Patents Examined by A. Louis Monacell
  • Patent number: 4038145
    Abstract: The mixed lymphocyte reaction in tissue culture is used to detect the tumor induced autoimmune reaction which has been found to be characteristic of lymphoid malignancies. Lymphocytes from blood, spleen, and lymph nodes are employed in combinations of two. A mixed lymphocyte reaction from any one of the three possible combinations is indicative of the presence of a lymphoid malignancy.
    Type: Grant
    Filed: July 8, 1974
    Date of Patent: July 26, 1977
    Assignee: Mead Johnson & Company
    Inventor: Richard G. Devlin
  • Patent number: 4038435
    Abstract: The enhancement of foodstuffs is effected by the addition of a small but effective flavor-modifying amount of a compound from the compounds having the general formula ##STR1## wherein, when n is 0, R is hydrogen, methyl, acetyl, ethyl or pyridyl-2; when n is 1, R is hydrogen, methyl, ethyl or acetyl; and, when n is 2, R is hydrogen, methyl, ethyl, acetyl or furfuryl.
    Type: Grant
    Filed: June 24, 1974
    Date of Patent: July 26, 1977
    Assignee: Firmenich & Cie
    Inventors: Max Winter, Fritz Gautschi, Ivon Flament, Max Stoll
  • Patent number: 4036697
    Abstract: A kinetic assay is provided for measuring alpha-amylase content in aqueous solutions. The assay is based on the following reactions:alpha-1,4 linked glucan .sup.alpha-amylase alpha-maltosealpha-maltose + PO.sub.4 .sup.-.sup.-.sup.- .sup.MP Glucose + beta-D-G-1-Pbeta-D-G-1-P .sup.beta-PGM G-6-PG-6-P + NAD .sup.G6PDH 6-P-G + NADHthe concentration of alpha-amylase is determined by measuring the rate of increase in absorbance associated with the production of NADH which is a measure of the activity of alpha-amylase.A novel reagent system is used with the assay and comprises:A polysaccharide having glucose molecules primarily connected through alpha 1,4 linkageMaltose phosphorylase (MP)Phosphate ions (PO.sub.4 .sup.-.sup.-.sup.
    Type: Grant
    Filed: February 13, 1976
    Date of Patent: July 19, 1977
    Assignee: Beckman Instruments, Inc.
    Inventors: Kenneth Jonas Pierre, Ker-Kong Tung, Henriette Nadj
  • Patent number: 4031250
    Abstract: An animal or pet food is prepared wherein a red, meaty color is imparted thereto by incorporation of an effective amount of the pigments produced by growth of Monascus purpureus on rice or corn.
    Type: Grant
    Filed: November 20, 1974
    Date of Patent: June 21, 1977
    Assignee: General Foods Corporation
    Inventors: Gerhard Julius Haas, Edwin Bernard Herman, Joaquin Castro Lugay
  • Patent number: 4024290
    Abstract: The present invention encompasses a bulking agent suitable for incorporating into formulated foods. The bulking agent of the present invention is prepared by condensation of glucose and sorbitol in the presence of an acid-ion exchange resin. The bulking agent of the present invention provides the functions and bulk of about the same weight of sucrose when incorporated into formulated foods. The bulking agent of the present invention is most advantageously used in conjunction with high intensity sweeteners.
    Type: Grant
    Filed: March 22, 1976
    Date of Patent: May 17, 1977
    Assignee: G. D. Searle & Co.
    Inventor: Roger M. Layton
  • Patent number: 4022667
    Abstract: A clear, stable aqueous reagent solution comprising a mixture of a water insoluble vinyl ester of an alkyl, alkenyl, or alkyl-aryl carboxylic acid, nonionic detergents, inorganic salts, enzyme activators, and a buffer, which when combined with a suitable acetaldehyde detection system is useful for the analysis of the action of certain carboxylic ester hydrolases.
    Type: Grant
    Filed: September 22, 1975
    Date of Patent: May 10, 1977
    Assignee: The University of Alabama
    Inventors: James E. Myrick, Leo M. Hall
  • Patent number: 4022919
    Abstract: A method of removing bitter flavor and pea flavor from a pea flour for addition to food systems comprising the steps of contacting the flour with steam for a time duration sufficient to debitter the pea flavor and cause the steam to take up volatiles and then leading off the steam and volatiles before a substantial cooked pea flavor develops.
    Type: Grant
    Filed: November 3, 1975
    Date of Patent: May 10, 1977
    Assignee: The Griffith Laboratories, Limited
    Inventor: Frederick William Comer
  • Patent number: 4018910
    Abstract: The enhancement of foodstuffs is effected by the addition of a small but effective flavor - modifying amount of a compound having the general formula ##STR1## wherein R.sub.1 is hydrogen, an alkyl group or a phenyl group, R.sub.2 is hydrogen, an alkyl group or an acyl group and n is 0, 1 or 2.
    Type: Grant
    Filed: June 24, 1974
    Date of Patent: April 19, 1977
    Assignee: Firmenich & Cie
    Inventors: Max Winter, Fritz Gautschi, Ivon Flament, Max Stoll
  • Patent number: 4017363
    Abstract: Saccharification of 10-20% solid content dextrin solutions for 15-75 hours at amyloglucosidase enzyme dosage levels of 0.3-1.0 AG u/g of solids results in glucose syrups with purity levels exceeding 98%.Glucose purity levels in excess of 98.5% can be achieved if the dextrin solution is formed by enzymatic liquefaction of starch, and saccharification is carried out for 15-25 hours with 0.4-0.8 AG u/g.
    Type: Grant
    Filed: December 19, 1975
    Date of Patent: April 12, 1977
    Assignee: Novo Industri A/S
    Inventors: William H. McMullen, Rosemary Andino
  • Patent number: 4016302
    Abstract: The invention provides fat blends e.g. suitable for preparing margarines containing high porportions of palm-based fats, partly in co-randomised form, the fat blends having a ratio of PUP:PPU triglycerides of less than 2.8, the Sa.sub.3 content being greater than P.sub.2 U-8.
    Type: Grant
    Filed: September 8, 1975
    Date of Patent: April 5, 1977
    Assignee: Lever Brothers Company
    Inventors: Hans Robert Kattenberg, Cornelis Poot
  • Patent number: 4016043
    Abstract: The present invention relates to improvements in the sandwich technique for the determination of a component of an antigen-antibody reaction in a liquid sample to be tested, utilizing as reagents (a) one component of said reaction bound to the surface of a water-insoluble, water-insuspensible, solid carrier, and (b) a component having the same immunological properties covalently linked to an enzyme. The liquid sample is contacted and incubated with the reagent(s) to form a reaction mixture, the enzyme activity of either the liquid or solid phase of which is a measure of the presence and quantity of the component to be determined. The method is especially useful for diagnostic testing for hepatitis or rubella antibodies.
    Type: Grant
    Filed: September 4, 1975
    Date of Patent: April 5, 1977
    Assignee: Akzona Incorporated
    Inventors: Antonius H. W. M. Schuurs, Bauke K. Van Weemen, Gerrit Wolters
  • Patent number: 4015026
    Abstract: A stabilized proteinaceous particle containing either egg or cottage cheese is formed by combining therewith a binder and an amylaceous component. The resultant particle is incorporated in a moist food and is stable under retort canning conditions used to sterilize a moist food.
    Type: Grant
    Filed: August 14, 1975
    Date of Patent: March 29, 1977
    Assignee: The Quaker Oats Company
    Inventors: Morris P. Burkwall, Jr., Carl D. Engstrom, Robert F. Snyder
  • Patent number: 4014747
    Abstract: A cartridge for a bacteria screening device for detecting and recording the existence of bacteria and other microorganisms in a gaseous medium, such as a hospital operating room atmosphere, arranged to continuously or intermittently expose active culture media to a flow of the gaseous medium to impinge the bacteria and other microorganisms thereon and to thereafter incubate the exposed portions of the culture medium for detection and recording purposes. In the bacteria screening device, different active culture media, responsive to different bacteria, are on opposite surfaces of a strip mounted on supply and take up reels in an enclosed cartridge having apertures forming opposed limited exposure areas for the two sides of the strip. Interleaved with the strip carrying the culture media is a separating strip to prevent contact of exposed surfaces of culture media. The cartridge, designed to contain sufficient culture media for the monitored period of time, e.g.
    Type: Grant
    Filed: December 4, 1975
    Date of Patent: March 29, 1977
    Inventor: Charles L. Kenyon
  • Patent number: 4014745
    Abstract: The susceptibility of bacteria, particularly those derived from body fluids, to antimicrobial agents is determined in terms of an ATP index measured by culturing a bacterium in a growth medium, assaying the amount of ATP in a sample of the cultured bacterium by measuring the amount of luminescent light emitted when the bacterial ATP is reacted with a luciferase-luciferin mixture, subjecting the sample of the cultured bacterium to an antibiotic agent and assaying the amount of bacterial adenosine triphosphate after treatment with the antibiotic by measuring the luminescent light resulting from the reaction, whereby the ATP index is determined from the values obtained from the assay procedures.
    Type: Grant
    Filed: April 30, 1975
    Date of Patent: March 29, 1977
    Inventors: James C. Administrator of the National Aeronautics and Space Administration, with respect to an invention of Fletcher, Emmett W. Chappelle, Grace L. Picciolo, Hillar Vellend, Stephanie A. Tuttle, Michael J. Barza, Louis Weinstein
  • Patent number: 4014744
    Abstract: In processes for measuring glycerides in a fluid, which processes require initial conversion thereof to glycerol, this conversion is achieved according to an improved and simplified saponifying reaction in which a reaction temperature between 35.degree. and 40.degree. C. is used.
    Type: Grant
    Filed: January 30, 1975
    Date of Patent: March 29, 1977
    Assignee: Miles Laboratories Inc.
    Inventor: Eppie Sheng Chang
  • Patent number: 4014746
    Abstract: A swab is packaged in a tube having an open end and containing a culture-sustaining liquid at the bottom of a tube, and a plug including a one-way isolating valve located above the liquid and a barrier member forming an air-tight chamber between the plug and the barrier member. After removal of the swab from the tube and swabbing of a body canal or the like with the absorbent tip of the swab, the swab may be placed back in the tube with the absorbent tip adjacent the plug and within the substantially air-tight chamber. The plug may then be forced downwardly through the liquid by pressing on the end of the swab or another rigid member telescoped within the tube so as to force the liquid up through the valve into contact with the absorbent tip. A closure or cap which may be used to press on the end of the stick or the rigid member then forms a seal at the open end of the tube.
    Type: Grant
    Filed: June 23, 1975
    Date of Patent: March 29, 1977
    Assignee: U.S. Medical Research and Development, Inc.
    Inventor: Donald J. Greenspan
  • Patent number: 4015018
    Abstract: Forage crops such as perennial grasses, alfalfa, corn and sorghum in the wet or moist state are chopped into small pieces, a quantity of a composition consisting essentially of sodium diacetate and dehydrated whey is added, and the resultant mixture is placed in a storage container such as a silo and allowed to ferment to produce silage which is useful as an animal feed, especially for ruminant animals such as beef and dairy cattle.
    Type: Grant
    Filed: February 19, 1976
    Date of Patent: March 29, 1977
    Assignee: Food Technology Products
    Inventors: Elmer F. Glabe, Herbert J. Rebhan
  • Patent number: 4015025
    Abstract: The flavor intensity of acetaldehyde and dimethyl sulfide is potentiated by combining the same with a small but effective amount of alginate.
    Type: Grant
    Filed: September 24, 1974
    Date of Patent: March 29, 1977
    Assignee: General Foods Corporation
    Inventor: Alina Surmacka Szczesniak
  • Patent number: 4013797
    Abstract: An improved process for producing a red color in meat, particularly sausage, using Micrococcus species NRRL-B-8048 alone or preferably in admixture with Lactobacillus plantarum and/or Pediococcus cerevisiae or with other lactic acid producing bacteria is described. Micrococcus sp. NRRL-B-8048 rapidly (in about 4 hours or less) develops the solid bright red color associated with sausage and other fermented and non-fermented meats in the presence of edible nitrate or in the presence of relatively small amounts of added edible nitrite sufficient to more rapidly generate a red color because of NRRL-B-8048. Combinations of the nitrite and nitrate can be used. NRRL-B-8048 can be used to produce processed meats with a red color with a very limited fermentation time (hours) or to produce sausage with a longer fermentation time (days). Micrococcus sp. NRRL-B-8048 is preferably provided in the form of a cell concentrate which is frozen for storage and subsequent thawing for use.
    Type: Grant
    Filed: December 10, 1975
    Date of Patent: March 22, 1977
    Assignee: Microlife Technics, Inc.
    Inventor: Alfred J. Gryczka
  • Patent number: 4013512
    Abstract: A lipid hydrolyzing enzyme-containing substance is brought into contact with an insoluble carrier having a hydrophobic organic compound attached thereto in the form of a hydrophobic residue so that the lipid hydrolyzing enzyme is adsorbed by the hydrophobic residue attached to the insoluble carrier. Then, the lipid hydrolyzing enzyme adsorbed on the carrier is isolated by elution.
    Type: Grant
    Filed: September 18, 1974
    Date of Patent: March 22, 1977
    Assignee: Agency of Industrial Science & Technology
    Inventors: Yoshitsugu Kosugi, Hideo Suzuki, Akira Kamibayashi