Abstract: An apparatus and system for treating a wound having a cavity is disclosed. The apparatus comprises a scaffold including a scaffold lamina and a tissue lamina wherein the scaffold lamina forms a laminate in fluid communication with the tissue lamina. The laminate is rolled into a generally cylindrical shape having two end surfaces. The apparatus further comprises a manifold having a port for coupling to a source of reduced pressure and that is positioned in fluid communication with the scaffold to provide reduced pressure to the scaffold lamina and the wound. The apparatus also comprises a drape formed of substantially impermeable material to cover the scaffold and the manifold within the wound.

Abstract: A system for dialysis is disclosed. The system uses renal failure therapy fluid, such as dialysis fluid, several times before it is discarded. In a home hemodialysis application, the patient's blood is passed through the dialyzer several times, that is, multiple passes through the dialyzer, until the dialysis fluid is saturated or near saturation, with waste products from the patient's blood. In peritoneal dialysis, the dialysate is used at least twice within the patient's peritoneal cavity, i.e., multiple passes, before it is discarded. This has the effect minimizing the amount of dialysate a patient must handle and dispose of in the dialysis process.

Abstract: An absorbent article to be worn by a wearer having a skin-contacting sheet such as a topsheet, a backsheet, an absorbent core and a colored hydrophilic lotion, that not only helps to reduce the adherence of the menses or feces to the skin, thereby improving the ease of menses or bowl movement (BM) clean up, but that also may serve as a wetness indicator. The absorbent articles may be infant (baby) diapers, including training pants, adult incontinence articles and the like.

Abstract: Target tissue may be removed from a subject using a cannula that has an interior cavity and an orifice configured to permit material to enter the cavity. This is accomplished by generating a negative pressure in the cavity so that a portion of the tissue is drawn into the orifice. Fluid is then delivered, via a conduit, so that the fluid exits the conduit within the cavity and impinges against the portion of the tissue that was drawn into the orifice. The fluid is delivered at a pressure and temperature that causes the tissue to soften, liquefy, or gellify. The tissue that has been softened, liquefied, or gellified is then suctioned away.

Abstract: Thus, systems and methods for a debriding wound vacuum may include a sponge for application to a wound, a flexible sheet for covering and sealing the wound, and a bladder. The bladder may be in fluid communication with at least a portion of the sponge. The bladder preferably contains a debridement substance. A negative pressure device may form part of the system and may be used to apply negative pressure via a hollow tube to the sponge. The negative pressure device may be adapted to apply negative pressure to the sponge via the hollow tube in order form a seal between the flexible sheet and the wound. The systems may also include microelectronic mechanical valves for releasing the debridement substance from the bladder.

Abstract: A device and method for performing stenting and intubation of the nasolacrimal system to treat for stenosis or obstruction includes a semi-rigid tubular guide sleeve through which a flexible tubular stent, having an oversized length, is inserted from a punctal opening into the nasal cavity. The guide sleeve is removed and a resilient, radially expandable punctal anchor is placed through the punctal opening, to contact the stent and hold it in place. An introducer device having a hollow tubular core and a coaxially mounted, axially translatable outer sheath is provided to facilitate placement of the anchor. The anchor is stretched over the distal end of the core and the stent threaded into the central lumen of the core. Once the anchor is in place, the sheath is translated to push the anchor off the distal end. Excess stent at its proximal end is then trimmed off.

Abstract: An applicator device for applying a fluid is provided. The applicator device may include a handle. The handle may comprise an elongate hollow body having a proximal end and a distal end and at least one longitudinal, interior rib disposed on an inner surface of an outer wall of the hollow body and configured to orient and guide a container for containing the fluid when the container is disposed within the hollow body. In addition, the applicator device may include a base at the distal end of the hollow body. Further, the applicator device may include an applicator pad coupled to the base.

Abstract: A closed system for harvesting fat through liposuction, concentrating the aspirate so obtained, and then re-injecting the concentrated fat into a patient comprises as its main components a low pressure cannula having between about 7 to 12 side holes of about 1-2 mm by 2.0 to 4.0 mm, a spring loaded syringe holder with a constant force or coiled ribbon spring to apply a substantially constant pressure over the full excursion of the plunger, and a preferably flexible collection bag which is also preferably graduated, cylindrical over most of its body and funnel shaped at its bottom, all of which are connected through flexible tubings to a multi-port valve. The multi-port valve has two flutter/duck bill valves which restrict the fluid flow to a one way direction which effectively allows the syringe to be used to pump fat out of a patient and into a collection bag in a continuous manner.

Abstract: A tissue closure treatment system and method are provided with an external patient interface. A first fluid transfer component FTC.1 comprises a strip of porous material, such as rayon, with liquid wicking properties. FTC.1 can be placed directly on a suture line for transferring fluid exuded therethrough. An underdrape is placed over FTC.1 and includes a slot exposing a portion of same. FTC.2 comprises a suitable hydrophobic foam material, such as polyurethane ether, and is placed over the underdrape slot in communication with FTC.1. Negative pressure is applied to FTC.2 through a connecting fluid, transfer component FTC.3. A negative pressure source can comprises a manual device or a power-operated suction device. The tissue closure method includes a manual operating mode using a manual suction device with an automatic shut off for discontinuing suction when a predetermined volume of fluid has been drained.

Abstract: A controller is operable to selectively supply gas to, and evacuate gas from, regions of a hyperbaric wound treatment chamber. The controller operates to inflate a passage or rib of the device to provide that the device is made sufficiently rigid for inserting a limb therethrough, and inflate an inflatable cuff to create a seal against the limb. The controller also operates to evacuate ambient air trapped within the chamber, and optionally partially evacuate the passage or rib, after the seal is created by the inflatable cuff, and then introduce oxygen into the chamber, and optionally inflate the passage or rib. The cuff, when inflated and creating a seal against a limb, optionally is at least partially within the chamber, and the treatment gas is supplied to the chamber to maintain the seal of the cuff against the limb.

Abstract: A disposable absorbent article for receiving urine from an individual and a method of using the same are described. The absorbent article can include an absorbent body folded substantially longitudinally. The absorbent body can include a left-side portion and a right-side portion on opposite sides of the fold, and a proximal edge extending generally orthogonal to the fold. An interior receiving cavity can be defined by the left-side portion and the right-side portion of the folded absorbent body. The absorbent article also includes a penile opening defined by a portion of the proximal edge, where the penile opening is adapted for receiving a penis of a user into the interior receiving cavity. The absorbent body can include a liquid impermeable, exterior layer; a liquid permeable, fluid management layer; and an absorbent layer disposed between said exterior layer and said fluid management layer.

Abstract: A medical device includes a longitudinal axis member, a suction member that is provided at a distal end of the longitudinal axis member, has a contact surface capable of coming into close contact with an inner wall of a bursiform cavity when inserted into the bursiform cavity, and has a plurality of communication passages that are open to the contact surface and communicate with a lumen, a suction source provided at a proximal end of the longitudinal axis member so as to be connected to the lumen, and a closing member that is provided at an axial end of the suction member, comes into contact with the opening, and airtightly seals the opening.

Abstract: A portable microbubble and drug mixing device is provided. The portable microbubble and drug mixing device comprises a flexible outer container comprising an interior chamber for accommodating a drug, and a rigid inner container within the flexible outer container and comprising an interior chamber for accommodating microbubbles. The outer container has a tensile strength at break less than or equal to approximately 15 MPa, and the inner container has a tensile strength at break greater than or equal to approximately 20 MPa and is capable of storing microbubbles at a concentration higher than or equal to approximately 5×106 microbubbles/ml. The inner container is configured to separate the microbubbles in the interior chamber of the inner container from the drug in the interior chamber of the outer container until a point of mixing when the microbubbles are released into the interior chamber of the outer container.

Abstract: A withdrawal catheter and method for removing a material from a specific area includes a first tubing positioned within a second tubing. The first and second tubing has a plurality of holes for withdrawal of the material, such as fluid and small particulates. The first and second tubing may have different wall thicknesses, and the holes may be positioned staggered and have different diameters. At least one of the first and second open ends of the first tubing is connected to a fastener, having a bore for passage of material therethrough. A third tubing is attachable to the fastener for providing a path for the flow of the material from the first and second tubing. The material is aspirated through the first tubing for withdrawing the material. The second tubing substantially prevents larger pieces of material from contacting the first tubing and clogging the holes of the first tubing.

Abstract: Devices, methods, and systems for treating Type-2 Diabetes and/or obesity by facilitating the delivery of under-digested nutrients within the gastro-intestinal tract without substantial tissue removal are disclosed. In one aspect, the gastro-intestinal tract of a patient is modified by a gastro-intestinal treatment device comprising an elongate element configured to extend within the gastro-intestinal tract, a first attachment element and a second attachment element disposed on the elongate element, wherein the first attachment element and the second attachment element are configured to attach to the gastro-intestinal tract such that a portion of the gastro-intestinal tract is compressed between the first and the second attachment elements. The length of the gastro-intestinal tract modified by the device is effectively shortened, and its surface area is reduced.

Abstract: The illustrative embodiments described herein are directed to systems, methods, and apparatuses for applying a reduced pressure to a subcutaneous tissue site. In one instance, a manifold for applying reduced pressure to a subcutaneous tissue site includes a plurality of first conduits, each of the plurality of first conduits having a wall with at least one first aperture and at least one second aperture. At least one of the plurality of first conduits is operable to deliver reduced pressure to the subcutaneous tissue site. The plurality of first conduits is coupled in a spaced arrangement that forms an interior space. The manifold further includes a second conduit comprising the interior space and formed by a portion of each wall of the plurality of first conduits. The second conduit is in fluid communication with the plurality of first conduits via the at least one second aperture.

Abstract: A multiple layer laminate and method of manufacturing the same having visible indicia for use in an absorbent article includes a first outer layer, a second outer layer, an elastomeric film interposed between said first outer layer and said second outer layer and a non-elastomeric appliqué having the indicia. The non-elastomeric appliqué is interposed between the elastomeric film and the first outer layer or between the elastomeric film and the second outer layer. The non-elastomeric appliqué is coupled to the elastomeric film in a stretched condition such that the non-elastomeric appliqué limits the retraction of the elastomeric film from the stretched condition in a location where the non-elastomeric appliqué is coupled to the elastomeric film, wherein the indicia is positioned to be visible through the first outer layer, the second outer layer or the first and the second outer layers.

Abstract: An implantable MEMS package for the treatment of an ocular condition is provided. The MEMS package includes an outer portion; an active portion attached to the outer portion, the active portion including a fluid regulating element having a moving element; and a fluidic channel at an interface of the outer portion and the active portion. The fluidic channel is formed in at least one of the outer and active portions and permits fluid communication from the MEMS package to the fluid regulating element. A method for forming a MEMS package as above is also provided. An ocular implant for treating glaucoma including an inlet tube for receiving aqueous humor; a MEMS package as above, coupled to the inlet tube; a control system to control the MEMS package; and an outlet tube for draining aqueous humor at a drainage location, is provided.

Abstract: Described are embodiments that include a device with a motor that when connected to a cannula rotates the cannula while removing adipose tissue from a surgical site. The device provides a direct pathway, for aspirated adipose tissue, from a tip of the cannula to a location where tubing is attached to the device. The pathway does not pass through the motor that provides the angular rotation of the cannula. Instead, the path for the adipose tissue passes through a removable coupler that is connected to the cannula. The embodiments provide a cannula that rotates but also has a direct flow path for adipose tissue that does not pass through the motor.

Abstract: The present invention provides a device, a system, and a method for application of fluids.