Patents Examined by Amelia Burgess
  • Patent number: 5062891
    Abstract: Metallization, applied by the thick film screening technique, utilized herein has glass-ceramic bonding agents designed to promote adhesion yet maintain the desired electrical properties and post-processing characteristics.
    Type: Grant
    Filed: August 13, 1987
    Date of Patent: November 5, 1991
    Assignee: Ceramics Process Systems Corporation
    Inventors: William C. Gruber, Eric A. Barringer
  • Patent number: 5059250
    Abstract: Red iron oxide pigments with improved coloring properties wherein the isoelectric point of the pigments is greater than 7.
    Type: Grant
    Filed: March 24, 1986
    Date of Patent: October 22, 1991
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wilfried Burow, Horst Brunn, Peter Kresse, Hans Sander
  • Patent number: 5057411
    Abstract: The polynucleotide sequence fragment conferring immunologic specificity to papillomavirus (PV) has been located and isolated. From this information, assays for type-specific PV, including DNA probes, RNA probes, immunoassays and the like are produced. The vaccines against specific PVs may be produced also.Further, the genus-specific amino acid sequence of the L1 capsid protein has been identified.
    Type: Grant
    Filed: May 1, 1989
    Date of Patent: October 15, 1991
    Assignee: Georgetown University
    Inventors: Wayne D. Lancaster, A. Bennett Jenson
  • Patent number: 5057152
    Abstract: This invention relates to surface cleaner/polish compositions comprising (i) a volatile liquid carrier selected from water, a monohydroxy alcohol having from 1 to 5 carbon atoms and mixtures thereof, and (ii) a crystalline aluminosilicate selected from Zeolite A, Zeolite X, Zeolite, Y, Zeolite P and mixtures thereof as an abrasive material, wherein said crystalline aluminosilicate has a particle size distribution sufficient to (a) provide enhanced wettability properties, (b) provide enhanced dispersion stability, (c) provide enhanced anti-fogging properties, (d) reduce or eliminate residual filming, and/or (e) reduce or eliminate dust during surface removal. This invention also relates to a process for preparation of the surface cleaner/polish compositions.
    Type: Grant
    Filed: June 24, 1987
    Date of Patent: October 15, 1991
    Assignee: UOP
    Inventors: Bonita K. Marcus, Anthony J. Gioffre, Marianne Elliott
  • Patent number: 5049662
    Abstract: A new NM23 gene and its relationship with metastatic potential of tumor cells is described.
    Type: Grant
    Filed: October 13, 1987
    Date of Patent: September 17, 1991
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Patricia S. Steeg, Lance A. Liotta, Mark E. Sobel, Generoso Bevilacqua
  • Patent number: 5049188
    Abstract: A recording liquid comprising from 0.2 to 12% by weight, based on the total weight of the recording liquid, of a water-soluble dyestuff, from 0.5 to 25% by weight, based on the total weight of the recording liquid, of at least one member selected from the group consisting of compounds of the following formulas I, II and III, and an aqueous medium: ##STR1## wherein l is a number of from 4 to 20, ##STR2## wherein R is a lower alkyl group or a phenyl group, and each of m and n is a number of from 4 to 20, and ##STR3## wherein X is a halogen atom, and p is a number of from 4 to 20.
    Type: Grant
    Filed: May 6, 1988
    Date of Patent: September 17, 1991
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Hiroshi Takimoto, Tomio Yoneyama, Hideo Sano
  • Patent number: 5043287
    Abstract: The instant invention is a process for the recovery from an aqueous solution of water soluble biopolymers, in particular polysaccharides, gums, agar, agarose and starches by the addition of polyoxide solution to the biopolymer containing solution. The biopolymer is then separated and collected.
    Type: Grant
    Filed: May 16, 1989
    Date of Patent: August 27, 1991
    Assignee: The Standard Oil Company
    Inventor: S. S. Johal
  • Patent number: 5041161
    Abstract: The present invention provides a novel ink jet ink which is semi-solid at room temperature. The subject ink combines the advantageous properties of thermal phase change inks and liquid inks. More particularly, the inks of the present invention comprise vehicles, such as glyceryl esters, polyoxyethylene esters, waxes, fatty acids, and mixtures thereof, which are semi-solid at temperatures between 20.degree. and 45.degree. C. *The ink is impulse jetted at an elevated temperature in the range of above 45.degree. C. to about 110.degree. C., at which temperature the ink has a viscosity of about 10-15 centipose. The subject inks exhibit controlled penetration and spreading, but do not remain on the surface of most substrates where they would be prone to burnishing, cracking or flaking. *These inks further comprise 0.1 to 30 wt. % of a colorant system.
    Type: Grant
    Filed: October 3, 1989
    Date of Patent: August 20, 1991
    Assignee: Dataproducts Corporation
    Inventors: Theodore M. Cooke, An-Chung R. Lin
  • Patent number: 5024701
    Abstract: Disclosed are improved denture adhesive compositions containing a hydrophobically modified water-soluble polymer alone or admixed with an alkali metal salt of carboxymethyl cellulose having a D.S. of at least 0.3. Hydrophobically modified hydroxyalkyl celluloses and copolymers of ethylene oxide and long chain epoxyalkanes are preferred as the water-soluble polymer.
    Type: Grant
    Filed: December 22, 1988
    Date of Patent: June 18, 1991
    Assignee: Hercules Incorporated
    Inventor: Armand J. Desmarais
  • Patent number: 5009708
    Abstract: A printing paste suitable for application by an elastically deformable stamp on a substrate and method for said application. The paste comprises a powdered solid component in an organic carrier with a weight ratio of between 6:4 and 8:2. The organic carrier comprises 4-9% by weight ethyl cellulose, 74-82% alpha-terpineol, and 8-17% benzyl alcohol. The paste may also contain up to 20% by weight of polyethylene glycol. The solid component of the paste is preferably a mixture of platinum and zirconium dioxide which can be applied as an electrically conductive paste to form a conductive coating on a substrate, preferably a tubular or other substrate having a non-planar surface. The paste has a viscosity of between 6 and 8.5 pascal seconds.
    Type: Grant
    Filed: August 31, 1989
    Date of Patent: April 23, 1991
    Assignee: Robert Bosch GmbH
    Inventors: Werner Grunwald, Gerhard Holfelder, Claudio De La Prieta, Kurt Schmid
  • Patent number: 5002867
    Abstract: A method is provided for sequencing nucleic acids without the need to separate similarly sized DNAs or RNAs by gel electrophoresis. The method relies on the separate hybridization of multiple mixed oligonucleotide probes to a target sequence. The mixed oligonucleotide probes comprise sequences of fixed and non-fixed bases corresponding to every possible permutation of fixed and non-fixed bases less than or equal to the length of the probes. For each probe, the hybridizations provide the number of times the probe's particular sequence of fixed bases appears in the target sequence. The target sequence is then mathematically reconstructed from this data and a knowledge of the probe sequences.
    Type: Grant
    Filed: October 24, 1988
    Date of Patent: March 26, 1991
    Inventor: Stephen C. Macevicz
  • Patent number: 5000092
    Abstract: Printing ink vehicles including an emulsion of a mineral oil, preferably a light mineral oil; a significant amount of water; and an emulsifying agent including an amine or alkali metal salt of an oxidized hydrocarbon wax. Printing inks incorporating the vehicles include the vehicle together with a coloring agent such as a pigment.
    Type: Grant
    Filed: February 26, 1988
    Date of Patent: March 19, 1991
    Assignee: Chemoxy International Limited
    Inventor: Robert D. M. Best
  • Patent number: 4999423
    Abstract: A novel acylated anthocyanin of the formula: ##STR1## (wherein R.sup.1 and R.sup.2 may be the same or different and each represents a hydrogen atom, a ferulyl group or a caffeyl group; R.sup.3 and R.sup.4 may be the same or different and each represents a ferulyl group or a caffeyl group; and ANION.sup.- represents an anion) and a process for producing the same, as well as a pigment composition containing said anthocyanin.
    Type: Grant
    Filed: March 11, 1988
    Date of Patent: March 12, 1991
    Assignee: Suntory Limited
    Inventor: Eiichi Idaka
  • Patent number: 4996143
    Abstract: Fluorescent stokes shift probes for polynucleotide hybridization assays are designed to provide predetermined nucleotide base unit spacings between the donor and acceptor fluorophores. When the probes are hybridized to the target polynucleotide the fluorophores paired for non-radiative energy transfer are separated by 2 to 7 nucleotide base units. The fluorophores are attached to the DNA or RNA probes by linker arms having lengths of 4 to 30 Angstroms. Fluorescein is a preferred donor for use with a Texas Red acceptor.
    Type: Grant
    Filed: April 13, 1990
    Date of Patent: February 26, 1991
    Assignee: Syngene, Inc.
    Inventors: Michael J. Heller, Edward J. Jablonski
  • Patent number: 4994372
    Abstract: This invention relates to processive DNA polymerases and methods for using them.
    Type: Grant
    Filed: December 6, 1988
    Date of Patent: February 19, 1991
    Assignee: President and Fellows of Harvard College
    Inventors: Stanley Tabor, Charles C. Richardson
  • Patent number: 4994565
    Abstract: From a cDNA library, a nucleotide sequence of a novel gene, called rig, specifically expressed by streptozotocin- or alloxan-nicotinamide-induced rat insulinomas was determined. Further, novel genes with base sequences homologous to rig were found in a BK virus-induced hamster insulinoma and in a surgically removed human insulinoma. The above DNA is transcribed to provide an mRNA. The above DNAs and mRNAs can be efficaciously employed for the medical purposes of pancreatic diseases.
    Type: Grant
    Filed: August 21, 1987
    Date of Patent: February 19, 1991
    Assignee: Tohoku University
    Inventor: Hiroshi Okamoto
  • Patent number: 4988617
    Abstract: Assay for determing the nucleic acid sequence in a region of a nucleic acid test substance having a known normal sequence and a known possible mutation at at least one target nucleotide position. Oligonucleotide probes are selected to anneal to immediately adjacent segments of a substantially complementary test DNA or RNA molecule. The target probe has an end region wherein one of the end region nucleotides is complementary to the normal or abnormal nucleotide at the corresponding target nucleotide position. A linking agent is added under conditions such that when the target nucleotide is correctly base paired, the probes are covalently joined and if not correctly base paired, the probes are incapable of being covalently joined under such conditions. The presence or absence of linking is detected as an indication of the sequence of the target nucleotide.
    Type: Grant
    Filed: March 25, 1988
    Date of Patent: January 29, 1991
    Assignee: California Institute of Technology
    Inventors: Ulf Landegren, Leroy Hood
  • Patent number: 4986850
    Abstract: A recording liquid including a mixture of a recording agent with a water-soluble organic solvent, and water, said mixture giving an aqueous solution having a viscosity of 25 cp or higher at a mixture-water ratio of 9:1 by weight, and giving an aqueous solution having a viscosity of 15 cp or lower at a ratio of 1:1 by weight at 25.degree. C., respectively. A recording method is also provided which includes attaching droplets of the above-mentioned recording liquid onto a recording medium.
    Type: Grant
    Filed: September 5, 1989
    Date of Patent: January 22, 1991
    Assignee: Canon Kabushiki Kaisha
    Inventors: Kazuo Iwata, Shinichi Tochihara, Shoji Koike
  • Patent number: 4983728
    Abstract: The present invention relates to probes of nucleic acids useful for detecting indifferently the various types of human papilloma virus, particularly HPV1a, HPV5, HPV6b, HPV8, HPV11, HPV16, HPV18 and HPV33, especially a probe comprising a labelled sequence of nucleic acids, characterized in that it comprises the oligomer of twelve nucleotides X-A-A-A-A-C-G-A-A-A-G-X, with X=T or U, or its complement by interchanging A and X on the one hand, C and G on the other hand. The present invention also relates to specific probes of nucleic acids for the detection of human papilloma for each of the types HPV1a, HPV5, HPV8, HPV11, HPV16, HPV18 and HPV33, as well as specific probes of sub-groups of the virus HPV16, HPV18, HPV33 or HPV16 and HPV18 only or again HPV5 and HPV8 only.
    Type: Grant
    Filed: July 28, 1988
    Date of Patent: January 8, 1991
    Assignee: Ire-Celltarg S.A.
    Inventors: Albert Herzog, Alfredo Cravador, Sophie Houard, Alex Bollen
  • Patent number: 4981783
    Abstract: A method is disclosed for the analysis of gene expression in human biopsy that is useful in the diagnosis and prognosis of disease and evaluation of risk for disease. The method comprises the steps of compiling data regarding the level of expression of certain individual cloned gene sequences from patients having defined pathological conditions and from normal patients and thereafter identifying sequences that characterize the pathological condition.The data regarding the expression of the individual cloned genes are stored in a defined pattern or array. Replicas of this array are hybridized to radioactive probes made using the RNA isolated from biopsy tissue. The extent of hybridization of the probe to each of the cloned sequences is proportional to the level of expression of the cloned sequence in the tissue from which the probe was made. This may be done by exposing the hybridized clones to x-ray film and scanning the x-ray films to quantify the cloned sequences.
    Type: Grant
    Filed: April 16, 1986
    Date of Patent: January 1, 1991
    Assignee: Montefiore Medical Center
    Inventor: Leonard Augenlicht