Abstract: Techniques are described herein for delivering a particle beam from a continuously rotating gantry towards a target according to a determined patient state. The determined patient state and an identified gantry angle of a gantry may be used to deliver a set of beamlets (e.g., a pattern of radiation dose) to the target. The particle beam may rotate through a range of gantry angles. The set of beamlets may be delivered continuously while the gantry rotates.

Abstract: A method for measuring electron mobility according to the present invention, which is performed by an apparatus comprising a chamber forming a sealed space, an electron gun provided in the chamber, and a metal sample disposed opposite to the electron gun in the sealed space, comprises: an electron irradiation step of irradiating the metal sample with electrons by the electron gun; a sample current measurement step of applying a voltage to the metal sample to measure a sample current obtained in the metal sample according to the applied voltage; a secondary electron current calculation step of calculating a secondary electron current through the measured sample current; and an effective incident current definition step of defining the sum of the measured sample current and the calculated secondary electron current as an effective incident current.

Abstract: A positioning system for an electron microscope includes a first carriage comprising a holder for holding a workpiece and a second carriage. The first carriage being coupled to one or more first drive units configured to position the workpiece along first, second, and third axes, and along a first tilt axis. The second carriage housing the one or more first drive units and being coupled to one or more second drive units configured to position the workpiece along a second tilt axis.

Abstract: A mass spectrometer or ion mobility spectrometer is disclosed comprising: a first device for separating ions or molecules according to a physicochemical property (3); an ion mobility separation device (4) for receiving and separating at least some of said ions or ions derived from said molecules according to their ion mobility; a gas supply (6-10) connected to said ion mobility separation device (4) for supplying gas into said ion mobility separation device (4); and a control system (11) configured to adjust said gas supply (6-10) so as to change the composition of gas within the ion mobility separation device (4) as a function of time.

Abstract: A method for determining a configuration setting of a source of ionizing radiation reducing a radiation dose absorbed by a patient and a practitioner in a medical operating room during a procedure. Prior to the procedure a database of maps of simulated propagation and scattering of ionizing radiation in a model of the medical operating room is obtained for different configuration settings. During the procedure, a position of the practitioner is determined. After determining a set of configuration settings of the source enabling the production of an image of a target anatomical structure a radiation dose absorbed by the patient and the practitioner is determined using the maps from the database. A recommended configuration setting for which a combined radiation dose is reduced is then outputted.

Abstract: Systems and methods are disclosed for analyzing a sample using overlapping precursor isolation windows. A mass analyzer of a tandem mass spectrometer is instructed to select and fragment at least two overlapping precursor isolation windows across a precursor ion mass range of a sample using a processor. The tandem mass spectrometer includes a mass analyzer that allows overlapping precursor isolation windows across the mass range of the sample.

Abstract: Disclosed herein is a forced irradiated air shielding mechanism that is an effective protective measure against Covid-19. The UV-C irradiated forced air flow face shield described herein is compact enough to be camouflaged under a cap. In this work it is mathematically proven that the described UV-C irradiated forced air flow face shield by itself provides more effective protection against the Covid-19 or similar airborne pathogens. The shield can be enabled using a mercury discharge tube or light emitting diode (LED) irradiator. Computational fluid dynamics is presented to show that positive irradiated air pressure ensures that the only air breathed by the wearer is irradiated. Also presented is a face shield testing apparatus.

Abstract: An example particle therapy system includes a particle accelerator to output a particle beam having a spot size; a scanning system for the particle accelerator to scan the particle beam in two dimensions across at least part of a treatment area of an irradiation target; and an adaptive aperture between the scanning system and the irradiation target. The adaptive aperture includes structures that are movable relative to the irradiation target to approximate a shape to trim part of the treatment area. The part of the treatment area has a size that is based on an area of the spot size.

Abstract: Techniques are described herein for delivering a particle beam from a continuously rotating gantry towards a target according to a determined patient state. The determined patient state and an identified gantry angle of a gantry may be used to deliver a set of beamlets (e.g., a pattern of radiation dose) to the target. The particle beam may rotate through a range of gantry angles. The set of beamlets may be delivered continuously while the gantry rotates.

Abstract: Methods and apparatuses for ion manipulations, including ion trapping, transfer, and mobility separations, using traveling waves (TW) formed by continuous alternating current (AC) are disclosed. An apparatus for ion manipulation includes a surface to which are coupled a first plurality of continuous electrodes and a second plurality of segmented electrodes. The second plurality of segmented electrodes is arranged in longitudinal sets between or adjacent to the first plurality of electrodes. An RF voltage applied to adjacent electrodes of the first plurality of electrodes is phase shifted by approximately 180° to confine ions within the apparatus. An AC voltage waveform applied to adjacent electrodes within a longitudinal set of the second plurality of segmented electrodes is phase shifted on the adjacent electrodes by 1°-359° to move ions longitudinally through the apparatus for separation.

Abstract: The invention relates to a sanitary interface device that provides safety and mitigates risk associated with the spread of disease and illness (e.g., viruses) resulting from human contact with potentially contaminated objects such as a handle. The interface device includes a rigid, U-shaped body having a curved portion and a pair of legs projecting therefrom. The curved portion interfaces with the potentially contaminated handle, while the pair of legs shield a user's hands from the handle. The interface device can be portable and reusable, while being adapted for use as part of a kit which could also include accessories, such as a case, stand and/or satchel.

Abstract: A method and apparatus for monitoring and/or controlling the extent of denaturation and/or bond cleavages of proteins on any surface (e.g., biological tissues, biofilms, etc.). In one embodiment, a low power laser (e.g., a 5 mW, 362 nm diode laser) is directed through a biological sample to a photodetector. The sample is heated by a set of radiant heaters to between about 220° C. and about 250° C. in a time period of between 10 seconds to 60 seconds. The baseline transmissivity of the sample is monitored continuously throughout treatment of the biological sample via continuous monitoring of the signal voltage detected at the photodetector. Upon detection of increase in relative transmissivity in the biological sample, the heating treatment is concluded and the biological sample is removed for in situ protein identification as part of an imaging MALDI-MS measurement.

Abstract: A germicidal panel light includes a housing, a sterilization component, a fan component and a lighting component; the housing provided with a mounting cavity as well as an air inlet and an air outlet connecting to the mounting cavity, inner wall of the mounting cavity forming an air guiding plane corresponding to the air inlet and the air outlet respectively, the appearance of the housing provided with a containing groove whose inner wall is provided as a reflecting surface; the sterilization component is provided in the mounting cavity; the fan component is provided in the mounting cavity and is provided at intervals with the sterilization component; and the lighting component is provided in the containing groove. The germicidal panel light has an air guiding plane in the mounting cavity nearby the air inlet, so air can be guided into the mounting cavity, air flows slowly, and noises are reduced.

Abstract: A load and sterilization combination control circuit arranged on a suction device includes a main control unit, a battery management unit, a load output unit, a load detection circuit and an ultraviolet sterilization circuit including an operation switch and an enabled switch connected with the operation switch in series and the main control unit. The load detection unit and the enabled switch are conducted to externally output. When a load of the suction device applied on the load output unit is detected by the main control unit via the load, detection circuit, the operation switch is configured to perform on-off control on the entire ultraviolet sterilization circuit after the enabled switch is turned on. The present disclosure can avoid waste electricity due to misoperation by performing a linkage control thereof and the ultraviolet sterilization circuit can work normally only after by connecting with the load and closing the operation switch.

Abstract: A system and method for an antivirus and radiation detection system configured to protect a wearer is provided. The system includes a personal protective equipment for preventing respiratory infection that includes a body configured to cover a nose and mouth of the user the body including at least one filter element disposed in the body that allows air to pass through the filter element from a first side of the body to a second side of the body; the filter element having a filter media; an ultraviolet light element disposed in the filter element that provides ultraviolet light into the filter media; and a pulsing laser element disposed in the filter element.

Abstract: Provided are a light blocking apparatus and an air purifier including the light blocking apparatus. The light blocking apparatus includes a housing, a light blocking member and a through hole. The through hole is located in the housing. A spacing or a gap is provided between the light blocking member and the housing. Projection of the light blocking member in spaced relationship from the housing covers the through hole.

Abstract: An automatic disinfection workstation system utilizes a disinfecting workstation-light to disinfect surfaces within the workstation and may also include an airflow disinfecting system that utilizes an airflow disinfecting light to disinfect an airflow through the workstation. The workstation may have three walls forming the workstation enclosure and the disinfecting workstation-light may be configured proximal to the top of the walls and emit ultraviolet light to deactivate or kill germs or viruses within the line of sight of the light. The disinfecting workstation-light is actuated over the workstation to produce light with various lines of sight to more effectively disinfect the workstation. In addition, a light-angle actuator may rotate the light to further increase the various lines-of-sight. This combination of traversing the light at various angles may further enhance the effectiveness of disinfecting the workstation.

Abstract: An object of the invention is to provide a technique of capturing images at higher speed and higher magnification when acquiring continuous tilted images with an electron microscope. The electron microscope of the invention includes a first spherical receiver fixed to a column of the electron microscope and configured to slide with a spherical fulcrum provided at a tip end of a sample holder; a spherical surface part provided on the column; and a second spherical receiver provided outside the column. The spherical surface part and the second spherical receiver slide on a contact part between the spherical surface part and the second spherical receiver, and a track of the slide is along a spherical surface centered on a central axis of the first spherical receiver, so that a view shift and a focus shift from an observation position of a sample can be reduced.

Abstract: An ultraviolet-C light fixture is provided, the ultraviolet-C light fixture comprising at least one ultraviolet-C light bulb to sterilize an air flow, an ultraviolet-C radiation field created by the at least one ultraviolet-C light bulb to sterilize the air flow, a top end cap, a base and a plurality of louvers, the plurality of louvers positioned proximate one another, the top end cap and the base to create a gap, the gap sized to allow ultraviolet radiation to pass outside the ultraviolet light fixture to create a sterilization field outside the ultraviolet light fixture to eradicate bacterial, viral or pathogen particles from the air flow surrounding the fixture and the gap sized to allow passage of the air flow containing a cloud of infectious bacterial, viral or pathogen particles to pass through a sterilization chamber within the ultraviolet light fixture to eradicate bacterial, viral or pathogen particles from the air flow.

Abstract: A multi-reflecting time-of-flight mass spectrometer (MR-TOF MS) includes an ion source, an orthogonal accelerator, and an ion mirror assembly. The ion source is capable of generating a beam of ions, and is arranged to accelerate the ions in a first direction along a first axis. The orthogonal accelerator is arranged to accelerate the ions in a second direction along a second axis. The second direction is orthogonal to the first direction. The ion mirror assembly includes a plurality of gridless planar mirrors and a plurality of electrodes. The plurality of electrodes are arranged to provide time-focusing of ions along a third axis substantially independent of ion energy and ion position.