Abstract: New benzoheterocyclic oxadiazolones and triazolones are described. These compounds are useful as anti-allergic reagents.

Abstract: Compounds of the formula ##STR1## wherein R is lower alkyl, phenyl, lower alkenyl, cycloalkyl and substituted phenyl;R.sub.1 is hydrogen, lower alkyl, lower alkenyl, lower alkoxy, amino, lower alkylamino, hydroxy, halo, nitro, mercapto, trifluoromethyl, lower alkylmercapto, and trifluoromethylmercapto;R.sub.2, R.sub.3 are lower alkyl or taken together with N form a cyclic amine;X is O or S, andn is an integer from 2 to 4are useful in treatment of arrhythmia.

Abstract: Antihypertensive compounds of the formula ##STR1## wherein R.sub.5 is H, alkyl, aryl, halo, lower alkoxy, nitro amino, alkylmercapto, cyano, carboxy, carbalkoxy, sulfamyl, trifluoromethyl, hydroxy, acyloxy, methanesulfonyl, alkylamino or acylamino; and each R.sub.1 and R.sub.2 is alkyl; wherein the alkyl, alkoxy and aryl groups contain up to 10 carbon atoms and non-toxic, pharmaceutically-acceptable acid addition salts thereof.

Abstract: Compounds of the formula ##STR1## wherein: Ar and Ar' are independently alicyclic aryl or heterocyclic aryl groups;R.sub.1 is a substituent replacing a hydrogen on the ring and is independently hydroxy, alkyl, alkoxy, halogen, nitro, amino, monoalkyl-amino, dialkyl-amino, sulfhydryl, alkylmercapto, sulfonamido, carboxy, carbalkoxy, or trihalomethyl;n is an integer from 0 to 5 inclusive;R.sub.2 and R.sub.3 are independently hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, phenyl, or cycloalkyl-alkyl; andR.sub.4 and R.sub.5 are independently halogen or trihalomethyl, with the proviso that when both Ar and Ar' are phenyl and n is 0, both R.sub.2 and R.sub.3 are not hydrogen.

Abstract: Compounds of the structure: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, and R.sub.6 are hydrogen, alkyl, alkenyl, alkynyl, phenyl-alkyl, or cycloalkyl,n is an integer from 0 to 4 inclusive,M is alkenyl, alkynyl, cycloalkyl, cycloalkyl-alkyl, polycycloalkyl, polycyclo-alkyl-alkyl, aryl, aralkyl, heteroaryl, heteroaryl-alkyl, hetero-cycloalkyl, hetero-cycloalkyl-alkyl, alkoxyalkyl, alkylthioalkyl, alkylamino-alkyl, dialkylamino-alkyl, fused aryl-cycloalkyl, fused aryl-cycloalkyl-alkyl, fused heteroaryl-cycloalkyl, or fused heteroaryl-cycloalkyl-alkyl,Y is hydroxy, alkoxy, amino, or substituted amino, aminoalkanoyl, aryloxy, aminoalkoxy, or hydroxyalkoxy, andR.sub.7 is hydrogen, alkanoyl, carboxylalkanoyl, hydroxyalkanoyl, amino-alkanoyl, cyano, amidino, carbalkoxy, ZS, or ##STR2## wherein Z is hydrogen, alkyl, hyroxyalkyl, aminoalkyl or the radical ##STR3## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.

Abstract: New pyridothienotriazines are described. These compounds are useful as anti-allergic reagents.

Abstract: Nylidrin administered to institutionalized patients who are over 65 years of age and demonstrate a mild to moderate severity in cognitive, emotional and physical symptoms of the SCAG rating, produced significant improvement.

Abstract: The symptoms of asthma are relieved by the administration of p-hydroxy-N-(1-methyl-3-phenylpropyl)-norephedrine.

Abstract: Compounds of the structure ##STR1## wherein R is lower alkyl or ##STR2## WHEREIN R.sub.1 and R.sub.2 are hydrogen, lower alkyl, lower alkoxy, hydroxy, amino, nitro, halogen and trifluoromethyl and may be the same or different, and m and n are integers from 0 to 1 have potent hypotensive activity.