Abstract: A method for facilitating a Parkinson's Disease (“PD”) assessment of a patient includes capturing first video of a patient performing first test movements while holding the mobile device; capturing second video of the patient performing second test movements while maintaining the mobile device on their person; capturing third video of the patient performing third test movements including standing and walking; capturing one or more IMU readings using an IMU of the mobile device; processing the first video, the second video, and the third video according to (i) a hand landmark model to generate one or more hand biomarkers, (ii) a face landmark model to generate one or more face biomarkers, and (iii) a body landmark model to generate one or more body biomarkers; and determining an assessment score based on a standardized PD assessment by processing the biomarkers.

Abstract: An endovascular interventional method is provided that includes the steps of: inserting a catheter into a target blood vessel, wherein the catheter is coupled to a system that provides a continuous delivery of contrast and of a hyperosmotic fluid supply; injecting the contrast and determining a rate of flow that achieves angiographic filling of the target blood vessel at a first time; injecting the hyperosmotic fluid continuously at the rate of flow that achieves angiographic filling at the first time for a first period of time; injecting the contrast and determining a rate of flow that achieves angiographic filling of the target blood vessel at a second time following the first period of time; and injecting the hyperosmotic fluid continuously at the rate of flow that achieves angiographic filling at the second time for a second period of time.

Abstract: Kinetic monitoring of in vivo metabolism of labelled tracers is based on singular value decomposition or Tucker Decomposition of magnetic resonance spectral image data. Data decomposition is used in conjunction with rank reduction to improve signal-to-noise ratio. Rank reduction can be applied in one or more of a spectral, spatial, or temporal dimension. Rank is generally reduced based on a number of expected analytes/metabolites or fit of measured data to a model.

Abstract: Systems and methods are disclosed that provide for regular, periodic or continuous monitoring of fluid volume based on direct measurement of an inferior vena cava (IVC) physical dimension using a wireless measurement sensor implanted in the IVC. By basing diagnostic decisions and treatments on changes in an IVC physical dimension, information on patient fluid state is available across the entire euvolemic range of fluid states, thus providing earlier warning of hypervolemia or hypovolemia and enabling the modulation of patient treatments to permit more stable long-term fluid management.

Abstract: A catheter, comprising: a drive cable having cylindrical opening extending from a proximal end to a distal end along a longitudinal axis thereof; an imaging probe having an optical fiber arranged inside the drive cable and a distal optics assembly fixedly attached to the drive cable at the distal end thereof; a first radiopaque marker arranged at a distal end of the drive cable at a position distal and parallel to the distal optics assembly; and a second radiopaque marker arranged at a predetermined distance from the distal end of the drive cable at a position proximal to the distal optics assembly. The second radiopaque marker is arranged concentric or coaxially to the longitudinal axis in a space between the longitudinal axis and an outer surface of the drive cable.

Abstract: An ultrasonic diagnostic apparatus of an embodiment includes an ultrasonic probe and processing circuitry. The ultrasonic probe repeatedly performs scanning in which a plane wave or a diffused wave is continuously transmitted a plurality of times in the same direction in a plurality of directions. The processing circuitry performs processing of applying a moving target indicator (MTI) filter to an unequal interval data sequence in the same direction obtained by the scanning and extracting a blood flow signal in each of the plurality of directions, performs processing of generating an autocorrelation signal by performing an autocorrelation operation on a plurality of blood flow signals in the same direction for each of the directions, and estimates a velocity value of blood flow on the basis of a complex signal generated by performing complex addition of a plurality of autocorrelation signals generated for the plurality of directions.

Abstract: A wearable Doppler blood flowmeter can be used with an inflatable cuff to measure blood flow, such as for assessing peripheral artery disease (PAD). The present approach can include techniques such as providing or using a wearable acoustic Doppler blood flowmeter, without requiring the intricate manipulation of a handheld Doppler probe. The system can select a pair of acoustic transmitter and acoustic receiver from a set of more than two transducers, including one or more of different locations, orientations, or spacings, such as to vary a targeted region. The RF echo response signal can be translated to an audio response signal. An audio response signal injection circuit can adaptively inject a noise or other enhancement signal, such as to help improve perceptibility of an audible characteristic of pulsatile arterial blood flow. A trained machine learning model can be employed to select or adjust operating settings, to assess diagnostic information, or both.

Abstract: Devices, systems, and methods obtain first imaging data and first timestamps that correspond to the first imaging data; obtain second imaging data and second timestamps that correspond to the second imaging data; demodulate the first imaging data to acquire a first timing signal; demodulate the second imaging data to acquire a second timing signal; and calculate a delay value based on the first timing signal, the second timing signal, the first timestamps, and the second timestamps.

Abstract: A method for automatic multi-object localization and/or vital sign monitoring is provided. The method comprises the steps of receiving a radar signal in order to form a corresponding observation matrix, reducing noise by applying singular value decomposition to the observation matrix, processing the result of the singular value decomposition by an independent component analysis in order to estimate the corresponding sources, and estimating propagation channels of the estimated sources by minimizing the corresponding residual error based on the observation matrix and the estimated sources.

Abstract: An endoscopic capsule system comprising: an endoscopic capsule having magnetic characteristics; an extracorporeal guiding and moving apparatus having a moveable multi-hinged cantilever arm which is pivotably mounted at a support stand at one end and at an effector having magnetic characteristics at the other end to move the endoscopic capsule in accordance with movement of the effector; a controller device to define the position and orientation of the endoscopic capsule relative to the effector, and a force and/or moment generation device or a braking device to generate counter forces and/or counter moments or braking forces against moving and/or guiding forces that are manually applied to the cantilever arm and/or effector in accordance with the actually defined position and/or orientation of the endoscopic capsule relative to the effector.

Abstract: A positioning imaging device images the subject facing a radiation detection unit to obtain a positioning image of the subject. An imaging menu selection unit selects an imaging menu corresponding to the positioning image from one or a plurality of imaging menus registered in advance in an imaging menu registration memory. A system control unit performs imaging control on a radiation source or the radiation detection unit according to the imaging menu selected by the imaging menu selection unit.

Abstract: A system and method for personalized diagnosis of human body surface conditions from images acquired from a mobile camera device. In an embodiment, the system and method is used to diagnose skin, throat and ear conditions from photographs. A system and method are provided for data acquisition based on visual target overlays that minimize image variability due to camera pose at locations of interest over the body surface, including a method for selecting a key image frame from an acquired input video. The method and apparatus may involve the use of a processor circuit, for example an application server, for automatically updating a visual map of the human body with image data. A hierarchical classification system is proposed based on generic deep convolution neural network (CNN) classifiers that are trained to predict primary and secondary diagnoses from labelled training images.

Abstract: An ultrasound transducer unit (12), e.g. probe, is configured with a friction guiding function. The transducer unit (12) comprises a vibration generating means (20) at a tissue contact area, and has means for sensing a sliding direction of the transducer unit across a tissue surface (42) at which the contact area is incident. The tissue surface may be an external skin surface or an internal tissue surface, e.g. in case of a catheter. A control means is operable to control the vibration of the vibration generator to adjust a level of friction at the tissue contact area. This is used by the control means to implement a friction guiding function for guiding a user in sliding the unit across the incident surface, e.g. toward a target location (44), based on controlling the friction level responsive to sensed sliding direction, for instance providing lower friction when sliding is in a target direction, while leaving other directions with relative higher frictional resistance.

Abstract: Systems, devices, and methods for displaying multiple intraluminal images in a luminal assessment are provided. An intraluminal imaging device is provided which is configured to be positioned within a body lumen of a patient and receive imaging data associated with the body lumen. The intraluminal imaging device may be in communication with a controller configured to display two or more transverse images of the body lumen on a single display device. The system may also be configured to automatically measure, display, and compare measurements of features, including misalignment or malapposition of a stent, the diameter and area of the stent at various locations along the stent, as well as the diameter and area of the lumen before the stent is positioned.

Abstract: A system for magnetic field direction detection when placing a catheter is disclosed, including a sensor configured to track a medical device, the sensor including a magnetic sensor printed circuit board including a plurality of magnetometers arranged in a magnetometer array. The system can include a console coupled to the sensor, including a processor and non-transitory computer-readable medium having stored a plurality of logic modules that when executed by the processor, are configured to perform operations including receiving detected magnetic field strength values detected by the plurality of magnetometers, determining a position on the sensor of each of the plurality of magnetometers, determining the magnetic field source direction based on the detected magnetic field strength values and the position on the sensor of each of the plurality of magnetometers, and displaying the magnetic field source direction on the display.

Abstract: A facility for automatically establishing measurement location controls for Doppler ultrasound studies is described. The facility receives a first ultrasound image, and user input selecting an anatomical structure appearing in it. The facility performs localization to determine the location of the selected anatomical structure in the initial image, and determines a first placement of measurement location controls relative to the structure. On the ultrasound machine, the facility invokes one or more first Doppler ultrasound modes using the first placement. The facility receives a second ultrasound image produced by the ultrasound machine using the one or more first modes; determines a flow location and direction based on the second ultrasound image; and determines a second placement relative to the flow location. The facility invokes one or more second Doppler ultrasound modes using the second placement, and receives results from the invocation of the one or more second Doppler ultrasound modes.

Abstract: The present invention, in some embodiments thereof, relates to methods and/or apparatus for measuring the effectiveness of a renal denervation treatment. In some embodiments, a method for determining effectiveness of the denervation treatment comprises tracking at least one of arterial wall movement, arterial blood flow rate, arterial blood flow velocity, blood pressure and arterial diameter at one or more selected locations in the renal artery over time, and assessing the effectiveness of said renal denervation treatment according to results obtained by tracking.

Abstract: Imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to imaging a region of interest in tissue with photoacoustic and ultrasound modalities. In some embodiments, a medical sensing system includes one or more external optical emitters and a measurement apparatus configured to be placed within a vascular pathway. The one or more optical emitters and the measurement apparatus may be moved together synchronously. The measurement apparatus may be configured to receive sound waves created by the interaction between emitted optical pulses and tissue, and transmit and receive ultrasound signals. The medical sensing system may also include a processing engine operable to produce images of the region of interest and a display configured to visually display the image of the region of interest.

Abstract: A method of aligning an imaging device in connection with robotic surgery includes causing a robot to position a reference target over a body of a patient; receiving image data from an imaging device; identifying, with an image processing algorithm, at least a first portion of an anatomical element in the image data; identifying, with a target detection algorithm, at least a first portion of a reference target in the image data; comparing a determined location of the imaging device, the reference target, and the anatomical element to yield a location determination and causing at least one of the robot to re-position the reference target or the imaging device to re-position.

Abstract: A surgical image acquisition system includes multiple illumination sources, each source emitting light at a specified wavelength, a light sensor to receive light reflected from a tissue sample illuminated by each of the illumination sources, and a computing system. The computing system may receive data from the light sensor when the tissue sample is illuminated by the illumination sources, and calculate structural data related to one or more characteristics of a structure within the tissue. The structural data may be a surface characteristic such as a surface roughness or a structure composition such as a collagen and elastin composition. The computer system may further transmit the structural data to a smart surgical device. The smart devices may include a smart stapler, a smart RF sealing device, or a smart ultrasonic cutting device. The system may include a controller and computer enabled instructions to accomplish the above.