Patents Examined by Blessing M. Fubara
  • Method for preparing a polymeric reagent
    Patent number: 9913913
    Abstract: A method for preparing a polymeric reagent is provided, which method includes the optional step of forming an N-hydroxysuccinimdyl ester derivative. Related methods, preparations, and so forth are also provided.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: March 13, 2018
    Assignee: Nektar Therapeutics
    Inventors: J. Milton Harris, Antoni Kozlowski, Samuel P. McManus, Michael D. Bentley, Stephen A. Charles
  • Topical antibiotic formulations
    Patent number: 9901541
    Abstract: There are disclosed topical silver(II) antibiotic formulations. Other embodiments are also disclosed.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: February 27, 2018
    Assignee: AIDANCE SKINCARE & TOPICAL SOLUTIONS LLC
    Inventors: Perry Antelman, Bharat Madhavan, Joshua Steven Stein, Elia Altabet, Shalom Lampert
  • Chemoembolisation
    Patent number: 9901590
    Abstract: A composition for chemoembolotherapy of solid tumors comprises particles of a water-insoluble water-swellable synthetic anionic polymer and, absorbed therein an anthracycline. Suitably the polymer is a poly(vinyl alcohol) based polymer and the drug is doxorubicin.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: February 27, 2018
    Assignee: BIOCOMPATIBLES UK LIMITED
    Inventors: Andrew Lennard Lewis, Peter William Stratford, Simon Leppard, Pedro Garcia, Brenda Hall, Maria Victoria Fajardo Gonzalez
  • Benzamide compounds and related methods of use
    Patent number: 9890117
    Abstract: Benzamide compounds and derivatives thereof, as can be used for selective inhibition of the SIRT2 enzyme and/or therapeutic use in the treatment of Huntington's disease.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: February 13, 2018
    Assignee: Northwestern University
    Inventors: Richard B. Silverman, Hua Wang, Mohammad Khanfar, Aleksey G. Kazantsev
  • Methods for treatment of bladder cancer
    Patent number: 9884028
    Abstract: Apparatus and methods for treatment of an internal cavity are provided. The internal cavity is coated with a treatment solution. The treatment solution can include a solidifiable matrix with or without a drug or combination of drugs incorporated therein, or a drug solution without a solidifiable matrix. The treatment solution is coated onto at least a portion of the internal cavity, and acts as a slow-release drug delivery system.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: February 6, 2018
    Assignee: UroGen Pharma Ltd.
    Inventors: Asher Holzer, Dorit Daniel, Eran Hirszowicz
  • Orally disintegrating tablet
    Patent number: 9861577
    Abstract: It is an object of the present invention to provide an orally disintegrating tablet that has desirable oral disintegrability and excellent tablet hardness, a process for producing the same, and the like. The present invention provides an orally disintegrating tablet comprising: at least one diluent selected from D-mannitol, lactose, trehalose, xylitol, maltitol, and erythritol; a drug; a disintegrant; and at least one binder selected form methacrylic acid copolymer S, methacrylic acid copolymer L, methacrylic acid-ethyl acrylate copolymer, ethyl acrylate-methyl methacrylate copolymer, and methyl methacrylate-butyl methacrylate-dimethylaminoethyl methacrylate copolymer.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: January 9, 2018
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Takafumi Sato, Motohiro Ota, Makoto Kigoshi, Hideki Morita
  • Anti-microbial foams containing polymer-stabilized silver nanoparticles
    Patent number: 9839715
    Abstract: An absorbent wound dressing comprises a hydrophilic porous substrate and polymer-stabilized silver nanoparticles distributed throughout the porous substrate. The silver nanoparticles have a particle size d50 in the range of about 45 nm to about 85 nm and the silver nanoparticles are present in the substrate in an amount of about 0.16% to about 1.5% by weight of the total weight of the substrate. The wound dressing produces a 7-day log reduction of 4 or more for bacteria in accordance with the Modified AATCC Test Method 100. The wound dressing is also non-cytotoxic in accordance with ISO 10993-5 standard procedure for medical device cytotoxicity assessment.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: December 12, 2017
    Assignee: Porex Technologies Corporation
    Inventors: Chandrasiri Jayakody, Anthony J. Joles, Ramesh Srinivasan, Geoffrey M. Stoltz
  • N-maleimidyl polymer derivatives
    Patent number: 9828465
    Abstract: The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a N-maleimidyl moiety without a linking group therebetween. The invention also provides two methods of preparing such linkerless N-maleimidyl polymer derivatives.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: November 28, 2017
    Assignee: Nektar Therapeutics
    Inventor: Xiaoming Shen
  • Fumagillol derivatives
    Patent number: 9827255
    Abstract: Disclosed are compounds of Formula 1, stereoisomers thereof and pharmaceutically acceptable salts of the compounds and stereoisomers, wherein R1 and R2 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating obesity and related diseases, disorders, and conditions associated with MetAP2.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: November 28, 2017
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Zacharia Cheruvallath, John David Lawson, Christopher McBride
  • Antiviral compositions
    Patent number: 9820939
    Abstract: The present invention provides a composition and an antiviral drug preparation, each comprising at least one water-insoluble antiviral drug and at least one water-soluble carrier material, wherein the water-insoluble antiviral drug is dispersed through the water-soluble carrier material in nano-disperse form. The present invention further provides processes for preparing the compositions and drug preparations, and also aqueous nano-dispersions obtained by combining water and the compositions.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: November 21, 2017
    Assignee: The University of Liverpool
    Inventors: Alison J. Foster, James Long, Steven P. Rannard, Dong Wang, David J. Duncalf, Andrew Owen
  • Dialysis precursor composition
    Patent number: 9821102
    Abstract: The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one calcium salt, and optionally potassium salt, and magnesium salt. According to the invention said glucose and said at least one calcium salt, are present as anhydrous components in said dialysis acid precursor composition.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: November 21, 2017
    Assignee: Gambro Lundia AB
    Inventors: Olof Jansson, Torbjorn Linden, Anders Wieslander
  • Tamper resistant dosage form comprising a matrix and melt-extruded particulates comprising a drug
    Patent number: 9814679
    Abstract: The present invention provides a dosage form, particularly a tamper resistant dosage form, comprising: melt-extruded particulates comprising a drug; and a matrix; wherein said melt-extruded particulates are present as a discontinuous phase in said matrix.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: November 14, 2017
    Assignee: EURO-CELTIQUE S.A.
    Inventor: Hassan Mohammad
  • Cosmetic composition comprising silica aerogel particles, a gemini surfactant and a solid fatty substance
    Patent number: 9795544
    Abstract: The subject of the present invention is a cosmetic composition of oil-in-water type comprising: (1) hydrophobic silica aerogel particles having a specific surface area per unit of mass (SM) ranging from 500 to 1500 m2/g and a size, expressed as volume-average diameter (D[0.5]), ranging from 1 to 1500 ?m ; (2) at least one gemini surfactant of formula (I): in which R1 and R3 denote, independently of one another, an alkyl radical containing from 1 to 25 carbon atoms; R2 denotes a spacer consisting of a linear or branched alkylene chain containing from 1 to 12 carbon atoms; X and Y denote, independently of one another, a —(C2H4O)a—(C3H6O)bZ group; n ranges from 1 to 10 ; and (3) at least one fatty phase comprising at least one fatty substance chosen from solid fatty substances and pasty fatty substances.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: October 24, 2017
    Assignee: L'Oreal
    Inventor: Raluca Lorant
  • Foamable otic pharmaceutical compositions
    Patent number: 9789106
    Abstract: The present invention relates a foamable otic pharmaceutical compositions comprising oil-in water emulsions which comprise an antibiotic agent and a propellant gas. The pharmaceutical compositions are administered to the ear as foam for treating ear disorders.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: October 17, 2017
    Assignee: OTIC PHARMA LTD.
    Inventors: Evgenia Lozinsky, Yanna Galibov, Rodrigo Yelin
  • Oral care compositions
    Patent number: 9782339
    Abstract: Described herein are oral care compositions comprising a crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide, together with particular co-polymers as additional excipients; including some embodiments which further comprise a calcium abrasive.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: October 10, 2017
    Assignee: Colgate-Palmolive Company
    Inventors: Suman Chopra, Dennis Ontumi, Prakasarao Mandadi, Venda Maloney
  • Hair bleaching or hair dye cosmetics
    Patent number: 9782332
    Abstract: Provided is a cosmetic product for hair bleaching or hair dyeing comprising a first agent comprising an alkali agent, a second agent comprising hydrogen peroxide, and a nonaerosol foamer container for discharging a mixed solution thereof in the form of foam, the mixed solution comprising the following components (A) to (C), (A) a anionic surfactant comprising sulfuric acid group, (B) anionic surfactant comprising carboxy group, and (C) a polymer comprising a diallyl quaternary ammonium salt as a constitutional unit and having a charge density of 5.5 meq/g or more and 8.0 meq/g or less.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: October 10, 2017
    Assignee: KAO CORPORATION
    Inventors: Toshio Ogawa, Yujiro Nakano, Shoichiro Kamitakahara, Yasuyuki Murase
  • Hair bleaching or hair dye cosmetics
    Patent number: 9782340
    Abstract: A cosmetic product for hair bleaching or hair dyeing comprises a first agent containing an alkali agent, a second agent containing hydrogen peroxide, and a nonaerosol foamer container for discharging a mixed solution thereof in the form of foam, the mixed solution containing 1 mass % or more of the components (A) and (B) in total, wherein a mass ratio (B)/(A) is 0.25 or more. (A) 0.01 to 5 mass % of an anionic surfactant containing sulfuric acid group represented by the following formula R—O—(CH2CH2O)n—[CH2CH(CH3)O]m—SO3M wherein R represents a C8-25 hydrocarbon group, n and m each represent an average number of moles added of 0 to 50, and M represents an alkali metal or NH4, and (B) a polymer comprising a diallyl quaternary ammonium salt as a constitutional unit and having a charge density of 5.5 meq/g or more and 8.0 meq/g or less.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: October 10, 2017
    Assignee: KOA CORPORATION
    Inventors: Toshio Ogawa, Yujiro Nakano, Shoichiro Kamitakahara, Yasuyuki Murase
  • Tamper resistant dosage forms
    Patent number: 9775812
    Abstract: The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: October 3, 2017
    Assignees: PURDUE PHARMA L.P., PURDUE PHARMACEUTICALS L.P.
    Inventors: William H. McKenna, Richard O. Mannion, Edward P. O'Donnell, Haiyong H. Huang
  • Tamper resistant dosage forms
    Patent number: 9775808
    Abstract: The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: October 3, 2017
    Assignees: PURDUE PHARMA L.P., PURDUE PHARMACEUTICALS L.P.
    Inventors: William H. McKenna, Richard O. Mannion, Edward P. O'Donnell, Haiyong H. Huang
  • Tamper resistant dosage forms
    Patent number: 9775811
    Abstract: The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: October 3, 2017
    Assignees: PURDUE PHARMA L.P., PURDUE PHARMACEUTICALS L.P.
    Inventors: William H. McKenna, Richard O. Mannion, Edward P. O'Donnell, Haiyong H. Huang