Abstract: A wrist-worn pressure sensing device includes a pressure sensor. The wrist-worn pressure sensing device also includes a first strap that sets the position of the pressure sensor on a wearer's wrist and a second strap that engages with the first strap to adjust the overall length of the strap without moving the set position of the pressure sensor on the wearer's wrist.

Abstract: A system for heart performance characterization and abnormality detection includes an interface for receiving digitized electrical signals representing blood pressure waveforms over one or more heart beat cycles. The digitized electrical signals comprise, a first digital data sequence representing normal blood pressure of a patient, a second digital data sequence representing random blood pressure of a normal patient and a third digital data sequence representing a potentially abnormal blood pressure of a patient. A complexity processor calculates first, second and third complexity indices for the corresponding first, second and third digital data sequences respectively. A correlation processor uses the calculated first, second and third complexity indices to calculate one or more measures indicating deviation of the potentially abnormal blood pressure of the patient from a normal value.

Abstract: A CPU detects pulse waves in a pressure signal of a cuff detected during a period of reducing pressure applied by the cuff to a measurement site and acquires blood flow sound signals corresponding to blood flow sounds occurring in the pressure reduction period. Then, data for a pulse wave envelope that associates the amplitude values of the detected pulse waves with the pressurizing pressures at the pulse wave generation times, and data for a blood flow sound envelope that associates the amplitude values of the blood flow sound signals with the pressurizing pressures at the blood flow sound generation times are generated, and the data for the pulse wave envelope and the data for the blood flow sound envelope are used to determine whether or not there is periodic variation in the blood pressure during the pressure reduction period.

Abstract: According to one embodiment, a sleep sensor which is attached to a user who is sleeping when it is to be used is provided. The sleep sensor includes a first detector, an estimation module, a second detector and a control module. The first detector is configured to detect an acceleration signal representing acceleration that is obtained from the sleep sensor. The estimation module is configured to estimate the user's body position based on the detected acceleration signal. The second detector is configured to detect a signal for estimating a state other than the user's body position. The control module is configured to operate the second detector when the estimated user's body position is at least one of predefined body positions.

Abstract: Provided herein are implantable systems that include an implantable photoplethysmography (PPG) sensor, which can be used to obtain an arterial PPG waveform. In an embodiment, a metric of a terminal portion of an arterial PPG waveform is determined, and a metric of an initial portion of the arterial PPG waveform is determined, and a surrogate of mean arterial pressure is determined based on the metric of the terminal portion and the metric of the initial portion. In another embodiment, a surrogate of diastolic pressure is determined based on a metric of a terminal portion of an arterial PPG waveform. In a further embodiment, a surrogate of cardiac afterload is determined based on a metric of a terminal portion of an arterial PPG waveform.

Abstract: Devices, system, and methods generate expiratory flow-based pulmonary function data by processing a digital audio file of sound of a subject's forced expiratory maneuver. A mobile device configured to generate expiratory flow-based pulmonary function data includes a microphone, a processor, and a data storage device. The microphone is operable to convert sound of the subject's forced expiratory maneuver into a digital data file. The processor is operatively coupled with the microphone. The data storage device is operatively coupled with the processor and stores instructions that, when executed by the processor, cause the processor to process the digital data file to generate expiratory flow-based pulmonary function data for assessing pulmonary function of the subject. The sound of the subject's forced expiratory maneuver can be converted into the digital data file without contact between the subject's mouth and the mobile device.

Abstract: The blood pressure measurement apparatus includes a pressure sensor that detects the pressure in a cuff and outputs a cuff pressure signal, and a pulse wave detection unit that detects a pulse wave in the cuff pressure signal. The pulse wave detection unit includes an analog HPF that extracts a high-frequency component from the cuff pressure signal, an A/D conversion unit, a signal storage unit that stores a signal obtained by performing A/D conversion on the cuff pressure signal detected at the time when the pressurizing pressure changes from increasing to decreasing, a subtraction unit that subtracts the signal stored by the signal storage unit from an output signal of the A/D conversion unit, and a digital HPF that extracts a high-frequency component from the output signal of the subtraction unit.

Abstract: A handle component of the present invention into which atmospheric air is inhaled and breath is exhaled in the analysis of breath comprises inhalation holes, an inhalation inlet, an inhalation path, a breath discharge component, and an exhalation path. The inhalation holes are disposed near the tube connected for conducting exhaled breath to an analysis device main body for analyzing this breath, and are holes through which atmospheric air is inhaled into the interior of the handle component. The inhalation inlet is a place where the atmospheric air inhaled from the inhalation holes is sent into the body. The inhalation path is disposed between the inhalation inlet and the inhalation holes. The breath discharge component is a place where breath discharged from the body is taken in. The exhalation path is disposed between the breath discharge component and the tube.

Abstract: The accurate measurement of inspired and expired gas volume flow and gas composition are important in respiratory therapy. The invention provides a gas flow sensor for a ventilator comprising: a flow path extending between a first end that connects to a supply of gas and a second end that couples to a patient airway interface; and a constant temperature anemometer sensor arranged within the flow path between those ends. It further comprises a sampling port that may be coupled to a gas analyser device; and an orifice which is in fluid communication with the flow path and the sampling port so that, in use, gas may be drawn from the flow path for analysis, the gas being drawn from the flow path at a position located between the anemometer sensor and the first end.

Abstract: A sensor arrangement for detecting information indicative of a physiological substance in a body material of a physiological subject, wherein the sensor arrangement comprises a substrate, a first sensor structure connected to the substrate and being configured for sensing the physiological substance electrochemically, and a second sensor structure connected to the substrate and being configured for sensing the physiological substance by a luminescence detection.

Abstract: A hybrid model and diagnostic process for atrial fibrillation is provided. The present invention includes performing a combination of tests including an electrocardiogram signal analysis and a systolic pressure test. The results of the tests produce biomarkers for early detection of atrial fibrillation as well as for evaluating the severity of the disease.

Abstract: Methods and systems are presented for determining physiological information in a physiological monitor. A physiological signal (e.g., an EEG signal) received from a subject is wavelet transformed and first and second related features that vary in scale over time are identified in the transformed signal. First and second coupled ridges of the respective first and second related features may also be identified in the transformed signal. A non-stationary relationship parameter is determined and is indicative of the relationship between the first and second features and/or between the first and second ridges. Physiological information, which may be indicative of a level of awareness of a subject, is determined based on the non-stationary relationship parameter.

Abstract: A wrist watch style blood pressure monitor is configured to be mounted on a wrist of an examinee at ordinary times in order to measure and monitor blood pressure. The wrist watch style blood pressure monitor includes a blood pressure monitor main body which comprises a blood pressure display to display a blood pressure of the examinee. A band is coupled to the blood pressure display and is wound around the wrist of the examinee. An air chamber is provided at one side of the band and filled with air to compress a skin surface of the wrist. A pressure sensor is provided to measure the blood pressure from an aorta radialis when the air chamber compresses the aorta radialis.

Abstract: Certain implementations relate to an exhalation measurement device that is used in checking pulmonary function, diagnosing asthma, and may perform zero point correction accurately even when there is disturbance. The exhalation measurement device may comprise a flow regulator. The flow regulator comprises a first offset adjuster that puts an exhalation inflow component and an exhalation outflow component in a separated state and performs first offset adjustment of an inflow pressure sensor and an outflow pressure sensor, a voltage difference detector that puts the exhalation inflow component and the exhalation outflow component in a linked state and detects an output voltage difference after the first offset adjustment of the inflow pressure sensor and the outflow pressure sensor, and a second offset adjuster that uses the output voltage difference to perform second offset adjustment of the inflow pressure sensor.

Abstract: A sweat measuring device (1) comprising a sweat impermeable panel (40) and an adhesive skirt on one side thereof extending about its periphery to enable the panel to be secured to a user's skin is provided. The device covers a known area of a user's skin and traps sweat (42) produced by the skin under the panel. The panel (40) defines a reservoir in which sweat can accumulate and calibrations which may be associated with the reservoir to express the total sweat produced by the user as a function of the volume of sweat in the reservoir. The panel may be relatively stiff; formed by a plastics member and the skirt may extend integrally from the panel or be provided by an adhesive patch which covers the panel.

Abstract: An apparatus for collecting volatile compounds in human breath. The apparatus includes a device for discriminating between alveolar and non-alveolar portions of exhaled breath, a device for measuring volume of exhaled breath, a chamber with a piston or similar compressible device with clean internal services designed to collect a precise volume of alveolar breath, a pump to draw the exhaled breath from the chamber through at least one sorbent tube, a subsystem for introducing a clean gas into the chamber to expand it and for purging the tubing of the system, and a subsystem for selectively collecting a room air sample. A manifold is provided in the apparatus for receiving sorbent tubes and comprises an input block and output block, and a locking lever for actuating the input and output blocks linearly towards and away from each other and selectively locking them in a fully closed position.

Abstract: A CPU of a blood pressure measurement apparatus configured to be used while attached to a wrist of a measurement subject calculates an inclination angle formed by a forearm of the measurement subject with respect to a reference plane, and a rotation angle about an axis, where the forearm is used as the axis, of the blood pressure measurement device, based on information detected by an acceleration sensor, and uses the distance d between the radial artery and the ulnar artery that pass through the wrist, the inclination angle, and the rotation angle to determine the relative positional relationship between the radial artery and the ulnar artery. In accordance with the relative positional relationship, the CPU guides the measurement orientation of the measurement subject.

Abstract: An electronic apparatus includes an array of microphones for detecting audible sounds generated by a patient and for generating audio information representing the detected audible sounds, a first beamformer having a first adaptability speed and configured to generate first audio information and first noise information from the audio information, a second beamformer having a second adaptability speed which is slower than the first adaptability speed, the second adaptive beamformer configured to generate second audio information and second noise information from the audio information, an audio classification unit for generating audio classification information based on the first audio information, a head movement detection unit for generating head movement information based on at least one of the second audio information, the first noise information, and the second noise information, and a diagnosis unit for determining a sleep apnea diagnosis based on the audio classification information and the head movement

Abstract: An apparatus including a tubular channel having a pathway extending between a proximal end and a distal end of the tubular channel. The proximal end is configured to connect directly or indirectly to an end tidal CO2 monitor. The distal end has an opening. The apparatus further includes a detection member including a chamber disposed in fluid communication with the pathway of the tubular channel such that gas entering the tubular channel via the opening on the distal end passes into the chamber. A detection element is disposed within the chamber and includes a component that is sensitive to one or more systemic biomarkers such that, upon exposure to a predetermined concentration level of the one or more systemic biomarkers contained in the gas, a state of the detection element experiences a permanent alteration and the detection member indicates that the predetermined concentration level of the one or more systemic biomarkers is present in the gas.