Patents Examined by A. Louis Monacell
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Patent number: 4038145Abstract: The mixed lymphocyte reaction in tissue culture is used to detect the tumor induced autoimmune reaction which has been found to be characteristic of lymphoid malignancies. Lymphocytes from blood, spleen, and lymph nodes are employed in combinations of two. A mixed lymphocyte reaction from any one of the three possible combinations is indicative of the presence of a lymphoid malignancy.Type: GrantFiled: July 8, 1974Date of Patent: July 26, 1977Assignee: Mead Johnson & CompanyInventor: Richard G. Devlin
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Patent number: 4038435Abstract: The enhancement of foodstuffs is effected by the addition of a small but effective flavor-modifying amount of a compound from the compounds having the general formula ##STR1## wherein, when n is 0, R is hydrogen, methyl, acetyl, ethyl or pyridyl-2; when n is 1, R is hydrogen, methyl, ethyl or acetyl; and, when n is 2, R is hydrogen, methyl, ethyl, acetyl or furfuryl.Type: GrantFiled: June 24, 1974Date of Patent: July 26, 1977Assignee: Firmenich & CieInventors: Max Winter, Fritz Gautschi, Ivon Flament, Max Stoll
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Patent number: 4036697Abstract: A kinetic assay is provided for measuring alpha-amylase content in aqueous solutions. The assay is based on the following reactions:alpha-1,4 linked glucan .sup.alpha-amylase alpha-maltosealpha-maltose + PO.sub.4 .sup.-.sup.-.sup.- .sup.MP Glucose + beta-D-G-1-Pbeta-D-G-1-P .sup.beta-PGM G-6-PG-6-P + NAD .sup.G6PDH 6-P-G + NADHthe concentration of alpha-amylase is determined by measuring the rate of increase in absorbance associated with the production of NADH which is a measure of the activity of alpha-amylase.A novel reagent system is used with the assay and comprises:A polysaccharide having glucose molecules primarily connected through alpha 1,4 linkageMaltose phosphorylase (MP)Phosphate ions (PO.sub.4 .sup.-.sup.-.sup.Type: GrantFiled: February 13, 1976Date of Patent: July 19, 1977Assignee: Beckman Instruments, Inc.Inventors: Kenneth Jonas Pierre, Ker-Kong Tung, Henriette Nadj
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Patent number: 4031250Abstract: An animal or pet food is prepared wherein a red, meaty color is imparted thereto by incorporation of an effective amount of the pigments produced by growth of Monascus purpureus on rice or corn.Type: GrantFiled: November 20, 1974Date of Patent: June 21, 1977Assignee: General Foods CorporationInventors: Gerhard Julius Haas, Edwin Bernard Herman, Joaquin Castro Lugay
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Patent number: 4024290Abstract: The present invention encompasses a bulking agent suitable for incorporating into formulated foods. The bulking agent of the present invention is prepared by condensation of glucose and sorbitol in the presence of an acid-ion exchange resin. The bulking agent of the present invention provides the functions and bulk of about the same weight of sucrose when incorporated into formulated foods. The bulking agent of the present invention is most advantageously used in conjunction with high intensity sweeteners.Type: GrantFiled: March 22, 1976Date of Patent: May 17, 1977Assignee: G. D. Searle & Co.Inventor: Roger M. Layton
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Patent number: 4022667Abstract: A clear, stable aqueous reagent solution comprising a mixture of a water insoluble vinyl ester of an alkyl, alkenyl, or alkyl-aryl carboxylic acid, nonionic detergents, inorganic salts, enzyme activators, and a buffer, which when combined with a suitable acetaldehyde detection system is useful for the analysis of the action of certain carboxylic ester hydrolases.Type: GrantFiled: September 22, 1975Date of Patent: May 10, 1977Assignee: The University of AlabamaInventors: James E. Myrick, Leo M. Hall
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Patent number: 4022919Abstract: A method of removing bitter flavor and pea flavor from a pea flour for addition to food systems comprising the steps of contacting the flour with steam for a time duration sufficient to debitter the pea flavor and cause the steam to take up volatiles and then leading off the steam and volatiles before a substantial cooked pea flavor develops.Type: GrantFiled: November 3, 1975Date of Patent: May 10, 1977Assignee: The Griffith Laboratories, LimitedInventor: Frederick William Comer
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Patent number: 4018910Abstract: The enhancement of foodstuffs is effected by the addition of a small but effective flavor - modifying amount of a compound having the general formula ##STR1## wherein R.sub.1 is hydrogen, an alkyl group or a phenyl group, R.sub.2 is hydrogen, an alkyl group or an acyl group and n is 0, 1 or 2.Type: GrantFiled: June 24, 1974Date of Patent: April 19, 1977Assignee: Firmenich & CieInventors: Max Winter, Fritz Gautschi, Ivon Flament, Max Stoll
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Patent number: 4017363Abstract: Saccharification of 10-20% solid content dextrin solutions for 15-75 hours at amyloglucosidase enzyme dosage levels of 0.3-1.0 AG u/g of solids results in glucose syrups with purity levels exceeding 98%.Glucose purity levels in excess of 98.5% can be achieved if the dextrin solution is formed by enzymatic liquefaction of starch, and saccharification is carried out for 15-25 hours with 0.4-0.8 AG u/g.Type: GrantFiled: December 19, 1975Date of Patent: April 12, 1977Assignee: Novo Industri A/SInventors: William H. McMullen, Rosemary Andino
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Patent number: 4016043Abstract: The present invention relates to improvements in the sandwich technique for the determination of a component of an antigen-antibody reaction in a liquid sample to be tested, utilizing as reagents (a) one component of said reaction bound to the surface of a water-insoluble, water-insuspensible, solid carrier, and (b) a component having the same immunological properties covalently linked to an enzyme. The liquid sample is contacted and incubated with the reagent(s) to form a reaction mixture, the enzyme activity of either the liquid or solid phase of which is a measure of the presence and quantity of the component to be determined. The method is especially useful for diagnostic testing for hepatitis or rubella antibodies.Type: GrantFiled: September 4, 1975Date of Patent: April 5, 1977Assignee: Akzona IncorporatedInventors: Antonius H. W. M. Schuurs, Bauke K. Van Weemen, Gerrit Wolters
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Patent number: 4016302Abstract: The invention provides fat blends e.g. suitable for preparing margarines containing high porportions of palm-based fats, partly in co-randomised form, the fat blends having a ratio of PUP:PPU triglycerides of less than 2.8, the Sa.sub.3 content being greater than P.sub.2 U-8.Type: GrantFiled: September 8, 1975Date of Patent: April 5, 1977Assignee: Lever Brothers CompanyInventors: Hans Robert Kattenberg, Cornelis Poot
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Patent number: 4015025Abstract: The flavor intensity of acetaldehyde and dimethyl sulfide is potentiated by combining the same with a small but effective amount of alginate.Type: GrantFiled: September 24, 1974Date of Patent: March 29, 1977Assignee: General Foods CorporationInventor: Alina Surmacka Szczesniak
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Patent number: 4014747Abstract: A cartridge for a bacteria screening device for detecting and recording the existence of bacteria and other microorganisms in a gaseous medium, such as a hospital operating room atmosphere, arranged to continuously or intermittently expose active culture media to a flow of the gaseous medium to impinge the bacteria and other microorganisms thereon and to thereafter incubate the exposed portions of the culture medium for detection and recording purposes. In the bacteria screening device, different active culture media, responsive to different bacteria, are on opposite surfaces of a strip mounted on supply and take up reels in an enclosed cartridge having apertures forming opposed limited exposure areas for the two sides of the strip. Interleaved with the strip carrying the culture media is a separating strip to prevent contact of exposed surfaces of culture media. The cartridge, designed to contain sufficient culture media for the monitored period of time, e.g.Type: GrantFiled: December 4, 1975Date of Patent: March 29, 1977Inventor: Charles L. Kenyon
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Patent number: 4015026Abstract: A stabilized proteinaceous particle containing either egg or cottage cheese is formed by combining therewith a binder and an amylaceous component. The resultant particle is incorporated in a moist food and is stable under retort canning conditions used to sterilize a moist food.Type: GrantFiled: August 14, 1975Date of Patent: March 29, 1977Assignee: The Quaker Oats CompanyInventors: Morris P. Burkwall, Jr., Carl D. Engstrom, Robert F. Snyder
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Patent number: 4014744Abstract: In processes for measuring glycerides in a fluid, which processes require initial conversion thereof to glycerol, this conversion is achieved according to an improved and simplified saponifying reaction in which a reaction temperature between 35.degree. and 40.degree. C. is used.Type: GrantFiled: January 30, 1975Date of Patent: March 29, 1977Assignee: Miles Laboratories Inc.Inventor: Eppie Sheng Chang
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Patent number: 4015018Abstract: Forage crops such as perennial grasses, alfalfa, corn and sorghum in the wet or moist state are chopped into small pieces, a quantity of a composition consisting essentially of sodium diacetate and dehydrated whey is added, and the resultant mixture is placed in a storage container such as a silo and allowed to ferment to produce silage which is useful as an animal feed, especially for ruminant animals such as beef and dairy cattle.Type: GrantFiled: February 19, 1976Date of Patent: March 29, 1977Assignee: Food Technology ProductsInventors: Elmer F. Glabe, Herbert J. Rebhan
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Patent number: 4014746Abstract: A swab is packaged in a tube having an open end and containing a culture-sustaining liquid at the bottom of a tube, and a plug including a one-way isolating valve located above the liquid and a barrier member forming an air-tight chamber between the plug and the barrier member. After removal of the swab from the tube and swabbing of a body canal or the like with the absorbent tip of the swab, the swab may be placed back in the tube with the absorbent tip adjacent the plug and within the substantially air-tight chamber. The plug may then be forced downwardly through the liquid by pressing on the end of the swab or another rigid member telescoped within the tube so as to force the liquid up through the valve into contact with the absorbent tip. A closure or cap which may be used to press on the end of the stick or the rigid member then forms a seal at the open end of the tube.Type: GrantFiled: June 23, 1975Date of Patent: March 29, 1977Assignee: U.S. Medical Research and Development, Inc.Inventor: Donald J. Greenspan
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Patent number: 4014745Abstract: The susceptibility of bacteria, particularly those derived from body fluids, to antimicrobial agents is determined in terms of an ATP index measured by culturing a bacterium in a growth medium, assaying the amount of ATP in a sample of the cultured bacterium by measuring the amount of luminescent light emitted when the bacterial ATP is reacted with a luciferase-luciferin mixture, subjecting the sample of the cultured bacterium to an antibiotic agent and assaying the amount of bacterial adenosine triphosphate after treatment with the antibiotic by measuring the luminescent light resulting from the reaction, whereby the ATP index is determined from the values obtained from the assay procedures.Type: GrantFiled: April 30, 1975Date of Patent: March 29, 1977Inventors: James C. Administrator of the National Aeronautics and Space Administration, with respect to an invention of Fletcher, Emmett W. Chappelle, Grace L. Picciolo, Hillar Vellend, Stephanie A. Tuttle, Michael J. Barza, Louis Weinstein
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Patent number: 4013515Abstract: 20,798 R.P., which has valuable anti-tumor properties, and acid addition salts thereof are prepared by the microbiological reduction of daunorubicin of the formula: ##SPC1##Or of an acid addition salt thereof, to convert the grouping --CO--CH.sub.3 to --CHOHCH.sub.3.Type: GrantFiled: November 25, 1974Date of Patent: March 22, 1977Assignee: Rhone-Poulenc S.A.Inventors: Jean Florent, Jean Lunel, Jacques Renaut
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Patent number: 4013801Abstract: Edible materials including foods, beverages and oral pharmaceuticals are sweetened by the addition of a sweetening amount in the range of from about 0.002% to 1% by weight (basis edible material) of flavanone represented by the structural formula ##STR1## wherein R is a lower alkyl of from one to three carbon atoms inclusive, n is an integer of from one to three inclusive and M is hydrogen or a physiologically acceptable metal cation.Type: GrantFiled: February 13, 1976Date of Patent: March 22, 1977Assignee: Dynapol CorporationInventors: Daniel J. Dawson, Kenneth M. Otteson, C. Thomas Seitz