Abstract: According to an illustrative embodiment a method to promote healing of a wound is provided comprising contacting the wound with a biologically active composition comprising a lipoic acid derivative and gelatin. In another embodiment a wound dressing is provided comprising a scaffold coated with a biologically active composition comprising a lipoic acid derivative. In a further embodiment, a system is provided for treating a tissue site of a patient, the system comprising a reduced-pressure source to supply reduced pressure, a manifold to distribute reduced pressure to a tissue site and a scaffold coated with a biologically active composition comprising a lipoic acid derivative. Methods for producing such a system and scaffold are also disclosed.

Abstract: A catheter has a double-action retention mechanism with (a) one retention mechanism having a reinforced retention body transformable into a deployed flower-like configuration when the catheter is inserted in the bodily cavity, and (b) a stabilizer securing the catheter to a patient's body to maintain a stable position. The retention mechanism for securing the catheter in the bodily cavity is configured with a thickened or reinforced wall portions of the retention body. The inner channel of the catheter body is wider than conventional catheters, thus attaining better drainage and better fluid flow. Due to the reinforced flower configuration, an inadvertent removal of the catheter with the flower configuration fully deployed will afflict no significant damage.

Abstract: In one embodiment, a catheter pump assembly is disclosed. The catheter pump assembly can include an impeller assembly. A catheter body can be coupled with the proximal end of the impeller assembly, the catheter body having a reduced stiffness section disposed proximally of the impeller assembly. A sheath assembly can be configured to be translate over the catheter body relative to the impeller assembly from an impeller assembly delivery position to an impeller assembly deployment position. When the sheath assembly is in the impeller assembly deployment position, a reduction in stiffness is provided between the distal end of the sheath assembly and the impeller assembly.

Abstract: Ureteral catheters and assemblies are provided including: a drainage lumen including a proximal portion configured to be positioned in at least a portion of a patient's urethra and a distal portion configured to be positioned in a patient's ureter and/or kidney, the distal portion including a coiled retention portion including at least a first coil having a first diameter and a second coil having a second diameter, the first diameter being less than the second diameter; or wherein the retention portion extends radially outwardly from a portion of the distal end of the drainage lumen portion, the retention portion including a proximal end having a first diameter, a distal end having a second diameter, and a wall and/or surface extending therebetween, the retention portion having a second diameter is greater than the first diameter when deployed; or wherein the retention portion includes a plurality of drainage tubes.

Abstract: The present disclosure is directed to a holder. The holder includes a main body, the main body including an interior surface and an exterior surface, a film that extends around at least a portion of the circumference of a first end of the main body and covers an opening of the first end of the main body, and a sheet including a first surface and a second surface, the second surface opposed to the first surface, the first surface operably attached to the seal at at least one point, the sheet configured to extend a distance along an interior of the main body from the first end towards a second end, wherein at least a portion of the first surface of the sheet contacts the interior surface of the main body, and wherein a liquid composition contacts a second surface of the sheet.

Abstract: A body cavity drainage device includes a drainage tube with a distal end configured for insertion into the body cavity of a patient, a fluid outlet at a proximal end of the drainage tube; and an activation apparatus coupled to the drainage tube between the proximal end of the drainage tube and the distal end of the drainage tube. The activation apparatus may be configured to alter a position of the distal end of the drainage tube in response to an input at a control device of the activation apparatus, and a first portion of the drainage tube extending from the activation apparatus toward the distal end may be at least substantially coaxial with a second portion of the drainage tube extending from the activation apparatus toward the proximal end. Methods relate to forming a body cavity drainage devices.

Abstract: A connector-with-integrated-check-valve for minimizing microbial migration to catheter-tubing is formed from three parts: a connector-for-catheter-tubing that is hollow and with an internal valve seat; an elastomer gate (sometimes with disc and stem); and a connector-for-extension-tubing that is hollow and with support-surfaces.

Abstract: A sheathed tubular semi-rigid balloon catheter for performing probing, irrigation, dilation, suction and potential intubation of the nasolacrimal system or paranasal sinus system to treat for stenosis or obstruction. The catheter includes a sheathed tubular probe portion through which a tracer fluid can be injected and through which suctioning of blood or other material can be conducted. The sheath portion of the device can have a distal segment that is inflated in order to dilate parts the nasolacrimal or paranasal sinus system. The high axial load accommodating catheter tool includes a more secure and inexpensively manufactured bond between the metallic semi-rigid tube of the probe portion and the plastic hand-manipulable, multi-connector hub using an enlarged bonding collar.

Abstract: Ureteral catheters and assemblies are provided including: a drainage lumen including a proximal portion configured to be positioned in at least a portion of a patient's urethra and a distal portion configured to be positioned in a patient's ureter and/or kidney, the distal portion including a coiled retention portion including at least a first coil having a first diameter and a second coil having a second diameter, the first diameter being less than the second diameter; or wherein the retention portion extends radially outwardly from a portion of the distal end of the drainage lumen portion, the retention portion including a proximal end having a first diameter, a distal end having a second diameter, and a wall and/or surface extending therebetween, the retention portion having a second diameter is greater than the first diameter when deployed; or wherein the retention portion includes a plurality of drainage tubes.

Abstract: A method for removing fluid from a patient is provided, the method including: deploying a ureteral stent or ureteral catheter into a ureter of a patient to maintain patency of fluid flow between a kidney and a bladder of the patient; deploying a bladder catheter into the bladder of the patient, wherein the bladder catheter comprises a distal end configured to be positioned in a patient's bladder, a drainage lumen portion having a proximal end, and a sidewall extending therebetween; and applying negative pressure to the proximal end of the bladder catheter to induce negative pressure in a portion of the urinary tract of the patient to remove fluid from the patient. Systems and kits related thereto also are provided.

Abstract: A method for filling and venting a device for extracorporeal blood treatment is disclosed, such as a patient module in a heart-lung machine, without attached patient. A filling liquid from a filling liquid container located higher than the device flows by gravity via a venous side of the system into a reservoir and flows onwards into a blood pump located at the lower end of the reservoir, wherein a first controllable valve (HC1) for a venting line of a filter is opened and, after the response of an upper filling level sensor in the reservoir, is closed. An upper level of the filter is positioned higher than the upper filling level sensor, and a start-stop motion of the blood pump is performed, as a result of which a stepped flooding of the filter is made providing for an advantageous de-airing of the device.

Abstract: A ureteral catheter for placement in a kidney, renal pelvis, and/or in a ureter adjacent to the renal pelvis of a patient, includes: an elongated tube having a proximal end, a distal end, and a sidewall extending between the proximal end and the distal end of the tube defining at least one drainage lumen extending through the tube; and an expandable retention portion configured to transition from a retracted position to a deployed position and which, in the deployed position, defines a three-dimensional shape positioned to maintain fluid flow from the kidney through at least the distal end of the tube.

Abstract: Various embodiments of the present invention provide a conduit device including an attaching device configured for defining a helical pathway through a tissue wall and complementary ring in cooperation for securing the device within an aperture defined in the tissue wall. Some embodiments of the present invention further provide a system for implanting a conduit device in a tissue wall. More specifically, some embodiments provide a system including a coring device for defining an aperture in a tissue by removing and retaining a tissue core and securely implanting a conduit device therein so as to provide fluid communication between a first and second surface of the tissue wall via the conduit device.

Abstract: Embodiments described herein generally relate to improved devices, systems, kits, products and methods related to topical medicament application of measured dosages. The kits and devices can single use and/or disposable for example.

Abstract: A medical suction apparatus may include a wand having a proximal end and a distal end. The apparatus may further include a lumen defined within the wand, the lumen configured to couple to a suction source. The apparatus may also include a mouth defined at the distal end of the wand and placing the lumen in communication with an exterior of the wand, where the mouth has an upper edge and a lower edge, where the mouth is elongated horizontally between the upper edge and the lower edge, and where at least the upper edge or the lower edge is beveled to enable scraping of a surface.

Abstract: Methods of declotting vascular access technologies, such as vascular access assemblies that facilitate hemodialysis, are provided. The methods can include disposing a catheter within a patient to access a vascular access assembly within the heart of the patient. The catheter can be coupled to the vascular access assembly such that a clot can be evacuated from within the vascular access assembly via the catheter.

Abstract: An insertion aid for catheter manipulation is disclosed. The insertion aid can be used for urinary catheters, such as hydrophilic urinary catheters for intermittent use. The insertion aid includes first and second plate-like arms arranged overlying each other and with a separation distance there between. The insertion aid also includes a resilient hinge connecting adjacent marginal edges of the plate-like arms together. At least one of the plate-like arms includes a groove on its clamping inner surface for holding a catheter shaft. The groove extends at least partly in the same direction as, and essentially parallel to, the resilient hinge, and is arranged at a distance both from the resilient hinge and from the marginal edge of the plate-like arm. Corresponding catheter set and catheter assembly are also disclosed.

Abstract: A container for a medical liquid, comprising a connection piece via which a medical liquid can be pumped into or out of the container, an attachment part which can be attached to the connection piece and connected to a pump device to pump a medical liquid or out of the container, and a sealing element for sealing a passage between the connection piece and the attachment part. The sealing element has a slot opening which is closed against a liquid flow when the pump device is not attached to the attachment part and which is open when the pump device is attached to the attachment part such that a medical liquid can be pumped through the slot opening. The attachment part has a connection portion with an opening into which the connection piece can be inserted along an insertion direction in order to connect to the attachment part.

Abstract: A connector for use with a pleural catheter that connects securely a drainage tube to a valve of the plural catheter. A system including a fluid receptacle having a negative fluid pressure, a plural catheter having an end designed for implantation into a pleural space of a subject, and an opposite second end having a valve feature, a drainage tube having an end connected to the fluid receptacle and another end having a connector that securely connects the drainage tube to the valve feature of the catheter.

Abstract: A surgical drain device includes an adhesion matrix of biodegradable polymer material and a plurality of drain tubes attached to the matrix. The device is implanted within a surgical wound to treat the presence of seromas, for example, and is used to promote drainage, tissue adhesion, and wound closure. The drain tubes converge into a common collection tube that leads wound fluid outside the body under gravity feed or negative pressure applied to the collection tube. The matrix contains an array of apertures that allow tissue contact across the device. The device also can include a coating of surgical adhesive and a tissue anchoring system of hooks or barbs. The device can be used with a negative pressure system to further improve the drainage band can also be used with a wound dressing. The device and systems containing the device are particularly useful to promote the healing of surgical wounds from abdominal surgery.