessing a database may be acquired. The database may be associated with a plurality of locks. The plurality of transactions may include a first transaction, a second transaction, and a third transaction. A logical serialization sequence for executing the transactions may be identified. The logical serialization sequence may indicate that (1) the first transaction is to be executed before the second transaction based on all locks that are required by the first transaction being available; (2) the second transaction is to be executed after the first transaction has completed execution based on the second transaction requiring a lock that is required by the first transaction; and (3) the third transaction is to be executed before or during execution of the first transaction based on all locks required by the third transaction being different than the locks required by the first transaction.

Abstract: The present invention relates to the use of self-assembling peptide amphiphiles to prevent tumor formation by transplanted stem cells. The present invention further relates to the use of self-assembling peptide amphiphiles to treat cancers.

Abstract: The pressure sensitive adhesive is a copolymer of ethylene and propylene that has a maximum load between 6.4 N and 11.2 N in a lap joint shear strength test. The copolymer is prepared by mixing ethylene and propylene in the presence of a diimine nickel catalyst and polymethylaluminoxane (MAO) co-catalyst. The molar ratio of the ethylene to propylene feed is between 60:40 and 40:60. The polymerization is carried out at 30° C. and 1.3 bar. The polypropylene molar percentage in the resulting copolymer is between 42% and 88%, and the weight average molecular weight is between 24,917 and 33, 314 Da. The copolymer is an amorphous polymer having a glass transition temperature (Tg) between ?63° C. and ?66° C.

Abstract: The invention relates to isolated DNA or RNA molecules comprising at least ten contiguous bases having a sequence in a pancreatic islet microRNA. In another embodiment, the invention relates to isolated single stranded pancreatic islet microRNA molecules or anti-pancreatic islet microRNA molecules.

Abstract: A plunger type water pump mainly comprises a cavity body, a rotary main shaft and a plunger flow-distributing unit. The plunger flow-distributing unit comprises a flat valve assembly, a plunger-shoe assembly and a supporting valve assembly. The plunger-shoe assembly divides the cavity body into a high-pressure cavity and a low-pressure cavity independent of each other. The high-pressure cavity is in fluid communication with the flat valve assembly; and the low-pressure cavity is in fluid communication with the supporting valve assembly. The high-pressure water and the low-pressure water are independent of each other. This arrangement ensures a high volumetric efficiency of the water pump under ultra-high-pressure conditions and provides fluid support and lubrication for a friction coupling under high-speed heavy-load conditions to prolong the service life of the water pump.

Abstract: Provided is a cell cultivation method in which the cell is cultured using a peptide hydrogel as a scaffold, for carrying out high-dimensional culture of a cell such as porcine hepatocyte, human hepatocyte, porcine pancreatic islet or human pancreatic islet for a long period under conditions where cell survival, cell morphology and cell functions are maintained. Also provided are a cell culture including a cell and a peptide hydrogel obtained by the above-described cultivation method, a bioreactor including the cell culture, and a cell preparation including the cell culture.

Abstract: The present invention relates to a method for in vivo detection of a biofilm infection residing in a mammal, the method comprising (i) administering to the mammal a diagnostic-effective amount of a biofilm-specific probe, wherein the probe comprises a bio film-targeting moiety and a paramagnetic nanoparticle core; and (ii) imaging the mammal to detect the presence of the biofilm infection by observing the mammal using a magnetic resonance diagnostic technique after the biofilm-specific probe has been provided sufficient time to selectively bind to the bio film infection that may be present in the mammal. The invention also relates to methods of treatment of a bio film infection, and compositions and kits useful in the detection and/or treatment of bio film infections.

Abstract: A chiral synthesis of pyrrolidine compounds en route to selective neuronal nitric oxide synthase inhibitors, and representative inhibitor compounds heretofore unattainable.

Abstract: Posterior spinal stabilization devices that engage vertebral structures of at least two verterbrae and increase the stability between the two vertebrae. In some embodiments the stabilization devices engage laminae of at least two vertebrae. The devices can be adapted, however, to engage at least one of a variety of vertebral structures (e.g., spinous process, lamina, transverse process, etc.) of a plurality of vertebrae to decrease vertebral motion between at least two vertebrae.

Abstract: The present invention discloses a channel estimation method for an orthogonal frequency-division multiplexing system with cyclic-delay diversity. The method makes pilots have the same amplitude and equally partitions the pilots into a number of pilot groups. In addition, the method equally spaces the pilots of each group in a frequency domain and determines the pilot locations and cyclic-delay coefficient of each pilot group in order to optimize the channel estimation of a receiver. The method can perform the channel estimation by using just one OFDM symbol.

Abstract: The gene responsible for encoding SERT has a functional polymorphism at the 5?-regulatory promoter region, which results in two forms, long (L) and short (S). The LL-genotype is hypothesized to play a key role in the early onset of alcohol use. The present invention discloses the differences in treatment and diagnosis based on the L or short genotypes as well as on a single nucleotide polymorphism of the SERT gene, the 3? UTR SNP rs 1042173. The present invention demonstrates the efficacy of using the drug ondansetron and similar drugs for treatment based on variations in the polymorphisms of the SERT gene as well as methods for diagnosing susceptibility to abuse of alcohol and other addiction-related diseases and disorders.

Abstract: The invention discloses an intermediate 1-methoxyl-2,6,10-trimethyl-1,3,5, 9-undec-tetraene, and a preparation method and uses thereof. In the synthesis method for the current lycopene intermediate 2-pos double bond C-14 aldehyde (2,6,10-trimethyl-2,5,9-undecatriene-1-aldehyde), expensive methyl iodide, polluting dimethyl sulphide and dangerous strong base are needed, so that the method is hardly applied to industrial production. The invention provides a new compound 1-methoxyl-2,6,10-trimethyl-1,3,5,9-undec-tetraene, and pure 2-pos double bond C-14 aldehyde can be prepared by hydrolyzing and refining the compound. The synthetic route is simplified and the great suitability for industrial production is achieved.

Abstract: In one aspect, the invention relates to substituted (1-(methylsulfonyl)azetidin-3-yl)(heterocycloalkyl)methanone analogs, derivatives thereof, and related compounds, which are useful as antagonists of the muscarinic acetylcholine receptor M1 (mAChR M1); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: Improved anti-HIV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus sequences for HIV Subtype A Envelope protein, those having consensus sequences for HIV Subtype B Envelope protein, those having consensus sequences for HIV Subtype C Envelope protein, those having consensus sequences for HIV Subtype D Envelope protein, those having consensus sequences for HIV Subtype B consensus Nef-Rev protein, and those having consensus sequences form HIV Gag protein subtypes A, B, C and D. Improved anti-HPV immunogens and nucleic acid molecules that encode them; improved anti-HCV immunogens and nucleic acid molecules that encode them; improved hTERT immunogens and nucleic acid molecules that encode them; and improved anti-Influenza immunogens and nucleic acid molecules that encode them are disclosed as well methods of inducing an immune response in an individual against HIV, HPV, HCV, hTERT and Influenza are disclosed.

Abstract: Methods for producing greater biomass in a plant, increasing the drought tolerance of a plant, producing a decreased lignin concentration in a plant, producing a greater iron concentration in a plant, or inhibiting fungal infection in a plant comprise administering Bacillus subtilis FB17 to the plant, the seed of the plant, or soil surrounding the plant or the seed in an amount effective to produce greater biomass, increase the drought tolerance, produce a decreased lignin concentration, produce a greater iron concentration, or inhibit fungal infection in the plant compared to an untreated plant, respectively. Agricultural carriers and seed coatings comprising Bacillus subtilis FB17 are provided. The biomass of a plant which has been administered Bacillus subtilis FB17 can be converted to a biofuel or can be used as a food crop or in other uses.

Abstract: A method of treating motor deficits in a stroke patient, comprising assessing a patient's motor deficits, determining therapeutic goals for the patient, based on the patient's motor deficits, selecting therapeutic tasks based on the therapeutic goals, performing each of the selected therapeutic tasks repetitively, observing the performance of the therapeutic tasks, initiating the stimulation of the vagus nerve manually at approximately a predetermined moment during the performance of the therapeutic tasks, stimulating the vagus nerve of the patient during the performance of the selected therapeutic tasks, and improving the patient's motor deficits.

Abstract: A screen device for three-dimensional display with full viewing-field comprises a display screen (2), a rotation device (3) for the display screen, and an optical device (1) disposed in front side of the display screen (2). The optical device (1) may be a two dimensional diaphragm array (5) with inclined openings, a vertical lenticular lens array (6), a combination of a two dimensional diaphragm array (7) with vertical openings and a lens (8), or a combination of a two dimensional micro-lens array (9), a vertical diffusion screen (10) and a cylindrical lens (11).

Abstract: The present invention provides a peptide which functions as a mimic peptide of an amyloid ? peptide and is capable of inhibiting the fibrillogenesis of an amyloid ? peptide. The present invention relates to an 8- to 30-amino acid residue peptide comprising an amino acid sequence represented by the following formula (I): X1-Asp-X2-X3-X4-Pro-X5-X6 (SEQ ID NO: 28) (I), wherein X1 represents a branched chain amino acid, and X2, X3, X4, X5, and X6 are the same or different and each represents an ?-amino acid, and to a pharmaceutical composition and an amyloid ? fibrillogenesis inhibitor comprising the peptide.