Patents Examined by Benjamin L Lebron
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Patent number: 11840502Abstract: The present disclosure provides a system for efficiently preparing taurine, including: a solution storage unit configured to store a solution containing alkali metal taurinate, the solution being prepared by an ethylene oxide process; an ion exchange unit including at least one ion exchange resin column each configured to be activated by a first activation manner or a second activation manner independently, the first activation manner using sulfurous acid for activation to obtain alkali metal bisulfate and taurine, and the second activation manner using sulfuric acid for activation to obtain alkali metal sulfate and taurine; and a dispensing unit connected to the solution storage unit and the ion exchange unit respectively, and configured to adjust an amount of a solution conveyed from the solution storage unit to each of the at least one ion exchange resin column in the ion exchange unit.Type: GrantFiled: June 24, 2022Date of Patent: December 12, 2023Assignee: HUBEI GRAND LIFE SCIENCE AND TECHNOLOGY CO., LTD.Inventors: Huajun Sun, Min Tan, Xiaojing Yan, Ruyong Jiang, Hongbo Peng, Jiale Tang, Chen Guo, Xingxing Wang, Zhiqiang Qian
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Patent number: 11839836Abstract: Chromatography column components are described. One component, a chromatography plug, can include a body, the body including: a first surface; a second surface opposing the first surface; a passage through the body extending from an opening in the first surface to an opening in the second surface; and a circumferential surface extending from the first surface to the second surface; a plurality of ridges, located on the first surface, wherein each of the plurality of ridges having a first end and an opposed second end, and the first end of each of the plurality of ridges being closer to one another than the second ends of each of the plurality of ridges. In some instances, a bridge can be located between the first ends, the bridge extending into the body. A porous partition can be located on or in the plug.Type: GrantFiled: November 17, 2017Date of Patent: December 12, 2023Assignee: Bio-Rad Laboratories, Inc.Inventors: Pascal Wijnant, John Tipton, Christopher Ward
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Patent number: 11837756Abstract: An ion filter for a fuel-cell stack, which is configured for overcoming restrictions related to hydraulic head on the ion filter in a fuel-cell system and has a simplified structure, may include a manifold unit of diverging a coolant introduced from an outside; and an ion filter unit connected to the manifold unit to receive the coolant from the manifold unit and including a cartridge assembly having an ion filter resin.Type: GrantFiled: August 17, 2021Date of Patent: December 5, 2023Assignees: Hyundai Motor Company, Kia Corporation, Mahle Donghyun Filter Systems Co., Ltd.Inventors: Hyun Ju Ji, Hun Woo Park, Sun Ae Park, Hwan Choi
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Patent number: 11827541Abstract: The present embodiments generally relate to the treatment of produced water comprising one or more water soluble polymers, wherein such treatment comprises: adding to the produced water at least one iron complex; and degrading at least a portion of the one or more water soluble polymers. This treatment may result in a reduction of the viscosity of said produced water and/or the degradation of the water soluble polymers which are contained therein.Type: GrantFiled: May 5, 2022Date of Patent: November 28, 2023Assignee: KEMIRA OYJInventors: Iris Porat, Miguel Pelaez, Mehrdad Hesampour, Yuping Luo, William Morris, Luciana Bava
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Patent number: 11819779Abstract: A chromatographic separation method for separating plural components contained in a liquid to be separated by a chromatography, with a separating device 1 including plural filling portions 10 filled with a separating agent for separating the plural components contained in the liquid to be separated, a supply portion 20 provided in each of the plural filling portions 10 to supply the liquid to be separated or an eluent for extracting any component contained in the liquid to be separated to the filling portion 10, and an extraction portion 30 to extract any component contained in the liquid to be separated from the filling portion 10, the method including: an upward supplying and extracting step of extracting any component contained in the liquid to be separated from an upward stream extraction portion while supplying the eluent to at least one filling portion 10 from an upward stream supply portion by an upward stream.Type: GrantFiled: February 28, 2019Date of Patent: November 21, 2023Assignee: Mitsubishi Chemical Aqua Solutions Co., Ltd.Inventors: Keiji Iwamoto, Makoto Yasumoto, Toshihiko Uratsuji
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Patent number: 11820679Abstract: Disclosed are an energy self-sufficient high-efficiency photothermal evaporative nano-particle porous membrane and application thereof, including: dissolving polymer A in solvent B to obtain solution A; dripping solution A into solvent C to obtain a polymer A nano hydrogel dispersion; evenly mixing polymer A nano hydrogel dispersion and nano particle dispersion of photothermal conversion material D to obtain a co-blended dispersion; performing suction-filtering to the co-blended dispersion on a surface of a solvent-resistant membrane E to form an A-D co-blended membrane; and performing suction-filtering to a solvent F using the A-D co-blended membrane, followed by drying to obtain a high-efficiency photothermal evaporative nano-particle porous membrane.Type: GrantFiled: February 27, 2023Date of Patent: November 21, 2023Assignee: Institute of Eco-environmental and Soil Sciences, Guangdong Academy of SciencesInventors: Bin He, Yu Ma
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Patent number: 11813588Abstract: A chromatographic material including a substrate having a surface and having a polymeric layer covalently bound to the surface; the polymeric layer comprising polymer molecules covalently attached to the surface of the substrate, each polymer molecule being attached to the surface via multiple siloxane bonds and each polymer molecule being connected to one or more functionalizing compounds that each comprise a functional group, wherein the polymeric layer is formed by covalently attaching polymer molecules to the surface of the substrate via multiple siloxane bonds, each polymer molecule containing multiple first reactive groups, and reacting the first reactive groups of the attached polymer molecules with at least one functionalizing compound that comprises a second reactive group that is reactive with the first reactive groups and that further comprises a functional group. Preferred conditions of reacting the polymer with the substrate include elevated temperature and reduced pressure.Type: GrantFiled: January 11, 2021Date of Patent: November 14, 2023Assignee: Dionex CorporationInventors: Xiaodong Liu, Xiao Cui, Xuefei Sun
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Patent number: 11806461Abstract: Provided is a blood purification device including a porous molded body that has a high phosphorus adsorption capacity and that can be used safely. A blood purification device includes a porous molded body containing an inorganic ion-adsorbing material and is characterized by the following: said blood purification device satisfies the relationship B=?0.02 A+2.175±0.185 (74?A?94) when the moisture content of the porous molded body is denoted by A and the bulk density is denoted by B; and the number of fine particles having a size of 10 ?m or more is 25 or less and the number of fine particles having a size of 25 ?m or more is 3 or less in 1 mL of a physiological saline solution for injection both three months and six months after said physiological saline solution for injection is sealed in the blood purification device.Type: GrantFiled: March 29, 2019Date of Patent: November 7, 2023Assignee: ASAHI KASEI MEDICAL CO., LTD.Inventors: Teruhiko Oishi, Naoki Morita, Keitaro Matsuyama, Hiroshi Tajima, Toshinori Koizumi
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Patent number: 11801505Abstract: A cation exchange chromatographic matrix comprising a base material, and a copolymer with one monomer unit having at least a sulfonic acid group, the copolymer being immobilized on the base material, wherein: the copolymer forms substantially no cross-linked structure, and the copolymer comprises neither acrylamide nor an acrylamide derivative as a monomer unit, or comprises acrylamide or an acrylamide derivative as a monomer unit in a range which has no substantial influence; the ratio of the mass of the copolymer to the mass of the base material is 5% or more and 200% or less; and the density of the sulfonic acid group is higher than 30 mmol/L and 200 mmol/L or lower.Type: GrantFiled: January 7, 2022Date of Patent: October 31, 2023Assignee: ASAHI KASEI MEDICAL CO., LTD.Inventor: Hiroki Taniguchi
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Patent number: 11794165Abstract: The present disclosure provides a porous silica having an average pore diameter of at least 210 ? and a pore volume of at least 0.80 cm3g?1. The present disclosure also provides a method of producing the porous silica including gelling a liquid phase-dispersed nanoparticulate silica in the presence of either (i) a Brønsted acid and an amine group having two or more primary or secondary amine groups or (ii) an amino acid.Type: GrantFiled: May 28, 2020Date of Patent: October 24, 2023Assignee: NOURYON CHEMICALS INTERNATIONAL B.V.Inventors: Joakim Erik Patrik Högblom, Peter Lennart Gidlund, Börje Sigvard Persson
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Patent number: 11786842Abstract: A composition includes a hybrid ligand. The hybrid ligand includes an amine group, an amide group or a sulfonamide group, and hydroxyl groups. A first method includes providing a solution containing a first polar analyte and a second polar analyte, applying the solution to a stationary phase including an immobilized hybrid ligand, applying an elution solvent to the stationary phase such that the first polar analyte and the second polar analyte pass through the stationary phase with different elution times, and collecting the first polar analyte at a first elution time and collecting the second polar analyte at a second elution time after the first elution time. A device of a packed column, a cartridge, a tube, a well plate, a membrane, or a planar thin-layer chromatography plate includes a solid support and a hybrid ligand coupled to the solid support. A second method forms an immobilized hybrid ligand.Type: GrantFiled: May 11, 2020Date of Patent: October 17, 2023Assignee: RESTEK CORPORATIONInventors: Xiaoning Lu, Charles Vernon Bartlett, Connor Flannery, Ahren Iver Green, Terrence Scott Reid
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Patent number: 11782031Abstract: A detector for a liquid chromatograph includes a detector that detects components in liquid, and a heat exchanger that adjusts a temperature of liquid introduced into the detector, wherein the heat exchanger includes a pipe having a winding portion, and a cast in which the winding portion is embedded, the pipe is formed of resin, and the cast is formed of an alloy having a melting point lower than a continuous use temperature of the resin.Type: GrantFiled: January 14, 2022Date of Patent: October 10, 2023Assignee: Shimadzu CorporationInventor: Yuki Iijima
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Patent number: 11774413Abstract: A preparative liquid chromatograph includes a liquid chromatograph section, a trap section, an eluent supply section, a collector, and a flow path switching section. The flow path switching section is configured to be selectively switched to a component trap mode that connects the liquid chromatograph section and the trap section in such a way that a sample component separated in a separation column is trapped by a trap column of the trap section; and a collection mode that connects the eluent supply section and the trap section and connects the trap section and the collector in such a way that the components trapped in the trap column are eluted by an eluent from the eluent supply section and are guided to the collector.Type: GrantFiled: July 2, 2021Date of Patent: October 3, 2023Assignee: Shimadzu CorporationInventor: Tomoyuki Yamazaki
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Patent number: 11740210Abstract: Disclosed is a chromatography system (100) comprising: plural modules (1-25) including at least one pump and a column valve unit (8) connectable to plural chromatography columns; and a controller (600), the controller being operable to control the or each pump and the column valve to perform different chromatographic processes, including chromatography employing just one column, as well as chromatography employing two or more columns by selective valve opening in said unit. The system includes a housing (110) into which the plural modules (1-25) are interchangeably mountable in apertures of one generally vertical face of housing, the modules are adapted for selective fluidic interconnection by tubing substantially at said one face such that in use the modules and tubing occupy a generally vertically extending volume to minimize the footprint of the system.Type: GrantFiled: September 21, 2018Date of Patent: August 29, 2023Assignee: CYTIVA SWEDEN ABInventors: Nils Stafstrom, Lars Olof Nils Rosengren, Kerstin Elisabet Erickson, Tomas Yngve Agren, Yngve L. Hareland, Tim Francois, Anita Jonsson, Jeanne Cheng, Anna Andersson
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Patent number: 11731108Abstract: The subject invention pertains to proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic 1,3-dioxoisoindolin-2-yl group functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of one, two, three, four, or five atoms between the hydrophobic group and the support matrix.Type: GrantFiled: March 17, 2022Date of Patent: August 22, 2023Assignee: BIO-RAD LABORATORIES, INC.Inventors: Christopher Belisle, Jiali Liao, Edwin Lozano
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Patent number: 11731062Abstract: A chromatography and synthesis column that includes a main tube, a plurality of lower media ports, and an internal groove. The internal groove is formed in an interior surface of the main tube and selectively provides an internal flow path between each of the internal lower media ports. This, in turn, facilitates quick and easy maintenance of the internal lower media ports and other components of the chromatography and synthesis column.Type: GrantFiled: January 20, 2021Date of Patent: August 22, 2023Assignee: Asahi Kasei Bioprocess America, Inc.Inventor: Michael D. Brandt
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Patent number: 11731107Abstract: A system and method of applied radial technology chromatography using a plurality of beads is disclosed, with each bead comprising one or more pores therein having a diameter of about 250 ? to about 5000 ?, and each bead having an average radius between about 100 ?m to about 250 ?m. Also disclosed are processes for selecting beads for use in a radial flow chromatography column, and for purifying an unclarified feed stream using a radial flow chromatography column.Type: GrantFiled: April 7, 2022Date of Patent: August 22, 2023Assignee: emp Biotech GmbHInventors: Alistair J. Hurst, Derek W. K. Levison
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Patent number: 11733216Abstract: Thermally modulated variable restrictors used in chromatography systems enable independent control of system pressure and linear velocity of a compressible mobile phase passing through a chromatography column. A method for configuring a chromatography system with independent control of system pressure and mass flow rate of a compressible mobile phase includes determining a type of chromatography separation column to be used in the chromatography system, matching a thermally modulated variable restrictor to the type of chromatography separation column for use together during operation of the chromatography system, and bundling the chromatography column with its matching thermally modulated variable restrictor for distribution as a single package.Type: GrantFiled: June 30, 2020Date of Patent: August 22, 2023Assignee: Waters Technologies CorporationInventors: Michael O. Fogwill, Joseph D. Michienzi, Geoff Gerhardt, James P. Murphy
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Patent number: 11718643Abstract: The invention discloses a separation matrix which comprises a plurality of separation ligands, defined by the formula R1-L1-N(R3)-L2-R, immobilized on a support, wherein R1 is a five- or six-membered, substituted or non-substituted ring structure or a hydroxyethyl or hydroxypropyl group; L1 is either a methylene group or a covalent bond; R2 is a five- or six-membered, substituted or non-substituted ring structure; L2 is either a methylene group or a covalent bond; R3 is a methyl group; and wherein if R1 is a hydroxyethyl group and L1 is a covalent bond, R2 is a substituted aromatic ring structure or a substituted or non-substituted aliphatic ring structure.Type: GrantFiled: November 11, 2013Date of Patent: August 8, 2023Assignee: Cytiva BioProcess R&D ABInventors: Jean-Luc Maloisel, Gustav Rodrigo, Bjorn Noren, Virendra Kumbhar
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Patent number: 11717770Abstract: A variable fluidic restrictor of a liquid chromatography system including a stator body, the stator body include a plurality of fluidic channels located within the stator body, wherein each fluidic channel of the plurality of fluidic channels includes a restrictor element, wherein a flow of a fluid through the variable fluidic restrictor is selectively restricted based on a position of an external element coupled to the stator body is provided. Furthermore, an associated method is also provided.Type: GrantFiled: April 8, 2022Date of Patent: August 8, 2023Assignee: Waters Technologies CorporationInventors: Zongren Shang, Stanislaw Koziol, Joseph D. Michienzi, Michael Eggertson, Keith Fadgen