Patents Assigned to Wyeth
  • Nutritional formulation containing prebiotic substances
    Patent number: 6630452
    Abstract: A nutritional composition is provided which comprises oligofructose and sialyllactose.
    Type: Grant
    Filed: February 7, 2001
    Date of Patent: October 7, 2003
    Assignee: Wyeth
    Inventor: Jeffrey L. Wilson
  • Process for synthesizing N-aryl piperazines with chiral N'-1-[benzoyl(2-pyridyl)amino]-2-propane substitution
    Publication number: 20030187265
    Abstract: A process for formation of N-aryl piperazines with chiral N′-1-[benzoyl(2-pyridyl)amino]-2-propane side-chains having the structure shown in formula below, and for making intermediate compounds therefor.
    Type: Application
    Filed: March 10, 2003
    Publication date: October 2, 2003
    Applicant: Wyeth
    Inventors: Gregg Brian Feigelson, Joseph Zeldis, Ivo Jirkovsky
  • Uses for indoletetrahydropyridine derivatives of 2,3-dihydro-7H-[1,4]dioxino-[2,3-e]indole
    Patent number: 6627639
    Abstract: Compounds of the formula are useful in the treatment of central nervous system disorders including depression, obsessive compulsive disorder, panic attacks, generalized anxiety disorder, sexual dysfunction, eating disorders and addictive disorders caused by ethanol or cocaine abuse.
    Type: Grant
    Filed: January 9, 2003
    Date of Patent: September 30, 2003
    Assignee: Wyeth
    Inventors: Gary P. Stack, Megan Tran, Byron A. Bravo
  • Follistatin domain containing proteins
    Publication number: 20030180306
    Abstract: The present invention relates to the use of proteins comprising at least one follistatin domain to modulate the level or activity of growth and differentiation factor-8 (GDF-8). More particularly, the invention relates to the use of proteins comprising at least one follistatin domain, excluding follistatin itself, for treating disorders that are related to modulation of the level or activity of GDF-8. The invention is useful for treating muscular diseases and disorders, particularly those in which an increase in muscle tissue would be therapeutically beneficial. The invention is also useful for treating diseases and disorders related to metabolism, adipose tissue, and bone degeneration.
    Type: Application
    Filed: February 21, 2003
    Publication date: September 25, 2003
    Applicant: WYETH
    Inventors: Jennifer J. Hill, Neil M. Wolfman
  • Substituted phenyl naphthalenes as estrogenic agents
    Publication number: 20030181519
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure 1
    Type: Application
    Filed: December 11, 2002
    Publication date: September 25, 2003
    Applicant: Wyeth
    Inventors: Richard E. Mewshaw, Richard J. Edsall, Cuijian Yang, Heather A. Harris, James C. Keith, Leo M. Albert
  • Treatments using venlafaxine
    Publication number: 20030181517
    Abstract: This invention provides a method of treating obesity, generalized anxiety disorder, post-traumatic stress disorder, late luteal phase dysphoric disorder (premenstrual syndrome), attention deficit disorder, with and without hyperactivity, Gilles de la Tourette syndrome, bulimia nervosa or Shy Drager Syndrome in a mammal by administering to the mammal an effective amount of a hydroxycycloalkanephenethyl amine of the following structural formula: 1
    Type: Application
    Filed: March 25, 2003
    Publication date: September 25, 2003
    Applicant: Wyeth
    Inventors: Richard L. Rudolph, Albert T. Derivan, Eric A. Muth, G. Virginia Upton
  • 2-substituted thiazolidinones as beta-3 adrenergic receptor agonists
    Publication number: 20030176412
    Abstract: This invention provides compounds of Formula I having the structure 1
    Type: Application
    Filed: May 19, 2003
    Publication date: September 18, 2003
    Applicant: Wyeth
    Inventor: Baihua Hu
  • Method of inhibiting cell death
    Publication number: 20030176455
    Abstract: This invention provides a method of inhibiting cell death in a mammal in need thereof, which comprises providing said mammal with an effective amount of a rapamycin
    Type: Application
    Filed: March 10, 2003
    Publication date: September 18, 2003
    Applicant: Wyeth
    Inventor: Steven J. Adelman
  • Substituted 6H-DiBenzo[c,h]chromenes as estrogenic agents
    Publication number: 20030176491
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure 1
    Type: Application
    Filed: December 11, 2002
    Publication date: September 18, 2003
    Applicant: Wyeth
    Inventors: Richard E. Mewshaw, Richard J. Edsall, Stephen T. Cohn, Heather A. Harris, James C. Keith, Leo M. Albert
  • Pyridobenzodiazepine and pyridobenzoxazepine carboxyamide vasopressin agonists
    Patent number: 6620807
    Abstract: The present invention provides benzoheterocyclic carboxyamides, particularly pyridobenzodiazepine and pyridobenzoxazepine carboxyamides, of the general formula: wherein: W is O or NH, optionally substituted, as well as methods and pharmaceutical compositions utilizing these compounds for providing a temporary delay of urination or for the treatment of disorder which may be remedied or alleviated by vasopressin agonist activity, including diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, bleeding or coagulation disorders.
    Type: Grant
    Filed: February 1, 2000
    Date of Patent: September 16, 2003
    Assignee: Wyeth
    Inventors: Robert J. Steffan, Amedeo A. Failli
  • Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
    Publication number: 20030171395
    Abstract: The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor.
    Type: Application
    Filed: December 19, 2002
    Publication date: September 11, 2003
    Applicant: Wyeth
    Inventors: Ronald Charles Bernotas, Derek Cecil Cole, William Joseph Lennox
  • Naphthyl benzoxazoles and benzisoxazoles as estrogenic agents
    Publication number: 20030171412
    Abstract: This invention provides estrogen receptor modulators of formula 1, having the structure 1
    Type: Application
    Filed: December 11, 2002
    Publication date: September 11, 2003
    Applicant: Wyeth
    Inventors: Michael S. Malamas, Iwan Gunawan, Heather A. Harris, James C. Keith, Leo M. Albert
  • Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
    Publication number: 20030171353
    Abstract: The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor.
    Type: Application
    Filed: December 19, 2002
    Publication date: September 11, 2003
    Applicant: Wyeth
    Inventors: Derek Cecil Cole, Joseph Raymond Stock, William Joseph Lennox, Ping Zhou
  • Selection of poultry Eimeria strains through extra-intestinal sporozoites
    Publication number: 20030170277
    Abstract: A method for obtaining an immunogenic strain useful for producing a vaccine against Coccidiosis comprises the cycle of infecting at least one first group of specific pathogen-free donor birds with oocysts from an Eimeria species. Blood is then collected from these donor birds, and is then used to infect a second group of specific pathogen-free birds. Oocysts are collected from the second group of birds. These oocysts are then multiplicated to complete the cycle. The cycle is then repeated using the multiplicated oocysts. After a total of about three cycles, a final antigen may be harvested and utilized as a source to generate oocysts for a vaccine.
    Type: Application
    Filed: February 21, 2003
    Publication date: September 11, 2003
    Applicant: Wyeth
    Inventor: Frans Gerrit Davelaar
  • Substituted 2-phenyl benzofurans as estrogenic agents
    Publication number: 20030171428
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure 1
    Type: Application
    Filed: December 16, 2002
    Publication date: September 11, 2003
    Applicant: Wyeth
    Inventors: Christopher P. Miller, Michael D. Collini, David H. Kaufman, Robert L. Morris, Robert R. Singhaus, John W. Ullrich, Heather A. Harris, James C. Keith, Leo M. Albert, Rayomand J. Unwalla
  • Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene
    Patent number: 6617334
    Abstract: Compounds of the formula: useful for the treatment of depression and other diseases such as obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disorders caused by ethanol or cocaine abuse and related illnesses.
    Type: Grant
    Filed: January 10, 2003
    Date of Patent: September 9, 2003
    Assignee: Wyeth
    Inventors: Megan Tran, Gary P. Stack
  • Antineoplastic combinations comprising
    Patent number: 6617333
    Abstract: This invention provides the use of a combination of CCI-779 and EKB-569 in the treatment of neoplasms.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: September 9, 2003
    Assignee: Wyeth
    Inventors: Sridhar K. Rabindran, James J. Gibbons, Jr.
  • Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoxaline
    Patent number: 6617327
    Abstract: Compounds of the formula: are useful for the treatment of depression and other diseases such as obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disorders caused by ethanol or cocaine abuse and related illnesses.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: September 9, 2003
    Assignee: Wyeth
    Inventors: Jonathan L. Gross, Gary P. Stack
  • Substituted indenones as estrogenic agents
    Publication number: 20030166643
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure 1
    Type: Application
    Filed: December 11, 2002
    Publication date: September 4, 2003
    Applicant: Wyeth
    Inventors: Robert E. McDevitt, Folake O. Adebi, Heather A. Harris, James C. Keith, Leo M. Albert
  • Methods and compositions useful for the prediction of blood-brain barrier permeation
    Publication number: 20030165813
    Abstract: The present invention provides a method for the in vitro determination of the ability of a compound or a mixture of compounds to permeate the blood-brain barrier and a membrane composition useful therefor.
    Type: Application
    Filed: March 7, 2003
    Publication date: September 4, 2003
    Applicant: Wyeth
    Inventors: Li Di, Edward Harvel Kerns