Patents Examined by Angeline Premraj
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Patent number: 10092239Abstract: A biosensor is proposed for insertion into the subcutaneous tissue of a user wherein the biosensor includes at least one flexible substrate and at least one electrode on at least one surface of the substrate and at least one contacting element. The contacting element is connected to the electrode. The substrate has at least one kink, at which the substrate is at least partly kinked such that the surface is subdivided into at least two interconnected outer surfaces.Type: GrantFiled: July 31, 2017Date of Patent: October 9, 2018Assignee: Roche Diabetes Care, Inc.Inventors: Stephan-Michael Frey, Oliver Kube
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Patent number: 10010690Abstract: An endotracheal tube apparatus is provided which comprises an endotracheal tube insertable into a trachea of a patient, wherein the endotracheal tube has a sidewall and includes a first passageway, wherein the first passageway is a ventilation passageway to provide ventilation to the patient; a fluid sampling port connected to the sidewall of the endotracheal tube; the fluid sampling port including a fluid sampling passageway, the fluid sampling passageway to obtain a fluid sample comprising one or more gases exhaled from the patient; and the fluid sampling port including a connector to connect the fluid sampling port to an analyzer to detect a presence of carbon dioxide gas in the fluid sample.Type: GrantFiled: March 13, 2014Date of Patent: July 3, 2018Assignee: Monitoring for Life, LLCInventor: Scott P. Geraghty
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Patent number: 9974477Abstract: A renal denervation catheter includes a catheter shaft, at least one ablation member, and a sensor, and is operable to perform a renal denervation procedure. The catheter shaft includes a distal end portion insertable into a renal artery. The at least one ablation member is positioned at the distal end portion of the catheter shaft and operable to ablate renal nerves along a wall of the renal artery. The sensor provides information that correlates to blood flow in the renal artery. A change in blood flow rate in the renal artery resulting from the ablation is indicative of the efficacy of the renal denervation procedure.Type: GrantFiled: March 15, 2013Date of Patent: May 22, 2018Assignee: ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.Inventors: Martin Cholette, Sergio Shkurovich
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Patent number: 9968304Abstract: A system and method are disclosed for detecting a vasoactive agent in patient's bloodstream. In one embodiment, an input signal is received that is associated with arterial blood pressure. A change of an arterial blood pressure parameter over time is determined. A vasoactive agent is then automatically detected using the determined change. In another embodiment, a waveform associated with an arterial blood pressure signal can be received. A parameter associated with the received waveform is calculate. Then the calculated parameter can be used to determine the presence of a vasoactive agent. In yet another embodiment, detection of a vasoactive agent in any of the other embodiments can be used in a calculation of a hemodynamic parameter, such as cardiac output, stroke volume, systemic vascular resistance, stroke volume variation, cardiac index, stroke volume index, systemic vascular resistance index, vascular compliance, and vascular tone.Type: GrantFiled: October 5, 2012Date of Patent: May 15, 2018Assignee: Edwards Lifesciences CorporationInventors: Zhongping Jian, Feras Hatib
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Patent number: 9962094Abstract: A vascular endothelial function inspection apparatus includes a first cuff that is mounted to a first part of a subject, a cuff pressure control unit that controls a pressure applied to the first cuff, a pressure sensor that is connected to the first cuff, a cuff pressure detection unit that detects a cuff pressure from an output of the pressure sensor, a pulse wave detection unit that detects pulse waves from the output of the pressure sensor, a blood pressure measuring unit that measures a blood pressure value based on the cuff pressure and the pulse waves, a storage unit that stores therein an elasticity index value indicating an elasticity of a blood vessel of the subject, and an analysis unit that performs data processing for evaluating an endothelial function of the blood vessel.Type: GrantFiled: February 26, 2015Date of Patent: May 8, 2018Assignee: Nihon Kohden CorporationInventors: Yoshinobu Ono, Tsuneo Takayanagi
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Patent number: 9924878Abstract: Methods and apparatus for determining blood flow in tissue are disclosed. The methods and apparatus are used to establish a baseline for both thermal properties of the tissue and non-physiologic conditions. Periodic changes in either or both constituents of the baseline are determined and, when the changes correspond to a need for a new baseline, a new baseline is established.Type: GrantFiled: March 15, 2013Date of Patent: March 27, 2018Inventors: H. Frederick Bowman, Gregory T. Martin
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Patent number: 9907491Abstract: Subject matter disclosed herein relates to monitoring and/or controlling levels of an analyte in bodily fluid. In particular, estimation of a concentration of the analyte in a first physiological compartment based upon observations of a concentration of the analyte in a second physiological compartment may account for a latency in transporting the analyte between the first and second physiological compartments.Type: GrantFiled: October 22, 2012Date of Patent: March 6, 2018Assignee: Medtronic Minimed, Inc.Inventors: Xialong Li, Brian T. Kannard, Rajiv Shah
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Patent number: 9877633Abstract: A bleeding detection unit in a surgical system processes information in an acquired scene before that scene is presented on a display unit in the operating room. For example, the bleeding detection unit analyzes the pixel data in the acquired scene and determines whether there are one or more initial sites of blood in the scene. Upon detection of an initial site of blood, the region is identified by an initial site icon in the scene displayed on the display unit. In one aspect, the processing is done in real-time which means that there is no substantial delay in presenting the acquired scene to the surgeon.Type: GrantFiled: July 22, 2013Date of Patent: January 30, 2018Assignee: Intuitive Surgical Operations, IncInventors: Wenyi Zhao, Catherine J. Mohr, Jonathan M. Sorger
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Patent number: 9872633Abstract: Sensors are disclosed that detect whether a cannula is properly inserted to its full depth in a subject's skin. The sensors may be used with a blood glucose monitor, or with a continuous insulin infusion pump, infusion set, or other system involving intermittent or continuous testing and/or drug delivery.Type: GrantFiled: September 29, 2014Date of Patent: January 23, 2018Assignee: Becton, Dickinson and CompanyInventors: Amit Limaye, Keith Knapp, Elizabeth Nelson, Patrick Allen, Amanda Masotta
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Patent number: 9861311Abstract: A medical device including a probe configured to be orally inserted into a lumen extending into the thorax of the subject, a plurality of electrodes, and a control circuit. The probe includes a first electrode. The plurality of electrodes includes at least one second electrode and at least one third electrode configured to be disposed externally on the thorax of the subject on a first side of a sternum of the subject and a second side of the sternum of the subject, respectively, the second side opposite the first side. The control circuit is electrically coupled to the first electrode and the at least one second and third electrodes and configured to measure an impedance between the first electrode and each of the at least one second and third electrodes and determine a ratio of arterial blood volume relative to venous blood volume based upon the measured impedance.Type: GrantFiled: August 1, 2013Date of Patent: January 9, 2018Assignee: ZOLL MEDICAL CORPORATIONInventors: Gary A. Freeman, Ulrich Herken, Christopher L. Kaufman
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Patent number: 9855010Abstract: Systems and methods for analyzing respiratory gas are configured to function in both divertive and non-divertive configurations. A mainstream gas analyzer housing economically and removably couples with a sidestream gas sampling component.Type: GrantFiled: April 2, 2012Date of Patent: January 2, 2018Assignee: Koninklijke Philips N.V.Inventor: Michael Brian Jaffe
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Patent number: 9844343Abstract: A biosensor is proposed for insertion into the subcutaneous tissue of a user wherein the biosensor includes at least one flexible substrate (2) and at least one electrode (5) on at least one surface (9) of the substrate and at least one contacting element (3). The contacting element is connected to the electrode. The substrate has at least one kink (4), at which the substrate is at least partly kinked such that the surface is subdivided into at least two interconnected outer surfaces (9a, 9b, 9c).Type: GrantFiled: June 28, 2013Date of Patent: December 19, 2017Assignee: Roche Diabetes Care, Inc.Inventors: Stephan-Michael Frey, Oliver Kube
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Patent number: 9833171Abstract: In a multi-sensor system and method of monitoring vital body signals during movement of a body of a human or an animal, acceleration sensors are placed at body locations in such a way that an acceleration angle change induced by the vital body signals differs between the at least two acceleration sensors. The retrieval of the vital body signals is achieved by extracting a wanted vital body signal based on measurement results from multiple sensors that may be motion contaminated. Three retrieval schemes are proposed, each with preferred sensor locations that provide optimal performance of retrieving the vital body signal(s).Type: GrantFiled: July 27, 2011Date of Patent: December 5, 2017Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Bin Yin, Steven Antonie Willem Fokkenrood, Haris Duric, Teun Van Den Heuvel
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Patent number: 9763626Abstract: Embodiments of the present invention are directed a system using a microphone and a mobile computer device comprising a transducer through which a user is to exhale or inhale; the transducer is configured and operable to convert the spirometric flow rate into an audible signal having an audio frequency responsive to the spirometric flow rate, wherein the transducer comprises a rotor including a plurality of rotor blades configured to rotate the rotor responsive to a spirometric flow; wherein the microphone is external to the transducer and is adapted to detect the audible signal having the audio frequency and to convert the audible signal to a corresponding electrical signal having the audio frequency.Type: GrantFiled: May 5, 2016Date of Patent: September 19, 2017Assignee: BREATHE.ME LTD.Inventors: Lior Gonnen, David Groberman, David Solomon, Rahav Cohen
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Patent number: 9763610Abstract: A medical monitoring unit for continuously monitoring a glucose value and a lactate value is provided. The monitoring unit comprises: a display unit, a first unit adapted to: receive a glucose/lactate/pyruvate signal based on a measured glucose/lactate/pyruvate value, transform the glucose signal into a graphically displayable glucose/lactate/pyruvate signal, and transmit the graphically displayable glucose/lactate/pyruvate signal to the display unit of the monitoring unit, and a second unit adapted to: receive a glucose/lactate/pyruvate signal based on a measured glucose/lactate/pyruvate value, transform the glucose/lactate/pyruvate signal into a graphically displayable glucose/lactate/pyruvate signal, and transmit the graphically displayable glucose/lactate/pyruvate signal to the display unit of the monitoring unit.Type: GrantFiled: December 22, 2010Date of Patent: September 19, 2017Assignee: MAQUET CRITICAL CARE MBInventors: Anton Karlsson, Anders Carlsson, Andreas Broman
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Patent number: 9730645Abstract: The present disclosure relates to a method and system for identifying potential condition onset based upon a combination of Heart Rate Variability (HRV), Respiratory Rate Variability (RRV) and/or confounding factors. The present method and system may involve data collection, a temporal abstraction (TA)-based approach, and data analysis to identify potential condition onset in patients. The present method and system may generate and amend a classification scheme to be operable to determine that a patient is facing potential condition onset. The present method and system may further be operable to provide clinical decision making support. Embodiments of the present method and system may be operable to identify trends, such as temporal patterns, and to undertake a variety of analyses of collected and/or TA data to provide indicators, and determinations of potential condition onset in patients.Type: GrantFiled: March 19, 2012Date of Patent: August 15, 2017Inventors: Carolyn Patricia Mcgregor, Christina Anne Catley, Andrew Gibson James
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Patent number: 9730633Abstract: Immediately after airway placement and/or following any patient transfer, an automated program may be activated in a CO2 monitoring device to provide an airway device placement check. The automated program needs time to determine if the airway placement has been successful or not. During analysis of CO2 respiration data by the program, real-time feedback is displayed to the user as soon as the airway check program is activated until the time that a final decision on the success of airway placement is made. The real-time feedback displays one or more indicators of the progress of the program toward a determination of a successful or failed placement.Type: GrantFiled: February 21, 2012Date of Patent: August 15, 2017Assignee: Koninklijke Philips N.V.Inventors: Saeed Babaeizadeh, Eric Helfenbein, Sophia Huai Zhou
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Patent number: 9724017Abstract: A single respiratory cycle flow limitation detection method is disclosed. A patient gas delivery signal is received from one or more sensors in pneumatic communication with a ventilation source and a patient ventilation interface to a patient airway. The patient gas delivery signal is representative of a measure of therapeutic gas being delivered to the patient airway at a given time instant, and spans the single patient respiratory cycle. A second derivative of the patient gas delivery signal is generated and a total number of zero crossings therein are counted. These zero crossings are representative of an inflection change in the patient gas delivery signal. A flow limitation indication corresponding to the identified flow limitation is generated when there are at least two zero crossings in the second derivative of the patient gas delivery signal. An angle of deformation representing early, late, or mid-cycle obstruction onsets is generated.Type: GrantFiled: July 3, 2013Date of Patent: August 8, 2017Assignee: Breathe Technologies, Inc.Inventors: Leonardo Alberto Baloa Welzien, Samir S. Ahmad
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Patent number: 9655533Abstract: A method for generating a sampled plethysmograph data, includes measuring a plethysmograph waveform indicative of a first cardiac cycle and a second cardiac cycle, each cycle including a systolic waveform and a diastolic waveform. The method further includes estimating a first start time and a first duration for the systolic waveform of the first cardiac cycle and computing a plurality of amplitudes at a plurality of time instants for the first duration. The method further includes determining a second start time and a second duration of the systolic waveform of the second cardiac cycle. The method also includes assigning the second cardiac cycle, the second start time, and the second duration to the first cardiac cycle, the first start time, and the first duration respectively. The method further includes iteratively performing the steps of measuring, estimating, computing, determining and assigning for the plurality of cardiac cycles acquired sequentially in time.Type: GrantFiled: November 13, 2013Date of Patent: May 23, 2017Assignee: General Electric CompanyInventors: Stanislava Soro, SM Shajedul Hasan, Jason Harris Karp
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Patent number: 9622709Abstract: Systems and methods are provided for monitoring a patient during a procedure. A physiological parameter of a patient is monitored during a procedure at an associated sensor. Respective cumulative times are measured for which the monitored physiological parameter of the patient meets each of a plurality of threshold values during the procedure. A risk metric is calculated for the patient, representing an effect of monitored physiological parameter on a patient outcome related to the procedure from the measured cumulative times for which the monitored physiological parameter of the patient met each of the plurality of threshold values.Type: GrantFiled: October 11, 2013Date of Patent: April 18, 2017Assignee: The Cleveland Clinic FoundationInventors: Wolf H. Stapelfeldt, Marc R. Reynolds, Bhaswati Ghosh