Abstract: A composition of chlorogenic acids and method of its use and manufacture in the treatment of metabolic disorders. The composition can be obtained from sunflower seed extract, including Helianthus annulus seeds.

Abstract: A method for extracting S (-)-Oleocanthal from olive oil comprising mixing a first volume of water with a second volume of olive oil to form an olive oil/water mixture; letting the olive oil/water mixture stand; removing an aqueous fraction from the olive oil/water mixture leaving a reduced S (-)-Oleocanthal containing olive oil; and filtering the aqueous fraction to create aqueous S (-)-Oleocanthal.

Abstract: The invention relates to a peptide and saccharide hydrolysate of Theobroma cacao L. (cocoa) beans, to a method for preparing same, to cosmetic compositions containing same, and to cosmetic uses thereof particularly for protecting skin from blue light and/or for combatting the appearance of signs of aging and photoaging of the skin.

Abstract: Disclosed herein are compositions, methods, and systems for treating skin damage or signs of aging in a subject including obtaining whole blood from the subject, collecting platelet rich plasma (PRP) from the whole blood, forming a first topical formulation having the PRP, providing the first topical formulation to the subject for application to an area of skin damage on the subject, providing a second topical formulation to the subject having an activator such that when the second topical formulation is applied to the area of skin damage on top of the first formulation, the PRP is activated and growth factors are released into the area of skin damage. Systems and kits useful in performing the methods are also disclosed.

Abstract: The present disclosure in general relates to a process for (1) reducing impurities, i.e. undesirable natural components such as waxes and undesirable synthetic materials such as agrochemicals and other environmental pollutants, or (2) fractionation of natural components present in an essential oil using at least one selective membrane.

Abstract: The present invention is related to the regulation of the cardiovascular system. In particular, to krill powder compositions and their administration to mammal for regulation of blood pressure.

Abstract: The present invention is directed to a method and a composition for producing and using a plant-based biocidal solution. The plant-based biocidal solution contains a bioactive material and a plant-based substance formed from the cellular material of a plant. The plant-based substance is capable of binding to the bioactive material. In some embodiments, the bioactive material is hydrogen peroxide. The hydrogen peroxide can be added exogenously or generated endogenously. In accordance with further embodiments, the plant-based biocidal solution can be applied to a target, thereby impairing the target. In some embodiments, the target can be a pathogen. In accordance with another embodiment, the plant-based substance of the plant-based biocidal solution can form a microscopic cluster, a complex, or an aggregate for providing sufficient bioactive material to overcome the defense mechanism of the target.

Abstract: The invention concerns a powder feed composition for use as nourishment for bees and for the prevention and treatment of acariosis, and, in particular, of infestation by Varroa destructor, as well as the relative treatment method, comprising: a) nutritional and tonic ingredients, mainly consisting of sugars, lower organic acids, powdered milk and/or algae containing vegetal proteins and yeasts; sugars and lower organic acids; b) natural antioxidants and antiseptics with high activity, contained in the extracts of Crocus sativus, Pelargonium graveolens, Monarda citriodora, Myristica fragrans, Origanum vulgare, Origanum majorana; and c) substances medicinal to bees, comprising at least one of thymol and extracts of Thymus vulgaris, and at least one of oxalic acid, extracts of Aloe vera or Aloe arborescens, geraniol and extracts of Beta vulgaris cv. altissima, and mixtures of two or more of the same.

Abstract: A formula feed for raising pigs with which appetite and body weight can be stimulated in piglets after weaning while decreasing the price, as well as a formula feed for animals, a formula feed for livestock, a formula feed for poultry, a formula feed for pets, and a formula feed for culturing fish. A formula feed characterized in that among a refined powder and a fly powder which are obtained by pulverizing konnyaku (arum root), which is a bulb of a plant, the fly powder is added to the formula feed. The fly powder corresponds to 40 to 50% of the total mass of the fly powder and the refined powder. Further, the formula feed is preferably a formula feed for raising pigs to which at least 1% by mass of the fly powder is added. In addition, 1 to 5% by mass of the fly powder may be added.

Abstract: A topical liniment composition that boost muscle relaxation, increase blood flow, and increase cutaneous delivery of herbal extract that contains polyphenols derived from red chili, black pepper, cinnamon, and turmeric includes a quantity of castor-mineral oil-camphor solution, a quantity of eucalyptus oil, a quantity of clove oil, a quantity of peppermint oil, a quantity of frankincense oil, a quantity of herbal extract concentrate solution, and a quantity of castor oil. Aforementioned ingredients are heterogeneously mixed with each other to formulate the topical liniment composition at standard temperature and pressure (STP). Additionally, a quantity of petroleum jelly and a quantity of beeswax can be heterogeneously mixed with the topical liniment composition to formulate the topical balm composition.

Abstract: The purpose of the present invention is to provide an agent for improving skin looseness or aging caused by dermal cavitation. By attracting fat stem cells into cavities in the dermis, dermal fibroblasts around the cavities can be activated and thus dermal cavitation can be ameliorated. As the results of a screening for fat stem cell attractants, it was found that rosemary extract and licorice extract are capable of attracting fat stem cells and, therefore, can improve skin looseness or aging caused by dermal cavitation.

Abstract: A cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof. The matrix suitable for preparation of cellular or acellular implants for growth and de novo formation of an articular hyaline-like cartilage. A gel-matrix composite system comprising collagen-based matrix having a narrowly defined porosity capable of inducing hyaline-like cartilage production from chondrocytes in vivo and in vitro.

Abstract: Mangosteen nanoparticles and methods of synthesizing Mangosteen nanoparticles are provided. The Mangosteen nanoparticles may be synthesized by drying Mangosteen, Garcinia mangostana fruit, grinding the dried Mangosteen to form powdered Mangosteen, suspending the powdered Mangosteen in a solvent to form a first Mangosteen solution, spraying the Mangosteen solution into boiling water under ultrasonic conditions to form a second Mangosteen solution, resting the second Mangosteen solution at room temperature (about 20° C.), and freeze-drying the second Mangosteen solution to obtain Mangosteen nanoparticles. The drying step may include either air-drying or freeze-drying the Mangosteen. The Mangosteen fruit peel may be used in the drying step instead of the inner Mangosteen fruit. The resulting nanoparticles may be used in pharmaceutical compositions, and may be useful for their antioxidant and antibacterial activities.

Abstract: Compositions comprising an isolate or extract comprising mangiferin, one or more of ferulic acid, Vitamin C, and baicalin, present in amounts sufficient to produce synergistic antioxidant activity and provided for cosmetic and other uses.

Abstract: The invention is directed to a method for the preparation of a multiring engineered heart tissue construct suitable for use in cardiac tissue augmentation and/or replacement therapy. The invention further refers to multiring EHT constructs which comprise at least two force-generating engineered heart tissue rings fused with each other and a device for preparing the same. Finally, the invention relates to force-generating engineered heart tissue rings derived from human cells and their use in drug screening and target validation assays.

Abstract: The invention relates to various compositions for improving exercise performance and/or recovery. The invention also relates to methods of using these compositions and kits including these compositions to improve exercise performance and/or recovery.

Abstract: The present invention relates to a method of manufacturing a water-solubilized solution of mastic gum using a novel solvent system. The water-solubilized solution contains no organic solvent such as ethanol. With the new solvent system, a water-solubilized solution of mastic gum can be prepared with no organic solvents such as ethanol, but with a high amount of mastic gum dissolved therein.

Abstract: A process for producing a distilled ethanol product comprising an antioxidant component and an ethanol component is described. In the process, plant matter containing antioxidants is washed, frozen and exposed to an input volume of ethanol. Antioxidants are ethanolically extracted from the frozen plant matter. The plant matter and the liquid ethanol fractions are then separated and the plant matter having antioxidants extracted therefrom is used to produce ethanol which is subsequently used to extract antioxidants from a second batch of plant matter. The ethanol fraction having antioxidants therein is stored or diluted for later use.

Abstract: The invention relates to the field of minimal residual disease (MRD) diagnostics, which is progressively more applied for the evaluation of treatment effectiveness in patients with a hematological malignancy, such as B-cell precursor acute lymphoblastic leukemia (BCP-ALL), B-cell chronic lymphocytic leukemia (B-CLL), and multiple myeloma (MM). Provided are unique reagent compositions with carefully selected and thoroughly tested combinations of antibodies, for ?8-color flow cytometric stainings as well as for 10-color and 12-color flow cyometric stainings, which can reach sensitivities of at least 10?4, even down to 10?5. Also provided are diagnostic kits and methods for detecting MRD.

Abstract: The presently disclosed subject matter provides fragrance compositions and fragrance combinations that can stimulate the trigeminal system. The compositions and combinations of the presently disclosed subject matter can include both one or more trigeminal-stimulating compounds and one or more additional fragrance compounds. The trigeminal-stimulating compounds can include cooling, warming, and tingling compounds.