Abstract: Techniques for determining the trajectory of a one or more dorsal roots and utilizing the trajectories to improve a spinal cord stimulation model are disclosed. A first improvement constructs a target stimulation field along a path that is parallel with the determined trajectory that is nearest to a specified desired location of stimulation. An allocation of stimulation among the electrodes to mimic the target field is computed. A second improvement models a response of neural elements at evaluation positions that are parallel with the trajectories based on the electric field that is generated for the computed allocation of stimulation among the electrodes. The stimulation amplitude is adjusted based on the neural element modeling to maintain stimulation intensity, and the stimulation amplitude and allocation of stimulation among the electrodes are compiled into an electrode configuration that is communicated to a neurostimulator.

Abstract: The present disclosure discusses a nerve cuff that includes a thin-film elastic mesh with an integrated array of electrodes. The nerve cuff can wrap around a human carotid artery or other tissue to stimulate the autonomic nervous system. The nerve cuff can include a housing that secures the mesh to the carotid artery or other tissue.

Abstract: The exemplified technology facilitates de-noising of magnetic field-sensed signal data (e.g., of an electrophysiological event) using signal reconstruction processes that fuse the magnetic field-sensed signal data with another sensed signal data (e.g., voltage gradient signal data) captured simultaneously with the magnetic field-sensed signal data. To this end, the purely algorithmic processing technique beneficially facilitates removal and/or filtering of noise from a sensor lead of a noisy captured source and rebuilds the signal for that lead from information simultaneously obtained from other leads of a different source. In some embodiments, a data are fused via a sparse approximation operation that uses candidate terms based on Van der Pol differential equations.

Abstract: A subretinal prosthetic device includes a substrate provided under a retina, a return electrode for receiving a current such that a ground is formed on the substrate, a plurality of stimulating electrodes provided on the substrate and for generating an active potential to an optic nerve in response to external visual information projected onto the retina, and a switch for controlling the current between each of the plurality of stimulating electrodes and the return electrode. The switch is connected between the plurality of stimulating electrodes and the return electrode to ground the plurality of stimulating electrodes to the return electrode in response to an on or off control signal.

Abstract: The invention resides in a pattern laser comprising a plurality of laser devices each emitting a treatment laser beam into an optical fibre of an optical fibre bundle. An optical coupling module is associated with each laser device and each optical fibre for coupling a treatment laser beam into the associated optical fibre. A controller controls the operation of the laser devices by selectively turning on or off one or more of the laser devices so as to form a laser treatment pattern at an end of the fibre bundle away from the laser devices. A delivery system images the output from the fibre bundle to a treatment zone.

Abstract: A vital-sign detection system is provided. The vital-sign detection system includes a vital-sign detection device and a controller. The vital-sign detection device is enabled to detect a vital-sign of a user. The controller determines whether the gets in the bed and controls the vital-sign detection device to switch to a disabled mode from a first enabled mode in response to the user getting in the bed. During a period when the vital-sign detection device is in the disabled mode, the controller determines whether the user falls asleep. In response to the user falling asleep, the controller controls the vital-sign detection device to switch to a second enabled mode from the disabled mode.

Abstract: Techniques, devices, and systems for isolating, by isolation circuitry connected to a power source, a voltage from the power source, receiving, by sensing circuitry, the isolated voltage, receiving, by the sensing circuitry, a reference voltage from an implantable reference electrode via a reference node, and sensing, by the sensing circuitry, the biomedical signal with two or more implantable sensing electrodes using the isolated voltage with respect to the reference voltage.

Abstract: A micro-scale implantable bioelectronic medical device system that allows multichannel neurostimulation of peripheral nerve bundles so to affect a more localized and specific control over neuromodulation of body tissues and organs. Such systems can be used in medical therapeutic applications for the treatment of a wide variety of disorders of the human body and may be applied in the growing field of medical neuromodulation. Systems and processes may also provide a way of interfacing to nerve and muscle for purposes of the control of advanced robotic prosthetics as well as man-machine interfaces. Apparatus, systems and processes may be adapted in various embodiments to the stimulation of brain and other bioelectrically excitable tissues in the human body as well.

Abstract: Cardiac catheterization is conducted with a probe having a plurality of sensors. The heart is displayed as a first graphic image. Signals from the sensors are processed according to a predefined algorithm to generate respective outputs, A region on the first graphic image that is less than all of the first graphic image is selected according to locations of the sensors, and values derived from outputs of the sensors are displayed on the selected region as a second graphic image. Thereafter, the second graphic image is removed and replaced by an updated version.

Abstract: The present disclosure relates to an eyewear phototherapy device for providing skin cosmetology to the skin surrounding the eyes. The device includes a main spectacle frame having a left supporting member and right supporting member, each including at least one housing assembly extending outward from the each supporting member and facing towards the inner portion of the supporting member. Each of the housing assemblies includes an LED light board, attached to the inner side of the respective housing assembly, which is adapted to emit light energy, a transparent silicone cover attached on the LED light board for protecting direct contact between the LED light board and human skin, a protective element which is adapted to spread the LED emissions around a human eye and provide protection to the human eye from the LED emissions.

Abstract: A compact system for performing laser ophthalmic surgery is disclosed. The systems and methods may be used to measure corneal thickness or other anatomy to prepare a treatment plan for any of numerous treatments, such as LASIK, PRK, intra stromal lenticular lens incisions, cornea replacement, or any other treatment. By using a reduced power femtosecond laser backscatter may be measured to calculate distances such as distances between an interior boundary and an exterior boundary of a cornea or other tissue.

Abstract: Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, an intravascular propeller is installed into the descending aorta and anchored within via an expandable anchoring mechanism. The propeller and anchoring mechanism may be foldable so as to be percutaneously deliverable to the aorta. The propeller may have foldable blades. The blades may be magnetic and may be driven by a concentric electromagnetic stator circumferentially outside the magnetic blades. The stator may be intravascular or may be configured to be installed around the outer circumference of the blood vessel. The support may create a pressure rise between about 20-50 mmHg, and maintain a flow rate of about 5 L/min. The support may have one or more pairs of contra-rotating propellers to modulate the tangential velocity of the blood flow. The support may have static pre-swirlers and or de-swirlers.

Abstract: The invention provides an excimer laser system including a means for calibrating laser output to compensate for increased variation in laser optical fibers.

Abstract: A wireless optogenetic device in proximity to a neural cell of a subject includes a body configured to hold light transducing materials arranged to up-convert electromagnetic radiation in infrared or near-infrared spectrum into light in the visible spectrum to affect activity of the neural cell. The body allows electromagnetic radiation in infrared or near-infrared to reach the light transducing materials. A radiation system includes a radiation probe for irradiating a wireless optogenetic device with electromagnetic radiation in infrared or near-infrared spectrum from a radiation source. The system further includes a movement mechanism for moving the radiation probe, a detector for detecting a location of the wireless optogenetic device, and a controller for controlling the movement mechanism based on the detected location of the wireless optogenetic device such that the radiation probe is arranged to irradiate the wireless optogenetic device at the detected location with the electromagnetic radiation.

Abstract: A fetal scalp monitor is disclosed that enables a medical professional to monitor the well-being of a fetus in utero. The fetal scalp monitor has a main body, with a central core having a temperature sensor, conductive dome, grounding ring, and tocodynamometer. The main body also has at least one adhesive portion to facilitate the attachment of the device onto the scalp of a fetus, and a plurality of concentric rings to militate against amniotic fluids from entering the adhesive portion. The vital signs of the infant and conditions inside the uterus are then transmitted, either wired or wirelessly, to a fetus monitoring device.

Abstract: A heart pacemaker according to the present invention includes a generator configured to generate nonlinear electrical energy using a friction element and an energy harvester configured to sequentially store the generated nonlinear electrical energy in multi-stage multiple energy storages and supply the electrical energy stored in the multiple energy storages.

Abstract: Apparatus and methods for managing pain uses separate varying electromagnetic fields, with a variety of temporal and amplitude characteristics, which are applied to a particular neural structure to modulate glial and neuronal interactions as a mechanism for relieving chronic pain. In another embodiment, a single composite modulation/stimulation signal which has rhythmically varying characteristics is used to achieve the same results as separate varying electromagnetic fields. Also, disclosed is an apparatus and method for modulating the expression of genes involved in diverse pathways including inflammatory/immune system mediators, ion channels and neurotransmitters, in both the Spinal Cord (SC) and Dorsal Root Ganglion (DRG) where such expression modulation is caused by spinal cord stimulation or peripheral nerve stimulation using the disclosed apparatus and techniques.

Abstract: A system (1) for treating and monitoring the condition of an eye (6) includes a light source, preferably a non-lasing LED (2), for irradiating the eye at a wavelength sufficient to reverse eye damage. The system also includes an excitation light source, preferably a non-lasing LED (4), for exciting fluorescence in the eye and a detector (22) for detecting fluorescence stimulated by the excitation LED (4). The system may also include a second non-lasing light source, preferably a non-lasing LED, for irradiating the eye; and a detector for detecting scatter of light from the eye. Methods for monitoring, diagnosis and treatment of eye conditions such as cataracts are also provided.

Abstract: Some embodiments include processing data via an executable file on a monitor to reduce the dimensionality of the data being transmitted over the wireless network. The output of the executable file also encrypts the data before being transmitted wireless to a remote server. The remote server receives the transmitted data and makes likelihood inferences based on the recorded data.

Abstract: A system and method for emitting a wavelength of energy internal to a medium or internal to a human or animal subject, and methods for using the system in the treatment of a condition, disorder, or disease. The system includes 1) a source configured to produce an initiation signal penetrating at least a part of the medium or the human or animal subject and 2) an insertion device having an electronics assembly unit. The assembly unit includes 1) an emitter configured to emit the wavelength of energy of a predetermined type to treat a disease or disorder in the human or animal subject or to produce a change in the medium and 2) a receiver that receives the signal.