Patents Examined by Amber R Stiles
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Patent number: 11744611Abstract: The invention relates to a puncture system having an outer tubular body which is designed to remain in a body part of a living being, said puncture system comprising at least one inner tubular body and a puncture needle, wherein the inner tubular body is guided through a working lumen of the outer tubular body and is longitudinally displaceable relative to the outer tubular body, and the puncture needle is guided through a puncture lumen of the inner tubular body and the inner tubular body is longitudinally displaceable relative to the puncture needle. The puncture system has a manually actuatable element that can be moved by manual actuation at least into a fixing position and into a release position, wherein, in the fixing position, the longitudinal displaceability a1) of the inner tubular body relative to the outer tubular body and/or a2) of the puncture needle relative to the inner tubular body and/or a3) of the puncture needle relative to the outer tubular body is removed or reduced.Type: GrantFiled: January 24, 2019Date of Patent: September 5, 2023Inventor: Jens Ebnet
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Patent number: 11737973Abstract: The present invention relates to a composition for preparing a microneedle, a soluble microneedle, and a microneedle percutaneous patch comprising the soluble microneedle. A soluble microneedle contained in a microneedle percutaneous patch of the present invention has a high drug loading capacity and excellent strength and thus may contain an effective amount of donepezil or a pharmaceutically acceptable salt thereof even with a small area of the microneedle. Accordingly, the present invention is economical and produces a lower level of skin irritation.Type: GrantFiled: May 16, 2018Date of Patent: August 29, 2023Assignee: Raphas Co., Ltd.Inventors: Tae Hyung Kim, Booyong Lee, Jung Dong Kim, Do Hyeon Jeong, Dongchul Shin, Yongyoun Hwang, Yun-Sun Nam, Joo Han Lee, Eun Jin An
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Patent number: 11738185Abstract: An in-plane metal microneedle array and a manufacturing method therefor is disclosed. A large-size metal sheet is cut into small metal sheets. Inner sides of the upper and the lower cover plates of the tooling are provided with grooves matched with the sizes of the small metal sheets. Through holes are formed at edges around the cover plates. The metal sheets are placed in the grooves and fastened through bolts. The geometry and the size of a sheet microneedle array are designed, and a CAD model of the plane microneedles is built. A wire path is cut according to the CAD model. A few materials are reserved on both sides of substrates of the microneedle array without cutting. The unprocessed parts on both sides of the microneedle substrate are cut to obtain an in-plane metal microneedle array with a plurality of microneedle bodies.Type: GrantFiled: May 13, 2019Date of Patent: August 29, 2023Assignee: DALIAN UNIVERSITY OF TECHNOLOGYInventors: Guojun Ma, Chengwei Wu, Yuting Niu, Wei Zhang, Yongtao Lv, Xiao Han, Jianli Ma
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Patent number: 11737644Abstract: A device and method for treating disease involves inserting a scope into a patient's body, the scope having a light source, a camera and a cartridge connected thereto. The cartridge has two chambers separated by membrane, a first one of the chambers containing a virus, and a second one of the chambers being connected to a plurality of microneedles configured for extending into the patient's tissue upon insertion of the scope. Cells from the patient are removed via suction from the microneedles and are deposited in the second chambers. The membrane is then broken to mix the virus with the cells to infect the cells, and the infected cells are then transported back into the patient to treat the disease.Type: GrantFiled: March 16, 2018Date of Patent: August 29, 2023Inventor: Donald Spector
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Patent number: 11737687Abstract: Methods, apparatuses, and systems are provided for determining whether to administer a medication dose as a single dose or whether to fractionate the single dose to be administered as at least two discrete doses. Embodiments include determining a first analyte level and a first rate of change of the analyte level; determining an initial medication dose based on one or more anticipated subsequent medication doses, the first analyte level relative to an analyte level threshold, and the first rate of change of the analyte level relative to a rate of change threshold; administering the initial medication dose; determining a second analyte level and a second rate of change of the analyte level based on subsequent analyte data; and determining a subsequent medication dose based on the second analyte level relative to the analyte level threshold and the second rate of change relative to the rate of change threshold.Type: GrantFiled: January 21, 2019Date of Patent: August 29, 2023Assignee: Abbott Diabetes Care Inc.Inventors: Mark K. Sloan, Martin J. Fennell, Daniel M. Bernstein
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Patent number: 11730888Abstract: An auto-injector for administering a dose of a liquid medicament includes an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), operating the syringe to supply the dose of medicament (M), and retracting the syringe with the needle into the covered position. After delivering the medicament, an activator arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection.Type: GrantFiled: February 3, 2023Date of Patent: August 22, 2023Assignee: Sanofi-Aventis Deutschland GMBHInventors: Matthew Ekman, Timothy Donald Barrow-Williams, Yannick Hourmand
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Patent number: 11730891Abstract: A data collection device comprises: a first portion having one or more features configured for attaching of the first portion to a dosage knob of an injection device; a second portion rotatably coupled with the first portion, wherein at least part of the second portion is movable axially relative to the first portion; a sensor arrangement configured to detect rotation of the first portion relative to the second portion; and a processor arrangement configured to, based on said detected movement, determine a medicament amount expelled by the injection device, wherein the coupling arrangement is configured to provide a non-permanent coupling between the first portion and the dosage knob of the injection device.Type: GrantFiled: July 24, 2020Date of Patent: August 22, 2023Assignee: Sanofi-Aventis Deutschland GMBHInventors: Maurice Toporek, Matthias Felber, Christoph Matthias Gugl, Marcus-Meinolf Dittrich, Christian Nessel, Stephan Riedel, Armin Koller, Alexander Heinrich, Florian Eberli, Philipp Muller, Sven Zwicker
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Patent number: 11730868Abstract: A dialysis system including a disposable fluid pumping cassette including at least one flexible membrane attached to a housing and at least one port extending from the housing, the at least one port including a spike; at least one dialysis fluid supply in fluid communication with at least one tubing and tubing connector; an autoconnection device including a shuttle for moving the at least one tubing and tubing connector towards the spike of the at least one port, the autoconnection device including at least one lead screw in mechanical communication with the shuttle, a motor and power transmission equipment to transmit power from the motor to the at least one lead screw; and a controller programmed to operate the motor to move the at least one tubing and tubing connector towards the spike of the at least one port of the disposable fluid pumping cassette.Type: GrantFiled: April 30, 2019Date of Patent: August 22, 2023Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Robert W. Childers, Patrick Lee, Andrey Kopychev, Douglas Reitz, Rodolfo Roger, John E. Steck
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Patent number: 11730937Abstract: Separable microneedle arrays and microneedle patches are provided that may achieve sustained release of drug. The microneedle arrays may include one or more features that facilitate separation of the microneedles, such as a bubble structure. The microneedle arrays may include an effervescent material.Type: GrantFiled: October 11, 2018Date of Patent: August 22, 2023Assignee: Georgia Tech Research CorporationInventors: Mark R. Prausnitz, Richard N. Terry, Wei Li
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Patent number: 11717607Abstract: The disclosure relates to a drug delivery device having a drive unit includes a stator comprising a plurality of coils consecutively arranged in an axial direction, and an armature axially movable within the stator, the armature including a number of magnets and pole shoes consecutively arranged in the axial direction. A respective pole shoe is arranged between respectively neighbouring magnets. At least one axial end of the armature comprises a terminal pole shoe.Type: GrantFiled: May 12, 2020Date of Patent: August 8, 2023Assignee: Sanofi-Aventis Deutschland GMBHInventors: Christian Nessel, René Richter, Robert Witt, Richard Guenther
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Patent number: 11717610Abstract: An injection device for injecting medicament in a patient comprises a housing configured to house a fluid reservoir that has one of a plurality of volumes of medicament. An injection conduit fluidly coupled to the fluid reservoir defines a fluid pathway from the fluid reservoir to the patient. A firing mechanism is coupled to the fluid reservoir and is configured to expel the medicament from the fluid reservoir through the injection conduit. A volume setting mechanism is coupled to the firing mechanism and is configured to select the one of the plurality of volumes of medicament for the firing mechanism to expel. A dose setting mechanism is configured to select all or a fraction of the one of the plurality of volumes of medicament that is injected from the injection conduit when the firing mechanism is actuated.Type: GrantFiled: May 21, 2020Date of Patent: August 8, 2023Assignee: ANTARES PHARMA, INC.Inventors: Bryan James Sarkinen, Michael Travanty, Patrick Madsen, Andrew Charles Mork
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Patent number: 11717660Abstract: A microneedle structure has one or more microneedles (104) projecting from the major surface (102) of a substrate (100). The microneedle has a penetrating tip (106) formed at an intersection between upright surfaces (108) and an inclined surface (110) corresponding to a (1 1 1) crystallographic plane. The microneedle has an expanding portion bounded by a continuation of the upright surfaces (108) and inclined surface (110), and a constant cross-section portion bounded by a continuation of the upright surfaces and a slicing plane (112) extending from an edge (114) of inclined surface (110) towards, and perpendicular to, major surface (102) of the substrate. A width W of inclined surface (110) increases monotonically from penetrating tip (106) to edge (114).Type: GrantFiled: July 29, 2021Date of Patent: August 8, 2023Assignee: NANOPASS TECHNOLOGIES LTD.Inventors: Gal Admati, Yotam Levin, Yoav Hamisha
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Patent number: 11717659Abstract: A cell transplantation device for placing a cell group at a target region in at least one of an intradermal layer and a subcutaneous layer in a living body, including a device body including a protruding portion having an accommodating portion for accommodating a liquid composition including the cell group. The protruding portion has an opening that communicates with the accommodating portion, and the protruding portion penetrates a skin surface of the living body such that the opening of the protruding portion reaches the at least one of the intradermal layer and the subcutaneous layer and that the cell group accommodated in the accommodating portion is placed at the target region through the opening.Type: GrantFiled: March 27, 2020Date of Patent: August 8, 2023Assignee: TOPPAN PRINTING CO., LTD.Inventors: Yoshihiro Kodama, Hiromitsu Kinoshita
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Patent number: 11712403Abstract: An absorbent stoma pad for encapsulating an external bolster of a feeding tube is provided. The stoma pad includes an upper layer, base layer, absorbent material, and cavity. The upper layer, which includes an upper surface and a lower surface, contains a centrally located opening with respect to a periphery of the upper layer, wherein the opening is configured to receive a tube portion of the feeding tube. The base layer, which includes an upper surface and a lower surface, contains a centrally located opening with respect to a periphery of the base layer, wherein the opening is also configured to receive the tube portion of the feeding tube. Meanwhile, the absorbent material is disposed adjacent the upper layer's lower surface. Further, the cavity permits airflow between the absorbent layer and the base layer when the external bolster is encapsulated by the stoma pad and positioned within the cavity.Type: GrantFiled: March 2, 2017Date of Patent: August 1, 2023Assignee: O&M Halyard, Inc.Inventor: Donald McMichael
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Patent number: 11712525Abstract: An injection system includes a syringe body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the syringe body, forming respective proximal and distal drug chambers. The system further includes a plunger member configured to be manually manipulated to insert the proximal stopper member relative to the syringe body. Moreover, the system includes a fluid conveying assembly including a penetrating member configured to penetrate the distal stopper member to fluidly couple the proximal and distal drug chambers, a distal exit tube, and a transfer member disposed at least partially around a portion of the penetrating member and defining a fluid passage. A distal end of the penetrating member is disposed in the distal exit tube.Type: GrantFiled: June 22, 2020Date of Patent: August 1, 2023Assignee: Credence Medsystems, Inc.Inventors: Stephen H. Diaz, Gary Steese-Bradley, Alan E. Shluzas, Conor Edward Shanley, Mina M. Leung, Jeff Tillack
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Patent number: 11707616Abstract: Flow stop assemblies are described herein. A flow stop assembly configured to control flow through a tubing includes a flow stop base and a pincher. The flow stop base includes a base wall, at least one pincher guard, a tubing guide, a pincher recess, a pincher protrusion, and a base extension. The pincher is movable relative to the base extension and is configured to move between a flow position and an occlusion position, wherein in the flow position the pincher surface is spaced apart from the pincher protrusion and in the occlusion position, the pincher surface is disposed adjacent to the pincher protrusion and is configured to obstruct flow through the tubing.Type: GrantFiled: October 9, 2019Date of Patent: July 25, 2023Assignee: CAREFUSION 303, INC.Inventors: Jake Smith, Soon Park
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Patent number: 11701469Abstract: Devices and methods are disclosed that provide a syringe actuator device for use in the distention and irrigation of a body conduit before the use in a medical procedure such as a coronary bypass graft procedure. The device can be retrofit to a syringe by attaching it to the cap of the plunger and engaged to automatically apply pressure to fluid in the syringe. In some embodiments, elastic bands attached to the device are easily engaged or removed from a syringe during a procedure to limit the pressure on the syringe to various levels. The device may be overridden by an operator pushing on the plunger of the syringe as in normal syringe operation.Type: GrantFiled: April 27, 2020Date of Patent: July 18, 2023Inventor: Matthew John Petrides
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Patent number: 11701506Abstract: The present invention provides a solution to increase the drug loading capacity and drug delivery precision of dissolving microneedles. These solutions include: (a) increasing the base of the microneedle cavities without substantially changing the microneedle's height and geometry, (b) use of drug suspension and sedimentation of drug by centrifugation, and (c) a specific centrifugation order for filling drug and matrix material. In the first preferred embodiment, a microneedle master mould comprising a plurality of pyramidal microneedles (5100), wherein each of the pyramidal microneedles further comprising a chamfered base (5200) which extends to and adjoins with its neighbouring chamfered bases is provided.Type: GrantFiled: May 10, 2017Date of Patent: July 18, 2023Inventor: Chee Yen Lim
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Patent number: 11701460Abstract: A monitoring device may include a housing, which may include a distal end, a proximal end, and a fluid pathway extending through the proximal end and distal end. The distal end may include a connector configured to couple to a catheter assembly. The monitoring device may include one or more sensors disposed within the fluid pathway. The sensors may facilitate identification of an occlusion within the catheter assembly.Type: GrantFiled: April 6, 2020Date of Patent: July 18, 2023Assignee: Becton, Dickinson and CompanyInventors: S. Ray Isaacson, Vincent J. Sullivan, Brendan Tompkins, Charles D. Shermer
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Patent number: 11697009Abstract: Disclosed are a microneedle patch and a method for fabricating the microneedle patch. The microneedle patch includes a base layer including a mesh structure or auxetic materials having a negative Poisson's ratio, and a microneedle array disposed on the base layer. The method includes forming a base layer including a mesh structure or auxetic materials having a negative Poisson's ratio, and forming a microneedle array on the base layer.Type: GrantFiled: September 4, 2020Date of Patent: July 11, 2023Assignee: Industry-Academic Cooperation Foundation, Yonsei UniversityInventors: WonHyoung Ryu, SeungHyun Park, JiYong Lee, Jae Ho Kim