Patents Assigned to Virginia Tech
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Patent number: 10067130Abstract: The present invention also provides infectious DNA clones, biologically functional plasmid or viral vector containing the infectious nucleic acid genome molecule of Torque teno sus virus (TTsuV). The present invention also provides methods for diagnosing TTsuV infection via immunological methods, e.g., enzyme-linked immunoabsorbent assay (ELISA) and Western blot using PTTV specific antigens for detecting serum PTTV specific antibodies which indicate infections TTsuV1, TTsuV2, and individual TTsuV1 genotypes.Type: GrantFiled: December 22, 2015Date of Patent: September 4, 2018Assignee: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.Inventors: Xiang-Jin Meng, Yaowei Huang
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Patent number: 10048222Abstract: The present invention provides an ionization detector having a base having an enclosed chamber. The enclosed chamber has a first end and a second end. The detector also includes a first outlet which is a source of an excitable medium. A second outlet is provided which functions a source of an analyte that is transported by a carrier gas. An ionization source for creating a discharge from said excitable medium is also provided. The collector electrode generates a time dependent current based on its interaction with ionized analytes from which the analyte may be detected.Type: GrantFiled: October 31, 2014Date of Patent: August 14, 2018Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: Masoud Agah, Shree Narayanan Sreedharan Nair
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Patent number: 10038460Abstract: Embodiments of the present disclosure describe methods, apparatuses, and systems related to a wireless communication device using time-variant antenna. Other embodiments may be described and/or claimed.Type: GrantFiled: November 2, 2016Date of Patent: July 31, 2018Assignees: INTEL CORPORATION, VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.Inventors: Seong-Youp Suh, W. Dawson Kesling, Majid Manteghi, Mohsen Salehi, Harry Skinner
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Patent number: 10032732Abstract: In a switching module structure that includes a low-impedance path to ground, such as a parasitic capacitance of an insulating substrate, a further insulating substrate presenting a parasitic capacitance placed in series with the low impedance current path and a connection of a conductive layer to input voltage rails using a single decoupling capacitor or, preferably, a midpoint of the voltage rails formed by a series connection of decoupling capacitors maintains a large portion of common mode (CM) currents which are due to high dV/dt slew rates of SiC and GaN transistors within the switching module.Type: GrantFiled: May 3, 2017Date of Patent: July 24, 2018Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: Christina DiMarino, Dushan Boroyevich, Rolando Burgos, Mark Johnson
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Patent number: 10013007Abstract: In a multi-phase power converter using a phase-locked loop (PLL) arrangement for interleaving of pulse frequency modulated (PFM) pulses of the respective phases, improved transient response, improved stability of high bandwidth output voltage feedback loop, guaranteed stability of the PLL loop and avoidance of jittering and phase cancellation issues are achieved by anchoring the bandwidth at the frequency of peak phase margin. This methodology is applicable to multi-phase power conveners of any number of phases and any known or foreseeable topology for individual phases and is not only applicable to power converters operating under constant on-time control, but is extendable to ramp pulse modulation (RPM) control and hysteresis control. Interleaving of pulses from all phases is simplified through use of phase managers with a reduced number of PLLS using hybrid interleaving arrangements that do not exhibit jittering even when ripple is completely canceled.Type: GrantFiled: March 31, 2015Date of Patent: July 3, 2018Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: Pei-Hsin Liu, Qiang Li, Fred C. Lee
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Patent number: 9998111Abstract: Capacitors connected between gate terminals of a plurality of parallel-connected power transistors are charged and discharged in each switching cycle to provide a plurality of power transistor control waveforms from a single gate driver waveform that equalize power losses/temperatures or steady-state currents among the plurality of power transistors. The capacitors are charged to different voltages by diverting current from one transistor driver by disabling another power transistor driver at different respective times in response to measured transient or steady state current or temperature or other operational parameter.Type: GrantFiled: September 29, 2016Date of Patent: June 12, 2018Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: Khai Ngo, Lujie Zhang, Zichen Miao
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Publication number: 20180147275Abstract: The present invention relates to infectious DNA clones, infectious chimeric DNA clones of porcine circovirus (PCV), vaccines and means of protecting pigs against viral infection or postweaning multisystemic wasting syndrome (PMWS) caused by PCV2. The new chimeric infectious DNA clone and its derived, avirulent chimeric virus are constructed from the nonpathogenic PCV1 in which the immunogenic ORF gene of the pathogenic PCV2 replaces a gene of the nonpathogenic PCV1, preferably in the same position. The chimeric virus advantageously retains the nonpathogenic phenotype of PCV1 but elicits specific immune responses against the pathogenic PCV2. The invention further embraces the immunogenic polypeptide expression products. In addition, the invention encompasses two mutations in the PCV2 immunogenic capsid gene and protein, and the introduction of the ORF2 mutations in the chimeric clones.Type: ApplicationFiled: January 19, 2018Publication date: May 31, 2018Applicants: Virginia Tech Intellectual Properties, Inc., Iowa State University Research Foundation, Inc.Inventors: Xiang-Jin Meng, Martijn Fenaux, Patrick G. Halbur
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Patent number: 9966874Abstract: In a modular multi-level power converter, additional switching states are interleaved between main switching states that control output voltage or waveform. The additional switching states provide current from a DC-link to charge capacitors in respective modules or cells to an offset voltage from which the capacitor voltages are controlled toward a reference voltage during each switching cycle rather than being allowed to build up over a period of an output waveform of variable line frequency, possibly including zero frequency. Since the switching cycle is much shorter than the duration of a line frequency cycle and the capacitor voltages are balanced during each switching cycle, output voltage ripple can be limited as desired with a capacitor of much smaller value and size than would otherwise be required.Type: GrantFiled: December 22, 2014Date of Patent: May 8, 2018Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: Jun Wang, Rolando Burgos, Dushan Boroyevich, Bo Wen
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Publication number: 20180122746Abstract: A power device package includes a dielectric substrate having an upper conductor layer and a lower conductor layer, a semiconductor die coupled to the upper conductor layer of the dielectric substrate via conductive adhesive, a cooler including a protruding hillock having a top surface and outer sides, the lower conductor layer of the dielectric substrate being coupled to the surface of the protruding hillock via an adhesive, and a magnetic material attached mateably around the protruding hillock. The magnetic material includes inner sides abutting the outer sides of the protruding hillock.Type: ApplicationFiled: June 14, 2017Publication date: May 3, 2018Applicants: TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC., VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.Inventors: Khai NGO, Chi-Ming WANG, Han CUI
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Patent number: 9944618Abstract: This document relates to compounds as well as methods and materials involved in modulating neurotransmitter reuptake. For example, compounds, methods for synthesizing compounds, and methods for inhibiting neurotransmitter reuptake are provided. Specifically gamma-amino alcohol derivatives that inhibit the reuptake of neurotransmitters such as dopamine, serotonin, epinephrine or norepinephrine are provided as therapeutic agents for the treatment of depression or anxiety in a mammalian subject.Type: GrantFiled: March 10, 2014Date of Patent: April 17, 2018Assignees: Mayo Foundation for Medical Education and Research, Virginia Tech Intellectual Properties, Inc.Inventors: Elliott Richelson, Abdul H. Fauq, Paul Carlier, Christopher J. Monceaux
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Patent number: 9931784Abstract: The present invention concerns a system and method for fabricating a three-dimensional object. A build platform is provided that defines a build area and includes a print bed within the build area. Also provided is an extruder that extrudes build material. An ejector having at least one arm that has at least two opposing ends is used to remove the printed object. The first end of the ejector is adapted to travel in a vertical direction and the second end is adapted to travel in a horizontal direction. A scraper portion extends horizontally, parallel to the print bed from a retracted position to an extended position when the first end travels in a vertical direction towards the print bed.Type: GrantFiled: May 1, 2015Date of Patent: April 3, 2018Assignee: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.Inventor: Kevin D. Kline
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Patent number: 9923560Abstract: Aspects of the disclosure provide a system having a power circuit. The power circuit includes a first switch circuit having at least a first transistor and a second switch circuit having at least a second transistor. Further, the power circuit includes first interconnections configured to couple the first switch circuit to driving nodes, a source node and a drain node of the power circuit, and second interconnection configured to couple the second switch circuit in parallel to the first switch circuit to the driving nodes, the source node and the drain node of the power circuit. A polarity of unbalance in the first interconnections and the second interconnections dominates a polarity of current unbalance in the first switch circuit and the second switch circuit.Type: GrantFiled: April 13, 2016Date of Patent: March 20, 2018Assignees: Toyota Motor Engineering & Manufacturing North America, Inc., VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.Inventors: Chi-Ming Wang, Yincan Mao, Zichen Miao, Khai Ngo
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Publication number: 20180076915Abstract: The present invention provides a method and system for a processing multicarrier signal to create a spectral correlation across multiple antennas. The system includes at least one transmitter adapted to create a plurality of symbols, each symbol representing one or more bits from a plurality of bitstreams. The transmitter creates a plurality of repetition patterns, each pattern containing a copy of the symbols and each repetition pattern comprising a combination of symbols that varies in time, frequency and space. The repetition patterns are transmitted over and received by one or more separate antennas where a receiver demodulates the repetition patterns and linearly combines each repeated symbols across time, frequency and space to estimate said transmitted symbol.Type: ApplicationFiled: April 7, 2016Publication date: March 15, 2018Applicant: Virginia Tech Intellectual Properties, Inc.Inventors: Matthew Carrick, Jeffrey H. Reed, Vuk Marojevic
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Patent number: 9916416Abstract: A system and method for genotyping tandem repeats in sequencing data. The invention uses Bayesian model selection guided by an empirically-derived error model that incorporates properties of sequence reads and reference sequences to which they map.Type: GrantFiled: October 18, 2013Date of Patent: March 13, 2018Assignee: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.Inventors: David A. Mittelman, Christopher T. Franck
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Patent number: 9914362Abstract: Switches of a switching circuit used to control operation of an electric motor such as in an electrically powered vehicle connect respective windings of the electric motor as a single phase inductor during battery charging. The inductor can then store inherent low frequency, second order ripple power and return that power to a load presented by a battery during battery charging to deliver substantially constant current. Storage of ripple power in the inductor allows the capacitance value, size, weight and cost of a filter capacitor of a power factor correction circuit providing input power to a battery charger to be reduced by an order of magnitude or more. Direction of current flow through the inductor is periodically reversed to avoid magnetizing the motor.Type: GrantFiled: December 23, 2013Date of Patent: March 13, 2018Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: Khai Doan The Ngo, Hui Wang
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Publication number: 20180050487Abstract: A method for manufacturing a three dimensional object includes steps of: providing a digital description of the object as a set of voxels; sequentially creating an actual set of voxels corresponding to the digital set of voxels. At least one voxel comprises a polymer derived from: polyol and an ionic monomer. The calculated charge density of the resulting polymer is 0.01 to 0.7 mEq/g.Type: ApplicationFiled: August 3, 2017Publication date: February 22, 2018Applicant: Virginia Tech Intellectual Properties IncInventors: Travis Kyle Hodgdon, Timothy E. Long, Allison M. Pekkanen, Abby Rebecca Whittington, Christopher Bryant Williams, Callie Elizabeth Zawaski, Douglas M. Graham, Corey J. Kenneally, Freddy Arthur Barnabas
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Publication number: 20180054140Abstract: Aspects of interface converter common mode (CM) voltage control are described. In one embodiment, a bi-directional alternating current (AC) to direct current (DC) interface converter system includes an AC-DC converter between an AC power system and an interface link and a DC-DC converter between a DC power system and the interface link. The AC-DC converter can include a bridge converter having power switches, such as field-insulated gate bipolar transistors (IGBTs) or another power semiconductor device. The system also includes a control loop that generates control signals for switching the power switches of the AC-DC converter, and a CM control loop that injects a CM control signal into the control loop. By injecting the CM control signal into the control loop, low-frequency ripple and asymmetry between positive and negative output voltages of the DC power system can be reduced.Type: ApplicationFiled: August 22, 2016Publication date: February 22, 2018Applicant: Virginia Tech Intellectual Properties, Inc.Inventors: Fang Chen, Rolando Burgos, Dushan Boroyevich
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Patent number: 9897605Abstract: The present invention provides four purified preparation containing a polynucleic acid molecule encoding porcine Torque teno virus (PTTV) genotypes or subtypes PTTV1a-VA, PTTV1b-VA, PTTV2b-VA, and PTTV2c-VA. The present invention also provides infectious DNA clones, biologically functional plasmid or viral vector containing the infectious nucleic acid genome molecule of the same. The present invention further provides live, attenuated, vector-expressed and purified recombinant capsid subunit or killed viral vaccines for protection against PTTV infection. The present invention additionally provides subunit vaccines comprising PTTV specific gene products, especially ORF1 capsid gene product for protection against PTTV infection. Further, the present invention provides methods for diagnosing PTTV infection via polymerase chain reaction (PCR) using specific primer for PTTV1, PTTV2, and individual PTTV1 genotypes.Type: GrantFiled: November 19, 2015Date of Patent: February 20, 2018Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: Xiang-Jin Meng, Yaowei Huang
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Patent number: 9889187Abstract: The present invention relates to infectious DNA clones, infectious chimeric DNA clones of porcine circovirus (PCV), vaccines and means of protecting pigs against viral infection or postweaning multisystemic wasting syndrome (PMWS) caused by PCV2. The new chimeric infectious DNA clone and its derived, avirulent chimeric virus are constructed from the nonpathogenic PCV1 in which the immunogenic ORF gene of the pathogenic PCV2 replaces a gene of the nonpathogenic PCV1, preferably in the same position. The chimeric virus advantageously retains the nonpathogenic phenotype of PCV1 but elicits specific immune responses against the pathogenic PCV2. The invention further embraces the immunogenic polypeptide expression products. In addition, the invention encompasses two mutations in the PCV2 immunogenic capsid gene and protein, and the introduction of the ORF2 mutations in the chimeric clones.Type: GrantFiled: November 13, 2015Date of Patent: February 13, 2018Assignees: Virginia Tech Intellectual Properties, Inc., Iowa State University Foundation, Inc.Inventors: Xiang-Jin Meng, Martijn Fenaux, Patrick G. Halbur
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Patent number: 9888030Abstract: A computer system for distinguishing user-initiated network traffic from malware-initiated network traffic comprising at least one central processing unit (CPU) and a memory communicatively coupled to the CPU. The memory includes a program code executable by the CPU to monitor individual network events to determine for an individual network event whether the event has a legitimate root-trigger. Malware-initiated traffic is identified as an individual network event that does not have a legitimate root-trigger.Type: GrantFiled: May 1, 2014Date of Patent: February 6, 2018Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: Danfeng Yao, Hao Zhang