Abstract: This invention provides for a dermal repair system including a dermal repair device which is configured to be placed on the skin of a user. The dermal repair device is in the form of a removable silicone sheet which can be securely fixed in place and re-used after cleaning etc. The silicone sheet includes sheet sections and a housing section into which a rechargeable control unit can removably be inserted. Waveguides in the form of a dimple teardrop pattern are provided for directing radiation or light to distal ends of the sheet. The control unit includes a low-level radiation or light source from which radiation or light is directed along the sheet for a therapy regimen to treat closed wounds and scars, such as, C-section and breast surgery closed wounds and scars to improve healing and scar appearance. The system further comprises a recharging station configured for recharging the control unit.

Abstract: An organ evaluation device, system, or method is configured to receive electrophysiological data from a patient or model organism and integrates the data in a computational backend environment with anatomical data input from an external source, spanning a plurality of file formats, where the input parameters are combined to visualize and output current density and/or current flow activity having ampere-based units displayed in the spatial context of heart or other organ anatomy.

Abstract: An implantable pump system is provided, including an implantable blood pump suitable for use as a partial support assist device, the system further including an extracorporeal battery and a controller coupled to the implantable pump, and a programmer selectively periodically coupled to the controller to configure and adjust operating parameters of the implantable pump. The implantable pump includes a flexible membrane coupled to an electromagnetic actuator including a magnetic assembly and electromagnetic assembly, so that when the electromagnetic assembly is energized, the electromagnetic assembly causes wavelike undulations to propagate along the flexible membrane to propel blood through the implantable pump. The controller may be programmed by a programmer to operate at frequencies and duty cycles that mimic physiologic flow rates and pulsatility while operating in an efficient manner that avoids thrombus formation, hemolysis and/or platelet activation.

Abstract: A method of stimulation of a body of a user for therapeutic effects having the steps of providing a stimulator connected to a garment. The garment is connected to a first predetermined location on a user's body. Positioning a user's body at a predetermined orientation. The next step includes applying stimulation from the stimulator to the first predetermined location on the user's body so that therapeutic effects are experienced at both the first predetermined location and at a second predetermined location of a user's body.

Abstract: A laser device for the selective treatment of acne comprising: a laser source (1) terminating in an optical collimator (2), which supplies a laser beam; said laser source (1) comprises a switch (13) which allows impulses of said laser beam with pre-defined duration to be transmitted; an opto-mechanical interface (3) comprising a lens (4) focusing the laser beam received from the optical collimator (2); an optical fibre (5) connected to said opto-mechanical interface (3); characterized in that said optical fibre (5) has a length greater than 15 m; and said device comprises a handpiece (10) connected to said optical fibre (5) where said handpiece (10) comprises an optical zoom system (11) which allows the diameter of the laser beam emerging from said handpiece (10) to be varied from 0.5 mm to 5 mm.

Abstract: A lipolysis radiation paddle (2) comprises a plurality of lipolysis radiation transducers (14) mounted in a base (20). The base (20) has a lower portion (21), and a pair of side portions (26) extending upwardly from respective sides of the lower portion (21). The lower portion (21) is shaped to fit under the jaw (51) of a user (50) of the paddle (2), and has a front end (22) shaped to receive the chin (52) of the user (50). The side portions (26) are each shaped to extend to and along respective sides of the jawline (53) of the user (50). The transducers (14) are directed inwardly towards the skin in proximity to the paddle (2).

Abstract: The present invention is an improved system for use of eye tracking including spatial mapping percepts in a visual prosthesis by presenting an electrically induced precept through a visual prosthesis, requesting a subject look to the direction of the percept and tracking their eye movement. Eye movement is both faster and more accurate than asking a visual prosthesis user to point to the location of a percept. This method can be beneficial in a retinal prosthesis, but is particularly useful in a cortical visual prosthesis where visual cortex does not match the retinotopic map. Methods are presented for calibrating an eye tracker. Eye tracking hardware may also be used for blanking video information base on the subject's natural blink reflex.

Abstract: Neuromodulation systems are described comprising a signal generator and at least one electrode. The at least one electrode can be configured to deliver a stimulation to a mammal, wherein the stimulation includes a biphasic signal and an overlapping high frequency pulse thereby inducing voluntary movement in the individual. Methods of administering the stimulation are also described.

Abstract: A system for identifying arrhythmias based on cardiac waveforms includes a storage system storing a trained deep neural network system, wherein the trained deep neural system includes a trained representation neural network and a trained classifier neural network. A processing system is communicatively connected to the storage system and configured to receive cardiac waveform data for a patient, identify a time segment in the cardiac waveform data, and transform the time segment into a spectrum image. The processing system is further configured to generate, with the representation neural network, a latent representation from the spectrum image, and then to generate, with the classifier neural network, an arrhythmia classifier from the latent representation.

Abstract: Electrocardiograms can be analyzed in the time-frequency domain, following conversion into time-frequency maps, to determine characteristics or features of various waveforms, such as waveform morphology and/or the amplitude(s) and location(s) (in time and/or frequency) of one or more extrema of the waveform. Based on comparison of the extrema against thresholds and/or against each other, disease conditions may be determined.

Abstract: Apparatus and methods for managing pain uses separate varying electromagnetic fields, with a variety of temporal and amplitude characteristics, which are applied to a particular neural structure to modulate glial and neuronal interactions as a mechanism for relieving chronic pain. In another embodiment, a single composite modulation/stimulation signal which has rhythmically varying characteristics is used to achieve the same results as separate varying electromagnetic fields. Also, disclosed is an apparatus and method for modulating the expression of genes involved in diverse pathways including inflammatory/immune system mediators, ion channels and neurotransmitters, in both the Spinal Cord (SC) and Dorsal Root Ganglion (DRG) where such expression modulation is caused by spinal cord stimulation or peripheral nerve stimulation using the disclosed apparatus and techniques.

Abstract: Disclosed are methods of predicting the risk of developing a neurological disorder in a mammalian subject and methods of use of this profile for providing neuroanalytical services for an end user. Also disclosed is a system comprising a processor and a memory having a neurodiagnostic algorithm and plurality of data sets, the processor being capable of reading the data sets, executing the neurodiagnostic algorithm, and deriving a risk profile therefrom.

Abstract: Systems and methods for monitoring patient for syncope are discussed. A syncope monitor system can detect a precipitating event associated with a syncope onset, and acquire hemodynamic data in response to the detection of the precipitating event. A syncope analyzer circuit may generate temporal profiles of one or more hemodynamic parameters using the hemodynamic data. The syncope analyzer may use the temporal profiles to detect a syncopal event and to classify the syncopal event into one of a plurality of syncope categories. The detection and classification information may be output to a user or a process.

Abstract: The present invention discloses a surgical maneuvering system, in which movement of a moving element is used to control a surgical device such as a surgical tool or an endoscope. The moving element can be a tool or a portion of an operator's body. The relationship between the moving element and the surgical device can be any of: motion of a moving element controlling motion of a surgical device, motion of a moving element controlling an action of a surgical device, a command of a moving element controlling motion of a surgical device, or a command of a moving element controlling an action of the device. Commands are typically arbitrary movements such as shaking a tool. Actions are changes in a surgical device that do not change its overall position, such as closing a grasper.

Abstract: A computer Implemented method and system for detecting arrhythmias in cardiac activity are provided. The method is under control of one or more processors configured with specific executable instructions. The method obtains far field cardiac activity (CA) signals and applies a direction related responsiveness (DRR) filter to the CA signals to produce DRR filtered signals. The method compares a current sample from the CA signals to a prior sample from the DRR filtered signals to identify a direction characteristic of the CA signals and defines the DRR filter based on a timing constant that is set based on the direction characteristic identified. The method analyzes the CA signals in connection with the DRR filtered signals to identify a peak characteristic of the CA signals and determines peak to peak intervals between successive peak characteristic. The method detects at least one of noise or an arrhythmia based on the peak to peak intervals and records results of the detecting.

Abstract: A cochlear implant configured to be implanted within a patient may comprise an integrated circuit including a driver configured to generate a back telemetry signal encoded with information to be transmitted over a wireless communication link to a sound processor located external to the patient. The cochlear implant may also comprise a filter network that includes a first plurality of impedance components including a damping resistor, and a first and a second impedance component such as a capacitor or an inductor. The cochlear implant may also comprise an isolation network including a second plurality of impedance components configured to isolate, from the filter network and the driver, a forward telemetry signal received by the cochlear implant from the sound processor.

Abstract: Neuromodulation systems are described. An example neuromodulation system includes a controller wirelessly communicatively coupled to a host computer, a signal generator communicatively coupled to the controller, and a plurality of electrodes communicatively coupled to the signal generator. The controller, in conjunction with the signal generator and the at least one electrode are configured to deliver a stimulation to a mammal based on an instruction received from the host computer. The stimulation is configured to induce voluntary movement or restore function in the mammal.

Abstract: Systems and methods for selecting low-power, effective signal delivery parameters for an implanted pulse generator are disclosed. A representative system includes a signal generator and a computer-readable medium that, for first and second signals, increases and decreases an amplitude of the signal over multiple steps from a baseline amplitude at which the patient has a baseline response. At individual step increases and decreases, the system receives a pain score based on the patient's response. The instructions compare the pain scores for the two signals and determine one of the signals for additional therapy to the patient, based on the pain scores and an expected energy consumption of the signals.

Abstract: The invention generally relates to improved medical blood pump devices, systems, and methods. For example, blood pumps may be provided that include a housing defining a blood flow path between an inlet and an outlet. A rotor may be positioned in the blood flow path. A motor stator may be driven to rotate the rotor to provide the blood flow through the pump. Axial and/or tilt stabilization components may be provided to increase an axial and/or tilt stabilization of the rotor within the blood flow path. In some embodiments, biasing forces are provided that urge the rotor toward a bearing component. The biasing force may be provided by adjusting drive signals of the motor stator. Additionally, or alternatively, one or more magnets (e.g., permanent/stator magnets) may be provided to bias the rotor in the upstream and/or downstream direction (e.g., toward a bearing (chamfer, step, conical), or the like).

Abstract: Various systems and methods for implementing frequency domain adaptive motion cancellation filters. An example method includes receiving an optical signal representative of a physiological function. The example method further includes receiving a motion signal from an accelerometer. From the motion signal, a known motion spectrum is expressed as a sum of a product of coefficients for each component of the motion spectrum, wherein the coefficients are representative of the strength of the coupling between the motion signal and the optical signal. The example method may further include determining the coefficients of the motion spectrum using gradient descent and generating a decontaminated optical signal based on the optical signal and the motion model spectrum. Other systems, apparatuses, and methods are described.