Patents Examined by Audrea Buckley
  • Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine
    Patent number: 9078923
    Abstract: The present invention relates to a stable fixed dose aqueous pharmaceutical composition (e.g., contained in a container) for nasal administration to a human, comprising mometasone or its salt, olopatadine or its salt. The composition may further include a hydrocolloid. The invention also relates to a process for preparing the pharmaceutical composition, and the use of the pharmaceutical composition in the treatment of rhinitis in a subject.
    Type: Grant
    Filed: September 11, 2014
    Date of Patent: July 14, 2015
    Assignee: GLENMARK PHARMACEUTICALS LIMITED
    Inventors: Ulhas Dhuppad, Ashok Katkurwar, Yashwant Gupta, Rajesh Ankam, Chandrakant Dhatrak
  • Multifunctional filler granule
    Patent number: 9078954
    Abstract: The invention relates to a filler granule comprising a matrix component (1), at least two base particles (2) that are at least mostly embedded in the matrix component, and a fibrous component (3). The fibrous component is attached to at least one of the base particles. The invention also relates to uses of these filler granules as well as to composite materials containing them.
    Type: Grant
    Filed: February 11, 2013
    Date of Patent: July 14, 2015
    Assignee: POBI CONCEPT OY
    Inventors: Mervi Puska, Allan Aho, Pekka Vallittu
  • Pharmaceutically acceptable solubilizing composition and pharmaceutical dosage form containing same
    Patent number: 9078921
    Abstract: A pharmaceutically acceptable solubilizing composition comprising (i) at least one tocopheryl compound having a polyalkylene glycol moiety and (ii) at least one alkylene glycol fatty acid monoester or mixture of alkylene glycol fatty acid mono- and diester is disclosed. The solubilizing composition is useful in the manufacture of a pharmaceutical dosage form which comprises a melt-processed mixture of at least one active ingredient, at least one pharmaceutically acceptable polymer. The active ingredient(s) may be inhibitors of HIV protease. The solubilizing composition enhances the bioavailability of the active ingredient after oral intake.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: July 14, 2015
    Assignee: Abbvie Deutschland GmbH & Co KG
    Inventors: Jörg Rosenberg, Jörg Breitenbach, Kennan Marsh, Bernd Liepold, Christoph Schmidt, Ute Lander
  • Compositions and methods for preventing cardiac arrhythmia
    Patent number: 9078882
    Abstract: Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: July 14, 2015
    Assignee: CORMATRIX CARDIOIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Compositions and methods for preventing cardiac arrhythmia
    Patent number: 9078873
    Abstract: Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: July 14, 2015
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Active substance combinations that have nematicidal, insecticidal, and fungicidal properties and are based on trifluorobutenyl compounds
    Patent number: 9072300
    Abstract: Disclosed are novel active substance combinations comprising specific heterocyclic trifluorobutenyls and previously known fungicidal agents. Said active substance combinations have a very good synergistic fungicidal, nematicidal, insecticidal, and/or acaricidal effect.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: July 7, 2015
    Assignee: ADAMA MAKHTESHIM LTD.
    Inventors: Wolfram Andersch, Ulrike Wachendorff-Neumann, Anton Kraus
  • Advanced functional biocompatible polymeric matrix containing nano-compartments
    Patent number: 9066885
    Abstract: The present invention provides a novel biomaterial which is a hybrid, self-assembling biopolymeric networked film that is functionalized through hydrophobic interactions with vesicles loaded with bioactive agents. The biomaterial compound is a polymeric network of hydrophobically modified chitosan scaffolds that is taken from solution and formed as a solid film. This solid state film is capable of hydrophobic interactions with the functionalized vesicles. The vesicles include one or more lamellar structures forming one or more nano-compartments that are capable of containing similar or alternative active moieties within. Use of the film results in a degradation of the chitosan scaffold thereby releasing the active moieties within the vesicles from the scaffold. Application of the current invention occurs through various delivery mechanisms and routes of administration as will be described herein.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: June 30, 2015
    Assignee: University of Maryland, College Park
    Inventors: Srinivasa R. Raghavan, Gregory F. Payne, Chao Zhu, Matthew B. Dowling
  • Compositions for preventing cardiac arrhythmia
    Patent number: 9060969
    Abstract: Disclosed herein are compositions and methods for treating or preventing a cardiac arrhythmia in a subject.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: June 23, 2015
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Transdermal nicotine salt delivery system
    Patent number: 9056061
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: June 16, 2015
    Assignee: ALZA Corporation
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J. N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Vaginal lubricant comprising hyaluronic acid
    Patent number: 9044387
    Abstract: A vaginal lubricant comprising high molecular weight hyaluronic acid combined with low molecular weight hyaluronic acid and/or chitosan which has improved stability and which has applications in, for example, maintaining and/or promoting sperm motility.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: June 2, 2015
    Assignee: British Biocell International Limited
    Inventors: Xiaobin Zhao, Kevin Alexander Burd
  • Compositions containing a micronized wax
    Patent number: 9040027
    Abstract: The invention relates to a composition comprising at least one oil-dispersible micronized wax which, if desired, can be processed at room temperature.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: May 26, 2015
    Assignee: L'Oréal
    Inventors: Hy Si Bui, Anita Chon Tong, Susan Halpern, Mohamed Kanji, Fatima Ramadan, Yoriko Kawaratani, Nishith Patel, Ram Hariharan
  • Metal-enhanced fluorescence nanoparticles
    Patent number: 9023372
    Abstract: The present invention relates to nanoparticles comprising a metallic core with a surface coating, wherein the coating comprises at least an excitable radiative molecule attached thereto or impregnated therein, and wherein the excitable molecule is positioned at a sufficient distance from metallic core to enhance emissions when excited. The nanoparticles are included in compositions that may be used for surface coatings, cosmetics, assays, flow velocity measurements and targeting of tissue.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: May 5, 2015
    Assignee: University of Maryland
    Inventor: Chris D. Geddes
  • Hair follicle graft from tissue engineered skin
    Patent number: 9023380
    Abstract: The present invention provides a hair graft comprising (a) tissue engineered skin comprising a tissue engineered epidermal layer, a tissue engineered dermal layer, and hair follicle progenitor cells and (b) a scaffold. The invention also provides methods of making and using the hair grafts of the present invention.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: May 5, 2015
    Assignee: Aderans Research Institute, Inc.
    Inventors: Thomas H. Barrows, Preeti MacIntyre, Kenneth Justin Washenik
  • Functionalized calcium phosphate hybrid systems for the remineralization of teeth and a method for producing the same
    Patent number: 9023373
    Abstract: A dental remineralizing system, including a functionalized calcium-containing complex having an organic surfactant component mechanochemically attached to a distressed calcium phosphate component and blended with the comestible material.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: May 5, 2015
    Assignee: Indiana Nanotech
    Inventor: Robert L. Karlinsey
  • Intumescent fire retardant paint with insecticide
    Patent number: 9005642
    Abstract: Intumescent fire retardant paint includes an insecticide. The paint can be a latex. Another active agent, for example, a mold inhibitor, may be included. The insecticide may be, for example, a termiticide.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: April 14, 2015
    Assignee: No-Burn Investments, L.L.C.
    Inventors: Michael John Mabey, William Kish
  • Oral preparation with controlled release
    Patent number: 9005658
    Abstract: A pharmaceutical pellet is provided, comprising a spherical core containing the active substance with a smooth surface and a coating on the core, which controls pH-independent release of the active substance. With a pellet of this kind, the release of the active substance may follow a profile with a lag-phase from 60 minutes to 840 minutes, where during the lag-phase a proportion of 5 wt. % or less of the active substance is released. Furthermore, the active substance may be released from the pellet with a profile such that, after the lag-phase, the release of the active substance is between 3 and 25 wt. % per hour. The active substance is a metoprolol salt.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: April 14, 2015
    Assignee: ADD Advanced Drug Delivery Technologies Ltd.
    Inventors: Burkhard Schlutermann, Manfred Kohlmeyer
  • Ultrasonic cancer treatment enhancer and cell killer
    Patent number: 8992958
    Abstract: There is provided an ultrasonic cancer treatment enhancer and cell killer that can significantly improve the effect of treating cancer by ultrasonic irradiation while ensuring a high level of safety. The ultrasonic cancer treatment enhancer and cell killer comprise metal semiconductor particles and can be activated upon ultrasonic irradiation to kill or destruct cancer cells.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: March 31, 2015
    Assignee: Toto Ltd.
    Inventors: Koki Kanehira, Shuji Sonezaki, Yumi Ogami, Toshiaki Banzai
  • Process for producing (3S)-1-menthyl 3-hydroxybutyrate and sensate composition
    Patent number: 8986660
    Abstract: Disclosed is a cooling component or sensate component which does not have undesirable stimulus feeling, bitterness and the like and is excellent in the persistence of refresh-feeling and cool-feeling, a sensate composition which comprises the same, and various products that comprise said sensate composition.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: March 24, 2015
    Assignee: Takasago International Corporation
    Inventors: Kazuma Hojo, Takashi Aida, Kenya Ishida
  • Compositions and methods for preventing cardiac arrhythmia
    Patent number: 8980296
    Abstract: Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: March 17, 2015
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventors: Robert G. Matheny, Beecher C. Lewis
  • Cosmetic composition containing retinol stabilized by porous polymer beads and nanoemulsion
    Patent number: 8980293
    Abstract: The present invention relates to a method for stabilizing retinol (Vitamin A), an unstable fat-soluble material, to use the same in cosmetics. The present invention provides an anti-inflammatory and skin wrinkle reducing cosmetic composition containing retinol stabilized by nano-emulsification, wherein a retinol polymer nanocapsule formed by capturing retinol with porous polymer particles is nano-emulsified by a mung bean MCT (medium chain triglyceride) extract and lecithin for stabilizing retinol.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: March 17, 2015
    Assignee: Act Co., Ltd.
    Inventors: Sang-Ho Jeong, Ji-Hyun Son, Su-Jin Jang, Yun-Jeong Kim, Jong-Woo Cheon