Abstract: An imaging system and method acquires non-contrast images of a region of interest in a body and determines an entrance criterion based on the non-contrast images. The entrance criterion dictates conditions in which to begin acquiring contrast imaging exposures of the region of interest. An amount of a contrast agent is measured in one or more locations in the imaged body subsequent to acquiring the non-contrast images. The system and method determine that the one or more conditions of the entrance criterion are met based on the amount of the contrast agent that is measured in the imaged body, and acquire one or more contrast images of the region of interest in the imaged body responsive to determining that the one or more conditions of the entrance criterion are met.

Abstract: Physiological parameter detecting apparatuses and methods of detecting the physiological parameters are provided. A physiological parameter detecting apparatus includes: a light source configured to emit a light onto a region of an object; an optical path converter configured to receive the light returning from the object and convert an optical path of the received light; an optical detector configured to detect the light that has the converted optical path; and a controller configured to extract physiological information of the object from the detected light.

Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.

Abstract: A diagnosis assistance device includes a control unit that generates line data indicating an intensity value of a reflected wave from an object, which is present in a transmission direction of ultrasound, for each combination of a movement position of an ultrasound transducer that radially transmits the ultrasound while being moved inside a biological tissue and the transmission direction of the ultrasound with reference to an observation result of a cross section of the biological tissue by the ultrasound transducer and generates a detection image which includes pixels corresponding to the generated line data and in which pixels corresponding to the line data at the same movement position are arranged in one direction. Pixels corresponding to the line data in the same transmission direction are arranged in a direction perpendicular to the one direction, and each pixel value is set according to an abnormality degree of the generated line data.

Abstract: In an ultrasound diagnostic system, in a case where a routine test in which a plurality of parts of a subject are sequentially subjected to ultrasound diagnosis in accordance with a determined procedure is performed and in a case where information on the subject is input from an input unit, a workstation-side control unit makes a workstation-side display unit perform a second display in which one past image and a current image including an ultrasound image newly created in an ultrasound diagnostic device with respect to a part corresponding to the one past image are displayed side by side on a past image region and a current image region adjacent to each other, in an arrangement order of a plurality of past images in a past routine test of the subject stored in the storage unit.

Abstract: A system and method of monitoring a procedure includes a medical device. The medical device includes an elongate device including a flexible body, a tracking system disposed along at least a portion of the flexible body, and one or more processors communicatively coupled to the tracking system. The one or more processors are configured to receive a route to a target location in an anatomy, determine one or more features of the route based on a first anatomical representation, generate a reduced anatomical representation based on the one or more features of the route, receive real-time position information from the tracking system, associate the real-time position information to the reduced anatomical representation, and dynamically display the reduced anatomical representation with the associated real-time position information.

Abstract: A method of performing magnetic resonance imaging of a body includes a) immerging the body in a static and substantially uniform magnetic field; b) exciting nuclear spins inside the body using at least one radio-frequency pulse; c) applying to the body a time-varying magnetic field gradient defining at least one trajectory (ST) in k-space and simultaneously acquiring samples of a magnetic resonance signal so as to perform a pseudo-random sampling (KS) of the k-space; and d) applying a sparsity-promoting nonlinear reconstruction algorithm for reconstructing a magnetic resonance image of the body; wherein, at least in a low-spatial frequency region of the k-space, the distance between any two adjacent points belonging to a same trajectory is lower than 1/FOV, FOV being the size of a field of view of the reconstructed image. A magnetic resonance imaging apparatus for carrying out such a method is also provided.

Abstract: A hydrogel sensor device can include a crosslinked hydrogel body which changes in volume in response to an environmental stimulus, a support post positioned to mechanically support the crosslinked hydrogel body during the change in volume, and a sensor positioned to detect the change in volume in the crosslinked hydrogel body.

Abstract: Apparatus for operating MRI is disclosed. The apparatus comprises: a control for operating an MRI scanner to carry out an MRI scan; an input for receiving first and second MRI scans respectively at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from the first and the second MRI scans by analyzing the scans to distinguish between a population in which contrast clearance from the tissue is slower than contrast accumulation, and a population in which clearance is faster than accumulation; and an output to provide an indication of distribution of the populations. The control is configured to carry out the first scan at least five minutes and no more than twenty minutes post contrast administration and to carry out the second scan such that the predetermined time period is at least twenty minutes.

Abstract: Shape-sensing systems and methods for medical devices. The shape-sensing system can include a medical device, an optical interrogator, a console, and a display screen. The medical device can include an integrated optical-fiber stylet having fiber Bragg grating (“FBG”) sensors along at least a distal-end portion thereof. The optical interrogator can be configured to send input optical signals into the optical-fiber stylet and receive FBG sensor-reflected optical signals therefrom. The console can be configured to convert the reflected optical signals into plottable data for displaying plots thereof on the display screen. The plots can include a plot of curvature vs. time for each FBG sensor of a selection of the FBG sensors in the distal-end portion of the optical-fiber stylet for identifying a distinctive change in strain of the optical-fiber stylet as a tip of the medical device is advanced into a superior vena cava of a patient.

Abstract: Described herein are embodiments of an approach to diagnosing pancreatic cystic lesions using light scattering spectroscopy. In some embodiments, the approach includes an apparatus including a spatial gating probe to isolate light reflected by the epithelial tissue of the internal cyst surface using spatial gating. In some further embodiments, the apparatus includes a scanning fiber probe that is capable of rotational and linear motion in order to scan the entire internal surface of the cyst. Use of such an approach may be advantageous to improve the accuracy of diagnosing pancreatic cystic lesions as cancerous, precancerous, or benign.

Abstract: The present disclosure describes a fast-scanning optical-resolution photoacoustic (fsOR-PAE) endoscope for imaging vasculature within tissues in vivo that includes an ultrasonic transducer and a scanning mirror within a lumen of an elongate casing. The scanning mirror is configured to direct the laser pulses from the pulsed laser source to a focal spot outside the casing in a scanning pattern via an imaging window formed in the casing. The scanning mirror is further configured to direct a plurality of photoacoustic signals from the focal spot to the ultrasonic transducer via the imaging window.

Abstract: An insert having a photoacoustic wave generation portion, an acoustic wave detection unit that detects photoacoustic waves and reflected acoustic waves, an acoustic image generation unit that generates a B mode acoustic image on the basis of the reflected acoustic waves, a photoacoustic image generation unit that generates a photoacoustic image on the basis of the photoacoustic waves, an image output unit that outputs a display image obtained by synthesizing the B mode acoustic image and the photoacoustic image, and a control unit that controls a detection frequency of the photoacoustic waves used in a case where the photoacoustic image is generated in the photoacoustic image generation unit on the basis of a resolution of the B mode acoustic image forming the display image are included.

Abstract: An ultrasound diagnostic apparatus including a hardware processor that: calculates a plurality of eigenvectors by performing principal component analysis on a time-series reflection wave data group; calculates a principal frequency component of a time direction represented by the plurality of eigenvectors; determines a reduction rate of each of the plurality of eigenvectors on a basis of the principal frequency component of each of the plurality of eigenvectors and a clutter component reduction condition that defines a reference frequency for reduction of a clutter component; calculates a filter coefficient for reduction of the clutter component on a basis of the plurality of eigenvectors, and the reduction rate corresponding to each of the plurality of eigenvectors; and generates blood flow image data by applying the filter coefficient to the time-series reflection wave data group.

Abstract: An ultrasound (US) system (10) includes a US scanner (14) and a US probe (12) operatively connected to the US scanner.

Abstract: Catheter systems of the invention involve guided and informed dissolution of occlusions in blood vessels. According to certain aspects, a catheter system of the invention includes an elongate body defining a first lumen and comprising a distal portion, an inner member configured for insertion into the first lumen, the inner member comprising an energy source configured to deliver therapeutic energy to a treatment site, and an imaging assembly located at the distal portion of the elongate body. In some embodiments, the catheter system includes a functional flow sensor in addition to or as an alternative to the imaging assembly.

Abstract: Apparatus for operating MRI is disclosed. The apparatus comprises: a control for operating an MRI scanner to carry out an MRI scan; an input for receiving first and second MRI scans respectively at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from the first and the second MRI scans by analyzing the scans to distinguish between a population in which contrast clearance from the tissue is slower than contrast accumulation, and a population in which clearance is faster than accumulation; and an output to provide an indication of distribution of the populations. The control is configured to carry out the first scan at least five minutes and no more than twenty minutes post contrast administration and to carry out the second scan such that the predetermined time period is at least twenty minutes.

Abstract: A computer implemented method comprises receiving a model of a tissue region, steering a distal end of a catheter within a body to a first area of a tissue region, and obtaining a first image from the distal end of the catheter of the first area of the tissue region. The method further comprises mapping the first image of the first area of the tissue region to the model of the tissue region and displaying the first image of the first area of the tissue region on the model of the tissue region.

Abstract: An electromagnetic shockwave transducer includes a double-faced coil of wire wound around an insulator. The coil has a first coil face on one side of the insulator and a second coil face on an opposite side of the insulator. Coil ends of the coil are electrically coupled to a current source, which produces a current pulse in the coil so as to produce a force between the coil faces.

Abstract: A method and processing system for providing a three-dimensional, 3D, ultrasound image along with an additional ultrasound acquisition. A location of the additional ultrasound acquisition with respect to the three-dimensional ultrasound image is determined or obtained. After obtaining the 3D ultrasound image and the additional ultrasound acquisition, initial display data is for display of only the 3D ultrasound image. In response to a user input, second display data is generated for displaying both the 3D ultrasound image and the additional ultrasound acquisition. The display of the additional ultrasound acquisition is based on the location of the additional ultrasound acquisition with respect to the three-dimensional ultrasound image.