Abstract: The ceramide composition includes capsules dispersed in the ceramide composition, the capsules comprising a shell and a core. The shell includes a polycaprolactone, a block copolymer, and a surfactant. The core includes ceramide NP, hydroxypalmitoyl sphinganine, 2-oleamido-1,3-octadecanediol, and a hydrophobic solvent. The core has a weight ratio of the ceramide NP of (i) and the hydroxypalmitoyl sphinganine of (ii) to the 2-oleamido-1,3-octadecanediol of (iii) is from 1:2.5 to 1:5. Additionally, the ceramide composition includes hydroxyacetophenone and hydrophilic solvent.
Type:
Grant
Filed:
March 31, 2020
Date of Patent:
May 18, 2021
Assignee:
L'OREAL
Inventors:
Laurianne Le Claire, Miao Wang, Jerome Cottard
Abstract: Compositions suitable for use as cosmetic products (e.g., skin cream) are disclosed. Methods of making and using compositions suitable for use as cosmetic products are also disclosed.
Abstract: The present invention relates to a cosmetic or dermatological composition comprising, in a physiologically acceptable support: a) at least one merocyanine compound of formula (1) or (2) and b) at least one oily phase and c) at least one C1-C4 monoalkanol. The present invention also relates to a non-therapeutic cosmetic process for caring for and/or making up a keratin material, comprising the application, to the surface of the said keratin material, of at least one composition as defined above. The invention also relates to a non-therapeutic cosmetic process for limiting the darkening of the skin and/or improving the colour and/or uniformity of the complexion, comprising the application, to the surface of the skin, of at least one composition as defined previously.
Type:
Grant
Filed:
January 20, 2014
Date of Patent:
May 11, 2021
Assignee:
L'OREAL
Inventors:
Angelina Roudot, Alexandra Suida-Batista, Didier Candau, Florence Levy
Abstract: A biopatch, a bioheater, a biosensor and a bioelectronic patch device are provided. The biopatch comprises a polymer film comprising a biopolymer and a drug loaded in the polymer film. The biopolymer may comprise one or more than one of a bioabsorbable polymer, a biodegradable polymer and a biocompatible polymer. The biopolymer may comprise oxidized starch. The drug may comprise a first drug chemically combined with the oxidized starch and a second drug physically combined with the oxidized starch. The bioheater comprises a heater comprising biometal. The biometal may comprise Mg or Fe. The heater can be controlled wirelessly by an alternating magnetic field.
Type:
Grant
Filed:
December 7, 2016
Date of Patent:
May 4, 2021
Inventors:
Daehyeong Kim, Seunghong Choi, Taeghwan Hyeon, Jongha Lee, Hyerim Cho, Hyunseon Seo
Abstract: The disclosure relates to systems and compositions comprising the systems for use in chemical treatment of keratinous substrates, such as the hair. The systems and compositions comprising the systems comprise at least one active agent and at least one acid. Methods of treating keratinous substrates with the systems and compositions comprising the systems are also disclosed.
Type:
Grant
Filed:
February 12, 2019
Date of Patent:
May 4, 2021
Assignee:
L'OREAL
Inventors:
Kimberly Dreher, Gérard Provot, Dariusz Danielski, Fabien Boulineau, Caroline Rahmouna Francoise Goget, Anthony Potin, Allison Chin, Michael Degeorge, Mara Applebaum, Mary Abraam Soliman, Ashley Ann Figatner, Megan Pauker, Emmanuel Appiah-Amponsah
Abstract: The invention refers to a pharmaceutical or nutraceutical composition comprising a core a) comprising an active ingredient and a water-insoluble polymer, a coating layer b) above the core a) comprising a salt of an alginic acid, and a coating layer c) above the coating layer b) comprising an anionic (meth)acrylate copolymer polymerized from a (meth)acrylate monomer mixture comprising 5-75% by weight in relation to the total weight of the (meth)acrylate monomer mixture of (meth)acrylate monomers with an anionic group, wherein the amount of the water-insoluble polymer in the core a) is 2 to 20% by weight in relation to the weight of the core a) and the amount of the salt of an alginic acid in the coating layer b) is 5 to 85% by weight in relation to the weight of the core a) and the amount of the anionic (meth)acrylate copolymer in the coating layer c) is 10 to 75% by weight in relation to the weight of the core a) and to the coating layer b).
Abstract: The invention relates to a composition, especially a cosmetic composition, comprising at least one acrylic thickener and at least one oil, as well as to methods of using such compositions.
Type:
Grant
Filed:
October 16, 2018
Date of Patent:
April 20, 2021
Assignee:
L'OREAL
Inventors:
Chunhua Li, Hy Si Bui, Dhaval Patel, Mohamed Kanji, Geoffrey White
Abstract: Curable antifouling compositions include fluorinated polymers that contain a perfluoropolyether group, a poly(alkyleneoxide) group, a hydrolyzable silane group and a cationic curative. The curable antifouling compositions can be applied on a surface of a substrate, and at least partially cured to provide an article with antifouling properties.
Type:
Grant
Filed:
November 8, 2013
Date of Patent:
March 16, 2021
Assignee:
3M Innovative Properties Company
Inventors:
Zai-Ming Qiu, Alexander J. Kugel, Michael J. Svarovsky
Abstract: The present invention relates to a composition for the synthesis of ATP as an energy supplementation. The composition comprises a plant extract or a plant fraction suitable to produce ATP upon exposure to light. The present invention also relates to the isolation of such plant extract and to its use in energy drinks.
Abstract: The present invention provides a new process for stabilizing the particle size of micronized glycopyrronium salt (such as glycopyrronium bromide) which yields a micronized product exhibiting improved chemical and polymorphic stability even after prolonged storage. The invention also relates to compositions comprising said stabilized glycopyrronium salt (such as glycopyrronium bromide) and to dry powder inhaler devices and capsules or blisters comprising the stabilized glycopyrronium salt (such as glycopyrronium bromide). The glycopyrronium salt (such as glycopyrronium bromide) or compositions of the invention may be used as a medicament, for instance in the treatment of asthma, chronic obstructive pulmonary disease or cystic fibrosis or related diseases.
Type:
Grant
Filed:
July 25, 2017
Date of Patent:
January 12, 2021
Assignee:
INKE, S.A.
Inventors:
Josep Terradas Camins, Josep Maria Carulla Oliver, Silvia Donnici Garcia, David Gomez Lamarca, Maria Jose Martinez Velon, Emma Recio Soler
Abstract: Disclosed herein is a micro particle with a diameter of 10-100 microns, wherein the micro particle is coated with silver nanoparticles; and wherein the nanoparticles are coated with a polysaccharide; and wherein the polysaccharide coating is digestible by bacteria. Also, disclosed is a method of making silver nanoparticles using an ascorbic acid derivative or an alpha-hydroxyl carboxylic acid derivative as a reducing agent. The silver nanoparticles may be coated onto micro particles, embedded in hydrogel particles or coated with polysaccharide. The silver nanoparticles may be used in a wound dressing, a bandage, a fungal treatment product, a deodorant, a floss product, a toothpick, a dietary supplement, dental X-ray, a mouthwash, a toothpaste, acne or wound treatment product, skin scrub, and skin defoliate agent.
Abstract: Aqueous surfactant compositions containing in each case one or more alpha-sulfo fatty acid disalt, a sulfoketone, a specific cationic polymer, a soap, an inorganic salt of sulfuric acid, and water are disclosed. The compositions have good foaming ability, a pleasant sensory feel to the foam, good skin compatibility, and are suitable for cosmetic products, detergents, and cleaning products.
Abstract: A method of preventing or treating cutaneous pigmentation disease in a subject in need thereof, includes: providing a pharmaceutical composition comprising SDF1, an inducer or activator of SDF1, as an active ingredient; and administering the pharmaceutical composition to the subject, wherein the cutaneous pigmentation is prevented or treated, and the cutaneous pigmentation disease is selected from the group consisting of melasma, freckles, lentigo, nevus, pigmentation by drugs, pigmentation after inflammation and hyperpigmentation incurred from dermatitis.
Type:
Grant
Filed:
October 30, 2018
Date of Patent:
December 8, 2020
Assignee:
AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventors:
Hee Young Kang, Tae Jun Park, Jung Eun Yoon, Mi Sun Kim
Abstract: Disclosed herein are novel amine-functionalized porphyrin compounds, as wells as pharmaceutically acceptable salts or esters thereof. The disclosed compounds can be used to impart antioxidant, anti-inflammatory, anti-microbial, and/or cell-adhesion specificity to a surface or material in need thereof, such as a surface of an indwelling medical implant, or a marine surface.
Type:
Grant
Filed:
July 16, 2019
Date of Patent:
December 8, 2020
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education
Inventors:
Xinyan Cui, Noah Snyder, Kasey Catt, James Eles
Abstract: The invention relates to the technical field of the herbicides and/or plant growth regulators. Specifically, the invention primarily relates to novel substituted isothiazolopyridones, and compositions comprising said novel substituted isothiazolopyridones. Further, the present invention relates to processes for the preparation said novel substituted isothiazolopyridones and their use as herbicides and/or plant growth regulators.
Type:
Grant
Filed:
June 28, 2018
Date of Patent:
November 24, 2020
Assignee:
BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventors:
Jullien Rey, Joerg Tiebes, Marc Mosrin, Thomas Droege, Hansjoerg Dietrich, Anu Bheemaiah Machettira, Elmar Gatzweiler, Christopher Hugh Rosinger, Dirk Schmutzler, Daniela Portz, Kerstin Ilg, Philippe Rinolfi
Abstract: A biofilm sealant is provided imparting a residual biocidal property. The biofilm sealant is used to treat a surface to impart a film having a capacity to quickly kill bacteria and other germs for at least 24 hours after deposit of the film on a treated surface. The disinfectant formulation biofilm sealant comprises a polymer binder, wherein the polymer binder is an oxazoline homopolymer or an extended or a modified polymer based on an oxazoline homopolymer, and a biocidal compound.
Type:
Grant
Filed:
May 23, 2016
Date of Patent:
November 24, 2020
Assignees:
Microban Products Company, W.M. Barr & Company, Inc.
Inventors:
Tian Lan, Samuel James Hanna, Gina Parise Sloan, Brian Patrick Aylward, Karen Terry Welch, Dennis Earl Shireman, Kevin Andrew Kavchok, Charles L. Hawes
Abstract: A disinfectant formulation is provided imparting a residual biocidal property. The disinfectant formulation is used to treat a surface to impart a film having a capacity to quickly kill bacteria and other germs for at least 24 hours after deposit of the film on a treated surface. The disinfectant formulation comprises a polymer binder, wherein the polymer binder is an oxazoline homopolymer or an extended or a modified polymer based on an oxazoline homopolymer, and a biocidal compound. The disinfectant formulation further comprises a carrier. An article having the disinfectant formulation is provided as well as methods of making, using and applying the disinfectant formulation.
Type:
Grant
Filed:
November 23, 2015
Date of Patent:
November 17, 2020
Assignees:
Microban Products Company, W.M. Barr & Company, Inc.
Inventors:
Tian Lan, Samuel James Hanna, Gina Parise Sloan, Brian Patrick Aylward, Karen Terry Welch, Dennis Earl Shireman, Kevin Andrew Kavchok, Charles L. Hawes
Abstract: The present invention discloses a method to continuously manufacture micro- and/or nanoparticles of single component particles or multi-component particles such as particulate amorphous solid dispersions or particulate co-crystals. The continuous method comprises the steps of 1. preparing a first solution comprising at least one component and at least one solvent and a second solution comprising at least one anti-solvent of the at least one component comprised in the first solution, 2. mixing said first solution and said second solution by means of microfluidization to produce a suspension by precipitation or co-precipitation, 3. feeding said suspension to a filtration system to obtain a concentrate stream, 4. feeding said concentrate stream to a spray dryer, 5. atomizing said concentrate stream using at least one atomization nozzle, 6. drying said atomized concentrate stream to obtain particles, and 7. collecting said particles.
Type:
Grant
Filed:
March 30, 2016
Date of Patent:
November 3, 2020
Assignee:
Hovione Scientia Limited
Inventors:
Tiago Fonseca, Iris Duarte, Márcio Temtem, João Vicente
Abstract: The invention relates to liquid compositions for use with hair removal devices comprising a methathesized unsaturated polyol ester for improved lubrication.
Type:
Grant
Filed:
July 7, 2017
Date of Patent:
November 3, 2020
Assignee:
The Gillette Company LLC
Inventors:
Luke Andrew Zannoni, Beth Ann Schubert, Rajan Keshav Panandiker, Joseph Jay Kemper, Robert John Strife, Safa Motlagh, Jeffrey John Scheibel, Alison Fiona Stephens, Philip Andrew Sawin
Abstract: Fatty acid-based, pre-cure-derived biomaterials, methods of making the biomaterials, and methods of using them as drug delivery carriers are described. The fatty acid-derived biomaterials can be utilized alone or in combination with a medical device for the release and local delivery of one or more therapeutic agents. Methods of forming and tailoring the properties of said biomaterials and methods of using said biomaterials for treating injury in a mammal are also provided.
Type:
Grant
Filed:
October 26, 2017
Date of Patent:
October 27, 2020
Assignee:
ATRIUM MEDICAL CORPORATION
Inventors:
Keith M. Faucher, Hui Tang, Paul Martakos, Theodore Karwoski, Alison Sullivan, Greg Melville, Scott E. Corbeil