Patents Assigned to William H. Rorer, Inc.
  • Patent number: 4725686
    Abstract: A method for increasing cardiotonic contractility in humans or other animals using a class of benzodiazinonepryidazinone and hydroxy-pyrazolyl compounds and pharmaceutical compositions including the same.
    Type: Grant
    Filed: November 22, 1985
    Date of Patent: February 16, 1988
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt, William C. Faith, Bruce F. Molino
  • Patent number: 4692329
    Abstract: Process and composition for the topical treatment of acne which comprises as ingredients a peroxide of an organic acid and an erythromycin compound selected from the group consisting of erythromycin and its stearate and glucoheptonate derivatives and in which said peroxide is from one-half to thirty times, the weight of said erythromycin compound, and a suitable pharmaceutically acceptable carrier.
    Type: Grant
    Filed: July 3, 1984
    Date of Patent: September 8, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Robert W. Klein, Mary E. Foxx
  • Patent number: 4689335
    Abstract: A method for treating gastrointestinal motility dysfunctions using phenylheterocyclic guanidines and novel heterocyclic guanidine compounds.
    Type: Grant
    Filed: January 13, 1984
    Date of Patent: August 25, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, William L. Studt, Henry F. Campbell, John Yelnosky
  • Patent number: 4668673
    Abstract: A class of bicyclic benzo-oxy heterocyclic ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: July 2, 1986
    Date of Patent: May 26, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt, Kent W. Neuenschwander
  • Patent number: 4666913
    Abstract: A method for increasing cardiotonic contractility in humans or other animals using a class of hydroxy and aminothiazolyl-benzodiazinone compounds and pharmaceutical compositions including the same.
    Type: Grant
    Filed: November 22, 1985
    Date of Patent: May 19, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kubla, Henry F. Campbell, William L. Studt, Bruce F. Molino, Thomas J. Tucker
  • Patent number: 4647559
    Abstract: A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: May 23, 1986
    Date of Patent: March 3, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt
  • Patent number: 4639442
    Abstract: A class of benzocyclobutene aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: November 1, 1985
    Date of Patent: January 27, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt
  • Patent number: 4638001
    Abstract: A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: April 27, 1984
    Date of Patent: January 20, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt
  • Patent number: 4637528
    Abstract: A sliding and pivoting joint, and a retractable medicament spray dispenser having such a joint. A sleeve is telescopically mounted on the dispenser housing by engaging a pair of pin-like projections on a pair of ears on the sleeve into slots which are in opposite side walls of the housing. An elongated stud protrudes perpendicularly from the inward end of each pin. When the sleeve has been telescopically extended relative to the housing, abutments in the housing interact with the protruding studs to prevent the sleeve from being pivoted to any positions beyond those which correspond to the storage and the operating configurations of the dispenser.
    Type: Grant
    Filed: January 19, 1984
    Date of Patent: January 20, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Clarence A. Wachinski, Thomas J. Bigger
  • Patent number: 4632927
    Abstract: A class of bicyclic nitrogen heterocyclic ether and thioether compounds exhibiting pharmacological activity including cytoprotective, H.sub.2 -antagonist, anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions are disclosed.
    Type: Grant
    Filed: March 20, 1984
    Date of Patent: December 30, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: Henry F. Campbell, Donald E. Kuhla, William L. Studt, Stuart A. Dodson
  • Patent number: 4612309
    Abstract: A class of bicyclic benzo-oxy heterocyclic ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastro-intestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: October 23, 1984
    Date of Patent: September 16, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt, Kent W. Neuenschwander
  • Patent number: 4611011
    Abstract: 1-Phenyl-3N-alkyl amidinoureas are useful in the treatment of irritable bowel syndrome.
    Type: Grant
    Filed: January 13, 1984
    Date of Patent: September 9, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: John Yelnosky, Ghulam N. Mir
  • Patent number: 4605551
    Abstract: This invention relates to an improvement comprising coating agitated particles of substantially anhydrous antacid with a solvent-free mixture of electronegatively charged material in a non-toxic inert substantially water insoluble oil.
    Type: Grant
    Filed: November 30, 1984
    Date of Patent: August 12, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: John D. Buehler, Hans J. Medal, Gregory A. Rhoa
  • Patent number: 4595683
    Abstract: A class of 3- and 5-amino thiatriazine compounds exhibiting pharmacological activity, including gastrointestinal anti-ulcerogenic and cytoprotective activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: October 23, 1984
    Date of Patent: June 17, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt, Stuart A. Dodson
  • Patent number: 4593028
    Abstract: Cardiotonic 5-heteroaryl-substituted-2-pyridone compounds, pharamaceutical compositions, and a method for the treatment of congestive heart failure.
    Type: Grant
    Filed: April 19, 1984
    Date of Patent: June 3, 1986
    Assignee: William H. Rorer, Inc.
    Inventor: Henry F. Campbell
  • Patent number: 4588719
    Abstract: A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: October 24, 1984
    Date of Patent: May 13, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: William L. Studt, Donald E. Kuhla, Henry F. Campbell
  • Patent number: 4565826
    Abstract: This invention relates to a novel class of heterocyclic amidinourea and heterocyclic amidinothiourea compounds wherein the heterocyclic substitution is at the 1-N urea nitrogen atom. These compounds exhibit pharmaceutical activity and may be incorporated into pharmaceutical preparations for producing anti-ulcerogenic, antisecretory, antispasmodic, antimotility, cardiovascular, antidiarrheal or antiparasitic action.
    Type: Grant
    Filed: February 24, 1984
    Date of Patent: January 21, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: William L. Studt, Harry K. Zimmerman, George H. Douglas
  • Patent number: 4564640
    Abstract: A method of inducing blood pressure reduction in humans and mammals by administering 2,6-disubstituted phenyl N-alkyl amidinoureas in which the phenyl ring is additionally substituted by a hydroxy, alkoxy, aralkoxy, alkenyloxy, alkynyloxy, acyloxy or halo acyloxy group and a novel class of amidinourea compounds having pharmaceutical uses, including blood pressure lowering activity.
    Type: Grant
    Filed: February 2, 1984
    Date of Patent: January 14, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: William L. Studt, Richard L. Riley, George H. Douglas
  • Patent number: 4563460
    Abstract: A method for treating gastrointestinal motility dysfunctions using 2-amino-quinoline and -quinazoline derivatives.
    Type: Grant
    Filed: January 13, 1984
    Date of Patent: January 7, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, William L. Studt, Henry F. Campbell, John Yelnosky
  • Patent number: 4563456
    Abstract: Method for treating gastrointestinal motility dysfunctions using 1,2,4-triazines.
    Type: Grant
    Filed: January 13, 1984
    Date of Patent: January 7, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, William L. Studt, Henry F. Campbell, John Yelnosky