Abstract: The present invention concerns a method for the detection of distortion products of otoacoustic emissions (DPOAE), comprising the steps: (a) output of at least one first pair of primary tones each consisting of a first primary tone with frequency f1,1 and sound pressure level L1,1 and a second primary tone with frequency f2,1 and sound pressure level L2,1 with f2,1>f1,1, and (b) detecting evoked distortion products of otoacoustic emissions (DPOAE), characterized in that the first primary tone {f1,1, L1,1} is output with a time delay tlag after the second primary tone {f2,1, L2,1}.

Abstract: Devices and techniques for continuously monitoring pressure and simultaneously monitoring changes in blood flow, vascular resistance, and/or vascular behavior are provided. The techniques are employed in measuring intracranial pressure (ICP), while simultaneously measuring cerebral blood flow and/or cerebrovascular resistance or behavior. A sensor device includes an optical and piezoelectric sensing assembly integrated into a deployable ICP monitoring device.

Abstract: A blood pressure measurement module is provided and includes a base, a valve plate, a top cover, a micro pump, a driving circuit board and a pressure sensor. The valve plate is disposed between the base and the top cover. The micro pump is disposed within the base. The pressure sensor is disposed on the driving circuit board. An air inlet groove and the pressure sensor are connected to an airbag. The micro pump is actuated to make the airbag be inflated and oppress the skin of a user. The pressure sensor detects the pressure change within the airbag to measure the blood pressure of the user.

Abstract: An apparatus includes a drive module having a drive module base component and a load-sensed component. An elongated medical device (EMD) is removably coupled to an isolated component. The isolated component is isolated from an external load other than an actual load acting on the EMD. The isolated component is removably coupled to the load-sensed component. A load sensor is secured to the drive module base component and the load-sensed component sensing the actual load acting on the EMD.

Abstract: A medical chair is provided for conducting and controlling in-depth medical exams from a remote location. Specifically, the medical chair allows for providing remote diagnoses and treatment, including a variety of testing procedures for patients with nonemergent but time sensitive illness or injury. The medical chair can be used in a semi-permanent, permanent, temporary, or mobile environment and includes stabilizing assemblies to adapt to any of these environments.

Abstract: A breathing-driven flexible respiratory sensor includes: a test cavity and a digital electrometer, wherein an upper internal wall of the test cavity is provided with an upper detecting component, and a lower internal wall of the test cavity is provided with a lower detecting component; the upper detecting component and the lower detecting component is arranged in a longitudinal symmetry form; wherein the upper detecting component comprises a substrate, an electrode and a gas sensitive film bonded in sequence from top to bottom, and the substrate is bonded to the upper internal wall of the test cavity; wherein a rubber airbag is disposed in the test cavity, and a friction film is bonded to the rubber airbag; an air inlet cylinder is connected to a left end of the rubber airbag, and an air outlet cylinder is connected to a right end of the rubber airbag.

Abstract: An electrochemical sensor for humoral detection and a detection device. The electrochemical sensor for humoral detection includes a material layer including at least one hydrophilic region; and at least one detection unit, located in the hydrophilic region. The hydrophilic region includes a sampling port configured to be in contact with a liquid sample (for example, saliva) to be detected, the detection unit includes a working electrode and an opposed electrode disposed apart from each other, the working electrode comprises a reaction surface containing a substance configured to have a reaction with an analyte in the liquid sample, and the working electrode and the opposed electrode are configured to detect an electrical signal generated by the reaction so as to detect the analyte.

Abstract: A method, apparatus and computer program wherein the method comprises: identifying a plurality of extrema points in a detected biosignal; comparing the identified extrema points with a plurality of sets of reference points wherein different sets of reference points correspond to different frequencies of the biosignal; and identifying the set of reference points that most closely fit the identified extrema points to determine a frequency of the biosignal.

Abstract: A method for determining the focus of the visual attention of an individual from electroencephalographic signals. At least one visual stimulus to be displayed is generated from at least one graphical object, a visual stimulus being an animated graphical object obtained by applying to a graphical object a temporal succession of elementary transformations that is temporally parameterized by a corresponding modulation signal. From a plurality of electroencephalographic signals produced by the individual focusing his visual attention to one of the visual stimuli, a modulation signal is reconstructed. A visual stimulus corresponding to the modulation signal for which the degree of statistical dependence with the reconstructed modulation signal is higher than a first threshold is identified.

Abstract: An apparatus for non-invasively estimating blood pressure is provided. Thee apparatus for estimating blood pressure may include a bio-signal measurer configured to measure a bio-signal from a user and a processor configured to estimate blood pressure using the measured bio-signal. The processor may extract a first feature and a second feature from the bio-signal at an extraction time, estimate changes in the first feature and the second feature which have occurred during a time period from a calibration time at which the first feature and the second feature are calibrated to the extraction time at which the first feature and the second feature are extracted, and estimate a blood pressure based on the changes in the first feature and the second feature.

Abstract: The disclosure provides a dynamic interaction-oriented subject's limb time-varying stiffness identification method and device. The method includes: the combination of subject's limb displacement and measured force data or the combination of angle and measured torque data is collected; based on the time-varying dynamic system constructed based on a second-order impedance model, the linear parameter varying method is utilized to substitute the time-varying impedance parameters and reconstruct the restoring force/torque expression; iterative identification is performed on variable weights, dynamic interaction force/torque, and restoring force/torque by using time-varying dynamic parameters based on the dynamic interaction force/torque expression expanded from basis function; the time-varying stiffness is solved by using variable weights and dynamic interaction force/torque according to expression with substituted the time-varying impedance parameters.

Abstract: A multiple test applicator has a first and second scratching barb in cooperative engagement with each other and a first and second reservoir in a fluid tray each filled with a first and second allergen. During allergen loading, the first allergen is loaded onto the first scratching barb as the second allergen is loaded onto the second scratching barb. Then, during allergen deposition the applicator is removed from the fluid tray and the first scratching barb moves laterally across the patient's skin as the second scratching barb moves laterally across the patient's skin toward the first scratching barb. The first scratching barb then scratches the epidermis at a first test site as a trace amount of the first allergen is deposited into a first site as the second scratching barb scratches a second site as a trace amount of the second allergen seeps into the second site.

Abstract: A gait evaluation apparatus that evaluates a training gait of a paralyzed patient suffering from paralysis in a leg includes an acquisition unit configured to acquire a plurality of motion amounts of a paralyzed body portion according to a gait motion and an evaluation unit configured to evaluate that the gait motion is an abnormal gait in a case where at least one of the motion amounts acquired by the acquisition unit meets any one of a plurality of abnormal gait criteria set in advance. The abnormal gait criteria include at least two or more first criteria, which are criteria relevant to motion amounts of different parts of the paralyzed body portion, or at least two or more second criteria, which are criteria relevant to motion amounts of the same part of the paralyzed body portion in different directions.

Abstract: A method for determining the focus of the visual attention of an individual from electroencephalographic signals. At least one visual stimulus to be displayed is generated from at least one graphical object, a visual stimulus being an animated graphical object obtained by applying to a graphical object a temporal succession of elementary transformations that is temporally parameterized by a corresponding modulation signal. From a plurality of electroencephalographic signals produced by the individual focusing his visual attention to one of the visual stimuli, a modulation signal is reconstructed. A visual stimulus corresponding to the modulation signal for which the degree of statistical dependence with the reconstructed modulation signal is higher than a first threshold is identified.

Abstract: Systems, devices, apparatus, methods, and computer-readable storage media for developmental assessment using eye tracking are provided. In one aspect, a system for development assessment via eye tracking includes: a patient-side computing device having a screen for presenting visual stimuli to a patient, an eye-tracking device integrated with the patient-side computing device and configured to collect eye-tracking data of the patient while the visual stimuli are presented to the patient on the screen of the patient-side computing device, and an operator-side computing device configured to present a user interface for an operator to communicate with the patient-side computing device.

Abstract: An evaluating apparatus of this application includes a detector configured to detect a biological signal of a user, and a controller configured to calculate an amount of activity of the user from the biological signal, determine whether the user is sleeping during a first period by comparing the amount of activity with a low threshold, and determine whether the user is sleeping during a second period after the first period by comparing the amount of activity with a high threshold, the low threshold being lower than the high threshold.

Abstract: There is provided herein a motion-based evaluation of reaction time that utilizes motion detection hardware of a mobile device to determine auditory and visual stimulated reaction time. In an embodiment, the subject holds a mobile computing device equipped with built-in triaxis accelerometer and gyroscope with both hands at arms length away from the face. A visual or auditory stimulus is then presented on screen via a software application that also records the response time for the individual to initiate a movement of the device. A simple reaction time test could include the movement of the device in any direction that exceeded a threshold of movement beyond what would be expected from static holding. An embodiment of a choice reaction time test would provide for specific directional movements as it related to an instructed stimulus.

Abstract: A stimulus is displayed in a visual field on a stimulus side (e.g., right or left) of a subject. An input is received from an input side of the subject. Where the input side is contralateral to the first stimulus side, a crossed reaction time is determined as a span of time between displaying the stimulus and receiving the input. Where the input side is ipsilateral to the stimulus side, an uncrossed reaction time is determined as a span of time between displaying the stimulus and receiving the input. A crossed-uncrossed difference time can be determined as a difference between the crossed reaction time and the uncrossed reaction time. The crossed reaction time, the uncrossed reaction time, and/or the crossed-uncrossed difference time can be used to determine a severity of Traumatic Brain Injury of the subject.

Abstract: The blood pressure measuring device includes a device main body configured to form a flow path of a fluid and supply the fluid, and a cuff to be wound around a living body, the cuff provided with a bag-shaped connection portion with an opening and a connection plate with a hole communicating with the opening; the connection portion formed of a sheet member; the connection plate having a bending elastic modulus higher than that of the connection portion, bonded to the connection portion and adhered to the device main body; and the cuff configured to be inflated when the fluid is supplied to an internal space of the cuff.

Abstract: Disclosed are self-powering biofuel cell and sensor devices, systems and techniques. In some aspects, a self-powered biosensing system includes an electronic circuit; an anode including an enzymatic layer electrically coupled to a power supply voltage terminal of the electronic circuit and configured to interact with an analyte in a fluid, such as glucose or lactate; and a cathode electrically coupled to a ground voltage terminal of the electronic circuit, where the electronic circuit is operable to control and use the electrical energy generated at the anode and cathode for powering the biosensing system and detecting a concentration of the analyte in the fluid.