Patents Assigned to UWM Research Foundation, Inc.
  • Patent number: 10684249
    Abstract: A device for measuring pH levels and contaminant concentration includes an electrode assembly that is electrically coupled to a control unit. The electrode assembly includes a first contact electrically coupled to a reference electrode, a second contact electrically coupled to a working electrode, and a third contact electrically coupled to a counter electrode. The working electrode may be modified to include a cysteine functionalized graphene oxide with polypyrrole nanocomposite. In operation, the control unit may apply a complex signal to the working electrode via the second contact in order to adhere and subsequently strip contaminant ions from the fluid sample to the working electrode. During this process, a current may be measured across the working electrode and the counter electrode to measure contaminant ion concentration. The pH of the fluid sample may also be determined by a current measured across the reference electrode and the counter electrode.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: June 16, 2020
    Assignee: UWM Research Foundation, Inc.
    Inventors: Sundaram Gunasekaran, Woo-Jin Chang, Jiang Yang, Rajesh Seenivasan
  • Patent number: 10625110
    Abstract: A garment including a garment body configured to be wearable by a person. The garment also includes a first tube selectively coupled to the garment body. The first tube is configured to receive a first desired amount of liquid through a first opening of the first tube. The garment further includes a second tube selectively coupled to the garment body independently of the first tube. The second tube is configured to receive a second desired amount of liquid through a second opening of the second tube. The second tube is fluidly distinct from the first tube.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: April 21, 2020
    Assignee: UWM Research Foundation, Inc.
    Inventor: Chad Henneberry
  • Patent number: 10404098
    Abstract: A battery management system for monitoring battery cells of an uninterruptible power supply (UPS) coupled to a medical imaging load. The battery management system includes a first slave configured to obtain an operating parameter of a first battery cell. The first slave is configured to determine health of the first battery cell based at least in part on the operating parameter. The first slave is configured to generate a signal indicating the health of the first battery cell to communicate serially, via at least a second slave, to a master.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: September 3, 2019
    Assignees: UWM RESEARCH FOUNDATION INC., GENERAL ELECTRIC COMPANY
    Inventors: Adel Nasiri, Seyed Ahmad Hamidi, Russell Wayne Hum, John Ferdinand Bopp
  • Patent number: 10381641
    Abstract: The present disclosure relates generally to the field of lithium-ion batteries and battery modules. More specifically, the present disclosure relates to Si-based anode materials for use as anode active materials for lithium-ion batteries. One example includes micron/nano-scale structures that include a carbonate template structure and a silicon (Si) layer conformally deposited over the carbonate template. Another example includes a hollow, micron/nano-scale silicon structure having an oxygen content less than approximately 9%, wherein the interior of the hollow micron/nano-scale silicon structure is substantially free of carbon.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: August 13, 2019
    Assignee: UWM RESEARCH FOUNDATION, INC.
    Inventors: Junhong Chen, Xingkang Huang
  • Patent number: 10281464
    Abstract: Provided herein is a field-effect transistor based sensor for real-time detection of water contaminants and methods of use thereof.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: May 7, 2019
    Assignee: UWM Research Foundation, Inc.
    Inventors: Junhong Chen, Jingbo Chang
  • Patent number: 10259815
    Abstract: Described herein are ?3 or ?2 or ?2/?3 GABAergic receptor subtype selective ligands, pharmaceutical compositions, and methods of use of such ligands and compositions in treatment of anxiety disorders, epilepsy and schizophrenia with reduced sedative and ataxic side effects. In embodiments, such as ?3 or ?2 or ?2/?3 GABAergic receptor subtype selective ligands lack ester linkages and may be thus relatively insensitive to hydrolysis by esterases.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: April 16, 2019
    Assignee: UWM Research Foundation, Inc.
    Inventors: James Cook, Michael Ming-Jin Poe, Kashi Reddy Methuku, Guanguan Li
  • Patent number: 10128510
    Abstract: Provided are nanocomposites including an iron-based core and a nitrogen-doped graphitic carbon shell, and methods of making and using the same. Included in the nanocomposites is an Fe3C-based interlayer between the core and the shell. The nanocomposites can show a catalytic activity toward reducing oxygen comparable to commercial Pt/C catalysts.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: November 13, 2018
    Assignee: UWM Research Foundation, Inc.
    Inventors: Junhong Chen, Zhenhai Wen
  • Patent number: 10093653
    Abstract: Described herein are compounds, pharmaceutical compositions and methods for inhibiting the expression of a vitamin D receptor target gene, inhibiting interactions between the vitamin D receptor and at least one vitamin D receptor coactivator, for treating cancer in a subject, and for inhibiting angiogenesis in a subject.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: October 9, 2018
    Assignees: UWM Research Foundation, Inc., Women and Infants Hospital of Rhode Island
    Inventors: Alexander E. Arnold, Preetpal Singh Sidhu, Premchendar Nandhikonda, Rakesh K. Singh
  • Patent number: 10071015
    Abstract: A method increases a tactile sensitivity of a fingertip of a user with a wearable device. The wearable device includes a vibrating element, an actuator for receiving user input, and a control circuitry. The method includes positioning the vibrating element on one of a user's arm, wrist, hand, or proximal finger segment and activating the vibrating element to apply a vibrating force at a first magnitude. The method also includes receiving user input indicating that the user detected movement of the vibrating element at the first magnitude and applying the vibrating force at a second magnitude, the second magnitude being lower than the first magnitude, to increase the tactile sensitivity of at least one fingertip of the user.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: September 11, 2018
    Assignee: UWM Research Foundation, Inc.
    Inventors: Na Jin Seo, Leah R. Enders
  • Patent number: 9879020
    Abstract: Novel methods of treating inflammation and airway constriction using GABAergic compounds with reduced benzo-diazepine-like CNS activity are provided. Novel compounds which selectively target alpha-4 and alpha-5 GABAA receptors and methods of using those compounds to treat bronchoconstriction and inflammation are provided herein.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: January 30, 2018
    Assignees: UWM Research Foundation, Inc., The Trustees of Columbia University in the City of New York
    Inventors: Douglas C. Stafford, James M. Cook, Alexander E. Arnold, Charles W. Emala, George Gallos, Michael Rajesh Stephen
  • Patent number: 9867480
    Abstract: An infant sleep pod providing passive and/or active safety features. The infant sleep pod provides a safe sleeping environment for infants sharing sleep areas with adults. The infant sleep pod provides a firm, flat, separate, portable, and dedicated sleep space for an infant. The infant sleep pod includes a base with a bed and sidewall, and a bridge extending across the bed. The bridge covers a head portion of the bed, while a foot portion of the bed is left open for inserting and removing the infant. The bridge prevents pillows and blankets from covering the bed and infant. The infant sleep pod also includes electronics for monitoring the sleep pod. The electronics include a sensor unit in the bridge and a control unit in communication with the sensor unit. The control unit and sensor unit are operable to detect unsafe conditions and, in response, generate alerts.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: January 16, 2018
    Assignee: UWM Research Foundation, Inc.
    Inventors: Jennifer J. Doering, Greg Krzecki
  • Patent number: 9867549
    Abstract: This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P).
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: January 16, 2018
    Assignees: The Queen's Medical Center, The University of Hawaii, The Medical College of Wisconsin, Inc., UWM Research Foundation, Inc.
    Inventors: Thomas Michael Ernst, Thomas Edmund Prieto, Brian Stewart Randall Armstrong
  • Patent number: 9709526
    Abstract: A method of characterizing proteins has been developed that includes providing a sample that contains a plurality of proteins to be characterized, wherein at least a first protein of the plurality of proteins is in its native form. Additionally, the method includes contacting the sample containing the plurality of proteins with a solution to form a sample solution, and then contacting the sample solution with a gel. The plurality of proteins is subsequently separated via electrophoresis within the gel, which includes an electrophoresis solution.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: July 18, 2017
    Assignee: UWM Research Foundation, Inc.
    Inventors: David H. Petering, William J. Wobig, Andrew Nowakowski
  • Patent number: 9676621
    Abstract: The disclosure provides a field-effect transistor (FET)-based biosensor and uses thereof. In particular, to FET-based biosensors using thermally reduced graphene-based sheets as a conducting channel decorated with nanoparticle-biomolecule conjugates. The present disclosure also relates to FET-based biosensors using metal nitride/graphene hybrid sheets. The disclosure provides a method for detecting a target biomolecule in a sample using the FET-based biosensor described herein.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: June 13, 2017
    Assignee: UWM Research Foundation, Inc.
    Inventors: Junhong Chen, Shun Mao, Ganhua Lu
  • Patent number: 9597342
    Abstract: Described herein are ?3 or ?2 or ?2/?3 GABAergic receptor subtype selective ligands, pharmaceutical compositions, and methods of use of such ligands and compositions in treatment of anxiety disorders, epilepsy and schizophrenia with reduced sedative and ataxic side effects. In embodiments, such as ?3 or ?2 or ?2/?3 GABAergic receptor subtype selective ligands lack ester linkages and may be thus relatively insensitive to hydrolysis by esterases.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: March 21, 2017
    Assignee: UWM Research Foundation, Inc.
    Inventors: James M. Cook, Terry S. Clayton, Hiteshkumar D. Jain, Yun Teng Johnson, Jie Yang, Sundari K. Rallipalli, Zhi-jian Wang, Ojas A. Namjoshi, Michael Ming-Jin Poe
  • Patent number: 9599683
    Abstract: A camera assembly for use in a MRI machine. The camera assembly includes a Faraday cage defining a shielded cavity and an optical path mount constructed of a highly stiff, dense, and non-electrically-conductive material in the shielded cavity. The camera imager and lens are mounted to the optical path mount. The camera assembly includes a capacitor-based power regulation circuit. The optical path mount is not subject to eddy currents because it is non-electrically-conductive. The capacitor-based power regulation circuit includes very little ferrous material and is within the shielded cavity, to reduce eddy currents. The resulting camera assembly reduces vibrations and shaking in the magnetic field environment of the MRI machine.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: March 21, 2017
    Assignee: UWM Research Foundation, Inc.
    Inventors: Brian S. R. Armstrong, Todd P. Kusik, Robert T. Barrows
  • Patent number: 9554659
    Abstract: An infant sleep pod providing passive and/or active safety features. The infant sleep pod provides a safe sleeping environment for infants sharing sleep areas with adults. The infant sleep pod provides a firm, flat, separate, portable, and dedicated sleep space for an infant. The infant sleep pod includes a base with a bed and sidewall, and a bridge extending across the bed. The bridge covers a head portion of the bed, while a foot portion of the bed is left open for inserting and removing the infant. The bridge prevents pillows and blankets from covering the bed and infant. The infant sleep pod also includes electronics for monitoring the sleep pod. The electronics include a sensor unit in the bridge and a control unit in communication with the sensor unit. The control unit and sensor unit are operable to detect unsafe conditions and, in response, generate alerts.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: January 31, 2017
    Assignee: UWM Research Foundation, Inc.
    Inventors: Jennifer J. Doering, Greg Krzecki
  • Patent number: 9527038
    Abstract: A bioelectrochemical system includes an anode, a saline solution chamber, and a cathode. The anode is at least partially positioned within an anode chamber containing an aqueous reaction mixture including one or more organic compounds and one or more bacteria for oxidizing the organic compounds. The saline solution chamber contains a draw solution and is separated from the anode chamber by a forward osmosis membrane. Water diffuses across the forward osmosis membrane from the aqueous reaction mixture to the draw solution.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: December 27, 2016
    Assignee: UWM Research Foundation, Inc.
    Inventor: Zhen He
  • Patent number: 9464064
    Abstract: The present invention discloses thioflavine S and primuline derivatives which inhibit hepatitis C virus helicase and protease activity. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are useful as antiviral agents. The present invention further relates to pharmaceutical compositions containing the aforementioned compounds and methods of treating an HCV infection.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: October 11, 2016
    Assignees: University of Kansas, UWM Research Foundation, Inc.
    Inventors: Jeffrey Aube, Brian Scott Jonathan Blagg, Kevin John Frankowski, David Norman Frick, Kelin Li, Frank John Schoenen
  • Patent number: 9416104
    Abstract: Described herein are compounds, pharmaceutical compositions and methods for inhibiting the expression of a vitamin D receptor target gene, inhibiting interactions between the vitamin D receptor and at least one vitamin D receptor coactivator, for treating cancer in a subject, and for inhibiting angiogenesis in a subject.
    Type: Grant
    Filed: August 26, 2012
    Date of Patent: August 16, 2016
    Assignees: UWM Research Foundation, Inc., Women and Infants' Hospital of Rhode Island
    Inventors: Alexander E. Arnold, Preetpal Singh Sidhu, Premchendar Nandhikonda, Rakesh K. Singh