Patents Examined by Anna R Falkowitz
  • Patent number: 11051958
    Abstract: A biodegradable in vivo supporting device is disclosed. In one embodiment, a coated stent device includes a biodegradable metal alloy scaffold made from a magnesium alloy, iron alloy, zinc alloy, or combination thereof, and the metal scaffold comprises a plurality of metal struts. The metal struts are at least partially covered with a biodegradable polymer coating. A method for making and a method for using a biodegradable in vivo supporting device are also disclosed.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: July 6, 2021
    Inventor: Eric K. Mangiardi
  • Patent number: 11052174
    Abstract: A non-tubular material for nerve regeneration induction, which can be used for the regeneration of a damaged part in a nerve, and which comprises: (A) a crosslinked form produced by crosslinking a low-endotoxin bioabsorbable polysaccharide having a carboxyl group in the molecule with at least one crosslinkable reagent selected from a compound represented by general formula (I) and a salt thereof via covalent bonds; and (B) a bioabsorbable polymer. R1HN—(CH2)n—NHR2 (I) [wherein R1 and R2 independently represent a hydrogen atom or a group represented by formula: —COCH(NH2)—(CH2)4—NH2, and n represents an integer of 2 to 18]. Thus, a medical material that can induce the regeneration of a damaged part in a nerve is provided.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: July 6, 2021
    Assignees: Mochida Pharmaceutical Co., Ltd.
    Inventors: Yoshihisa Suzuki, Masao Tanihara, Mitsuko Isaji
  • Patent number: 11033573
    Abstract: A non-ionic polymer coacervate is provided that is useful for forming adhesive bonds between wet surfaces, and that operates over a wide range of pH.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: June 15, 2021
    Assignee: The University of Akron
    Inventors: Abraham Joy, Amal Narayanan
  • Patent number: 11033479
    Abstract: The present invention provides an ?-gel forming composition and an ?-gel composition that uses an ?-gel formation composition that is highly stable and that does not become colored or deposit crystals, etc. over time. An ?-gel composition includes (A) 25-50 mass % of one or more higher aliphatic alcohol and/or higher fatty acid has 16 or more carbons, (B) 40-70 mass % of a specific polyoxyethylene sterol ether, and (C) 5-20 mass % of a specific polyoxyethylene dialkyl ester and/or ether. The ?-gel composition is generated by adding water.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: June 15, 2021
    Inventors: Reiji Miyahara, Tetsuro Yonezawa, Takashi Oka, Makoto Uyama, Saori Tanabe
  • Patent number: 11020511
    Abstract: A device includes a substrate and a hydrophilic polymer layer made of a hydrophilic polymer having a hydroxyl group. The hydrophilic polymer layer having a hydroxyl group is fixed to at least a part of a surface of the substrate and the hydrophilic polymer further has an amide group. A liquid film retention time of the device is 15 seconds or more. The device has a surface of a substrate which is hydrophilized. A method for producing the device by a simple method is also disclosed.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: June 1, 2021
    Inventors: Rumiko Kitagawa, Masataka Nakamura
  • Patent number: 11007278
    Abstract: Embodiments of the present disclosure provide for electroactive supramolecular polymeric assemblies, methods of making electroactive supramolecular polymeric assemblies, methods of using electroactive supramolecular polymeric assemblies, and the like.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: May 18, 2021
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: John Hardy, Christine E. Schmidt
  • Patent number: 10995177
    Abstract: Compositions and methods regarding guanidinium functionalized polycarbonates that provide potent antimicrobial activity against multidrug resistant (MDR) bacteria, including Klebsiella pneumoniae (K. pneumoniae) are provided. According to an embodiment, an antimicrobial guanidinium-functionalized polymer is provided that comprises a hydrophobic molecular backbone with cationic guanidinium moieties respectively bound to the hydrophobic molecular backbone via butyl spacer groups. The antimicrobial guanidinium-functionalized polymer self-assembles into a micelle structure with hydrophobic residuals of the antimicrobial guanidinium-functionalized polymer buried inside the micelle structure and the cationic guanidinium moieties exposed on an external surface of the micelle structure to target pathogens.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: May 4, 2021
    Inventors: James L. Hedrick, Yi Yan Yang, Chuan Yang
  • Patent number: 10994013
    Abstract: Provided is a dosage form for delivery of a therapeutic agent comprising a polymer matrix comprising arabinogalactan and a therapeutic agent uniformly dispersed in said polymer matrix. In some embodiments, the dosage form is selected from the group consisting of a microsphere, a nanosphere, a powder, a tablet, a film or a pellet enclosed in a capsule. Also provided are methods for preparing the dosage form.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: May 4, 2021
    Inventors: Kalpana N. Thakare, David B. Lebo
  • Patent number: 10987378
    Abstract: This invention relates to medicine, more specifically, to cardiac surgery, and may be used for protecting the heart from ischemia when administering cardioplegia in normothermia or hypothermia. The general-purpose cardioplegic solution contains pharmaceutically acceptable potassium ions; magnesium ions; a base and an acid providing a pH buffer in a range of 7.1-8.9; a diuretic providing osmolality in a range of 275-460 mOsmol/kg. Said solution is used for cardiac protection in cardiopulmonary bypass, as well as for achieving asystole and maintaining the achieved asystole. The procedure for administering the general-purpose cardioplegic solution involves maintaining the achieved asystole by decreasing the flow rate of starting components of said solution relative to the flow rate of autoblood thus decreasing the solution to autoblood ratio.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: April 27, 2021
    Inventor: Valentin Evgenevich Volgushev
  • Patent number: 10987300
    Abstract: Provided herein are long lasting hair compositions, color enhancers, and markers for selecting the same.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: April 27, 2021
    Assignee: Living Proof, Inc.
    Inventors: Soo-Young Kang, Zhaoxia Ji, Sara A. Turner, Ling-Fang Tseng, Dinara A. Villanueva, Eric G. Spengler
  • Patent number: 10973762
    Abstract: Provided is a polymeric micelle type DDS preparation that may efficiently exhibit pharmacological activity effects by enhancing migration characteristics, penetrability, and retention characteristics toward a diseased target tissue such as a tumor tissue or an inflammation-affected tissue, and thereby enhancing the action of a pharmacologically active substance. Disclosed is a block copolymer (A) having a hydrophilic polymer segment linked to a hydrophobic polymer segment, the hydrophilic polymer segment containing a polyethylene glycol chain, and the hydrophobic polymer segment containing a polyamino acid chain having a hydrophobic substituent in a side chain, wherein the hydrophilic polymer segment has a target binding site bonded thereto, and the main chain polymer combining the polyethylene glycol chain and the polyamino acid chain has a molecular weight of not less than 2 kilodaltons and not more than 10 kilodaltons.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: April 13, 2021
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Dai Kurihara, Tsuyoshi Fukuda, Yuki Kawano, Keiichirou Yamamoto
  • Patent number: 10945933
    Abstract: Provided are compositions suitable as hair styling compositions. Said compositions may comprise (a) at least one salt selected from the group consisting of sodium chloride, magnesium sulfate, calcium chloride, calcium phosphate and combinations thereof; and (b) at least one polyglyceryl ester having a structure represented by: wherein: R1 and R2 are each independently an alkenyl group having 9-21 carbon atoms and at least one unsaturated carbon-carbon bond, G is CH2—CH(OH)—CH2O, and n ranges from 1 to 15. Also provided are kits and methods of using said compositions.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: March 16, 2021
    Assignee: L'OREAL
    Inventors: Santiago Uribe, Aziza Suleiman, Anand Mahadeshwar, Vanessa Decarlo
  • Patent number: 10927210
    Abstract: The present invention relates to a composition comprising a polymeric elastomeric phase and an odoriferous active compound. In particular the present invention relates to a composition comprising a polymeric elastomeric phase and an odoriferous active compound and releasing said odoriferous active compound over a given period of time. The present invention concerns also objects comprising a polymeric elastomeric phase and an odoriferous active compound and releasing said odoriferous active compound over a given period of time.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: February 23, 2021
    Assignee: Arkema France
    Inventors: Jean-Marc Boutillier, Sylvain Bourrigaud
  • Patent number: 10905802
    Abstract: Embodiments of the invention include lubricious medical device coatings. In an embodiment the invention includes a coating for a medical device including a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; and a first cross-linking agent comprising at least two photoreactive groups; a second layer disposed on the first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; a second cross-linking agent comprising at least two photoreactive groups; and a polymer comprising polyacrylamide, the polymer derivatized with at least one photoreactive group. Other embodiments are included herein.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: February 2, 2021
    Assignee: Surmodics, Inc.
    Inventor: David E. Babcock
  • Patent number: 10898617
    Abstract: The disclosure concerns various medical devices implemented to provide a nitric oxide rich environment for anti-microbial or anti-thrombogenic benefits. The medical device generally includes a nitric oxide donor material that is contained within a sealed cavity, and a transport medium that defines and captivates the entirety of the cavity, wherein the transport medium is permeable to both water and nitric oxide. As the nitric oxide donor material becomes saturated with water from the surrounding tissue or fluids, nitric oxide is chemically released, and the resulting nitric oxide is communicated through the transport medium to a treatment site for anti-microbial and anti-thrombogenic benefits.
    Type: Grant
    Filed: January 21, 2018
    Date of Patent: January 26, 2021
    Assignee: BIOCREDE INC.
    Inventors: Hao Chen, Kevin Renehan, Kwun Yin Ho, Alexander Wolf
  • Patent number: 10898416
    Abstract: The invention relates to a composition, especially a cosmetic composition, including water, at least one film-forming agent, at least one volumizing agent, and an emulsification system comprising (i) about 2% to about 6% of low HLB emulsifier(s) (HLB value less than 8), (ii) about 2% to about 8% of intermediate HLB emulsifier(s) (HLB value of 8 to 16), and (iii) about 1% to about 8% of high HLB emulsifier(s) (HLB value greater than 16), with the compositions further including at least one colorant and/or excluding wax, as well as to methods of using such compositions.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: January 26, 2021
    Assignee: L'OREAL
    Inventors: Christine Marie Crane, Angeles Clara Fonolla-Moreno, Omotayo Awofesobi, Alice Monique Rosine Lefebvre
  • Patent number: 10889696
    Abstract: Microparticles that have a multimodal pore size distribution are provided, Notably, the pore structure of the present invention can be formed without the need for complex techniques and solvent chemistries traditionally employed to form porous microparticles. Instead, the microparticles contain a polymeric material that is formed from a thermoplastic composition, which is simply strained to a certain degree to achieve the desired porous network structure.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: January 12, 2021
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Vasily A. Topolkaraev, Neil T. Scholl, Ryan J. McEneany, Thomas A. Eby
  • Patent number: 10869841
    Abstract: Methods, systems, and devices are disclosed for encapsulating biological entities with preservation of their biological activity. In one aspect, a method of encapsulating a biological entity includes templating a biocompatible material onto a biological structure to form a coating structure enclosing the biological structure, the coating structure having a size in the nanometer range, in which the coated biological structure preserves its biological activity within the coating structure. In some implementations of the method, the biological structure includes a virus and the biocompatible material includes silica.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: December 22, 2020
    Assignee: The Regents of the University of California
    Inventors: Inanc Ortac, Gen Yong, Michael Benchimol, Sadik C. Esener
  • Patent number: 10864167
    Abstract: An improved process of making a benefit agent delivery particle and consumer products incorporating such particles are disclosed. The process comprises the steps of providing a first composition of water phase 1, water phase 2 and water phase 3. Water phase 1 comprises water and an initiator; water phase 2 comprises water, a water-soluble or dispersible amine(meth)acrylate or hydroxyl(meth)acrylate and a multifunctional (meth)acrylate. Water phase 3 comprises water, and carboxyalkyl(meth)acrylate and a base or quaternary ammonium acrylate. The first two water phases are combined to prereact the hydroxy- or amine(meth)acrylate and the multifunctional (meth)acrylate to form a multifunctional hydroxyl-amine(meth)acrylate pre-polymer.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: December 15, 2020
    Assignee: The Procter & Gamble Company
    Inventors: Hanwei Zhang, Todd Arlin Schwantes, Katie Ann Hobart, Diane Jean Williamson
  • Patent number: 10835481
    Abstract: Polymers comprising at least one cationic functional group and at least one ultraviolet light-absorbing compound are disclosed herein. The resulting polymers exhibit ultraviolet light-absorbing properties and may be used in sunscreen compositions for skin and/or hair.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: November 17, 2020
    Inventor: Amit Patel