Abstract: The invention relates to plant extracts for stimulating the synthesis of hyaluronan synthase, particularly the synthesis of hyaluronan synthase 2 (HAS2). Specific aims of the invention are to increase firmness and/or elasticity and/or tissue moisturization, and/or increase the skin barrier effect, and/or increase tissue resilience, and/or modulate angiogenesis, or the neocreation of blood capillaries, and/or improve healing, and/or cell proliferation, migration or differentiation, and/or skin atrophy, and/or intended to combat the effects of ageing on the skin, and in particular to combat the loss of firmness of the skin observed in the course of ageing, and/or atrophied scars.

Abstract: An instrument (1) for applying a product to superficial epidermal derivatives comprising an elongated core (4) and at least one nucleus (5) supporting an applicator (6) of the product. The core (4), which is twisted, passes through the nucleus (5), and the core (4) and nucleus (5) are connected to prevent the nucleus (5) from pivoting freely on the core (4).

Abstract: An instrument (1) for applying a product such as mascara to epidermal derivatives, comprising an application means (4) for applying the product to the epidermal derivatives, wherein the instrument comprises a twisted plate (5) bearing the application means (4).

Abstract: The invention provides a cosmetic composition for topical use having anti-radical properties and including at least one plant extract of natural origin in a cosmetically acceptable medium, the composition being characterized in that said at least one plant extract of natural origin is insoluble.

Abstract: The invention concerns adult multipotent human stem cells, characterized in that they have: i) significant telomerase activity, ii) an HLA Class I negative phenotype, iii) a normal karyotype, iv) a capacity to become quiescent, v) a capacity for self-renewal preserved for at least 130 population doublings.

Abstract: The invention concerns adult multipotent human stem cells, characterized in that they have: i) significant telomerase activity, ii) an HLA Class I negative phenotype, iii) a normal karyotype, iv) a capacity to become quiescent, v) a capacity for self-renewal preserved for at least 130 population doublings.