Abstract: A system, method and computer-readable medium for mapping magnetic activity for a current linking a planet's space environment to an ionosphere of the planet are disclosed. Magnetic field measurements of the current are obtained from a plurality of satellites orbiting the planet. A residual magnetic field is determined from the obtained magnetic field measurements. The determined residual magnetic field is arranged to create a time series for a selected location of a planet-centered coordinate system. The magnetic activity is mapped using the created time series for the selected location.
Type:
Grant
Filed:
April 19, 2012
Date of Patent:
April 1, 2014
Assignee:
The Johns Hopkins University
Inventors:
Brian J. Anderson, Lars P. Dyrud, Jonathan T. Fentzke, Robin J. Barnes
Abstract: A distributed media access system and method. The method includes making each of a plurality nodes in a P2P network designate at least one nearest neighbors as a first node candidate and perform at least one random walk to obtain a second node candidate according to the peer list; calculating user preferences of the request node and user preferences of the first and second node candidates according to the first and second node candidates and the preference parameters corresponding to the first and second node candidates so as to obtain a plurality of similarity values; selecting the more similar candidate as buddies of user of the node according to the calculated similarity values; and establishing a buddy list according to the buddies of user and storing the buddy list such that the P2P network can quickly find buddies of the node through the buddy list.
Abstract: The present disclosure relates to methods, devices, and systems used for the treatment of and/or promoting recovery from various neurological disorders and conditions, including epilepsy and other seizure disorders and movement and other related disorders; for promoting recovery from acute or chronic brain injury (e.g. stroke, hypoxia/ischemia, head trauma, subarachnoid hemorrhage, and other forms of brain injury, for awakening and/or promoting the recovery of patients in various levels of coma, altered mental status or vegetative state); or for promoting recovery from chronic daily headache and migraine and related disorders via external (cutaneous) stimulation of the sensory branches of the trigeminal nerve in the face and forehead. More specifically, devices and electrode assemblies configured for stimulation of the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and infratrochlear nerves are disclosed.
Type:
Grant
Filed:
October 5, 2010
Date of Patent:
April 1, 2014
Assignee:
The Regents of the University of California
Inventors:
Christopher DeGiorgio, Ian A. Cook, Alejandro Covalin
Abstract: The present invention provides methods for guiding preservation of neurons or nerves during surgery by administering a fluorescently-labeled peptide or aptamer that specifically binds to the neurons or nerves. The invention further provides targeting molecules of fluorescently-labeled peptides or aptamers that specifically bind to neurons or nerves and for compositions thereof.
Type:
Grant
Filed:
April 15, 2010
Date of Patent:
April 1, 2014
Assignee:
The Regents of the University of California
Inventors:
Roger Y. Tsien, Quyen T. Nguyen, Michael Whitney
Abstract: A capillary column (10) includes a tube structure having inner walls (14) and a sol-gel substrate (16) coated on a portion of inner walls (14) to form a stationary phase coating (18) on inner walls (14). The sol solution used to prepare the sol-gel substrate (16) has at least one baseline stabilizing reagent and at least one surface deactivation reagent resulting in the sol-gel substrate (16) having at least one baseline stabilizing reagent residual and at least one surface deactivating reagent residual. A method of making the sol-gel solution is by mixing suitable sol-gel precursors to form the solution, stabilizing the solution by adding at least one baseline stabilization reagent, deactivating the solution by adding at least one surface deactivation reagent to the solution, and reacting the solution in the presence of at least one catalyst.
Type:
Grant
Filed:
November 13, 2006
Date of Patent:
April 1, 2014
Assignee:
University of South Florida
Inventors:
Abdul Malik, Abuzar Kabir, Chetan Shende
Abstract: This invention provides methods of diagnosing or determining a cause of an autoimmune encephalitis or an epilepsy in a subject and of diagnosing a tumor in a subject, comprising the step of testing a biological sample of the subject for an anti-body to a GABAB receptor. This invention further provides methods of treating an autoimmune encephalitis or an epilepsy, comprising the steps of detecting an antibody to a GABAB receptor and treating a tumor associated with the disease.
Type:
Grant
Filed:
September 29, 2010
Date of Patent:
April 1, 2014
Assignee:
The Trustees of the University of Pennsylvania
Abstract: Interaction between insulin-like growth factor 1 (IGFI) and integrin is involved in integrin-mediated cellular signaling, such as enhanced proliferation of cells expressing integrins, especially integrin alpha v beta 3, alpha 6 beta. 1 and alpha 6. beta. 4. A method for inhibiting integrin signaling by using an inhibitor of IGFI-integrin binding is disclosed A method for identifying inhibitors of IGFI-integrin binding is also described. Further disclosed are polypeptides, nucleic acids, and corresponding compositions for inhibiting integrin signaling.
Type:
Grant
Filed:
January 29, 2010
Date of Patent:
April 1, 2014
Assignee:
The Regents of the University of California
Abstract: The present disclosure relates generally to a pharmaceutical compositions and methods of reducing acetaminophen-induced liver toxicity. The disclosure includes pharmaceutical compositions including acetaminophen and one or more components selected from S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof. The disclosure also relates to methods of reducing acetaminophen-induced liver toxicity in a subject by administering or co-administering one or more of S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof, with acetaminophen to a subject.
Type:
Grant
Filed:
September 16, 2010
Date of Patent:
April 1, 2014
Assignees:
The Board of Trustees of The University of Illinois, The Board of Trustees of The Leland Stanford Junior University
Inventors:
Hong-Hsing Liu, Gary Allen Peltz, Guochun Liao, Timothy Alan Garrow
Abstract: This invention is to provide a method for the production of diamond at a high rate and in a high efficiency using in-liquid plasma. The present invention is a method for the production of diamond using electromagnetic waves irradiated to a liquid containing carbon, hydrogen and oxygen in which the ratio of hydrogen atoms to the sum of carbon atoms and hydrogen atoms is from 0.75 to 0.82 and the ratio of carbon atoms to the sum of carbon atoms and oxygen atoms is from 0.47 to 0.58 so as to generate plasma in the liquid.
Type:
Grant
Filed:
February 7, 2008
Date of Patent:
April 1, 2014
Assignees:
Kabushiki Kaisya Toyota Jidosyokki, Ehime University
Abstract: A platform is proposed for automated analysis of retinal images, for obtaining from them information characterizing retinal blood vessels which may be useful in forming a diagnosis of a medical condition. A first aspect of the invention proposes that a plurality of characteristics of the retina are extracted, in order to provide data which is useful for enabling an evaluation of cardiovascular risk prediction, or even diagnosis of a cardiovascular condition. A second aspect uses fractal analysis of retinal images to provide vascular disease risk prediction, such as, but not limited to, diabetes and hypertension.
Abstract: A double-metallic deposition process is used whereby adjacent layers of different metals are deposited on a substrate. The surface plasmon frequency of a base layer of a first metal is tuned by the surface plasmon frequency of a second layer of a second metal formed thereon. The amount of tuning is dependent upon the thickness of the metallic layers, and thus tuning can be achieved by varying the thicknesses of one or both of the metallic layers. In a preferred embodiment directed to enhanced LED technology in the green spectrum regime, a double-metallic Au/Ag layer comprising a base layer of gold (Au) followed by a second layer of silver (Ag) formed thereon is deposited on top of InGaN/GaN quantum wells (QWs) on a sapphire/GaN substrate.
Type:
Grant
Filed:
December 8, 2010
Date of Patent:
April 1, 2014
Assignee:
Lehigh University
Inventors:
Nelson Tansu, Hongping Zhao, Jing Zhang, Guangyu Liu
Abstract: A method of making a supported gas separation molecular sieve membrane. In this method a porous support, which is preferably pretreated, is contacted with a molecular sieve synthesis mixture under hydrothermal synthesis conditions. The contacting step is conducted for a shortened crystallization time period. The resulting coated porous support is calcined to yield the supported gas separation molecular sieve membrane having particularly good gas separation characteristics.
Type:
Grant
Filed:
May 15, 2009
Date of Patent:
April 1, 2014
Assignees:
Shell Oil Company, The Regents of the University of Colorado, a Body Corporate
Inventors:
Moises Abraham Carreon, Zaida Diaz, John Lucien Falconer, Hans Heinrich Funke, Shiguang Li, Brendan Dermot Murray, Richard Daniel Noble, Paul Jason Williams
Abstract: The present invention relates to methods for purifying immunogenic, prophylactically and therapeutically effective complexes of modified heat shock proteins noncovalently associated with antigenic peptides of cancer or infected cells. The claimed methods comprise the constructing of a nucleotide sequence encoding a secretable modified heat shock protein, expressing the sequence in an appropriate host cell, recovering the immunogenic complexes from the cell culture and the cells, and purifying the immunogenic complexes by affinity chromatography. Large amounts of such immunogenic complexes can be obtained by large-scale culturing of host cells containing the genetic sequence. The complexes can be used as a vaccine to elicit specific immune responses against cancer or infected cells, and to treat or prevent cancer or infectious diseases.
Type:
Grant
Filed:
July 24, 2007
Date of Patent:
April 1, 2014
Assignee:
University of Miami
Inventors:
Eckhard R. Podack, Julie Spielman, Koichi Yamazaki
Abstract: The present invention relates to the isolation and characterization of a protein responsible for the reduction of uranium (VI) to uranium (IV). The present invention extends to the use of the isolated protein in the reduction of uranium (VI) to uranium (IV) and further extends to a process for the bioremediation, or at least partial remediation, of a site contaminated with a source of U (VI). According to a first aspect thereof, the present invention provides an isolated polypeptide derived from Thermus scotoductus strain SA-01 that is responsible for the reduction of uranium (VI), in a source of uranium (VI), to uranium (IV), wherein the polypeptide comprises the amino acid sequence of SEQ ID No: 1.
Type:
Grant
Filed:
September 21, 2010
Date of Patent:
April 1, 2014
Assignee:
University of the Free State
Inventors:
Errol Duncan Cason, Esta Van Heerden, Lizelle Ann Piater, Abitha Gyanendra Jugdave, Jacqueline Van Marwijk
Abstract: The present invention discloses a grain germinating system comprising a temperature controlling device, an incubation device, a drying device and a monitoring device. The temperature controlling device comprises a heat pump module, an air conditioning module and a piping module. The heat pump module can output a high or low temperature heat exchanging liquid. The temperature of a culture medium of a grain is adjusted by the incubation device. The incubated grain is dried by the drying device. The air conditioning module is for a plant building. The piping module is connected with the heat pump module, and is provided for the high or low temperature heat exchanging liquid to flow. The incubation device and the drying device are heated by the high temperature heat exchanging liquid. The drying device is cooled by the low temperature heat exchanging liquid provided for the air condition of the plant building to use.
Type:
Grant
Filed:
March 22, 2010
Date of Patent:
April 1, 2014
Assignee:
Taipei Medical University
Inventors:
Chun-Mao Lin, Fu-Der Mai, Chien-Lung Hung, Chwen-Ming Shih
Abstract: Genetic constructs that comprise a coding sequence for HIV-1 Rev, and a coding sequence for a desired protein are disclosed. Compositions that comprise at least two nucleic acid molecules in which at least one nucleic acid molecule comprises a coding sequence for HIV-1 Rev, and at least one nucleic acid molecule comprises a coding sequence for a desired protein are disclosed. In such genetic constructs and compositions comprising nucleic acid molecules, the coding sequence for the desired protein comprises at least a portion of coding sequence for an HIV structural protein that includes an RRE and at least one CTE. Methods of inducing an immune response against an immunogen in an individual, methods of delivering proteins to an individual and methods of producing proteins are also disclosed.
Type:
Grant
Filed:
November 20, 2008
Date of Patent:
April 1, 2014
Assignee:
The Trustees of the University of Pennsylvania
Abstract: A bond type flip-chip light-emitting structure and method of manufacturing the same. Firstly, form a positive electrode and a negative electrode on an epitaxy layer. Next, deposit an insulation layer on parts of the positive electrode and negative electrode, to expose respectively a positive electrode via hole and a negative electrode via hole. Then, form a bonded metal layer on the insulation layer, the positive electrode via hole, and the negative electrode via hole, so that the positive electrode and the negative electrode are on a same plane by means of the bonded metal layer. Finally, on a substrate, bond the first metal layer and the second metal layer onto the corresponding first bonded metal unit and the second bonded metal unit of the bonded metal layer, to form into shape, thus realizing a bond type flip-chip light-emitting structure.
Abstract: Disclosed herein is a method for separating an arsenic mineral from a copper-bearing material, including the steps of grinding a copper-bearing material containing arsenic, adding water to the copper-bearing material to prepare a slurry, and adding a flotation agent including a depressant, a frother, and a collector to the slurry and blowing air into the slurry for performing flotation to obtain a copper concentrate, wherein the depressant is a chelator. As the chelator, a polyethyleneamine or the like is used. Particularly, when triethylenetetramine is used as the chelator, the amount of triethylenetetramine to be added is preferably 1 to 10 equivalents relative to the amount of soluble copper generated by oxidation of the copper-bearing material, and the pH of the slurry is more preferably adjusted to 7 or more but 8 or less before the slurry is subjected to the flotation.
Type:
Grant
Filed:
February 3, 2011
Date of Patent:
April 1, 2014
Assignees:
Sumitomo Metal Mining Co., Ltd., Kyushu University, National University Corporation