Abstract: The combination of a breast pump shield, with its ring, applied to the flange lower end of the shield, and the ring being C shaped in cross-section, having an upper flange, a lower flange, both integrally structured with a base wall. The physiological stimulator integrally formed with the lower flange of the sealing ring extends inwardly and upwardly within the shield, and therein functions as a means to place pressure upon the breast of the mother to help induce and stimulate the flow of breast milk during usage of the associated breast pump.

Abstract: A device for supporting IV tubing along a distance and suspending the tubing above the floor includes a support arm and a cradle. The cradle is positioned along a shaft of the support and is configured to receive a length of IV tubing therein.

Abstract: A system for providing the collection of advanced, improved, and novel new components and elements in a single package to simplify assembly and use of the infusion set by the user, including one or more of an exemplary pushbutton-type inserter, squeeze-type inserter, contact-type inserter, skin pinching-type inserter, folding retraction-type inserter, and/or multistage-type inserter (700) having at least one reusable stage, an exemplary set (350) having an adhesion means with two or more user-selectable degrees of adhesion strength, a self-sealing tube connection means, a lens feature to view a site beneath the set, exemplary tube management and connection elements (450), insulin supply (475), adhesion concealment means (500), finger loops on the inserter and site preparation wipes or sprays (550) which can be provided as part of the inserter.

Abstract: A method and device for electroporating adipocytes in the adipose layer of tissue, where the device includes a frame, a first electrode coupled to the frame having a first contact surface, a second electrode coupled to the frame having a second contact surface, and where the first contact surf ace and the second contact surface define a treatment zone therebetween. The method including positioning a fold of tissue between the first and second electrodes such that the treatment zone formed between the two electrodes includes an adipose layer of tissue and no skeletal muscle.

Abstract: An apparatus and method for a sleeve for use with a phacoemulsification handpiece, the sleeve having a body portion suitable for engaging a handpiece is disclosed. The tip portion of the sleeve may comprise at least one aspiration port and at least one rounded portion which may be suitable for use for surgery of the eye, and, more particularly, for use around the edge of a capsular bag.

Abstract: Drive systems for a drug delivery device are provided. The drive systems can be positioned within a container that stores a liquid drug to be delivered to a user. The drive systems can be coupled to a plunger positioned within the container. The drive systems can be incrementally advanced to drive the plunger further into the container, thereby expelling a portion of the stored liquid drug from the container for delivery to the user. The container can be any type of container including a pre-filled, standardized drug cartridge. The drive systems and container can be components of a wearable drug delivery device.

Abstract: A degradation data generator is used with a scaffold for delivery within a patient. The degradation data generator includes a driving circuit electrically coupled to drive an impedance of the scaffold. A detection circuit generates degradation data based on the impedance of the scaffold or other properties such as RF or lightwave transmission, conductance or absorption. The degradation data indicates an amount of biodegradation of the scaffold. A wireless transmitter is coupled to transmit the degradation data to a wireless degradation data receiver, while the scaffold is within the patient.

Abstract: A medical instrument includes first and second knobs. The first knob is fitted on a handle of the medical instrument, and is movable along a longitudinal axis of the medical instrument to control a deflection of a medical device coupled to a distal end of the medical instrument relative to the longitudinal axis. The second knob is fitted on the handle of the medical instrument, and is movable along the longitudinal axis to control a shape of the medical device.

Abstract: The present invention relates to a stopper for an injector for delivery of a pharmaceutical composition and to an injector with the stopper. The stopper has a stopper body with an actuating surface opposite an outlet surface, an axial length between the actuating surface and the outlet surface, and a transverse diameter, which stopper body defines an access diameter, the stopper at an axial location from the actuating surface comprising a deformable sealing element surrounding the stopper body and having an outer diameter, which is larger than the transverse diameter, which deformable sealing element is made from a thermoplastic elastomer and has an axial extension in the range of 5% and 95% of the axial length of the stopper body, and the stopper comprising a cavity at the axial location of the deformable sealing element, the cavity having a lateral extension larger than the access diameter of the stopper body.

Abstract: A container for an injectable medicament is provided. The container can include an elongated body having a tubular-shaped sidewall extending along a longitudinal axis and having a distal end and a proximal end. The container can include an outlet at the distal end and a bung arranged inside the elongated body, sealingly engaged with the sidewall and slidable along the longitudinal axis relative to the sidewall. The container can include an interior volume to receive the injectable medicament and being confined by the sidewall, the outlet, and the bung. The container can include a measuring arrangement arranged in or on the bung. The measuring arrangement can include a signal generator configured to emit a measurement signal into or through the interior volume, the measurement signal being capable to stimulate or to excite a resonance of the container.

Abstract: The present specification relates to a drug delivery device including a housing adapted to receive a primary container with a piston, a plunger slidably disposed in the housing and adapted to drive the piston for delivering a medicament, a drive spring pre-loaded between the housing and the plunger so as to urge the plunger in a distal direction, an audible and/or tactile indicator, and a trigger mechanism arranged between the indicator and the plunger. The trigger mechanism is configured to support the indicator in an initial state of the device and during delivery of the medicament and to couple with the plunger to activate the audible and/or tactile indicator at or near an end of delivery.

Abstract: A microprojection array comprising a substrate with a plurality of microprojections protruding from the substrate wherein the microprojections have a tapering hexagonal shape and comprise a tip and a base wherein the base has two substantially parallel sides with a slight draught angle of approximately 1 to 20 degrees up to a transition point at which point the angle increases to from about 20 degrees to about 70 degrees.

Abstract: Medical devices capable of filling liquid into a syringe barrel while evacuating any air from the syringe are described. An exemplary medical device includes a syringe barrel having a tapered sidewall portion for permitting air to vent from the chamber and preventing liquid from exiting the chamber, a plunger rod, and stopper. Another exemplary medical device includes a syringe barrel having a plurality of air venting grooves associated with the sidewall of the barrel, a plunger rod and stopper. Also described is a medical device including a syringe barrel, plunger rod and stopper having a porous plug. Described is a medical device including a syringe barrel having a plurality of air venting grooves associated with the sidewall of the barrel and a porous membrane disposed over the air venting grooves, a plunger rod and stopper. Methods for filling a syringe barrel with a liquid are also provided.

Abstract: An injection device including: a body including a syringe locator for receiving a syringe; and a firing mechanism including a rear cap, a plunger configured to be axially displaced in a forward direction relative to the rear cap and a driver system for driving the plunger forwards upon activation of the injection device, the firing mechanism configured to be directly or indirectly connected to the body such that an axial spacing of the rear cap and a barrel of the syringe is fixed during operation of the injection device, wherein, the firing mechanism and/or the body include first and second connection features allowing adjustment of a relative axial position of the firing mechanism and the syringe locator during assembly of the injection device.

Abstract: A drive unit for a medicament delivery device is presented having an elongated plunger rod extending in a longitudinal direction, a drive force element capable of applying a drive force on the elongated plunger rod, and an actuator operably connected to the elongated plunger rod for releasably holding the elongated plunger rod in an energized state when the drive force element is exerting a drive force on the elongated plunger rod. An activator is operably connected to the actuator for releasably holding the actuator in a holding position where the actuator is designed to be movable from the holding position in a direction generally transversal to the longitudinal direction upon a displacement of the activator for releasing the plunger rod.

Abstract: A breast shield for a breast pump for expressing human breast milk comprises a rigid base part (1) with a tubular connection piece (10) and with a funnel (11), which is integrally moulded in one piece thereon and widens away from the connection piece (10), for receiving a breast. The breast shield additionally comprises a flexible collar (2) which is arranged on the funnel (11) at an end of the funnel (11) remote from the connection piece (10) and which is realized to be placed onto the mother's breast. The named end of the funnel (11) forms a first contact surface (12) and an end of the collar (2) which faces the funnel (11) forms a second contact surface (22) and they both adjoin one another in an obtuse manner in a circumferential connecting joint (4), wherein the connecting joint is a butt joint.

Abstract: A drug delivery assembly includes a main body and a cartridge. The body includes a housing, an adhesive pad, and a body interface that detachably associates with a cartridge interface of the cartridge. A fluid flow path extends through the body housing, between a first end configured to open a seal of the cartridge and a second end configured to enter a human body. The cartridge contains a drug reservoir having an outlet and holding a medicament. The seal prevents the medicament from exiting the reservoir and maintains pressure within the reservoir until the seal is opened by the first end of the fluid flow path when the cartridge is coupled to the main body, placing the reservoir into fluid communication with the flow path. A controller actuates a valve within the body to selectively allow and prevent flow through the flow path during an automated drug delivery routine.

Abstract: The present invention concerns a drug delivery device (1) comprising: a housing (2) extending along a main axis, a torsion spring (5) comprising a first spring end (4) arranged stationarily with respect to the housing (2) and a second spring end (6) capable of rotation about the main axis, a rotatable shaft (80) extending along the main axis, the rotatable shaft (80) having a non-self-locking thread (81) and being axially fixed with respect to the housing (2), a spring end retainer (82) to which the second spring end (6) is attached, the spring end retainer (82) being rotationally fixed relative to the rotatable shaft (80), and a nut member (45) engaged with the non-self-locking thread (81), the nut member (45) being axially movable by translation relative to the housing (2) to thereby travel the non-self-locking thread (81) between a first position in which the torsion spring (5) is in a relaxed state and a second position in which the torsion spring (5) is in a strained state.

Abstract: The invention includes a dilator comprising a tube and an elastic, unitary sleeve that is slidable both longitudinally and transversely to the cylindrical barrel when disposed on the tube.

Abstract: In part, the disclosure relates to a safety monitor and related methods to evaluate and manage intrapartum uterine contractions induced or augmented by Pitocin or other contraction inducing agents. The systems and methods include measuring a contraction parameter that may include one or more of frequency, strength, and duration of uterine contractions through a measurement device connected to a monitor. The systems and methods are programmed to stop the pump-based administration of a contraction inducing agent. Various lock out protocols and control over the ability to re-start a given pump are also described herein.