Abstract: An integrated catheter placement system for accurately placing a catheter within a patient's vasculature is disclosed. In one embodiment, the integrated system comprises a system console, a tip location sensor for temporary placement on the patient's chest, and an ultrasound probe. The tip location sensor senses a magnetic field of a stylet disposed in a lumen of the catheter when the catheter is disposed in the vasculature. The ultrasound probe ultrasonically images a portion of the vasculature prior to intravascular introduction of the catheter. The ultrasound probe includes user input controls for controlling use of the ultrasound probe in an ultrasound mode and use of the tip location sensor in a tip location mode. In another embodiment, ECG signal-based catheter tip guidance is included in the integrated system to enable guidance of the catheter tip to a desired position with respect to a node of the patient's heart.

Abstract: An accurate real-time measurement of a displacement vector is achieved on the basis of the proper beamforming that require a short time for obtaining one echo data frame without suffering affections by a tissue motion. The displacement measurement method includes the steps of: (a) yielding ultrasound echo data frames by scanning an object laterally or elevationally using an ultrasound beam steered electrically and/or mechanically with a single steering angle over an arbitrary three-dimensional orthogonal coordinate system involving existence of three axes of a depth direction, a lateral direction, and an elevational direction; and (b) calculating a displacement vector distribution by implementing a block matching on the predetermined ultrasound echo data frames yielded at more than two phases.

Abstract: A detector of an embodiment includes a plurality of photomultipliers, a signal line, and identifying circuitry. The photomultipliers each convert light converted from radiation into an electric signal and output the electric signal. The signal line has a first path and a second path through which the electric signal passes and that have different lengths for each of the photomultipliers. The identifying circuitry identifies the photomultiplier that outputs the electric signal by a time difference between the electric signal passing through the first path and the electric signal passing through the second path.

Abstract: Provided are an ultrasonic diagnostic apparatus and a method of operating the same. The ultrasonic diagnostic apparatus includes: a first ultrasonic transceiver that transmits an ultrasonic signal and receives a first echo signal that is reflected, through a deactivated probe from among a plurality of probes; a gel detector that determines whether gel is applied on the deactivated probe based on the received first echo signal; and a controller that activates the deactivated probe when it is determined that the gel is applied on the deactivated probe.

Abstract: Certain aspects relate to apparatuses and techniques for non-invasive optical imaging that acquires a plurality of images corresponding to both different times and different frequencies. Additionally, alternatives described herein are used with a variety of tissue classification applications, including assessing the presence and severity of tissue conditions, such as burns and other wounds.

Abstract: An ultrasound system and method that can include: a receive beamformer configured to receive signals from a transducer; a processor coupled to the receive beamformer, the processor configured to: analyze echo data reflected from a region of interest, the echo data elicited by a transmitted pulse sequence; using the echo data, determine a central tendency of a signal magnitude from regions of adherent microbubbles over time within the region of interest; determine a time series of the signal magnitude; using the time series, determine an initial signal magnitude parameter; obtain a saturated signal parameter and a residual signal parameter using the time series; and determine a relative indication of information indicative of the residual signal magnitude versus the saturated signal magnitude.

Abstract: An image processing method enables an elasticity image of a body including a cavity to be produced on the basis of the material(s) forming the body, wherein the method includes the steps of: receiving a deformation image illustrating a field of movement of the points of the body on the basis of a pressure difference in the body, estimating a shape function of the body from the deformation image, calculating an elasticity image of the body on the basis of the shape function, of the pressure difference and of the deformation image.

Abstract: The present invention generally relates to paramagnetic contrast agents and a Dynamic Contrast Enhanced-MRI method for the non-invasive estimation of the delivery of a macromolecular anticancer drug or pro-drug within pathological tissues and, especially, in solid tumors and for the optimization of anticancer therapies.

Abstract: A subject-information acquisition apparatus includes a light source; a holding member configured to hold a subject so as to surround the subject; at least one transducer configured to receive an acoustic wave generated by irradiating the subject with light from the light source; and a signal processing unit configured to obtain distribution information using a received signal output from the transducer. The holding member includes a marker that absorbs the light and generates an acoustic wave.

Abstract: Systems and methods are disclosed for locating the parathyroid. In one aspect, temporal variation among a plurality of images is evaluated and at least one image is enhanced according to the temporal variation. The image may be enhanced to one or both of reduce conspicuity of the thyroid gland and enhance conspicuity of the parathyroid gland. Some of the plurality of images may be adjusted in order to align representations of a target portions. Adjustments may be based locations of one or more organs or one or more artificial markers affixed to a living body in the plurality of images. A local positioning system (LPS), GPS, or other locating system may be used to position a living body, align the plurality of images, or to guide the positioning of objects relative to the living body. An elastomeric gel marker for imaging applications is also disclosed.

Abstract: An optical coherence tomography (“OCT”) system that includes a planarizing transparent material is provided. The OCT system includes an OCT probe comprising: a body having a distal end and a proximal end; a positioner adapter located at the proximal end; a connector to an OCT analysis device, the connector located at the proximal end; and, an OCT scan lens located at the distal end. The OCT system further includes: a transparent material configured to planarize tissue at a scan plane of the OCT scan lens.

Abstract: Disclosed is a pullback system, which has a simplified and miniaturized structure and an advanced function. The pullback system includes a central unit, which includes a rotation transducer part that rotates, and a stretchable part that is connected to a side of the rotation transducer part to rotate together with the rotation transducer part and that has a stretchable property, and a first unit rotatably coupled to a portion of the central unit. As the first unit moves in a first direction oriented from the rotation transducer part to the stretchable part or in a second direction opposite to the first direction, the stretchable part contacts or stretches.

Abstract: The present invention relates to a method of diagnosing, or providing a prognosis to, or for providing the likelihood of developing, malignant melanoma in a subject, the method comprising the steps of: (a) measuring two or more markers in blood perfusion dynamics at and/or around a skin lesion site; and (b) determining if the two or more markers is different to a normal value. The invention also relates to a device for diagnosing/providing a prognosis to/for malignant melanoma in a subject.

Abstract: Embodiments of the present invention provide an ultrasound scanner equipped with an image data processing unit that can perform adaptive parameter optimization during image formation and processing. In one embodiment, an ultrasound system comprises a channel data memory to store channel data obtained by digitizing ultrasound image data produced by an image scan; an image data processor configured to process the stored channel data in the memory to reconstruct an ultrasound image for each of a plurality of trial values of at least one parameter to be optimized; and a parameter optimization unit configured to evaluate an image quality of the reconstructed ultrasound image for each trial value of the at least one parameter, and to determine the optimized value of the at least one parameter based on the evaluated image quality.

Abstract: There are provided an ultrasound diagnostic apparatus management system and a method of controlling the ultrasound diagnostic apparatus management system. The ultrasound diagnostic apparatus management system may include a diagnosis unit including an acoustic module and a connecting unit of the diagnosis unit; a rearrangement unit including a connecting unit for rearrangement in which the connecting unit of the diagnosis unit is docked and a power supply unit for rearrangement; a detecting unit configured to measure a capacitance of the acoustic module; and a control unit configured to control such that the power supply unit for rearrangement applies a voltage for rearrangement to the acoustic module when the measured capacitance is a predetermined value or less.

Abstract: A matrix array probe including a transducer array and integrated circuitry coupled to the transducer elements dissipates heat generated by the array and integrated circuitry through the cover of the transducer probe. A pump in the probe connector pumps fluid through a closed loop system including inbound an outbound fluid conduits in the cable. The fluid conduits in the cable are separated by the cable electrical conductors for the probe. The heat transfer in the probe is done by a heat exchanger in the transducer backing block. Additional cooling may be provided by metal to metal contact with a chiller in the ultrasound system.

Abstract: A matrix array probe including a transducer array and integrated circuitry coupled to the transducer elements dissipates heat generated by the array and integrated circuitry through the cover of the transducer probe. A pump in the probe connector pumps fluid through a closed loop system including inbound an outbound fluid conduits in the cable. The fluid conduits in the cable are separated by the cable electrical conductors for the probe. The heat transfer in the probe is done by a heat exchanger in the probe spaceframe or transducer stack backing block and may use a Peltier device. Additional cooling may be provided by metal to metal contact with a chiller in the ultrasound system.

Abstract: Skin monitoring device for application near the skin includes a processing circuit and at least one photosensor configured to detect at least one approximate wavelength of light reflected and/or emitted by the skin. A signal receiving circuit receives signals from the photosensor.

Abstract: A device and method for measuring prosthetic or orthotic slip is presented. An optical sensor device is attached to the prosthesis or orthosis and measures the amount of relative motion between the prosthetic socket and the residual limb surface or between the orthosis and the affected body part. The sensor device is comprised of an optical sensor, a light source, a processing unit and a power source contained within a housing. A system for measuring multidirectional prosthetic or orthotic slip using the sensor device and automatically adjusting the fit of the prosthetic based on a determined threshold is also presented.

Abstract: Imaging, testing and/or analysis of subjects are facilitated with a capillary-access approach. According to an example embodiment, a capillary is implanted into a specimen and adapted to accept an optical probe to facilitate optical access into the specimen. In some applications, the capillary is implanted for use over time, with one or more different probes being inserted into the capillary at different times, while the capillary is implanted. Certain applications involve capillary implantation over weeks, months or longer. Other applications are directed to the passage of fluid to and/or from a sample via the capillary. Still other applications are directed to the passage of electrical information between the sample and an external arrangement, via an implanted capillary.