Abstract: The present invention relates to an anti-CD40 antibody or an antigen-binding fragment thereof that specifically recognizes human, cynomolgus monkey and mouse CD40 molecules and weakly agonizes the CD40 molecules, and an immunoconjugate, a pharmaceutical composition and a combined product containing the anti-CD40 antibody or the antigen-binding fragment thereof. The present invention also relates to a nucleic acid encoding the anti-CD40 antibody or the antigen-binding fragment thereof, a host cell containing the nucleic acid, and a method for preparing the anti-CD40 antibody or the antigen-binding fragment thereof. The present invention further relates to the use of the anti-CD40 antibody or the antigen-binding fragment thereof in the prevention or treatment of tumors or infectious diseases in a subject.

Abstract: A camera device includes an image sensor configured to capture an image, an object identifier configured to identify an object included in the captured image, a distance measurement device configured to determine a distance between the camera device and the identified object based on an occupancy percentage of the identified object in the captured image, and a controller configured to determine an optimal focus location where a reference value is the largest while moving a lens in a focus range corresponding to the determined distance between the camera device and the identified object, the focus range including at least a focus location of the lens.

Abstract: Some embodiments are directed to an image director of a patient monitoring system to obtain calibration images of a calibration sheet or other calibration object at various orientations and locations. The images are then stored and processed to calculate camera parameters defining the location and orientation of the image detector and identifying internal characteristics of the image detector, and the information are stored. The patient monitoring system can be re-calibrated by using the image detector to obtain an additional image of a calibration sheet or calibration object. The additional image and the stored camera parameters are then used to detect any apparent change in the internal characteristics of the image detector (10)(S6-4).

Abstract: A broadcast subsystem of a processor system includes: a set of broadcast buses, each broadcast bus in the set of broadcast buses electrically coupled to a subset of primary memory units in the set of primary memory units; a primary memory unit queue: configured to store a first set of data transfer requests associated with the set of primary memory units; electrically coupled to the data buffer a broadcast scheduler: electrically coupled to the primary memory unit queue; electrically coupled to the set of broadcast buses; and configured to transfer source data from the data buffer to a target subset of primary memory units in the set of primary memory units via the set of broadcast buses based on the set of data transfer requests stored in the primary memory unit queue.

Abstract: A first projection device includes a first laser projector and a first measurement system. A second projection device includes a second laser projector and a second measurement system. The first projection device and the second projection device is interconnected with a controller. The controller is programmed with computer aided design data representative of a large scale work area and coordinates electronic interaction between the first projection device and the second projection device. The first projection device projects a first indicia that is detectable by the second measurement system and the second projection device projects a second indicia that is detectable by the first measurement system. The controller is adapted for determining relative position within three-dimensional coordinate system of the first projection device to the second projection device from the first indicia detected by the second measurement system and the second indicia detected by the first measurement system.

Abstract: A method and system for controlling projection of optical indicators on a worksurface is disclosed. A projection device for projecting a first optical indicator and a second optical indicator onto a worksurface is provided. A measurement system monitors a work area in which the worksurface is disposed. The measurement system locates a control object within the work area and identifies a marker disposed on the control object. The measurement system monitors a first disposition and a second disposition of the control object. The projection device projects the first optical indicator onto the worksurface and the projection device projects the second optical indicator onto the worksurface in response to manipulation of the control object between the first disposition and the second disposition as detected by said measurement system.

Abstract: A medical visualization apparatus includes two or more imaging devices, two or more robotic arms, multiple magnetic sensors coupled with the imaging devices, and a processor. The two or more imaging devices are configured to acquire images of an organ of a patient. The two or more robotic arms are configured to move the respective imaging devices. The multiple magnetic sensors are configured to output, in response to a magnetic field of a position tracking system, signals indicative of positions and viewing directions of the imaging devices. The processor is configured to estimate a position and a viewing direction of each of the imaging devices based on the signals, and, using the estimated positions and viewing directions, combine the images of the organ acquired by the imaging devices into a virtual reality (VR) image of the organ, and present the VR image to a user on a VR viewer.

Abstract: A contact lens application aid including a lens holder dock structured and dimensioned to receive a lens holder and a light unit optically coupled to the lens holder dock and illuminating the lens holder dock. The contact lens application aid further includes a first supporting member extending downwardly away from the light unit whereby the light unit and lens holder are supported at a desired height above a horizontal work surface. The first supporting member is supported on a surface engaging supporting base coupled to the supporting member. The contact lens application aid enables a user to keep both hands free to manipulate eyelids while applying a contact lens to the eye.

Abstract: A cable television apparatus with a screwless clamping connector structure includes a support structure and at least one rotary connector structure which includes a screwless clamping connection part and a printed circuit board connection part, wherein the screwless clamping connection part includes a first end part which defines an opening to receive a coaxial cable core of a coaxial cable. The at least one rotary connector structure can be rotated to change an opening direction of the opening.

Abstract: A computer-implemented method for determining printing parameter values of an inkjet printing device for printing a pattern on a surface of a spectacle lens substrate is provided. The inkjet printing device includes a printhead with a plurality of printing nozzles. The method includes: grouping the plurality of printing nozzles into at least two printing nozzle groups, and individually determining a printing parameter value for at least one adjustable printing parameter of each printing nozzle group. In addition, a data processing system, a computer program, a non-transitory computer-readable storage medium, a method for inkjet printing, an inkjet printing device, and a spectacle lens substrate with a pattern printed on a surface of the spectacle lens substrate are provided.

Abstract: Methods and devices for measuring the vision of a person are provided The method includes determining a distance between a measurement device and the person. The distance is determined by communicating between a first wireless communication interface of the measurement device and a second wireless communication interface of a portable device on the person. Then, the vision measurement is performed based on the distance.

Abstract: The invention relates to a method for training a machine learning model to identify a subject having at least one machine readable identifier providing a subject ID, said method comprising: providing a computer vision system with an image capturing system comprising at least one image capturing device, and a reader system comprising at least one reader for reading said at least one machine readable identifier; defining said machine learning model in said computer vision system; capturing a first image using said image capturing system, said first image showing said subject; reading said subject ID using said reader system when capturing said first image, and linking said subject ID with said first image, said linking providing said first image with a linked subject ID, providing a first annotated image; capturing at least one further image showing said subject, linking said linked subject ID to said at least one further image providing at least one further annotated image, and subjecting said first annotat

Abstract: The invention relates to a vehicle assembly for a vehicle, the vehicle assembly including a radar sensor having a field of vision and configured to transmit radar waves over a range of wavelengths in the field of vision, and a lens arranged opposite the radar sensor, with the lens being a gradient-index lens and includes a sublayer and a layer of patterns forming a subwavelength-structured dielectric element with a repetition period of the patterns that is less than quarter of a wavelength of the range, and the layer of patterns has a local refractive index which is calculated as a function of a local density of the patterns in the layer.

Abstract: Hats including hair ports are disclosed herein. One hat includes a first portion, a second portion, and a set of bands coupling the first portion and the second portion. Here, the set of bands, the first portion, and the second portion create a set of ports located at a rear portion of the hat. Further, at least one port in the set of ports includes a size that allows the hair of a person wearing the hat to be placed there through.

Abstract: A sealing assembly for a progressive cavity pump and a progressive cavity pump assembly having a retaining sleeve, a ring, and an elastic diaphragm terminating in a first end of the diaphragm in a first opening, and in a second end of the diaphragm, opposite the first end, in a second opening larger than the first opening. The second opening is held in contact with the retaining sleeve by the ring, and the first opening is configured to grip a rotor of the progressive cavity pump, and the ring is configured to hold the second opening fixed with respect to a stator of the progressive cavity pump.

Abstract: The present disclosure relates to a patient motion tracking system for automatic generation of a region of interest on a 3D surface of a patient positioned in a radiotherapy treatment room. More particularly, the disclosure relates to an assistive approach of a motion tracking system, by which a region of interest (ROI) is automatically generated on a generated 3D surface of the patient. Furthermore, a method for automatically generating a ROI on the 3D surface of the patient is described. In particular, all the embodiments refer to systems integrating methods for automatic ROI generation in a radiotherapy treatment setup.