Abstract: A transient-voltage-suppression protection device and a manufacturing process therefor, and an electronic product. The transient-voltage-suppression protection device includes a substrate, a first trap, a second trap, a first injection region, and a second injection region, where the first trap and the second trap are sequentially arranged on the substrate from left to right at an interval, have a same doping type that is opposite to a doping type of the substrate, and are respectively provided with the first injection region and the second injection region with opposite doping types. The electronic product includes the transient-voltage-suppression protection device. In the solutions described, protection can be triggered and started at a lower voltage; the capacitance is small, and the manufacturing process is simple.

Abstract: The present disclosure provides a method of increasing the functionality of a GABAergic interneuron in the hilus of the hippocampus of an individual having at least one apolipoprotein E4 (apoE4) allele. The method generally involves reducing tau levels in the interneuron.

Abstract: Disclosed is a device, for matching oral scan data, comprising a first matching unit, a teeth segmentation unit, and a second matching unit. The first matching unit matches a coordinate system of three-dimensional oral scan data to a coordinate system of a three-dimensional oral computed tomography (CT) image by using three-dimensional feature points of the three-dimensional oral scan data and three-dimensional feature points of the three-dimensional oral CT image. The teeth segmentation unit segments teeth from the three-dimensional oral scan data on the basis of the three-dimensional feature points of the three-dimensional oral scan data to generate surface information relating to the segmented teeth. The second matching unit matches the three-dimensional oral scan data and the three-dimensional oral CT image, which have matching coordinate systems, by means of the surface information.

Abstract: Disclosed is a three-dimensional oral scan data matching device including a matching unit, a deep-learning unit, a scanned frame feature determination unit, and a scan data re-matching unit. The matching unit matches a plurality of scanned frames to generate a full mouth image. The deep-learning unit performs deep-learning to detect a feature of the full mouth image. The scanned frame feature determination unit determines a feature of the plurality of scanned frames by utilizing the feature of the full mouth image. The scan data re-matching unit re-matches the plurality of scanned frames on the basis of the feature of the plurality of scanned frames, to reconstruct a three-dimensional oral model.

Abstract: Disclosed is a device for matching three-dimensional intra-oral scan data, the device comprising a computed tomography (CT) image depth map generation unit, a depth map coordinate difference information determination unit, a depth map correction unit, and an intra-oral scan model recovery unit. The CT image depth map generation unit generates a depth map of a CT frame from a CT image by using information about a single scan frame of the scan data. The depth map coordinate difference information determination unit determines depth map coordinate difference information between the depth map of the CT frame and a depth map of the scan frame. The depth map correction unit corrects the depth map of the scan frame on the basis of the depth map coordinate difference information. The intra-oral scan model recovery unit recovers a three-dimensional intra-oral scan model on the basis of the corrected depth map of the scan frame.

Abstract: The invention relates to devices, methods, kits, and compositions for in vitro generation of three-dimensional micro-tissues that are accurate models of heart, skeletal muscle, neuronal, and other tissues.

Abstract: The present invention includes: a first current source, through which a first current is made to flow; a second current source, through which a second current set at a certain ratio to the first current is made to flow; a first current path, which includes a second resistor, a first resistor, and a first bipolar transistor that are connected to the first current source in a sequential manner, and through which the first current is made to flow; a second current path, which includes a third resistor and a 0th bipolar transistor that are connected to the second current source in a sequential manner, and through which the second current is made to flow; an operational amplifier, which controls current amounts of the first current and the second current by an output from an output end, and of which a positive input end is connected to a connection point between the second resistor and the first resistor, and of which a negative input end is connected to a connection point between the third resistor and the 0th bi

Abstract: A system, and method for capture of multiple liquid samples from an aerial drone, including an aerial drone; one or more liquid sample receptacles disposed within respective receptacle containing units provided on the aerial drone; and a gear drive mechanism configured to lower and raise the one or more liquid sample receptacles and the respective receptacle containing units into a body of liquid to capture multiple liquid samples from the body of liquid.

Abstract: Methods of generating spinal cord glutamatergic interneurons (V2a interneurons) from human pluripotent stem cells (hPSCs) are provided. A method of the present disclosure may include culturing a first population of hPSCs in vitro in a neural induction medium that includes: a retinoic acid signaling pathway activator; a sonic hedgehog (Shh) signaling pathway activator; and a Notch signaling pathway inhibitor, wherein the culturing results in generation of a second population of cultured cells containing CHX10+ V2a interneurons. Also provided are non-human animal models that include the hPSC-derived spinal cord glutamatergic interneurons, and methods of producing the non-human animal models.

Abstract: Provided is a probe card including a lower plate, an upper plate spaced apart from the lower plate, and a needle that extends vertically to penetrate the lower plate and the upper plate, wherein the needle includes a first member that extends vertically and includes a first material, and a second member horizontally connected to the first member, wherein the second member includes a second material different from the first material.

Abstract: A device and method for detecting control-point activation conditions corresponding to a portion of a glove body coming in contact with or being within a threshold distance from at least one of another portion of the glove body or a control surface separate from the glove body. The glove may include a conductive path attached to the glove body and an expanded conductive area conductively coupled to the conductive path and attached to the glove body. The expanded conductive area may be wider than individual portions of the conductive path.

Abstract: A system and methods for streamlining the legal client intake process and revolutionizing the way legal representation in general is effectuated is disclosed. The system includes an intake platform, and optionally includes one or more of the following modules which interface with the intake platform: a scheduling module, a messaging client, a documents database, a virtual meeting platform, a client database, an attorney database, a payment module. The system is capable of formalizing an engagement for legal services between the user and a practitioner selected by the user, generating drafts of legal documents, sending drafts of such legal documents to the user and practitioner, scheduling an initial meeting between the user and practitioner, and soliciting and accepting payment for legal services, via a single platform.

Abstract: The clock generation circuit outputs a clock signal with a constant cycle by repeating the following operations: when an enable signal becomes a H level, the clock signal immediately rises, and a sense end is changed to a L level via a first capacitor, then a voltage of the sense end is gradually increased via a resistor, and when the sense end reaches a predetermined potential, an output of a second inverter becomes the L level, the clock signal becomes the L level, an inverted clock signal becomes the H level, and accordingly the sense end becomes the H level; and thereafter, a current flows via the resistor so that the voltage of the sense end decreases gradually, when the sense end reaches a predetermined potential, the output of the second inverter becomes a H level, the clock signal becomes the H level, the sense end is changed to a L level via the first capacitor, then the voltage of the sense end is gradually increased via the resistor, and when the sense end reaches a predetermined potential, the out

Abstract: A magnet is embedded in a flexible elastic material, providing a means of temporarily connecting the flexible elastic material to ferromagnetic objects. A rigid cup provides a container for anchoring the magnet in the flexible elastic material. The cup also provides a structure to bind with the flexible elastic material. The magnet rests in the base of the cup, which extends past the surface of the material, allowing the magnet's forces to extend outside the base of the cup. The remainder of the cup resides within the material.

Abstract: The present disclosure provides compositions and methods for reactivating latent immunodeficiency virus using a glycogen synthase kinase 3? inhibitor, such as a glycogen synthase kinase 3? (GSK-3?) or a glycogen synthase kinase 3? (GSK-3?) inhibitor. In some embodiments, the glycogen synthase kinase 3 inhibitor is a glycogen synthase kinase antagonist, e.g., Tideglusib (4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione), or a pharmaceutically acceptable salt or derivative thereof. In other embodiments, the glycogen synthase kinase 3 inhibitor is a maleimide-based glycogen synthase kinase 3 inhibitor, e.g., SB-216763 (3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione) or a pharmaceutically acceptable salt or derivative thereof.

Abstract: A tilting and telescoping mast assembly having a compact device footprint that can be mounted in close proximity to, for example, a front wall of a truck bed (e.g., adjacent the cab) thereby reducing dead space within the truck bed and maximizing cargo space within the bed. The mast of the present disclosure is configured to be supported by its base in a first position when in the horizontal orientation and supported in a second position when in the vertical orientation, with the first and second positions being spaced apart horizontally and/or vertically.

Abstract: The present invention provides compositions exhibiting in vivo activity of fibrin in an in vitro setting, in vitro assays comprising such compositions, methods of producing such compositions, and methods of using such compositions and assays. The compositions of the invention include molecules with the biochemical properties of 1) high affinity binding to fibrin receptors and 2) activation of cell-signaling systems comparable to that observed in vivo by fibrin. The fibrin compositions of the invention are compatible both in biochemical assays and cell-based assays, and thus useful for in vitro assays for screening of test agents that modulate cell activation and/or signaling pathways mediated by fibrin or associated with fibrin activity.

Abstract: The present disclosure provides methods for inducing cell cycle reentry of postmitotic cell. The present disclosure further provides cells and compositions for treating diseases, such as cardiovascular diseases, neural disorders, hearing loss, and diabetes.

Abstract: A transient-voltage-suppression protection device and a manufacturing process therefor, and an electronic product. The transient-voltage-suppression protection device includes a substrate, a first trap, a second trap, a first injection region, and a second injection region, where the first trap and the second trap are sequentially arranged on the substrate from left to right at an interval, have a same doping type that is opposite to a doping type of the substrate, and are respectively provided with the first injection region and the second injection region with opposite doping types. The electronic product includes the transient-voltage-suppression protection device. In the solutions described, protection can be triggered and started at a lower voltage; the capacitance is small, and the manufacturing process is simple.

Abstract: A water-based paint includes a fine powder composition which includes fine powdery clay minerals comprising pyrophyllite and sepiolite, a fine powdery thixotropy support agent containing hydroxypropyl methylcellulose and comprising first and second agents having 2 percent by weight aqueous solution viscosities at 20° C. of 2400 mPa·S to 4500 mPa·S and 64000 mPa·S to 90000 mPa·S, respectively, and a fine powdery inorganic porous material comprising diatomaceous earth and zeolite. A thixotropic index when the fine powder composition is dispersed and dissolved in water is 3.0 to 4.0. The thixotropy support agent includes 67 to 91 percent by weight of the first agent and 9 to 33 percent by weight of the second agent.