Patents Assigned to YEDITEPE UNIVERSITESI
  • Patent number: 10794666
    Abstract: A mine sweeping vehicle includes an arm mechanism and a detector integrated to the arm mechanism. The detector scans the underground by an orbital movement. The mine sweeping vehicle includes at least one data recording element for delivering position information of a mine, the position information of the mine is detected by a detector and provided by a positioning system, and the position information of the mine is delivered to a display element.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: October 6, 2020
    Assignee: YEDITEPE UNIVERSITESI
    Inventor: Mehmet Alaeddin Akgun
  • Publication number: 20200230196
    Abstract: A product containing plant derived exosome that may be used in cancer treatment and wound healing. The product enables to provide a low-cost product, which does not cause toxic effects in human body, does not cause damage in the healthy cells during the course of the cancer treatment, does not pose any infection risk since it does not require any procedure such as radiotherapy or surgery, and the side effects occurring in chemotherapy treatment are not experienced. Wheatgrass, garlic and ginger can be used alone or in combination in the product as the plant source.
    Type: Application
    Filed: January 31, 2018
    Publication date: July 23, 2020
    Applicant: YEDITEPE UNIVERSITESI
    Inventors: Fikrettin SAHIN, Merve YILDIRIM, Polen KOCAK, Burge ULUKAN
  • Publication number: 20200061075
    Abstract: A chemotherapeutic drug composition, prepared by combination of Everolimus, one of the drugs used in the treatment of the metastatic renal cell carcinoma (RCC) comprising 2-3% of the malignant tumors, with the anti-apoptotic Bcl-2 inhibitor ABT-737 for the treatment of RCC tumors that developed drug resistance. The effect of Everolimus and ABT-737 drug composition on cell survival and cell death in Everolimus-resistant RCC cell lines overexpressing Bcl-2 protein was shown by in vitro and in vivo experiments and the mechanism of the effect of the drug composition on RCC has been examined from a molecular point of view. Navitoclax (ABT-263), an orally available analog of ABT-737, and other Bcl-2 inhibitors alone or in combination with Everolimus, which is administered once a day at a dose of 10 mg, for the use in the treatment of Everolimus-resistant RCC.
    Type: Application
    Filed: March 1, 2018
    Publication date: February 27, 2020
    Applicant: YEDITEPE UNIVERSITESI
    Inventors: Dilek TELCI, Ayse Hande NAYMAN
  • Publication number: 20200038434
    Abstract: A product containing a boron compound for use in obesity treatment. By means of the present invention, a product can be obtained for obesity treatment which is not toxic to the other tissues and organs of the body. In obtaining the said product, sodium pentaborate pentahydrate, which is a poloxamer derivative, are used.
    Type: Application
    Filed: March 7, 2018
    Publication date: February 6, 2020
    Applicant: YEDITEPE UNIVERSITESI
    Inventors: Fikrettin SAHIN, Nezaket TURKEL SESLI, Aysu YILMAZ
  • Publication number: 20190351059
    Abstract: An antimicrobial (anticandidal, antibacterial, antifungal) and antiviral composition which repels insects such as flies, mosquitoes and ticks. The composition includes poloxamer, boron compound, ethyl butyl acetylaminopropionate and preferably hydrogen peroxide. The present composition is a composition which can be applied in different forms via oral, nasal, ophthalmic, otic, local, ventricle, vaginal, rectal, dermal, intravenous, intramuscular, subcutaneous and intradermal route.
    Type: Application
    Filed: November 8, 2017
    Publication date: November 21, 2019
    Applicant: YEDITEPE UNIVERSITESI
    Inventors: Fikrettin SAHIN, Zeynep IYIGUNDOGDU, Okan DEMIR, Sadik KALAYCI, Binnur KIRATLI
  • Publication number: 20190343886
    Abstract: A composition inhibiting MEIS proteins. The MEIS proteins are effective in proliferation of hematopoietic stem cells. A formulation capable of easily passing through the cell membrane and perform its activity in the cell, and can inhibit MEIS activity in a dose dependent manner. The combination includes isolated cells, medium, growth factors and MEISi inhibitor. The isolated cells are isolated from mouse bone marrow, human bone marrow and human umbilical cord blood. The medium has a pH value of 7.2 and contains bovine serum albumin, recombinant insulin, transferrin, 2-mercaptoethanol and IMDM medium. The growth factors are hematopoietic stem cell factor SCF, fetus liver tyrosine kinase-3 ligand Flt3L, and thrombopoietin. A chemical formula of the MEISi-1 is 4-[2-(benzylamino)-2-oxoethoxy]-N-(2,3-dimethylphenyl) benzamide. A chemical formula of MEISi-2 is 4-hydroxy-N?-[(Z)-(2-oxonaphthalen-1-ylidene)methyl] benzohydrazide.
    Type: Application
    Filed: September 25, 2017
    Publication date: November 14, 2019
    Applicant: YEDÍTEPE ÜNÍVERSÍTESÍ
    Inventors: Fatih KOCABAS, Raife Dilek TURAN
  • Patent number: 10382011
    Abstract: The present invention relates to a capacitance multiplier topology suitable for both positive and negative capacitance multiplication having a minimum configuration consisting of a current feedback amplifier (CFOA), two resistors and a reference capacitor, with each C-multiplier having a respective capacitance amplification constant k which is externally adjustable. Such a capacitance multiplier has less parasitic components, occupies a smaller chip area with higher simulated capacitance value.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: August 13, 2019
    Assignee: YEDITEPE UNIVERSITESI
    Inventor: Ali Umit Keskin
  • Publication number: 20190242678
    Abstract: A mine sweeping vehicle includes an arm mechanism and a detector integrated to the arm mechanism. The detector scans the underground by an orbital movement. The mine sweeping vehicle includes at least one data recording element for delivering position information of a mine, the position information of the mine is detected by a detector and provided by a positioning system, and the position information of the mine is delivered to a display element.
    Type: Application
    Filed: October 11, 2017
    Publication date: August 8, 2019
    Applicant: YEDITEPE UNIVERSITESI
    Inventor: Mehmet Alaeddin AKGUN
  • Publication number: 20190223709
    Abstract: An endomicroscopic device, which, in microsurgical operations, enables the deep surgical sites that cannot be seen from a certain angle to become visible. The endomicroscopic device includes a light source to illuminate the surgical site, a microscope lens for taking and magnifying an image of a tissue at the surgical site, a pair of binocular eyepieces for projecting the image to eyes of the surgeon, an endoscopic probe for displaying blind areas outside of a field of view of the at least one microscope lens from different angles in a periscopic manner, an endoscopic probe outlet, and a distal portion located at an end of the endoscopic probe. The distal portion is flexible and can be angled to be directed to different areas, and provides a second periscopic image.
    Type: Application
    Filed: June 23, 2017
    Publication date: July 25, 2019
    Applicant: Yeditepe Universitesi
    Inventor: Ahmet Hilmi KAYA
  • Publication number: 20190075791
    Abstract: The present invention relates to surfaces which are featured with antimicrobial property. Combinations made with zinc pyrithione, chlorhexidine gluconate and/or triclosan are used in the invention. The invention enables to prevent biodegradation or biocontamination occurring on surfaces. In sectors where surface coating materials are widely used, the pathogen factors (bacteria, yeasts and fungi), which are the causes of surface-borne hygiene, allergy and infectious diseases, are controlled.
    Type: Application
    Filed: October 21, 2016
    Publication date: March 14, 2019
    Applicant: YEDITEPE UNIVERSITESI
    Inventors: Fikrettin SAHIN, Zeynep IYIGUNDOGDU, Okan DEMIR
  • Publication number: 20190030173
    Abstract: The present invention provides a preparation method for a DNA origami based carrier, which essentially comprises the steps of performing multi-functional DNA origami based nanocarrier preparation.
    Type: Application
    Filed: January 22, 2016
    Publication date: January 31, 2019
    Applicant: YEDITEPE UNIVERSITESI
    Inventor: Mustafa CULHA
  • Publication number: 20180351536
    Abstract: The present invention relates to a capacitance multiplier topology suitable for both positive and negative capacitance multiplication having a minimum configuration consisting of a current feedback amplifier (CFOA), two resistors and a reference capacitor, with each C-multiplier having a respective capacitance amplification constant k which is externally adjustable. Such a capacitance multiplier has less parasitic components, occupies a smaller chip area with higher simulated capacitance value.
    Type: Application
    Filed: May 31, 2017
    Publication date: December 6, 2018
    Applicant: YEDITEPE UNIVERSITESI
    Inventor: ALI UMIT KESKIN
  • Patent number: 10125453
    Abstract: The present invention relates to a method of obtaining antifungal, anticandidal and antibacterial textile products. The objective of the present invention is to obtain an antimicrobial product, which enables to reduce the infectious diseases that are transmitted or spread by textile products, reduces extra cost and energy spent for ensuring hygiene, and increases hygienity of disposable textile products. A solution of triclosan, chlorhexidine and disodium octaborate pentahydrate is used in the method of the present invention. The said solution enables the hydrophobic textile products to be transformed into hydrophilic products and thereby enables the antimicrobial agents in the solution to be coded into the textile products.
    Type: Grant
    Filed: August 14, 2014
    Date of Patent: November 13, 2018
    Assignee: YEDITEPE ÜNIVERSITESI
    Inventors: Fikrettin Sahin, Selami Demirci, Okan Demir, Zeynep Ustaoglu
  • Patent number: 10124085
    Abstract: The present invention relates to hygienic products such as sanitary pads and tampons, patient/adult diapers and baby diapers which are made antimicrobial. In the present invention, a mixture of glucopon, chlorhexidine gluconate and triclosan is obtained from the boron compounds called sodium borate, zinc borate, sodium perborate tetrahydrate, borax pentahydrate and disodium octaborate tetrahydrate; and this mixture provides antifungal, anticandidal, antibacterial and antiviral properties to the woven or non-woven textile products and hygienic products. Additionally, the said hygienic products are made hydrophilic by means of the invention.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: November 13, 2018
    Assignee: YEDITEPE UNIVERSITESI
    Inventors: Fikrettin Sahin, Zeynep Ustaoglu, Selami Demirci, Okan Demir, Ayla Burcin Asutay
  • Publication number: 20180318340
    Abstract: The present invention relates to the use of a zeolite as a chemical agent with additional cytotoxic effects used in pleurodesis in the cases of liquid accumulation (pleural effusion) or air accumulation (pneumothorax) in the pleural cavity of lungs.
    Type: Application
    Filed: March 15, 2016
    Publication date: November 8, 2018
    Applicant: YEDITEPE UNIVERSITESI
    Inventors: Ahmet AYDIN, Mohammed CHAREHSAZ, Hande SIPAHI, Gulengul DUMAN, Hayati CELIK, Nurcan BAC, Sina ERCAN
  • Publication number: 20180318206
    Abstract: The present invention relates to a product which prevents hair loss and enables growth of healthy new hair by stem cell application. With the present invention, the newly growing hair is ensured to have the same color with the person's own hair color and thus prevents increase of grey hair. The product of the present invention is comprised of a carrier and active ingredient.
    Type: Application
    Filed: November 1, 2016
    Publication date: November 8, 2018
    Applicant: YEDITEPE UNIVERSITESI
    Inventors: Fikrettin SAHIN, Ozge Sezin SOMUNCU, Pakize Neslihan TASLI, Okan DEMIR
  • Publication number: 20180244895
    Abstract: The present invention relates to composite polymer surfaces which are endowed with antimicrobial and antiviral properties. In the present invention, polymer composites containing additives are obtained, wherein combinations (comprising at least two or more substances) of boron compounds and/or zinc pyrithione made with chlorhexidine gluconate and/or triclosan are used. The invention enables to prevent biodegradation or biocontamination occurring on surfaces. The invention is for controlling the pathogen factors (bacteria, yeasts, fungi and viruses), which are the causes for surface-borne hygiene, allergy and infectious diseases, in sectors (particularly agriculture, health, food and defense) where polymer composites are widely used.
    Type: Application
    Filed: August 16, 2016
    Publication date: August 30, 2018
    Applicant: YEDITEPE UNIVERSITESI
    Inventors: Zeynep IYIGUNDOGDU, Okan DEMIR, Fikrettin Sahin
  • Publication number: 20180127810
    Abstract: The present invention relates to novel bacteria strains that can be used in biological control against mosquito larvae (Cules spp.) and a method of sequence analysis for the strains. The sequence analysis method comprising genomic DNA extracting, 16S rDNA amplification, a PCR amplification of a 550 bp DNA segment and purifying and sequencing of the DNAs obtain via PCR. The protein obtained from a novel Bacillus sphaericus spp. Isolates with the invention is used as larvicide, the step of isolating the protein at product obtaining stage is eliminated. By means of the invention, the bacterial strains (MBI 5, 6, 7) investigated for biological control of mosquitoes are effective in both polluted and fresh water.
    Type: Application
    Filed: October 23, 2017
    Publication date: May 10, 2018
    Applicant: YEDITEPE UNIVERSITESI
    Inventors: Fikrettin SAHIN, Gulengul DUMAN, Munevver Muge ÇAGAL
  • Patent number: D899935
    Type: Grant
    Filed: April 4, 2019
    Date of Patent: October 27, 2020
    Assignee: YEDITEPE UNIVERSITESI
    Inventors: Ahmet Aydin, Ali Bahadir Olcay, Osman Ergin, Esra Özbaş, Ebru Özçelik
  • Patent number: D902034
    Type: Grant
    Filed: April 4, 2019
    Date of Patent: November 17, 2020
    Assignee: YEDITEPE UNIVERSITESI
    Inventors: Ahmet Aydin, Ali Bahadir Olcay, Osman Ergin, Esra Özba§, Ebru Özçelik