Patents Assigned to Valneva SE
  • SUBUNIT VACCINE FOR TREATMENT OR PREVENTION OF A RESPIRATORY TRACT INFECTION
    Publication number: 20240067681
    Abstract: The present invention relates to modified hMPV F proteins stabilized in the pre-fusion conformation as vaccine candidates.
    Type: Application
    Filed: October 24, 2023
    Publication date: February 29, 2024
    Applicant: Valneva SE
    Inventors: Fabien Perugi, Klaus Schwamborn, Wolfgang Schüler, Urban Lundberg, Andreas Meinke
  • METHOD OF PRODUCING PHARMACEUTICAL COMPOSITIONS COMPRISING IMMUNOGENIC CHIKUNGUNYA VIRUS CHIKV-DELTA5NP3
    Publication number: 20230293661
    Abstract: The present invention relates to a process for producing an immunogenic live attenuated Chikungunya virus, as well as pharmaceutical compositions comprising the same.
    Type: Application
    Filed: September 26, 2022
    Publication date: September 21, 2023
    Applicant: Valneva SE
    Inventors: Andrea Fritzer, Andreas Meinke, Urban Lundberg, Mario Nebenfuhr, Jurgen Heindl-Wruss, Robert Schlegl, Arnaud Leon
  • Aseptic purification process for viruses
    Patent number: 11629339
    Abstract: Described herein are processes for the purification of viruses and compositions thereof.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: April 18, 2023
    Assignee: Valneva SE
    Inventors: Robert Schlegl, Michael Weber
  • VIRUS PURIFICATION
    Publication number: 20230056142
    Abstract: Described herein are processes for purifying infectious virus particles and uses of protamine in such processes.
    Type: Application
    Filed: July 6, 2022
    Publication date: February 23, 2023
    Applicant: VALNEVA SE
    Inventors: Jana BARBERO CALZADO, Mario NEBENFÜHR, Robert SCHLEGL, Michael WEBER, Jürgen HEINDL-WRUSS
  • Method of producing pharmaceutical compositions comprising immunogenic Chikungunya virus CHIKV-Delta5nsP3
    Patent number: 11484587
    Abstract: The present invention relates to a process for producing an immunogenic live attenuated Chikungunya virus, as well as pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: November 1, 2022
    Assignee: Valneva SE
    Inventors: Andrea Fritzer, Andreas Meinke, Urban Lunberg, Mario Nebenfuhr, Jurgen Heindl-Wruss, Robert Schlegl, Arnaud Leon
  • SINGLE SHOT CHIKUNGUNYA VIRUS VACCINE
    Publication number: 20220313810
    Abstract: The present invention relates to a single-shot live attenuated vaccine against Chikungunya virus which is well-tolerated and induces long-lasting protective immunity in adult human subjects.
    Type: Application
    Filed: August 10, 2020
    Publication date: October 6, 2022
    Applicant: Valneva SE
    Inventors: Nina Wressnigg, Romana Hochreiter
  • CHIKUNGUNYA VACCINE FORMULATIONS
    Publication number: 20220288185
    Abstract: The present invention is related to novel liquid and lyophilized formulations of Chikungunya virus useful as vaccines and methods for their preparation.
    Type: Application
    Filed: August 10, 2020
    Publication date: September 15, 2022
    Applicant: Valneva SE
    Inventors: Christoph Reinisch, Robert Schlegl, Jürgen Heindl-Wruss
  • Virus purification
    Patent number: 11406700
    Abstract: Described herein are processes for purifying infectious virus particles and uses of protamine in such processes.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: August 9, 2022
    Assignee: Valneva SE
    Inventors: Jana Barbero Calzado, Mario Nebenführ, Robert Schiegl, Michael Weber, Jürgen Heindl-Wruss
  • A SUBUNIT VACCINE FOR TREATMENT OR PREVENTION OF A RESPIRATORY TRACT INFECTION
    Publication number: 20220185847
    Abstract: The present invention relates to modified metapneumovirus (hMPV) F proteins, stabilized in the pre-fusion conformation. It also relates to immunogenic compositions (vaccines) comprising these proteins for preventing and/or treating human subjects against respiratory tract infections.
    Type: Application
    Filed: May 19, 2020
    Publication date: June 16, 2022
    Applicant: Valneva SE
    Inventors: Fabien Perugi, Klaus Schwamborn, Wolfgang Schüler, Urban Lundberg, Andreas Meinke
  • Method of producing pharmaceutical compositions comprising immunogenic chikungunya virus CHIKV-Delta5NP3
    Patent number: 11357846
    Abstract: The present invention relates to a process for producing an immunogenic live attenuated Chikungunya virus, as well as pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: August 20, 2021
    Date of Patent: June 14, 2022
    Assignee: Valneva SE
    Inventors: Andrea Fritzer, Andreas Meinke, Urban Lundberg, Mario Nebenführ, Jürgen Heindl-Wruss, Robert Schiegl, Arnaud Leon
  • METHOD OF PRODUCING PHARMACEUTICAL COMPOSITIONS COMPRISING IMMUNOGENIC CHIKUNGUNYA VIRUS CHIKV-DELTA5NP3
    Publication number: 20220016230
    Abstract: The present invention relates to a process for producing an immunogenic live attenuated Chikungunya virus, as well as pharmaceutical compositions comprising the same.
    Type: Application
    Filed: August 20, 2021
    Publication date: January 20, 2022
    Applicant: Valneva SE
    Inventors: Andrea Fritzer, Andreas Meinke, Urban Lundberg, Mario Nebenführ, Jürgen Heindl-Wruss, Robert Schlegl, Arnaud Leon
  • Virus purification
    Patent number: 11207397
    Abstract: Described herein are improved purification methods for virus vaccines and compositions. Also described are Zika, Chikungunya, dengue and yellow fever vaccines and methods of producing and administering said vaccines to subjects in need thereof.
    Type: Grant
    Filed: December 4, 2019
    Date of Patent: December 28, 2021
    Assignee: Valneva SE
    Inventors: Jana Barbero Calzado, Mario Nebenführ, Robert Schiegl, Michael Weber, Jürgen Heindl-Wruss
  • METHOD FOR RESCUING AND PRODUCING A VIRUS IN AVIAN CELLS
    Publication number: 20210275662
    Abstract: The present invention relates to methods of rescue and/or propagation of paramyxovirus species, particularly wherein both rescue and propagation are carried out in the same cell type; i.e., without the use of helper cells for viral rescue. The paramyxoviruses produced by the disclosed methods may encompass wild-type viruses, chimeric viruses, recombinant viruses or engineered viral products such as virus like particles (VLP). Viruses and/or viral products produced in the method according to the current invention are suitable for medical or veterinary use in such applications as treating or preventing infectious diseases, particularly avian paramyxovirus and human respiratory virus infections, and cancer treatment.
    Type: Application
    Filed: July 15, 2019
    Publication date: September 9, 2021
    Applicant: Valneva SE
    Inventors: Luc Batard, Caroline Freslon-Evain, Fabien Perugi, Klaus Schwamborn
  • VIRUS PURIFICATION
    Publication number: 20200368342
    Abstract: Described herein are processes for purifying infectious virus particles and uses of protamine in such processes.
    Type: Application
    Filed: April 6, 2020
    Publication date: November 26, 2020
    Applicant: Valneva SE
    Inventors: Jana Barbero Calzado, Mario Nebenführ, Robert Schlegl, Michael Weber, Jürgen Heindl-Wruss
  • ASEPTIC PURIFICATION PROCESS FOR VIRUSES
    Publication number: 20200347364
    Abstract: Described herein are processes for the purification of viruses and compositions thereof.
    Type: Application
    Filed: March 11, 2020
    Publication date: November 5, 2020
    Applicant: Valneva SE
    Inventors: Robert Schlegl, Michael Weber
  • VIRUS PURIFICATION
    Publication number: 20200197506
    Abstract: Described herein are improved purification methods for virus vaccines and compositions. Also described are Zika, Chikungunya, dengue and yellow fever vaccines and methods of producing and administering said vaccines to subjects in need thereof.
    Type: Application
    Filed: December 4, 2019
    Publication date: June 25, 2020
    Applicant: Valneva SE
    Inventors: Jana Barbero Calzado, Mario Nebenführ, Robert Schlegl, Michael Weber, Jürgen Heindl-Wruss
  • Virus purification
    Patent number: 10660950
    Abstract: Described herein are processes for purifying infectious virus particles and uses of protamine in such processes.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: May 26, 2020
    Assignee: Valneva SE
    Inventors: Jana Barbero Calzado, Mario Nebenführ, Robert Schlegl, Michael Weber, Jürgen Heindl-Wruss
  • Aseptic purification process for viruses
    Patent number: 10662412
    Abstract: Described herein are processes for the purification of viruses and compositions thereof.
    Type: Grant
    Filed: April 4, 2016
    Date of Patent: May 26, 2020
    Assignee: Valneva SE
    Inventors: Robert Schlegl, Michael Weber
  • Virus purification
    Patent number: 10537630
    Abstract: Described herein are improved purification methods for virus vaccines and compositions. Also described are Zika, Chikungunya, dengue and yellow fever vaccines and methods of producing and administering said vaccines to subjects in need thereof.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: January 21, 2020
    Assignee: Valneva SE
    Inventors: Jana Barbero Calzado, Mario Nebenführ, Robert Schlegl, Michael Weber, Jürgen Heindl-Wruss
  • VIRUS PURIFICATION
    Publication number: 20180369359
    Abstract: Described herein are improved purification methods for virus vaccines and compositions. Also described are Zika, Chikungunya, dengue and yellow fever vaccines and methods of producing and administering said vaccines to subjects in need thereof.
    Type: Application
    Filed: December 23, 2016
    Publication date: December 27, 2018
    Applicant: Valneva SE
    Inventors: Jana Barbero Calzado, Mario Nebenführ, Robert Schlegl, Michael Weber, Jürgen Wruss