Abstract: Disclosed herein are embodiments of methods for detecting the presence of and amount of drugs in a sample, particularly a particle sample obtained from a subject. In particular disclosed embodiments, the particle samples are skin particle samples, saliva particle samples, and/or mucous samples isolated from a subject and analyzed using thermal desorption methods combined with a selected detection method.
Type:
Grant
Filed:
December 20, 2018
Date of Patent:
August 15, 2023
Assignee:
Washington State University
Inventors:
Herbert H. Hill, Jr., Brian Clowers, Nicholas Lovrich
Abstract: Methods of controlling the maturation of plants and/or plant products (e.g. fruit, vegetable, ornamentals, etc.) by manipulating Alternative Oxidase (AOX) activity. An increase in activity hastens the maturation process while a decrease in activity slows or stops maturation.
Type:
Grant
Filed:
December 16, 2019
Date of Patent:
July 4, 2023
Assignee:
Washington State University
Inventors:
Amit Dhingra, Seanna L. Hewitt, Evan C. Stowe
Abstract: Modular pressurized hotbox for use and substitution in a variety of pressurized electrochemical applications to include reversible solid oxide electrolyzer and fuel cells, energy storage systems, renewable fuel production, solid-state hydrogen pumping and liquefaction, and oxygen transport membranes. This is enabled by mixed electronic and ionic conducting compositions of vanadia-yttria and vanadia-calcia stabilized zirconia and a dry powder method of manufacture for ceramic core stacks.
Abstract: Compositions and methods for protecting bees from toxins and for preventing or decreasing colony collapse are provided. The compositions comprise carbon microparticles which, when ingested by bees, increase their survival after exposure to toxins such as pesticides.
Type:
Grant
Filed:
January 18, 2019
Date of Patent:
March 21, 2023
Assignee:
Washington State University
Inventors:
Waled Suliman, Brandon Hopkins, Manuel Garcia-Perez
Abstract: Modular pressurized hotbox for use and substitution in a variety of pressurized electrochemical applications to include reversible solid oxide electrolyzer and fuel cells, energy storage systems, renewable fuel production, solid-state hydrogen pumping and liquefaction, and oxygen transport membranes. This is enabled by mixed electronic and ionic conducting compositions of vanadia-yttria and vanadia-calcia stabilized zirconia and a dry powder method of manufacture for ceramic core stacks.
Abstract: An N-element baseband (BB) time-domain spatial signal processor system and methodology for large modulated bandwidth multi-antenna receivers are provided. Such a processor generally includes a pipeline converter configured as an asynchronous time-to-digital converter, wherein the asynchronous time-to-digital converter arrangement generates a residue value and an asynchronous pulse and is further arranged to amplify the residue value so as to result in an amplified residue value; and a 2-bit flash time-to-digital-converter configured to quantize the amplified residue value. Thus, a true-time delay spatial signal processing system and technique in the time-domain that enables beamforming, beam-nulling and multiple independent interference cancellation after time-alignment of signals using cascaded voltage-to-time converters and quantization using relaxed pipeline time-to-digital converters is presented.
Abstract: A magnetic/energetic apparatus for purifying gas mixtures comprises a vortex tube and magnetic elements. Such an apparatus can include an inlet valve configured to receive a gas mixture having one or more disposed paramagnetic gas species and one or more diamagnetic gas species; a high-shear environment energetic separation chamber coupled to the inlet valve; a plurality of magnetic elements coupled to an outer wall of the high-shear environment separation chamber, wherein each of the plurality of magnetic elements are arranged so as to have a respective pole alternating in polarity with respect to an adjacently positioned magnetic element so as to induce a field gradient between each of the adjacently positioned magnetic elements and within the inner wall of the high-shear environment separation chamber; and at least one exit valve so as provide a substantially separated one or more paramagnetic gas species from the one or more diamagnetic gas species.
Type:
Grant
Filed:
September 16, 2019
Date of Patent:
February 14, 2023
Assignee:
Washington State University
Inventors:
Jacob Leachman, Carl Bunge, Jordan Raymond
Abstract: Compounds of Marlush formula (I) described in the claims are useful in diagnostic methods for detecting and/or identifying cells presenting PSMA. Disclosed are also methods for preparing the compounds.
Type:
Grant
Filed:
March 14, 2014
Date of Patent:
January 17, 2023
Assignees:
CANCER TARGETED TECHNOLOGY LLC, WASHINGTON STATE UNIVERSITY
Abstract: A physical environment is equipped with a plurality of sensors (e.g., motion sensors). As individuals perform various activities within the physical environment, sensor readings are received from one or more of the sensors. Based on the sensor readings, activities being performed by the individuals are recognized and the sensor data is labeled based on the recognized activities. Future activity occurrences are predicted based on the labeled sensor data. Activity prompts may be generated and/or facility automation may be performed for one or more future activity occurrences.
Type:
Grant
Filed:
September 26, 2019
Date of Patent:
January 10, 2023
Assignee:
Washington State University
Inventors:
Diane J. Cook, Bryan Minor, Janardhan Rao Doppa
Abstract: A deicing formulation, comprising a chemically degraded extract derived from biowaste; and a salt is provided. Methods for preventing ice formation or removing ice from a surface by applying the deicing formula made of chemically degraded extract derived from biowaste and a salt to the surface are also provided.
Abstract: Devices and methods for simultaneously measuring, in real time: 1) volumetric changes of a mammalian breast due to milk production and output, and 2) breast temperature, are provided. The devices are generally sensors which can be disposed within a wearable garment such as a bra.
Type:
Grant
Filed:
May 31, 2018
Date of Patent:
December 13, 2022
Assignee:
WASHINGTON STATE UNIVERSITY
Inventors:
Bulent Arda Gozen, Michelle Kay McGuire, Abhishek Gannarapu, Kimberly Ann Lackey, Tyler Nelson Meine, Dallas Daaren Chang
Abstract: Silicon materials suitable for use as an anode material and associated method of production are disclosed herein. In one embodiment, a silicon material includes crystalline silicon in a matrix and macro-scale pores distributed in the matrix of the crystalline silicon. The macro-scale pores can have a size greater than 100 nanometers, and surfaces of crystalline silicon in the macro-scale pores are coated with carbon.
Abstract: A query suggestion to expand an initial query is calculated whereby the cost of the expanded initial query is bounded in both time and quality. The user validates a subset of the top-n answers Q(G) to a query Q and provides adjusted configuration parameters. The top-n diversified ?-expansion terms Q? are calculated from the validated subset of answers Q(G) to the query Q and are provided to an interactive user interface for selection. Answers Q?(G) for the top-n diversified ?-expansion terms Q? are cost bounded by cost threshold ? and exploration range r specified by the user. The user selects a new term of terms Q? and an incremental query evaluation of the new term is invoked to compute expanded query answers Q?(G) by incrementally updating the validated subset of answers Q(G), without re-evaluating an expanded query Q? including the new term from scratch.
Type:
Grant
Filed:
November 12, 2020
Date of Patent:
November 29, 2022
Assignees:
Huawei Technologies Co., Ltd., Washington State University
Inventors:
Mohammad Hossein Namaki, Yinghui Wu, Xin Zhang, Yonghua Ding
Abstract: A deep neural network (DNN) media noise predictor configured for one-dimensional-magnetic (1DMR) recording or two-dimensional-magnetic (TDMR) is introduced. Such architectures are often combined with a trellis-based intersymbol interference (ISI) detection component in a turbo architecture to avoid the state explosion problem by separating the inter-symbol interference (ISI) detection and media noise estimation into two separate detectors and uses the turbo-principle to exchange information between them so as to address the modeling problem by way of training a DNN-based media noise estimators. Thus, beneficial aspects include a reduced bit-error rate (BER), an increased areal density, and a reduction in computational complexity and computational time.
Type:
Grant
Filed:
June 1, 2020
Date of Patent:
September 6, 2022
Assignee:
WASHINGTON STATE UNIVERSITY
Inventors:
Benjamin Joseph Belzer, Krishnamoorthy Sivakumar, Jinlu Shen, Ahmed Aboutaleb, Amirhossein Sayyafan
Abstract: Application of a new light-molecule interaction in which molecules enable emission of photons with more energy than that of the absorbed photons achieves higher resolution than fluorescence imaging. This emission phenomenon is termed supracence and is applied to obtain more information about the structure and properties of a specimen than currently possible with fluorescence imaging techniques. Because supracence originates from chemical bonds, any structure that contains chemical bonds meets the necessary condition to potentially emit supracence. Super spectral resolution images are achieved by selectively exciting a target molecule to suprace without exciting another fluorophore that has absorption and emission rather close to the target.
Abstract: The disclosure relates to antigen detection reagents and related methods, systems, and kits. The reagents comprise an antigen-binding molecule conjugated to an inorganic component. In some embodiments, the inorganic component possesses catalytic functionality to provide a detectable signal. In some embodiments, the catalytic inorganic component is or comprises a bimetallic nanoparticle. In other embodiments, the inorganic component is a nanoflowers that provides a physical scaffold onto which the antigen-binding component and a reporter component can be loaded, resulting in augmented antigen-binding and reporting capabilities.
Type:
Application
Filed:
March 14, 2022
Publication date:
September 1, 2022
Applicant:
Washington State University
Inventors:
Yuehe Lin, Dan Du, Yang Song, Ranfeng Ye
Abstract: A centrifugal bioreactor includes a turntable assembly, an electric motor coupled to the turntable assembly, and a replaceable rotor assembly coupled to the turntable assembly. The replaceable rotor assembly includes a plurality of reaction chambers that house cell cultures. A fresh medium tank holds fresh medium for the cell cultures, a spent medium tank holds a first portion of spent medium produced by the cell cultures, and an inoculation tank combines the fresh medium from the fresh medium tank and a second portion of the spent medium. A gas exchanger exposes the fresh medium and the second portion of the spent medium to gas. Additionally, a first pump supplies the fresh medium and the second portion of the spent medium to the plurality of the reaction chambers, and a second pump discard the first portion of the spent medium to the spent medium tank.
Type:
Application
Filed:
November 16, 2021
Publication date:
May 19, 2022
Applicant:
Washington State University
Inventors:
Bernard J. Van Wie, Kitana M. Kaiphanliam, Brenden Fraser-Hevlin, Eric S. Barrow
Abstract: The disclosure relates to antigen detection reagents and related methods, systems, and kits. The reagents comprise an antigen-binding molecule conjugated to an inorganic component. In some embodiments, the inorganic component possesses catalytic functionality to provide a detectable signal. In some embodiments, the catalytic inorganic component is or comprises a bimetallic nanoparticle. In other embodiments, the inorganic component is a nanoflowers that provides a physical scaffold onto which the antigen-binding component and a reporter component can be loaded, resulting in augmented antigen-binding and reporting capabilities.
Type:
Grant
Filed:
April 24, 2017
Date of Patent:
April 19, 2022
Assignee:
Washington State University
Inventors:
Yuehe Lin, Dan Du, Yang Song, Ranfeng Ye
Abstract: Described herein are vectors, such as adeno-associated virus (AAV) vectors, and recombinant AAV expressing Smad7. The disclosed AAV vectors and rAAV can be used for therapeutic applications in the treatment and amelioration of muscle wasting, cardiac and/or skeletal muscle wasting associated with cancer cachexia.
Type:
Grant
Filed:
April 22, 2016
Date of Patent:
March 8, 2022
Assignees:
Washington State University, Baker Heart and Diabetes Institute
Abstract: A new and distinct variety of ‘Malus domestica’ apple tree named ‘WA 64’ and produced from a controlled cross of ‘Honeycrisp’ and ‘Cripps Pink’ is described herein. ‘WA 64’ is distinctly different from each of its parents and other mid-season apples.