Abstract: A quantitative analysis film comprising a reagent layer comprising a cationic dye-forming color indicator for detecting hydrogen peroxide and an anionic polymer. By the use of such a color indicator and an anionic polymer in combination, a cationic dye is formed; the formed cationic dye is then bound and fixed to the anionic polymer to provide an intensified color. A method for the colorimetric assay of hydrogen peroxide or a precursor thereof with high sensitivity and high efficiency is also disclosed.

Abstract: A multizone element, for quantitative analyte determination in whole blood, containing a porous spreading zone separated from a reagent zone by a barrier zone, said barrier zone comprising a non-porous film comprising a polymer of: from 30 to 95 percent by weight of polymerized monomer having the structure ##STR1## from 0.25 to 30 percent by weight of polymerized monomer having the structure ##STR2## and from 0.1 to 50 percent by weight of polymerized monomer having the structure ##STR3## wherein: R.sup.1, R.sup.3, and R.sup.5 are independently selected from the group consisting of hydrogen and methyl,R.sup.2 is alkyl of from 1 to 16 carbon atoms,R.sup.4 and R.sup.6 are independently selected from the group consisting of alkylene groups having from 1 to 6 carbon atoms, ##STR4## wherein R.sup.7 is hydrogen, alkyl of 1 to 10 carbon atoms, or cycloalkyl of 5 to 10 carbon atoms, andM is NR.sup.8 R.sup.9 H.sup.+ X or SO.sub.3.sup.- X wherein R.sup.8 and R.sup.

Abstract: In a time-marking sedimentation process where two or more fractions in a sample containing liquid are to be separated entirely or partially by their specific weights in a tube or corresponding structure, a plug (2) of a hydrophilic plastic substance is brought into contact with the sample. The plug (2) has original dimensions smaller than the inner diameter of the tube (1) and has a specific weight lying between the specific weights of the fractions. The plug is adjusted with respect to its dimensions and/or substance so as to attain a swelling degree sufficient for the plug to jam in the tube (1), to mark the separation line between the fractions (3,4) after a certain predetermined period. Thereafter the position of the plug (2) in the tube is read. The method and device are particularly advantageous in medical connections, especially in the determination of the sedimentation reaction of blood, in which blood corpuscles are separated from plasma.

Abstract: A composition and process for permitting the separation of plasma or serum from whole blood. The composition includes glass fibers having an average diameter of from 0.2.mu. to 5.mu. and a density of 0.1 g/cm.sup.2 to 0.5 g/cm.sup.2. The process includes the steps of slowly trickling whole blood onto one side of a layer composed of the composition of glass fibers, whereby plasma or serum separated from the blood becomes available at another side of the layer. The total volume of the plasma or serum separated from the blood is limited to at most 50% of the absorption volume of the glass fiber layer.

Abstract: A testing piece for quantitative analysis of a substance in a body fluid, particularly in blood, said testing piece comprising an absorbent carrier containing in it reagents for measuring the substance and coated with a mixture of polymethylmethacrylate and polyvinyl formal. This testing piece enables the efficient and swift quantitative analysis of the substance in body fluid, especially in blood, in a short time without preliminary separating the serum from the blood.

Abstract: In an immunoassay procedure, an analyte in a solution is reacted with a reagent with a label. The reagent is segregated into solid phase (particles) and liquid phase (liquid) with the unreacted reagent ion one phase and the reacted reagent in another phase. An image of the suspension is then taken. The image is converted into electrical signal representation and is stored in digital form. The image is processed by locating and quantifying the labels. The distribution of the labels is representative of the distribution of the reagent between the particles and the liquid.

Abstract: Ambiguous measurement results can be obtained in the measurement and indication of high concentrations obtained in air of combustible gases when employing the thermal effect principle. In order to prevent such ambiguities from arising, the measuring range is, in accordance with the invention, limited to the linear part of the characteristic curve of the measuring sensor and displayed digitally.

Abstract: A method for preparing a sample for use in endotoxin test which comprises subjecting a sample of plasma or blood preparation to a contact with water-insoluble anti human .alpha..sub.2 -macroglobulin antibody and to a gel filtration by means of a gel of allyl dextran crosslinked with N,N'-methylenebis acrylamide or a gel of polyvinyl alcohol having many hydrophilic hydroxyl groups, and recovering the maximum molecular weight fraction.A kit for preparing a sample for use in the endotoxin test consisting of a set of a sample-developing column prepared by packing a water-insoluble anti-human .alpha..sub.2 -macroglobulin antibody and a gel of allyl dextran crosslinked with N,N'-methylenebis acrylamide or a gel of polyvinyl alcohol having many hydrophilic hydroxyl groups, both equilibrated with a buffer solution of pH 7.0-7.

Abstract: An analysis test strip and a process for the production of analysis test strips with a longitudinal carrier upon which is fixed at least one test field. The test field material is produced batchwise in an amount sufficient for a plurality of test strips, and thereafter, in a chronologically separate working step, is continuously fixed in the form of at least one band onto a parallel-running substantially wider band of test strip carrier material. The band as a whole is cut up transversely to its longitudinal direction into a plurality of test strips. Prior to the cutting up, a bar code is applied to the carrier band running parallel to the edges thereof of such high information density that it is suitable as a store of batch-specific information necessary for the quantitative evaluation of the reaction which has previously been obtained by investigation of the test field material of one batch.

Abstract: The present invention provides a process for the determination of the .beta.-lipoprotein fraction (LDL) in body fluids, especially in serum or plasma, wherein the LDL fraction is selectively precipitated from the sample by the addition of a polyvinyl sulphate with monovalent cations and then determined.The present invention also provides a reagent for the determination of the .beta.-lipoprotein fraction (LDL) in body fluids, especially in serum or plasma, wherein it contains polyvinyl sulphate.

Abstract: An improved test means, device and method for determining the ionic strength or specific gravity of an aqueous sample are disclosed. The test means comprises a weakly basic polyelectrolyte polymer salt and an indicator means capable of producing a detectable response to ion exchange between the polymer salt and the test sample. The polymer salt is one in which one or more of the basic moieties of the polymer is present as the salt of a strong organic acid.

Abstract: Method for the determination of lecithin concentration in crude oil. A sample of crude oil is admixed with a polar organic sample which does not dissolve lecithin, thus obtaining a suspension. The concentration of lecithin in the suspension is determined by the turbidimetric analysis, by measuring the transmitted light passed through the suspension. According to a preferred embodiment, a tungsten lamp provides the light to be transmitted through the suspension, the light passed being converted to Lux units by Luxmeter and expressed into concentration values of lecithin.

Abstract: Diverting apertures are operative to divert capillary transport of liquid from one transport zone into a second, unvented zone before the diverting aperture is surrounded by liquid flow in the first zone, by providing structure such that (a) the height of the head of liquid that is above the aperture, is selected to be sufficiently large, compared to the distance that the diverted liquid must flow into the second zone, and (b) the width of the first zone, and the dimension of the diverting aperture parallel thereto, have a predetermined relation.

Abstract: A plurality of cuvettes joined together by breakable links between each cuvette for use in testing blood for its ABO classification and the presence of a typical antibodies, and for crossmatching blood for compatibility, together with label means for indicating the reagents used in each cuvette and the identity of the person whose blood is being tested. The cuvettes may be adapted to accept a closure means which permits the cuvettes to be pre-packaged with reagents required to carry out blood tests. The cuvettes have a hydrophilic polymer coating thereon that is non-destructive of red blood cells.

Abstract: An indicator (10) for detecting contact with a naturally occurring polyhydroxyaromatic skin irritant or toxin like that found in poison ivy and the like comprises a carrier (12) treated with a reactant, such as ferric nitrate which reacts with the toxin and produces a distinct color change indicative of such contact.

Abstract: A method and apparatus which enables cell membrane dielectric breakdown to be determined. This determination is essential for the rapid inexpensive, reliable, in vitro quantification of lymphocyte tumor-cell cytotoxicity, lymphocyte membrane fluidity and the analysis of abnormal or tumor cells. The apparatus incorporates therein a cell dispenser used in conjunction with a DC electric field exposure tube. Electronic circuitry and its associated components process, acquire and store cell voltage signals as the cells are drawn through the electric field exposure tube. The procedure involves quantifying the breakdown voltage required to electrically collapse the cell membrane. The electrical collapse is termed a dielectric breakdown and is characterized by a reversible drop in the cell's resistivity.

Abstract: An abnormal condition detector detects an abnormal condition of an electric apparatus by sampling an insulating fluid filled in the electric apparatus under a pressurized condition and detecting a change of the condition of an indicator induced by an acidic gas in the sampled insulating fluid.

Abstract: A process and kit which are useful in determining whether the concentration of an aldehyde in a sample is in excess of a predetermined concentration. Two reaction systems are employed. The first reaction system acts first in transforming quantitatively to a first reaction product the amount of aldehyde equal to the predetermined concentration. The second reaction system then acts to transform any remaining aldehyde to a second reaction product which is detectable visually. In a preferred embodiment, delay in action of the second reaction system is achieved by formulating a reactant for the second reaction system in tablet form. Such tablets are also described herein.

Abstract: An improved method for analyzing inorganic oxy-anions by silylation with silylating agents of the formulae: ##STR1## wherein R is lower alkyl, Y is hydrogen, lower alkyl or perfluoroloweralkyl and Y.sub.1 is hydrogen or lower alkyl.

Abstract: In a silver stain method for protein in gels utilizing treatment with a reducing agent followed by treatment with a silver salt and actuating irradiation, the improvement comprising the use of a reducing agent consisting essentially of dithiothreitol in an amount effective to stain the protein but keep background staining to a minimum.