Patents Assigned to W. R. Grace & Co.
  • Method for using synthetic analogs of thrombospondin for inhibiting angiogenesis activity
    Patent number: 5506208
    Abstract: Methods of use of compounds and compositions comprising fragments and synthetic analogs of human thrombospondin are provided for promoting or inhibiting thrombospondin-like activity.
    Type: Grant
    Filed: March 22, 1995
    Date of Patent: April 9, 1996
    Assignees: W. R. Grace & Co.-Conn., The Medical College of Pennsylvania
    Inventors: Jacob Eyal, Bruce K. Hamilton, George P. Tuszynski
  • Compositions containing protease produced by vibrio and method of use in debridement and wound healing
    Patent number: 5505943
    Abstract: Compositions and methods of use are provided for debriding and wound healing applications.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 9, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Donald Z. Fortney, Donald R. Durham
  • Co-extraction of azadirachtin and neem oil
    Patent number: 5503837
    Abstract: Disclosed is an improved method of extracting neem seeds. The method involves co-solvent extracting neem seeds with a solvent mixture of a nonpolar, aliphatic hydrocarbon solvent and a polar solvent to simultaneously remove the hydrophilic and hydrophobic extracts from the neem seeds. The method provides novel neem extract mixtures which contain both the hydrophobic and hydrophilic portion of the neem seeds. The extract mixtures may be further extracted to yield an azadirachtin-containing solid product having greater than 10 weight percent of azadirachtin.
    Type: Grant
    Filed: September 23, 1994
    Date of Patent: April 2, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Michael T. Roland, John J. Blouin
  • Composition for utilizing synthetic polymer packages
    Patent number: 5500470
    Abstract: A water-based bonding agent material made of an acrylic polymer or copolymer emulsion, metal salt complexed with an amine and surfactant is useful for unitizing packages having synthetic polymer surfaces.
    Type: Grant
    Filed: September 6, 1994
    Date of Patent: March 19, 1996
    Assignee: W.R. Grace & Co.-Conn.
    Inventors: Srinivas K. Mirle, Eugene E. Carney
  • Methods and compositions for oxygen scavenging by a rigid semi-rigid article
    Patent number: 5498364
    Abstract: A method of initiating oxygen scavenging by rigid or semi-rigid articles which comprise oxidizable organic compounds and transition metal catalysts is disclosed. The method comprises initiating scavenging by exposing the composition, etc., to radiation. The radiation exposure is preferably electron beam or ultraviolet light and is preferably used on oxygen scavenging compositions which comprise a substituted or unsubstituted ethylenically unsaturated hydrocarbon and a transition metal catalyst. Inclusion of a photoinitiator or antioxidant in the scavenging composition is also preferred to facilitate and/or control the composition's scavenging properties. The method can be used for initiating scavenging in packaging layers or articles for oxygen sensitive products such as food and beverage.
    Type: Grant
    Filed: June 22, 1994
    Date of Patent: March 12, 1996
    Assignee: W.R. Grace & Co.-Conn.
    Inventors: Drew V. Speer, William P. Roberts, Charles R. Morgan
  • Three dimensional sintered inorganic structures using photopolymerization
    Patent number: 5496682
    Abstract: Dense sintered parts of ceramic and/or metallic materials are formed using stereo photolithography. An initial flowable mixture of sinterable inorganic particles, photocurable monomer, photoinitiator and dispersant is flowed over a substrate and cured in a selective pattern. Subsequent layers of the mixture are flowed over the substrate and cured to build a three dimensional body. The body is then fired to produce a dense sintered part. Parts having in excess of 95% of theoretical density can be produced.
    Type: Grant
    Filed: October 15, 1993
    Date of Patent: March 5, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Tariq Quadir, Srinivas K. Mirle, John S. Hallock
  • High efficiency removal of low density lipoprotein-cholesterol from whole blood
    Patent number: 5496637
    Abstract: The present invention relates to the efficient removal of low density lipoprotein cholesterol complex (LDL-C) from whole blood. More specifically, it relates to a process for making a microporous plasmapheresis membrane having an immobilized affinity agent. The immobilized affinity agent is polyacrylic acid bound directly and/or through an interaction with silica and/or calcium chloride to a microporous hollow fiber membrane.
    Type: Grant
    Filed: April 30, 1993
    Date of Patent: March 5, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Marc E. Parham, Richard L. Duffy, Donald T. Nicholson
  • Waterproofing membrane
    Patent number: 5496615
    Abstract: An exemplary waterproofing membrane comprises a carrier layer having a non-bituminous pressure-sensitive waterproofing adhesive, a protective layer coated on the non-bituminous adhesive, and a second waterproofing adhesive layer on the other face of the carrier to permit adherence of the membrane to a cementious surface and to permit concrete to be cast against the non-bituminous layer and protective coating and to be bonded thereto when cured. Further exemplary membranes comprise a dusted layer on the protective coating to permit foot traffic. The membranes of the invention are useful in so-called horizontal and vertical lagging installations. Methods for waterproofing between cementious surfaces, in tunnels, and on concrete decks are also disclosed.
    Type: Grant
    Filed: October 15, 1993
    Date of Patent: March 5, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Keith R. Bartlett, Robert F. Jenkins, Christopher Buss, Timothy J. Martin, Andre Gerber, Peter C. Colarusso
  • Packages and containers comprising salicylic acid chelates as oxygen scavengers
    Patent number: 5492742
    Abstract: An oxygen scavenging packages and containers which comprise a composition of a carrier, such as a polymer, which is permeable to both oxygen and water or water vapor and an oxygen scavenging compound of an organic compound or salt thereof dispersed relatively uniformly throughout the polymer in an amount effective to act as an oxygen scavenger. The oxygen scavenging compound is a salicylic acid chelate or complex of a transition metal or a salt thereof. The oxygen scavenging composition is activated for scavenging oxygen by contact with water or water vapor which permeates into or through the carrier. A reducing agent of an ascorbate compound may be added to enhance the performance of the salicylic acid chelate or complex. The oxygen scavenging compound may be added to the composition in a dry state, and is inactive until activated for oxygen scavenging by contact with water or water vapor.
    Type: Grant
    Filed: August 26, 1994
    Date of Patent: February 20, 1996
    Assignee: W. R. Grace & Co.-Conn
    Inventors: Bruce D. Zenner, Fred N. Teumac, Larrie A. Deardurff, Bert A. Ross
  • Spiral-wound filtration cartridge with longitudinal bypass feature
    Patent number: 5490926
    Abstract: A spiral-wound filtration cartridge, which renders the need for brine seals unnecessary, is disclosed. The spiral cartridges of the invention comprise a spirally-wound inner filtration assembly having an impermeable outer cylindrical surface, a housing having a cylindrical cavity formed therein for receiving the inner filtration assembly, and at least one continuous longitudinally-oriented fluid pathway disposed between the inner filtration assembly and the housing, the fluid pathway allowing for a portion of a fluid entering one end of the filtration cartridge to bypass the inner filtration assembly and proceed to the other end of the filtration cartridge.
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: February 13, 1996
    Assignee: W.R. Grace & Co.-Conn.
    Inventor: Michael Hammeken
  • Oxygen-permeable multilayer film
    Patent number: 5491019
    Abstract: A multilayer film comprises: a first layer comprising a first homogeneous ethylene/.alpha.-olefin copolymer; a second layer comprising a polyolefin; and a third layer comprising a second homogeneous ethylene/.alpha.-olefin copolymer. The second layer is between the first layer and the third layer, the second layer is chemically different from the first layer and the third layer, and the multilayer film has an oxygen transmission rate of from about 500 to 50,000 cc/m.sup.2 /24 hr STP. Also disclosed are a process for making the film, a packaging process using the film, and a product packaged in the film. The film is especially suitable for the packaging of oxygen-sensitive products, such as lettuce, and exhibits exceptional hot tack seal strength.
    Type: Grant
    Filed: March 28, 1994
    Date of Patent: February 13, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventor: Betsy P. Kuo
  • Amorphous nylon composition and films
    Patent number: 5491009
    Abstract: A multi-layer film useful in vacuum skin packaging and other packaging applications, and having a combination of good implosion resistance, formability and high oxygen barrier characteristics, includes a core layer having an oxygen barrier material such as ethylene vinyl alcohol copolymer (EVOH) and a layer or layers comprising an amorphous nylon with or without a low flexural modulus polymeric material such as low modulus nylon (polyamide or copolyamide). Layers of ethylene vinyl acetate copolymer (EVA) or other olefin homopolymers or copolymers, polymeric adhesive layers, a heat-sealable layer, and a heat resistant layer are also disclosed. A composition of matter comprising a blend of an amorphous nylon and a low modulus polymeric material, especially a low modulus nylon, is also disclosed.
    Type: Grant
    Filed: August 3, 1990
    Date of Patent: February 13, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventor: Solomon Bekele
  • Hydronic cooling of particle accelerator window
    Patent number: 5486703
    Abstract: A novel electron beam apparatus window having improved cooling associated therewith, which is in the form of heat pipes located on the window of such apparatus for the cooling of such window by such heat pipes, whereby the heat pipes eliminate the need for air cooling and thus eliminate the production of ozone.
    Type: Grant
    Filed: September 2, 1994
    Date of Patent: January 23, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Joseph R. Lovin, David S. Shevick
  • Impact modified medical film
    Patent number: 5486387
    Abstract: An impact resistant film suitable for medical solution pouches and the packaging of parenteral materials generally includes an interior layer of an ethylene vinyl acetate copolymer and outer layers of a propylene homopolymer or copolymer blended with a styrene ethylene butylene styrene copolymer. In some cases, a flexible copolyester may be substituted for one of the outer blend materials. Sacrificial layers may be optionally be included on one or both outer surfaces of the film to improve processing.
    Type: Grant
    Filed: August 27, 1993
    Date of Patent: January 23, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventor: Walter B. Mueller
  • Packaging material and method of making a packaging material
    Patent number: 5484654
    Abstract: A packaging laminate which includes a layer of polymethylpentene film and a sealant film. The films may be bonded by corona treatment. The laminate displays high oxygen transmission and heat resistance and may be used as a packaging material for produce such as cauliflower, broccoli and lettuce.
    Type: Grant
    Filed: March 12, 1993
    Date of Patent: January 16, 1996
    Assignee: W.R. Grace & Co.
    Inventor: Walter B. Mueller
  • Method of detecting the permeability of an object to oxygen
    Patent number: 5483819
    Abstract: A device for use in a method of detecting the permeability of an article to oxygen is disclosed. A redox indicator and test object are vacuum sealed between a support and a peelable barrier film.
    Type: Grant
    Filed: May 27, 1994
    Date of Patent: January 16, 1996
    Assignee: W.R. Grace & Co.-Conn.
    Inventors: Charles R. Barmore, Christopher Bull
  • Method & apparatus for sealing fitment tubes into pouches
    Patent number: 5484375
    Abstract: The present invention relates to a method of heat sealing fitment tubes to pouches or bags of flexible film using a pair of hot bars. Also disclosed is the use of warm bars or cold bars to cool the hot bar seal. An apparatus for producing pouches with fitment tubes sealed thereto as well as the pouches so produced is also disclosed.
    Type: Grant
    Filed: March 11, 1994
    Date of Patent: January 16, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Joseph E. Owensby, Gregory E. McDonald
  • Method and apparatus for loading bags
    Patent number: 5483784
    Abstract: An apparatus for, and a method of, loading a meat product into a thermoplastic bag or casing is disclosed. Particularly, the present invention discloses an apparatus for, and method of, loading a meat product into a thermoplastic bag or casing such that the area used to produce a heat seal closure of the bag or casing is protected against contamination during the product loading process.
    Type: Grant
    Filed: August 31, 1993
    Date of Patent: January 16, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Joseph E. Owensby, Howard D. Conner, Frederick A. Dobbins
  • Method for application of smoke color to inside of bag and apparatus therefor
    Patent number: 5484001
    Abstract: A method of packaging meat emulsion in a flexible thermoplastic bag, wherein the bag has dispersed on its insides, prior to insertion of the meat emulsion into the bag, additives such as liquid colorant or liquid smoke, via a squeeze roller and backing plate (or two squeeze rollers), is shown. An apparatus for dispersing the additives via a squeeze roller and backing plate (or two squeeze rollers) is also shown.
    Type: Grant
    Filed: June 15, 1993
    Date of Patent: January 16, 1996
    Assignee: W. R. Grace & Co.-Conn
    Inventor: Stephen L. Gray
  • Cross-linked film
    Patent number: 5482769
    Abstract: A cross-linkable, preferably stretch oriented film comprising a blend of a polyolefin and a diene polymer and a transition metal catalyst, wherein the blend cross-links in the presence of oxygen without irradiation to provide a film with high heat resistance.
    Type: Grant
    Filed: June 1, 1994
    Date of Patent: January 9, 1996
    Assignee: W. R. Grace & Co.-Conn.
    Inventor: Henry G. Schirmer