Patents Assigned to Zeltiq Aesthetics, Inc.
  • Patent number: 10806500
    Abstract: Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: October 20, 2020
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Leonard C. DeBenedictis, George Frangineas, Jr., Kristine Tatsutani, Linda Pham
  • Patent number: 10765552
    Abstract: Systems for treating a subject's tissue can include a thermally conductive cup, a sealing member, and/or a liner assembly. The systems can include an applicator capable of being reconfigured for a particular treatment site. Components of the applicator can be replaced to achieve a desired configuration. The replaceable components can include contoured heads, liners, and/or sensors. The applicator can draw a vacuum to install various components and/or draw tissue into the applicator. The applicator can cool and/or heat the tissue to affect targeted tissue.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: September 8, 2020
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Austin Root, William Pennybacker, George Frangineas, Clive Heke, Leonard C. DeBenedictis
  • Patent number: 10722395
    Abstract: Application systems, disposable interface assemblies and methods for cooling subcutaneous lipid-rich tissue. One embodiment of an application system includes a cooling unit, a cryoprotectant vessel, a contact member and an array of selectively addressable heating elements. The cryoprotectant vessel is configured to contain a fluidic cryoprotectant such that at least a portion of the cryoprotectant is cooled by the cooling unit to a desired base temperature. The contact member is attached to the cryoprotectant vessel and includes a backside in contact with the cryoprotectant and a front side opposite the backside. The contact member is configured to allow the cryoprotectant to flow from the backside to the front side. The array of selectively addressable heating elements is carried by the contact member.
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: July 28, 2020
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Bryan Weber, Joseph Coakley, John Potosky
  • Patent number: 10682297
    Abstract: A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. The applied substance can include a freezing point depressant and a liposome, an oil-in-water emulsion, a water-in-oil emulsion, or an oil-in-oil emulsion and can be configured to protect or target tissue. The substance and a surface of the skin can be cooled using the applicator to treat acne and other skin conditions.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: June 16, 2020
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Like Zeng, Joel N. Jimenez Lozano, Leonard C. DeBenedictis
  • Patent number: 10675178
    Abstract: A system and method of monitoring, controlling and/or detecting events during the removal of heat from subcutaneous lipid-rich tissue is described. In some examples, the system detects an increase in temperature at a treatment device in contact with the skin of a subject, determines that the increase in temperature is related to a treatment event, and performs an action based on the determination. In some examples, the system shuts off the treatment device, alerts an operator, or reduces the cooling in response to a determined treatment event.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: June 9, 2020
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Mitchell E. Levinson, Jesse Nicasio Rosen, Corydon A. Hinton, Kevin S. Springer
  • Patent number: 10675176
    Abstract: Treatment systems include conformable applicators for performing cryotherapy are described. Aspects of the technology are further directed to methods and conformable applicators capable of affecting target regions. The conformable applicators can be applied a wide range of treatment sites. A strap assembly can hold applicator against the treatment site, and a holder assembly can be adhered to the subject's skin to inhibit, limit, or substantially prevent movement of the applicator along the subject's skin.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: June 9, 2020
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Joseph Coakley, William P. Pennybacker, Bryan J. Weber
  • Patent number: 10575890
    Abstract: Treatment systems, methods, and apparatuses for treating acne, hyperhidrosis, and other skin conditions are described. Aspects of the technology can include cooling a surface of a patient's skin and detecting changes in the tissue. The tissue can be cooled a sufficient length of time and to a temperature low enough to affect glands or other targeted structures in the skin.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: March 3, 2020
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Leonard DeBenedictis, George Frangineas, Jr., Kristine Tatsutani, Bryan J. Weber, Kerrie Jiang, Peter Yee, Linda Pham, Gurvinder Singh Nanda
  • Patent number: 10568759
    Abstract: Systems for treating a subject's tissue can include a thermally conductive cup, a tissue-receiving cavity, and a vacuum port. The vacuum port is in fluid communication with the tissue-receiving cavity to provide a vacuum for drawing the submental tissue, or other targeted tissue, into the tissue-receiving cavity. A thermal device can cool and/or heat the conductive cup such that the conductive cup non-invasively controls the temperature of subcutaneous lipid-rich cells in the tissue. A restraint apparatus can hold a the conductive cup in thermal contact with the target region.
    Type: Grant
    Filed: May 6, 2015
    Date of Patent: February 25, 2020
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Peter Yee, Joseph Coakley, George Frangineas, Jr., Tamara Hilton
  • Patent number: 10555831
    Abstract: A method and system in accordance with particular embodiments includes applying a substance onto skin of a human subject. A method for treating a subject's skin includes applying a hydrogel to the skin which contains the substance. The hydrogel and the skin are cooled using a cooling applicator to treat tissue via the cooling treatment by either freezing or not freezing tissue.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: February 11, 2020
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Joel N. Jimenez Lozano, Leonard C. DeBenedictis
  • Patent number: 10524956
    Abstract: A method and apparatus in accordance with a particular embodiment of the present invention includes applying adhesive onto skin of a human subject. An applicator is then brought into contact with the adhesive such the adhesive is disposed between the applicator and the subject's skin. The applicator is activated to cool a tissue region via the subject's skin, via the heat-transfer surface of the applicator, and via the adhesive. While the tissue region cools, the adhesive also cools, thereby reversibly strengthening adhesion between the subject's skin and the heat-transfer surface and forming a strong bond therebetween. The strengthened adhesion inhibits any movement of the applicator relative to the skin. After cooling the tissue region, the adhesive is warmed, thereby weakening the adhesion which allows the heat-transfer surface of the applicator to be easily separated from the skin.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: January 7, 2020
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Leonard C. DeBenedictis, Like Zeng, George Frangineas, Jr., Joel N. Jimenez Lozano
  • Patent number: 10383787
    Abstract: A treatment device for removing heat from subcutaneous lipid-rich cells of a subject having an actuator that provides mechanical energy to the tissue. The mechanical energy provided may include a vibratory component that can range between low and ultra-high frequencies, and such energy may include various combinations of two or more frequencies tailored to produce the desired effect on the subcutaneous tissue. Disruption of adipose tissue cooled by an external treatment device may be enhanced by applying mechanical energy to cooled tissue. Furthermore, such mechanical energy may impart a vibratory effect, a massage effect, a pulsatile effect, or combinations thereof on the tissue.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: August 20, 2019
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Jesse Nicasio Rosen, Mitchell E. Levinson
  • Patent number: 10292859
    Abstract: A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: May 21, 2019
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Mitchell E. Levinson, Jesse N. Rosen, William P. Pennybacker
  • Patent number: 10201380
    Abstract: Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: February 12, 2019
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Leonard C. DeBenedictis, George Frangineas, Jr., Kristine Tatsutani, Linda Pham
  • Patent number: 10092346
    Abstract: Systems and methods that enable delivery of radiofrequency energy and cryotherapy applications to adipose tissue for reduction and contouring of body fat are described herein. Aspects of the disclosure are directed to methods for reducing surface irregularities in a surface of a subject's skin resulting from an uneven distribution of adipose tissue in the subcutaneous layer. The method can include delivering capacitively coupled or conductively coupled radiofrequency energy to a target region of the subject at a frequency which selectively heats fibrous septae in a subcutaneous layer of the target region to a maximum temperature less than a fibrous septae denaturation temperature. Furthermore, the method can include removing heat such that lipid-rich lobules in the subcutaneous layer are affected while non-lipid-rich cells and lipid-rich regions adjacent to the fibrous septae are not substantially affected.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: October 9, 2018
    Assignee: Zeltiq Aesthetics, Inc.
    Inventor: Mitchell E. Levinson
  • Patent number: 9861421
    Abstract: Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: January 9, 2018
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Michael P. O'Neil, Leonard C. DeBenedictis, George Frangineas, Jr.
  • Patent number: 9861520
    Abstract: Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: January 9, 2018
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Mark William Baker, Joseph Coakley, Paul William Martens, Albert L. Ollerdessen, William Patrick Pennybacker, Jesse N. Rosen, Peter Yee, John W. Allison
  • Patent number: 9844460
    Abstract: A treatment system for cooling subcutaneous lipid-rich cells in a human subject includes an applicator and a control unit. The treatment system has a cooling mode for cooling tissue and a heating mode for warming tissue. The control unit includes a circulation circuit in fluid communication with the applicator, a chiller apparatus configured to chill fluid from the applicator circulation circuit, and a heater apparatus to warmed fluid from the applicator circulation circuit. The control unit mixes the chilled fluid and/or the warmed with fluid in the applicator circulation circuit control the temperature of the fluid circulated in the applicator.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 19, 2017
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Bryan J. Weber, Joseph Coakley, Mark William Baker, Thomas Burnell Reeve, III
  • Patent number: 9844461
    Abstract: Home-use applicators for non-invasively removing heat from subcutaneous, lipid-rich cells via phase change coolants, and associated devices, systems and methods. A device in accordance with a particular embodiment includes an applicator releasably positionable in thermal communication with human skin, and a coolant vessel having a coolant. The device further includes a heat transfer conduit operatively coupled to the applicator and housing a heat transfer fluid that is isolated from fluid contact with the coolant. A heat exchanger is operatively coupled between the coolant vessel and the heat transfer conduit to transfer heat between the heat transfer fluid and the coolant, and a fluid driver is operatively coupled to the heat transfer conduit to direct the heat transfer fluid between the applicator and the heat exchanger.
    Type: Grant
    Filed: January 25, 2011
    Date of Patent: December 19, 2017
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Mitchell E. Levinson, John W. Allison, Joseph Coakley, Bryan Weber
  • Patent number: 9655770
    Abstract: A system is described for removing heat from a subject's subcutaneous lipid-rich regions, such as tissues, organs, cells, and so forth. In various embodiments, the system includes a controller, a computing device, a data acquisition device, a chiller, and one or more applicators. The system can employ these components to receive a selection of a treatment profile and apply the selected treatment using an applicator. The treatment profile may be received from a patient protection device that connects to an applicator.
    Type: Grant
    Filed: August 6, 2013
    Date of Patent: May 23, 2017
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Mitchell E. Levinson, Jesse Nicasio Rosen, Corydon A. Hinton
  • Patent number: D777338
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: January 24, 2017
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Joseph Coakley, William Pennybacker