Patents Examined by Anna R Falkowitz
  • Patent number: 11406658
    Abstract: The invention discloses a composition comprising glycyrrhizin, hyaluronic acid or a salt or a derivative thereof, and a viscosizing agent. The composition therefore finds advantageous application in all those cosmetic and therapeutic indications in which glycyrrhizin is used, since the composition according to the invention significantly improves the bioavailability thereof.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: August 9, 2022
    Assignee: ATG 20 S.R.L.
    Inventor: Marco Aldo Sanso′
  • Patent number: 11382845
    Abstract: Core-shell microcapsules comprising a hydrophobic core surrounded by a shell comprising a thermosetting resin comprising moieties derived from polyisocyanates, substantially unprotonated chitosan and another amine different from chitosan, characterized in that the substantially unprotonated chitosan is delivered in the solid, powder form to the locus of the encapsulation reaction. The core-shell microcapsules are provided in the form of a slurry comprising 10 to 50 wt % of microcapsules, based on the total weight of the slurry, and the shell of the microcapsules comprises from 0.1 to 20 wt % of moieties derived from chitosan, based on the total weight of the shell.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: July 12, 2022
    Assignee: GIVAUDAN SA
    Inventors: Nelly Bulgarelli, Ian Michael Harrison, Emmanuel Aussant
  • Patent number: 11369581
    Abstract: Described herein is a novel two-component composition including acetylsalicylic acid (ASA) and which is particularly useful in providing an aqueous solution of ASA for immediate peroral administration such as to treat imminent myocardial infarction in a person in need thereof.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: June 28, 2022
    Assignee: ASAMEDIC AS
    Inventor: John Bjorn Fredrikson
  • Patent number: 11370929
    Abstract: Provided is a bioink set for printing a construct that is able to carry cells, including a bioink which contains a biodegradable polyurethane and a biopolymer, and a divalent metal ion solution. The biopolymer is gelatin, agar, alginate salts, hyaluronic acid and salts thereof, chitosan, and any combination thereof. Also provided are a method of preparing a construct for carrying cells by three-dimensional printing with the bioink set, and a method of three-dimensional printing of cells by using an ink composition.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: June 28, 2022
    Inventors: Shan-hui Hsu, Cheng-Tien Hsieh
  • Patent number: 11344506
    Abstract: The present invention provides for an oral dissolvable film that includes a rapidly dissolving binder, a film forming polymer, a moisture deterring polymer, and at least one of a first active ingredient and a second active ingredient. Also provided is a method of forming an oral dissolvable film and kits that include the oral dissolvable film. Also provided is a method of delivering one or more active ingredients to a subject that include orally administering the oral dissolvable film.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: May 31, 2022
    Inventors: Jose Bernardo, Vered Gigi
  • Patent number: 11331639
    Abstract: The present invention relates to hydrogel beads having liquid crystalline structured phase. Process for preparing crystalline hydrogel beads is also an object of the invention. Perfuming compositions and consumer products comprising or consisting of said crystalline beads, in particular perfumed consumer products in the form of a personal care products or flavoured products, are also part of the invention.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: May 17, 2022
    Assignee: FIRMENICH SA
    Inventors: Vera Tchakalova, Laura Mesmin, Nathalie Thiebaut
  • Patent number: 11324835
    Abstract: A unit-type polyion complex for use in delivering nucleic acid to a target site in a patient includes one or more molecules of a block copolymer having a poly(ethylene glycol) segment and a cationic poly(amino acid) segment and one or more molecules of a nucleic acid. A total quantity of positive charges derived from side chains of the cationic poly(amino acid) segment of the block copolymer in the unit-type polyion complex is not offset by a total quantity of negative charges derived from the nucleic acid. Furthermore, the nucleic acid has a strand length of 10-50 bases, the molecular weight of the poly(ethylene glycol) segment is 40×103 or more, and the block copolymer has a binding constant (Ka) for the nucleic acid of 3.0×105 or more.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: May 10, 2022
    Inventors: Kazunori Kataoka, Kanjiro Miyata, Shigeto Fukushima, Kotaro Hayashi, Sumiyo Watanabe, HyunJin Kim, Kazuko Toh
  • Patent number: 11324826
    Abstract: Multifunctional compositions and methods are provided for therapeutic treatment of bacteria and cancers and for fluorescence diagnosis. Systems generate in situ reactive oxygen species such as singlet oxygen (1O2), hydroxyl radical (OH) and Juglone, and other chemotherapeutic agents. Methods provided selectively produce greater amounts of one reactive oxygen species over others. Variations are effective in aerobic, anaerobic or H2O2 rich environments and in presence of, or absence of, light. In H2O2 rich environment in absence of light, variations decompose H2O2 into O2 gas to remove excess H2O2 for elimination of hypoxic environment. Variations are formed of porphyrins, naphthalene derivatives, and metal ions, for illustration, free base tetrakis Ar substituted porphyrine core without metal or halide substitution but having hydroxyphenyl and alkyl pyridyl substituents at meso positions combined with dihydroxynaphthalene and +3 hydrated metal ions.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: May 10, 2022
    Inventor: Matibur Rahaman Zamadar
  • Patent number: 11318083
    Abstract: Compositions and methods for reshaping keratin-rich substrates while forming adherent flexible films contain emulsified or soluble mixtures of silanols and hemiaminals or the reaction products of silanols and hemiaminals including silylated hemiaminals. A method for treating split-ends in hair is also described.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: May 3, 2022
    Assignee: GELEST, INC.
    Inventors: Barry C. Arkles, Jonathan D. Goff, Alison Ane Phillips, Kerry Campbell Demella
  • Patent number: 11304357
    Abstract: The invention is directed to a seed coating composition containing a polymeric binder, a filler and a fibrous material. The seed coating composition can be formed by combining an aqueous composition pre-blend which contains a polymeric binder with a powder pre-blend which contains a filler and a fibrous material. The polymeric binder preferably contains polyvinylpyrrolidone, the filler preferably contains talc and the fibrous material preferably contains cellulose fibers.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: April 19, 2022
    Assignee: INCOTEC HOLDING B.V.
    Inventors: Tyler Alan Reece, Ryan Thomas Latham, Gerard Henry Denny
  • Patent number: 11278626
    Abstract: Aspects of the present disclosure include compositions having a plurality of individual polymeric nanowires. Individual polymeric nanowires according to embodiments include a bioactive compound. Methods for preparing and methods for administering the subject compositions of individual polymeric nanowires to a subject are also described. Kits having one or more components for practicing the subject methods are also provided.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: March 22, 2022
    Assignee: The Regents of the University of California
    Inventors: Colin R. Zamecnik, Tejal A. Desai
  • Patent number: 11266764
    Abstract: The invention relates to methods for producing a polymeric scaffold for use in tissue engineering applications or soft tissue surgery, as well as to the produced scaffolds and an associated kit. The method features a first fast drying step of applying a mechanical compression on a polymeric gel layer and a second slow drying step of the gel up to reach a polymer mass fraction of at least 60% w/w in the final scaffold. The method allows the production of scaffolds with high regeneration and healing properties of a grafted tissue via host cell invasion and colonization, and a good suturability. These goals are achieved through the formation within the scaffold of a non-uniform architecture creating softer and stiffer areas, which is maintained even upon re-swelling of the scaffold upon hydration of the final dried product.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: March 8, 2022
    Assignee: Regenosca SA
    Inventors: Peter Frey, Jeffrey A. Hubbell, Hans M. Larsson, Elif Vardar, Eva-Maria Balet, Ganesh Vythilingam, Kalitha Pinnagoda
  • Patent number: 11267965
    Abstract: Crosslinked biodegradable block polyurethane copolymers prepared from a plurality of biodegradable polymers or oligomers linked together via urethane bonds and crosslinked via a citrate ester are disclosed. Such copolymers can include folic acid and fabricated into medical devices such as a nerve growth conduit and locally deliver folic acid to a site of injury such as a PNS injury site.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: March 8, 2022
    Assignees: Aleo BME, Inc., The Penn State Research Foundation
    Inventors: Chao Liu, Jian Yang
  • Patent number: 11266678
    Abstract: The present invention relates to a composition for articular cavity injection comprising a nucleic acid and chitosan. More specifically, in the present invention, it was confirmed that the sol-gel transition occurred depending on the temperature in the composition for articular cavity injection prepared through the mixing of the nucleic acid and chitosan, the proteoglycan biosynthesis of the cartilage tissue was increased by the injection of the composition and the cartilage regeneration effect was exhibited, and the pain was alleviated and the walking speed and stride which are the joint motilities were improved. Therefore, development of a therapeutic agent for arthritis having an excellent therapeutic effect using the composition for articular cavity injection comprising the nucleic acid and chitosan of the present invention is expected.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: March 8, 2022
    Inventors: Ik Soo Kim, Han Gyu Kim, Su Yeon Lee
  • Patent number: 11246959
    Abstract: A biocompatible textile and methods for its use and fabrication are disclosed. The textile may be fabricated from electrospun fibers forming windings on a mandrel, in which the windings form openings having a mesh size between adjacent windings. The textile may also be fabricated by the addition of solvent-soluble particles incorporated into the textile while the windings are formed. Such particles may be removed by exposing the textile to a solvent, thereby dissolving them. Disclosed are also replacements for animal organs composed of material including at least one layer of an electrospun fiber textile having a mesh size. Such replacements for animal organs may include biocompatible textiles treated with a surface treatment process.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: February 15, 2022
    Inventor: Jed K. Johnson
  • Patent number: 11234441
    Abstract: The invention relates to the use of polyether modified short-chain siloxanes in agriculture in order to increase agronomic yield, a method for irrigation, and a kit containing at least one polyether modified short-chain siloxane, and an irrigation system.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: February 1, 2022
    Assignee: Evonik Operations GmbH
    Inventors: René Hänsel, Daniela Kruse, Ewald Sieverding, Carsten Riedl, Jordi Samso Ludwig
  • Patent number: 11230557
    Abstract: Novel rapamycin analogs and uses thereof are disclosed herein. The rapamycin analogs of the present disclosure show increased mTORC1 specificity and lowered mTORC2 specificity relative to rapamycin.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: January 25, 2022
    Assignee: Aeovian Pharmaceuticals, Inc.
    Inventors: Stelios T. Tzannis, Ian J. Massey, Alexandre Froidbise, Guillaume Eppe
  • Patent number: 11213476
    Abstract: The application describes a cosmetic method for the chemical treatment of keratinic fibers, in which i. a cosmetic composition is applied as a pretreatment agent to keratinic fibers, and ii. the keratinic fibers are subjected to a chemical treatment with an oxidizing agent and/or a reducing agent within a period of from about 5 seconds to about 24 hours after step i., wherein the cosmetic composition, based on its total weight, comprises from about 0.01 to about 4.00% by weight of a polyorganosiloxane of the formula (I) The damage to the keratinic fibers due to the oxidizing and/or reducing agents can be reduced by using the special pretreatment agent.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: January 4, 2022
    Assignee: HENKEL AG & CO. KGAA
    Inventor: Erik Schulze Zur Wiesche
  • Patent number: 11185441
    Abstract: The present disclosure provides an ophthalmic article. The ophthalmic article may comprise a biocompatible matrix comprising a copolymer derived from a caprolactone monomer and at least one other monomer. The ophthalmic article may also comprise an active agent or a diagnostic agent. The ophthalmic article may be configured to associate to a haptic of an intraocular lens (IOL).
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: November 30, 2021
    Assignee: LAYERBIO, INC.
    Inventor: Kenneth Jason Mandell
  • Patent number: 11166904
    Abstract: Disclosed are compositions, systems and methods for treating keratinous fibers such as hair. The compositions and systems comprise an oxazoline functionalized polymer and a carboxyl group-containing polymer. The compositions and methods are employed to improve the quality of the keratinous fibers.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: November 9, 2021
    Assignee: L'OREAL
    Inventors: Nghi Van Nguyen, Jim Singer, XianZhi Zhou, Jennifer Haghpanah, Charles Shaw