Abstract: A method and apparatus applies radiant energy through the skin to an underlying subcutaneous layer or deeper soft tissue layers that includes loculations of fat with fibrous septae made of collagen tissue. This creates a desired contour effect without substantially modifying melanocytes and other epithelial cells in the epidermis. A membrane conforms a contacting exterior surface of the membrane to a skin layer. One or more thermal electrodes positioned in the membrane. A focussing element focuses thermal energy to the underlying collagen tissue. The focusing element and the electrolytic solution create a reverse thermal gradient from the skin to the collagen tissue. A thermal power source is coupled to the thermal electrodes.

Abstract: The present invention is composed of required component capable of changing in color with which a daily product and so on are impregnated, painted or printed, such daily product is convenient in daily life by indicating a contact between the required component and urine and so on.

Abstract: A disinfectant composition contains ethyl alcohol with a concentration of not lower than 50% by weight, chlorhexidine, and an organic acid. Even when the concentration of ethyl alcohol is not lower than 50% by weight, chlorhexidine can be compounded therein very stably.

Abstract: A controlled release pharmaceutical composition in oral dosage unit form comprising a hard or a soft shell capsule containing a filling comprising a therapeutically effective number of active spherical granules comprising an effective amount of at least one carbonic anhydrase inhibitor active medicament, a pharmaceutically acceptable normally solid diluent adapted to form a diffusable matrix for the carbonic anhydrase inhibitor active medicament and an optional pharmaceutically acceptable excipient. A method for the preparation and for the administration of the above defined composition is provided as well.

Abstract: The invention presents an antithrombotic resin which is prepared by blending at least one type of antithrombotics, in polyurethane or polyurethane urea polymerized by using at least one type of polyether diol selected from the group consisting of polyol containing a polyoxyethylene group expressed in formula (I).paren open-st.CH.sub.2 CH.sub.2 O.paren close-st..sub.n (I)(where n is a number-average degree of polymerization of 1 to 100) and polyol containing a polyoxyethylene group expressed in formula (II).paren open-st.CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 O.paren close-st..sub.m(II)(where m is a number-average degree of polymerization of 1 to 100). This antithrombotic resin is capable of eluting the antithrombotic in the blood for a long time at high concentration. By using the antithrombotic resin of the invention, antithrombotic tube, antithrombotic film, antithrombotic coat, and others are obtained.

Abstract: A capsule shell comprising 79.6-98.7% by weight of a hydroxypropylmethyl cellulose, 0.03-0.5% by weight of carrageenan, and 0.14-3.19% by weight of a potassium ion and/or a calcium is prepared by drying an solution comprising 18-28% by weight of hydroxypropylmethyl cellulose whose 2% aqueous solution has a viscosity of 2.4-5.4 centistokes at 20.degree. C. as a base, 0.01-0.09% by weight of carrageenan as a gelling agent, and 0.05-0.6% by weight of a potassium ion and/or calcium ion as a co-gelling agent. The capsule shell exhibits disintegrating ability equivalent to gelatin shells without degrading that ability even under special conditions containing much calcium ions.

Abstract: The peat-derived bioactive product contains not more than 70%, preferably not more than 60% by weight of inorganic salts, especially of sodium chloride, based on dry solids. It is obtainable by a process wherein a highly concentrated aqueous solution of inorganic salts, especially of sodium chloride containing peat-derived bioactive ingredients is diluted with demineralized water and subjected to reverse osmosis in order to desalinate the solution, inorganic salts being removed, and wherein the resulting solution is concentrated and clarified, and, optionally, in at least one further step, sterilized and/or spray-dried.

Abstract: A process for the preparation of an oral solid rapidly disintegrating dosage form of a pharmaceutically active substance which has an unacceptable taste which process comprises forming a solution or a suspension in a solvent of a form of the pharmaceutically active substance which is less soluble in water and more palatable than the form with the unacceptable taste together with a water-soluble or water-dispersible carrier material, forming discrete units of the suspension or solution and removing the solvent from the discrete units under conditions whereby a network of the carrier material carrying a dosage of the less soluble and more palatable form of the pharmaceutically active substance is formed.

Abstract: A controlled release pharmaceutical tablet is disclosed which is based on:(a) a compressed core which contains:(i) a medicament;(ii) at least 23% to 55% by weight, based on the total weight of the core, of a water soluble osmotic agent;(iii) a water soluble pharmaceutically acceptable polymeric binder;(iv) a water-swellable pharmaceutically acceptable polymer;(v) a conventional pharmaceutical excipient; and(b) a membrane coating around said core tablet which consists essentially of:(i) a modified water insoluble pharmaceutically acceptable polymer; and(ii) a pharmaceutically acceptable water soluble polymer.

Abstract: The present invention is a method and a dosage unit for delivery of a controlled-release system. The dosage unit is a quick dissolve unit which can be prepared by mixing uncured shearform matrix and a controlled-release system, either molding or compacting a unit dosage form and curing the shearform matrix. The controlled-release systems used in the present invention include instantaneous release components, delayed release components, sustained release components, and combinations thereof.

Abstract: A hair treating method for imparting curl retention to hair in which at least one film forming ingredient is applied to the hair. The improvement utilizes as the film forming ingredient an organosilicon compound which is a nonpolar silsesquioxane. Hair fixative compositions including the nonpolar silsesquioxane are also disclosed.

Abstract: The present invention is a process for forming a low density compression dosage unit to provide increased strength. The process of the present invention includes compacting under bi-level compaction pressure to provide a continuous-volume dosage unit which has a first volume defining an edge portion of the unit and a density which is greater than a density of a second volume defining a non-edge portion of the unit. The present invention also includes the product resulting from the process and apparatus used to make such units.

Abstract: A highly effective, ammonia-free, permanent waving lotion is attained by employing one a reducing agent consisting of a thiol compound or mercaptan in combination with an alkalizing agent consisting of an alkanolamine and an alkali metal hydroxide. In accordance with this invention, the reducing agent is employed either independently as an aqueous solution or in association with desired additives for imparting additional benefits to the permanently waved hair. Preferably, the reducing agents of the present invention are employed in a permanent waving lotion having a pH ranging between about 5.5 and 10.0. By employing this invention, long lasting permanently waved hair is attained with substantially less malodor being produced, thereby providing increased comfort to the stylist and the person who undergoes permanent waving.

Abstract: Long acting narcotic compositions comprising a water-soluble analgesic or antagonist drug dispersed within a polymer matrix, methods of producing the same and treatments with the complex.

Abstract: The present invention relates to a stable, aqueous odor-absorbing composition, for use on inanimate surfaces. The composition comprises from about 0.1% to about 5%, by weight of the composition, of solubilized, water-soluble, uncomplexed cyclodextrin, an effective amount of a solubilized, water-soluble, antimicrobial preservative having a water-solubility of greater than about 0.3%, optional perfume, and an aqueous carrier.The composition is essentially free of any material that would soil or stain fabric and has a pH of greater than about 3. The composition can be incorporated into a spray dispenser to create an article of commerce that can facilitate treatment of articles and/or surfaces with uncomplexed cyclodextrin solutions of a level that is effective yet is not discernible when dried on the surface.

Abstract: Long acting narcotic compositions comprising a water-soluble analgesic or antagonist drug dispersed within a polymer matrix, methods of producing the same and treatments with the complex.

Abstract: A skin care composition in the form of a low pH aqueous gel. The compositions provide improved skinfeel and residue characteristics together with excellent moisturizing, emolliency, rub-in and absorption characteristics.

Abstract: An apparatus and process for administering minerals to the human body by mixing pre-selected particulated minerals with graphite and coal tar to form a bar (10a), vaporizing the bar (10a) to form a mineral rich vapor, and directing the vapor to a patient's skin using an enclosure (30).

Abstract: A small, reusable, previously cooled or frozen bladder that is applied to the anal area of a user. The bladder consists of two two-ply sheets of a flexible, semi-porous material, such as polyethylene, hermetically heat sealed together at the edges to form an internal cavity. The cavity contains a cold-temperature storage means, such as water, glycerol, a combination thereof, or other chemical slurry, and a medicinal agent, such as witchhazel, shark oil, yarrow, other astringents, and lidocaine or other pain relievers.

Abstract: Lipcolor comprising a salt or hydroxide of di-or trivalent metal, a water-soluble alginate, a red or orange lake color having a COONa or COOK group, and an oil coponent having appearance of liquid at 20.degree. C. The lipcolor less yields a dry feeling or an uneasy feeling with the passage of time, and its color comes off less in friction with foods and drinks.