Abstract: The present disclosure relates to a bioelectrical signal acquisition device, an interactive system, and related methods. The bioelectrical signal acquisition device includes a series of electrodes that are configured and positioned to effectively record bioelectrical signals from a user's head. The interactive system and related methods can be used to collect, display, and analyze the bioelectrical signals, especially signals related to sleep. The device, system, and methods can also be applied to modulate physiological or pathological conditions of the user.

Abstract: A system for providing stimulation to a patient includes one or more processors implemented in circuitry and one or more accelerometers configured to generate one or more accelerometer signals. The one or more processors are configured to determine accelerometer information for a medical device associated with the patient based on the one or more accelerometer signals and convert the accelerometer information into frequency domain coefficients. The one or more processors are further configured to determine an activity level for the patient based on the frequency domain coefficients and determine one or more stimulation parameters based on the activity level. The one or more processors are further configured to output electrical stimulation to the patient based on the one or more stimulation parameters.

Abstract: The present disclosure relates to guidewire devices with an outer tube and a core. The distal section of the core extends into and is surrounded by the outer tube. One or more centering mechanisms are also disposed within the outer tube and are arranged to fill a portion of the annular space between the core and the inner surface of the tube. The one or more centering mechanisms thereby assist in keeping the distal section of the core axially aligned within the tube, which enables effective control of the device and minimizes undesirable whip movements of the guidewire.

Abstract: A prick test kit comprises a bottom tray containing a plurality of wells disposed in an array, wherein each of the wells contains a vial of a small amount of a specific well associated antigen, with each well and associated vial having a different antigen disposed therein, each of the vials having a rubber cap disposed thereon that is sterile and able to be pricked by a needle such that the small amount of antigen can be removed therefrom. A penetrating plate is disposed above the wells and having on the lower surface thereof diametrically opposite from the vials in the wells a plurality of piercing needles, one associated with each of the wells and directed downward there to but not touching any of the files. A separating plate is disposed between the bottom tray and the penetrating plate. A sterile covering is provided for containing the entire assembly.

Abstract: A device may comprise a work element, an outer tube co-axially disposed around a portion of the work element and a collar assembly. The work element may be configured to rotate and define proximal and distal ends, and may comprise a body portion, one or more articulable beak(s) configured to cut tissue, and a beak actuation portion. The collar assembly may be coupled to the work element away from the articulable beak(s), and may comprise a distal collar element coupled to the body portion, a middle collar element coupled to the outer tube and a proximal collar element coupled to the beak actuation portion. The distal collar element may comprise a first peripheral surface that extends around the distal collar element and that faces the proximal end and the middle collar element may comprise a second peripheral surface that that extends around the middle collar element, faces the distal end and at least partially contacts the first peripheral surface.

Abstract: Systems configured to acquire temperature signals from an Abreu Brain Thermal Tunnel (ABTT), to analyze the temperatures signals, and to determine a condition of a human body from the analysis, and a method for doing the same, are described. In addition, systems for application of thermal signals to the ABTT for treatment of conditions are described.

Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes, and associated architectures, as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.

Abstract: The automated allergy office system and method takes a medical professional through an allergy testing process and a follow-on immunology injection process step-by-step using LED computer screen tables, computer tablets, smart phones, an internal office computer system accessing Patient medical records, and an augmenter reality headset. The augmented reality headset technology and artificial intelligence are layered onto an improved manual system to minimize false positives and negatives, to improve the patient experience patient, resulting in cost savings for the doctor and patient and enabling portions of the allergy testing to be performed remotely from the office of the allergist, either by the patient or by a trained medical technician.

Abstract: A blood pressure monitoring device configured to attach and supply air to a blood pressure cuff can include a housing having an interior, a port configured to enable fluid communication between the interior of the housing and an interior of the blood pressure cuff, and an air intake configured to allow ambient air to enter the interior of the housing and further configured to inhibit liquids from entering the interior of the housing. The air intake can define a non-linear passageway for ambient air to enter the interior of the housing. The housing can have a first side and a first inner wall. The air intake can be defined by a first opening in the first side and a second opening in the first inner wall. The first opening can be not aligned with the second opening.

Abstract: Arrangements are provided including a base having a bore disposed therein extending from a first surface of the base through a second surface of the base, a fluid transport tube having a first end, a second end opposite the first end, and a lumen having an inner diameter, at least the second end of the tube being received within the bore of the base, and at least one fluid transport enhancing groove having at least a first section disposed in the second surface of the base and in fluid communication with the bore.

Abstract: Disclosed herein are system, method and/or device embodiments for using a wireless mouthguard with pressure sensors for measuring bite compression forces generated by a bruxism patient during sleep. A system comprises a mouthguard and a microelectromechanical system (MEMS) coupled to a portion of the mouthguard covering an axial plane of a tooth. The MEMS comprises an antenna, a capacitive sensor, a microcontroller, and a power supply. The sensor generates sensor signals corresponding to a force generated by a mouthguard wearer's bite. The MEMS may then transmit data describing the wearer's bite force over a period of time to an external computing device for display and analysis.

Abstract: Disclosed is a method, a headset and a system for determining heart rate data of a user.

Abstract: A method of monitoring depth of muscle relaxation of a patient includes applying a series of stimulations to a nerve of a patient and measuring muscle responses thereto. A maximal stimulus current, a supramaximal stimulus current, and/or a submaximal stimulus current are determined based on the muscle responses, wherein the maximal stimulus current is a current at which a maximal muscle response is produced from stimulating the nerve, the supramaximal stimulus current is greater than or equal to the maximal stimulus current, and the submaximal stimulus current is less than the maximal stimulus current. A first set of stimulations are applied to the nerve of the patient. Either the supramaximal stimulus current or the submaximal stimulus current are then selected for a subsequent series of stimulations based on the measured muscle responses to the first series of stimulations, and the subsequent series of stimulations are performed accordingly to monitor the patient's depth of muscle relation.

Abstract: A blood pressure measurement device includes an outer case; a base; a pump provided on the base such that the pump is shifted from a center of the outer case and located on one side as viewed in a circumferential direction of a living body; a drive unit provided on the base and located on one side of the pump as viewed in a direction orthogonal to the circumferential direction; an on-off valve provided on another side of the pump as viewed in the direction orthogonal to the circumferential direction; a pressure sensor provided on said another side of the pump as viewed in the direction orthogonal to the circumferential direction; and packing provided between the on-off valve and the pressure sensor and the base.

Abstract: A blood pressure measurement device includes an outer case; a base; a pump provided on a surface of the base such that the pump is shifted from a center of the outer case and located on one side as viewed in a circumferential direction of a living body; a first pressure sensor and a second pressure sensor that are provided such that the first pressure sensor and the second pressure sensor are arranged side by side in the circumferential direction and located on one side as viewed in a direction orthogonal to the circumferential direction; and a first on-off valve and a second on-off valve that are provided such that the first on-off valve and the second on-off valve are arranged side by side in the circumferential direction with reference to the first pressure sensor and the second pressure sensor.

Abstract: Disclosed is an analyte measuring patch for invasive measuring a concentration of an analyte, in particular glucose. The analyte measuring patch includes a sensor with a working electrode (101), a counter electrode (103) and a reference electrode 102). The patch further includes an electronics unit with a microcontroller (1200) and a current measurement unit. The microcontroller (1200) includes a control output (DAC), a first analogue input (ADC-1) and a second analogue input (ADC-2). The control output (DAC) is operatively coupled with a control electrode, the control electrode being either of the working electrode or (101) or the counter electrode (103). The first analogue input (ADC-2) is operatively coupled with a measurement electrode via the current measurement unit, the measurement electrode being either of the working electrode (101) or the counter electrode (103). The second analogue input (ADC-1) is operatively coupled with the reference electrode (102).

Abstract: A guidewire comprises a core shaft, a coil body covering a distal end portion of the core shaft, and a coating agent covering an outer periphery of the coil body, wherein the coil body includes a distal coil body disposed on a distal side of the coil body, and a proximal coil body disposed on a proximal side of the distal coil body, a surface roughness of the proximal coil body is higher than a surface roughness of the distal coil body.

Abstract: Devices, systems and methods that track various aspects of a person's sleep and environment to optimize one or more aspects of the user's environment and sleep conditions, quality and duration, together or alone, and help make the one or more users maintain and prolong his or her deep sleep status and improve the their sleep duration and quality.

Abstract: An allergen delivery system with a tray and delivery set. The delivery set includes a dispensing well. The dispensing well holds a wettable material to receive an allergen and provide it to a delivery barb that has been received into the dispensing well. A conduit is connected to the dispensing well, to receive the allergen and provide it to the dispensing well. A reservoir is connected to the conduit to receive the allergen and provide it to the conduit. A cap is disposed on the reservoir, with a hole, such that when a finger depresses the cap, the finger covers the hole and the depression creates pressure within the reservoir, which motivates an amount of the allergen to flow out from the reservoir through the conduit and into the dispensing well, to be absorbed by the wettable material, where the allergen is available for delivery to the barbed delivery applicator.

Abstract: Techniques (methods and devices) for neural stimulation through audio with dynamic modulation characteristics are disclosed. The techniques include receiving a mapping of sensor-input values and modulation-characteristic values, wherein each sensor-input value corresponds to a respective modulation-characteristic value; receiving an audio element from an audio source, wherein the audio element comprises at least one audio parameter; identifying an audio-parameter value of the audio parameter; receiving a sensor-input value from a sensor; determining a sensor-input value based on the sensor-input value; selecting from the mapping of sensor-input values and modulation-characteristic values, a modulation-characteristic value that corresponds to the sensor-input value; generating an audio output based on the audio-parameter value and the modulation-characteristic value; and playing the audio output.