Patents Examined by Blessing Fubara
  • Transparent water-silicon hair conditioning agent
    Patent number: 6602494
    Abstract: An optically clear, transparent or translucent hair conditioner in the form of a water-in-silicone oil emulsion is described. Said hair conditioner contains a silicone surfactant, a hydrophobic, nonsurfactant silicone compound present in the hair conditioner in liquid form, a basic or cationic nitrogen atom-containing hair-conditioning compound, a nonionic, silicone-free surfactant, a polyhydric alcohol and an electrolyte. The hair conditioner can be used as a leave-in hair treatment or as a hair rinse.
    Type: Grant
    Filed: January 9, 2002
    Date of Patent: August 5, 2003
    Assignee: Wella AG
    Inventors: Mehrdad Jahedshoar, Jennifer Imperial, Juergen Schmenger, Karin Steinbrecht, Wilhelm Abels
  • N-maleimidyl polymer derivatives
    Patent number: 6602498
    Abstract: The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a N-maleimidyl moiety without a linking group therebetween. The invention also provides two methods of preparing such linkerless N-maleimidyl polymer derivatives.
    Type: Grant
    Filed: February 21, 2001
    Date of Patent: August 5, 2003
    Assignee: Shearwater Corporation
    Inventor: Xiaoming Shen
  • Therapeutic azo-compounds for drug delivery
    Patent number: 6602915
    Abstract: Polyazo compounds, which include low molecular weight drugs having a carboxylic acid group and an amine, thiol, alcohol or phenol group within their structure, formed into polymeric drug delivery systems are provided. Also provided are methods of producing polymeric drug delivery systems having these polyazo compounds as well as methods of administering low molecular weight drugs to a host via the polymeric drug delivery systems.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: August 5, 2003
    Assignee: Rutgers, The State University of New Jersey
    Inventor: Kathryn E. Uhrich
  • Biodegradable poly(alkylene oxide)-poly(p-dioxanone) block copolymer soluble in organic solvents, and drug delivery composition comprising same
    Patent number: 6599519
    Abstract: The present invention relates to a biocompatible and biodegradable block copolymer of poly(alkylene oxide) and poly(p-dioxanone), which is soluble in organic solvents, and a drug delivery composition comprising the same.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: July 29, 2003
    Assignee: Samyang Corporation
    Inventors: Min-Hyo Seo, In-Ja Choi
  • Iodinated resin held to a carrier
    Patent number: 6592861
    Abstract: The present invention relates to iodine demand disinfectants. It relates in particular to a process for preparing a polyiodide-resin for use as an iodine demand disinfectant wherein a porous strong base anion exchange resin in a salt form, is contacted with a material capable of donating a member absorbable by the resin so as to convert the resin to the polyiodide-resin. The adsorbable member is selected from the group comprising I2 and polyiodide ion having a valence of −1. The process is characterized in that conversion of the anion exchange resin to the polyiodide-resin is effected at elevated temperature and elevated pressure, the elevated temperature being 100 degrees C. or higher, the elevated pressure being greater than atmospheric pressure. The present invention also relates to disinfectant substance comprising an iodine (impregnated) resin as produced by the above process.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: July 15, 2003
    Assignee: Triosyn Holding Inc.
    Inventor: Pierre Jean Messier
  • Stabilized polyvinylpyrrolidone formulation
    Patent number: 6592900
    Abstract: Preparations in powder form comprising or consisting of soluble or insoluble polyvinylpyrrolidone and/or polyvinylpyrrolidone copolymers and suitable as aid for pharmaceutical formulations comprise in homogeneous dispersion very small amounts of heavy metals which are physiologically tolerated in these amounts, or very small amounts of peroxide-cleaving enzymes.
    Type: Grant
    Filed: January 3, 2001
    Date of Patent: July 15, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Volker Bühler, Ulrich Filges, Tanja Schneider
  • PLA/PLGA oligomers combined with block copolymers for enhancing solubility of a drug in water
    Patent number: 6592899
    Abstract: Polymeric compositions having improved capability of solubilizing a drug in a hydrophilic environment to form a solution, comprising: a biodegradable polyester oligomer; and biodegradable AB-type, ABA-type, or BAB-type block copolymers are disclosed. The copolymers are comprised of about 50.1 to 65% by weight of a biodegradable, hydrophobic A polymer block comprising a biodegradable polyester, and about 35 to 49.9% by weight of a hydrophilic B polymer block comprising a polyethylene glycol (PEG), and wherein the block copolymer has a weight averaged molecular weight of between 2400 to 4999. The biodegradable polyester oligomer of said composition is within a range of 0.01% to 30% by weight of the total polymer mixture, and the content of the biodegradable AB-type, ABA-type, or BAB-type block copolymer is within a range of 70% to 99.99% by weight of the total polymer mixture.
    Type: Grant
    Filed: October 3, 2001
    Date of Patent: July 15, 2003
    Assignee: Macromed Incorporated
    Inventors: Kirk Dee Fowers, Gaylen M. Zentner, Chung Shih, Ai-Zhi Piao
  • Rapid-melt semi-solid compositions, methods of making same and methods of using same
    Patent number: 6589556
    Abstract: A novel rapid-melt, semi-solid molded composition, including methods of making the same, and methods of using the same for the delivery of prophylactic and therapeutic active materials to a mammal wherein the prophylactic or therapeutic active is a psychotropic, a gastrointestinal therapeutic or a migraine therapeutic.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: July 8, 2003
    Assignee: Capricorn Pharma, Inc.
    Inventor: Subraman Rao Cherukuri
  • Gel composition for filling a breast milk duct prior to surgical excision of the duct or other breast tissue
    Patent number: 6589998
    Abstract: The invention is a gel composition for delivery to a breast milk duct prior to surgical excision of breast tissue including cancerous lesions. The invention also provides methods of mapping all or nearly all of a breast milk duct prior to surgical excision of breast tissue, and method of identifying part or all of a breast duct or ducts as a surgical aide to a breast surgeon. Kits to support these methods and including these compositions are also provided.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: July 8, 2003
    Assignee: Cytyc Health Corporation
    Inventors: Annette Bianchi, Julian Nikolchev, David Hung, Eyal Ron, Linda Gont, Susan Love, Tina Patel
  • Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles
    Patent number: 6589549
    Abstract: A composition and method for releasing a bio-active agent or a drug within a biological environment in a controlled manner is disclosed. The composition is a dual phase polymeric agent—delivery composition comprising a continuous biocompatible gel phase, a discontinuous particulate phase comprising defined microparticles and an agent to be delivered. A microparticle containing a bio-active agent is releasably entrained within a biocompatible polymeric gel matrix. The bioactive agent release may be contained in the microparticle phase alone or in both the microparticles and the gel matrix. The release of the agent is prolonged over a period of time, and the delivery may be modulated and/or controlled. In addition, a second agent may be loaded in some of the microparticles and/or the gel matrix.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: July 8, 2003
    Assignee: Macromed, Incorporated
    Inventors: Chung Shih, Gaylen Zentner
  • Compositions containing Boswellia extracts
    Patent number: 6589516
    Abstract: A composition suitable for use on the skin or hair comprising: a) at least one extract of a Boswellia plant or at least one boswellic acid; and b) a carrier selected from the group consisting of branched fatty alcohols containing 8 to 32 carbon atoms, branched fatty acids containing 8 to 32 carbon atoms, unsaturated fatty alcohols containing 12 to 24 carbon atoms, unsaturated fatty acids containing 12 to 24 carbon atoms and derivatives of said branched fatty alcohols, said branched fatty acids, said unsaturated fatty alcohols and said unsaturated fatty acids, or mixtures thereof.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: July 8, 2003
    Assignee: Quest International B.V.
    Inventors: Heather Eyre, Maxine Jayne Hills, Stephen David Watkins
  • Polyolefin additive composition comprising 3,4-dimethyl dibenzylidene sorbitol and rho-methyl dibenzylidene
    Patent number: 6586007
    Abstract: A specific combination of two different polyolefin clarifying and nucleating agents, namely 3,4-dimethyldibenzylidene sorbitol and p-methyldibenzylidene sorbitol is provided. Such a combination surprisingly provides improved clarification and crystallization temperatures to polypropylene articles and formulations, better than bis-p-methyldibenzylidene sorbitol alone and equivalent or better than 3,4-dimethyldibenzylidene sorbitol. Such a combination of compounds thus permits the utilization of a new additive for the purpose of modifying polyolefin properties, such as polypropylene clarification and nucleation. The inventive combination may be introduced within any polyolefin composition, again preferably polypropylene, which may then be molded into any shape or form. A method of producing a polyolefin plastic utilizing the inventive combination of compounds is also provided.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: July 1, 2003
    Assignee: Milliken & Company
    Inventors: K. David Lake, Jr., Nathan A. Mehl, Christopher Thomas Kochanowicz
  • Mixtures of phenolic and inorganic materials with antimicrobial activity
    Patent number: 6585989
    Abstract: Plastic films, fibers and articles are provided long-term antimicrobial activity with a combination of certain phenolic and inorganic antimicrobial agents. The plastic films, fibers and articles with antimicrobial activity exhibit superior resistance to discoloration, may be processed at high temperature, and maintain physical properties upon weathering, especially upon exposure to ultraviolet radiation.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: July 1, 2003
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Heinz Herbst, Urs Stadler
  • Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
    Patent number: 6586006
    Abstract: The present invention encompasses solid dose delivery systems for administration of guest substances. Preferred delivery systems are suitable for delivery of bioactive materials to subcutaneous and intradermal, intramuscular, intravenous tissue, the delivery system being sized and shaped for penetrating the epidermis. The delivery systems comprises a vitreous vehicle loaded with the guest substance and capable of releasing the guest substance in situ at various controlled rates. The present invention further includes methods of making and using the solid dose delivery systems.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: July 1, 2003
    Assignee: Elan Drug Delivery Limited
    Inventors: Bruce J. Roser, Camilo Colaco, Mohammed A. Z. Jerrow, Julian Blair, Jaap Kampinga, James Lewis Wardell, John Alistair Duffy
  • Method for manufacturing a powder component for cement for medical use, use of such powder component and such powder component
    Patent number: 6586009
    Abstract: A method for manufacturing the powder: component for a cement for medical use includes a liquid component containing a polymerizable substance and a powder component containing a plastic substance and an X-ray contrast medium. The liquid component and the powder component are mixed for providing a setting mass which is set to form the cement. In order to prevent the formed cement from releasing particles wearing on articulating or bearing surfaces adjacent ;the point of cementation, a water soluble, non-ionic X-ray contrast medium is mixed with the plastic substance, and for minimizing the risk of damaging the powder component during the sterilization, sterilizing by radiation of the powder component containing the X-ray contrast medium is carried through a negative pressure or in an inert gas atmosphere.
    Type: Grant
    Filed: November 21, 2000
    Date of Patent: July 1, 2003
    Assignee: Bone Support AB
    Inventor: Lars Åke Alvar Lidgren
  • Taste masked pharmaceutical liquid formulations
    Patent number: 6586012
    Abstract: A liquid composition for oral administration comprising a pharmaceutically active medicament coated with a taste masking effective amount of a polymer blend of (a) dimethylaminoethyl methacrylate and neutral methacrylic acid ester (MM/MAE) and (b) a cellulose ester, in an aqueous vehicle, wherein the polymer weight ratio of the cellulose ester to the MM/MAE is about 40:60 to about 90:10, preferably about 60:40. The liquid composition utilizes a “reverse enteric coating” which is soluble in the acid pH's of the stomach, generally about 1.0 to 4.0, but relatively insoluble at the non-acidic pH's of the mouth. The coatings provide for rapid release and absorption of the drug, which is generally desirable in the case of liquid dosage forms.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: July 1, 2003
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Danny Yu, Edward Roche
  • Controlled release neurotoxin system
    Patent number: 6585993
    Abstract: A biocompatible implant for continuous in vivo release of a neurotoxin over a treatment period extending from one month to five years. The implant can be made of casting a solution of a polymer, such as an ethyl vinyl acetate copolymer and the neurotoxin. The neurotoxin can be a botulinum toxin.
    Type: Grant
    Filed: March 11, 2002
    Date of Patent: July 1, 2003
    Assignee: Allergan, Inc.
    Inventors: Stephen Donovan, Daniel G. Brady
  • Adhesive treatment for tinea cruris
    Patent number: 6585967
    Abstract: A method of treating or preventing tinea cruris, commonly known as Jock Itch, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea cruris, optionally with at least one of an additional anti-fungal agent or a skin care additive, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: July 1, 2003
    Assignee: Closure Medical Corporation
    Inventors: Upvan Narang, William S. C. Nicholson, Anthony Sherbondy, Gabriel N. Szabo
  • Treatment of infertility
    Patent number: 6585982
    Abstract: In vitro fertilization can be improved by adding a meiosis activating compound.
    Type: Grant
    Filed: March 20, 2000
    Date of Patent: July 1, 2003
    Assignee: NNA/S
    Inventors: Christian Grøndahl, Thomas Høst Hansen, Alexander Rübig, Christa Hegele-Hartung
  • Nutraceutical composition
    Patent number: 6585998
    Abstract: Provided is a nutraceutical composition including a tripeptoid component, a flavonoid component, guanidine hydrochloride, &agr;-lipoic acid, an amino acid component, a brazilin component, catalase, and, optionally, vitamin E ans selenium. The composition is effective to maintain normal blood sugar levels and normal levels of non-enzymatic protein glycosylation in a human.
    Type: Grant
    Filed: November 13, 2001
    Date of Patent: July 1, 2003
    Inventors: Rudolph Cartwright, Leo Edward Hendricks