Abstract: A method includes receiving, from a primary pressure sensor, a pressure measurement indicative of a pressure of a patient cavity and controlling, by an insufflator, a supply of the insufflation fluid to the patient cavity based on the pressure measurement from the primary pressure sensor. The method further includes delivering, by a trocar, the supplied insufflation fluid to the patient cavity via an access port, wherein: the access port comprises a seal and a retractor; and the access port facilitates access therethrough to the patient cavity.

Abstract: A fluid delivery manifold system assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular manifold design consisting of separately constructed components cooperatively arranged and coupled to one another. The modular manifold construction allows for rapid manufacturing reconfigurations of one or more components with minimal costs to create new delivery manifold configurations that meet specific needs (i.e., different modes of delivery depending on agent to be delivered, such as subcutaneous, intramuscular, intradermal, intravenous injection, spray, or droplet delivery).

Abstract: Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes inserting an intramural crossing device into the vascular lumen, positioning at least the distal tip of the crossing device in the vascular wall, advancing an orienting device over the crossing device such that an orienting element of the orienting device resides in the vascular wall, inserting a reentry device, and re-entering the true vascular lumen.

Abstract: Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, fractional scar revision, and/or fractional tattoo removal are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, fractional scar revision, and/or fractional tattoo removal. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from the a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.

Abstract: The present disclosure describes a system for the delivery of therapeutic substances to the cavities of a patient. The system can include a wearable micropump that is fluidically coupled with a handpiece. The handpiece can be inserted, for example, into the middle ear via a surgical tympanotomy approach. The system can enable a controlled injection of a therapeutic substance directly into the patient's cavity.

Abstract: A bite block with inclined surfaces fits between a patient's upper and lower jaws to hold them apart and fixes the bite block position relative to the jaws. A support plate slides relative to the bite block to position a needle guide on the support plate along an axis of the support plate. A position stop on the support plate contacts the anterior border of the Ramus of the patient's mandible to position the needle guide along the axis. A syringe needle is guided by the needle guide to a predetermined location to administer anesthetic, preferably to the inferior alveolar nerve as it enters the mandible. The needle guide is inclined to avoid gaging and a tongue depressor attached to the support plate positions the patient's tongue.

Abstract: Intravesical drug delivery devices that include a device body, a number of solid drug tablets, and a retention frame. The device body includes a drug reservoir lumen and a retention frame lumen. The drug tablets is positioned in the drug reservoir lumen, and the retention frame is positioned in the retention frame lumen.

Abstract: Devices, methods, and kits for ocular drug delivery are described herein. An apparatus can include a housing, an energy storage member, a barrel, and a hub. The housing contains the energy storage member. A proximal end portion of the barrel is coupled to a distal end portion of the housing. The barrel is configured to contain medicament and includes at least a portion of a piston and an elastomeric member. The piston is configured to move the elastomeric member within the barrel in response to a force produced by the energy storage member. The hub is coupled to a distal end portion of the barrel. An inner surface of the hub defines a nozzle through which the medicament flows when the elastomeric member moves within the barrel. The nozzle and the energy storage member are collectively configured to produce a fluid jet to access a target location within an eye.

Abstract: Identification information for a patient and a user responsible for administering a medication are received from a controller associated with an infusion device. When a medication is scanned and information from the scan is received the system determines whether the user is authorized to operate the infusion device to administer the medication to the patient. If more than one order is available for the patient, pending medication orders for the patient are determined and presented on the controller for selection by the user before the administration. When a selected order is confirmed to be for the patient, and the user is authorized, the controller programs the infusion device to administer the medication according to the selected order.

Abstract: A prepackaged needleless intravenous line assembly is provided as well as a method of delivering intravenous medication and/or fluid to a patient while maintaining sterility of needleless access ports. The pre-packaged needleless intravenous line assembly is a sterile intravenous line with at least one sterile access port, each access port having a disinfection cap installed thereon, sealed within a pouch with at least one strip of multiple sealed disinfection caps. An intravenous tubing kit, having sterile intravenous tubing with capped sterile access ports as well as sealed replacement disinfection caps, is removed from the package and attached to a patient's intravenous catheter. A disinfection cap is removed from the sterile access port. Medication and/or fluid is administered into the access port. A replacement disinfection cap is installed onto the access port.

Abstract: An illustrated view of an exemplary emergency kit for use in an emergency medical condition and a method for automating the ordering of the emergency kits for dentist is presented. The emergency kit is useful for providing short-term medical relief in an emergency while waiting for ambulance or other emergency medical personnel to arrive at the scene. The emergency kit provides a useful medical syringe for use by a dentist in a mouth of a patient experiencing an emergency medical condition.

Abstract: The disclosure relates to a sensor system for detecting a position of a movable plunger in a drug delivery device, the sensor system comprising a sensor capable of detecting a magnetic field, the sensor adapted to be fixed within a housing of a drug delivery device, and a ferromagnetic or permanent magnetic component magnetically interacting with the sensor and adapted to move relative to the sensor as the plunger is moved.

Abstract: A medical device, comprising a hub or housing having a push tab including a main portion extending radially from an upper surface of the hub or housing, and at least one anti-rotation feature for resisting rotation of the hub or housing. A cannula is directly or indirectly connected to the hub or housing. The medical device may be a catheter, the cannula may be a catheter tube, and the hub or housing may be a catheter hub or an introducer needle tip shield for the catheter.

Abstract: A device for applying a tissue healing agent includes an insertion member extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, a delivery element including a first surface and a second surface opposing one another, the delivery element movable between a closed configuration, in which the delivery element is compressed to be received within the channel, and an open configuration, in which the delivery element is substantially planar, and a first tissue healing agent formed in a sheet configuration and disposed on the first surface of the delivery element.

Abstract: An IV adapter to allow for the mixing of multiple compatible medications with one another using a single bag of intravenous fluid. The IV adapter has multiple arms extending which gives rise to the ability to mix multiple medications. There is a spike within each arm to puncture the medication. The plurality of arms have built in mechanisms to control the flow of the medication and stop it from flowing in a certain direction. There are connections at the end of each arm allowing for a tight seal to be made to prevent any medication from leaking out of the IV line.

Abstract: A respiratory device comprising a housing enclosing a chamber and an orientation indicator moveable with respect to the housing between a first position indicative of an orientation of the housing predetermined to be suitable for operation of the respiratory device, and a second position indicative of an orientation of the respiratory device predetermined to be less suitable for operation of the respiratory device. The orientation indicator is positioned in a location on the respiratory device visible to a user during the operation of the respiratory device.

Abstract: A double barreled injector assembly for performing multiple sequential vaccinations includes a pair of barrels, each of which is engaged by a first terminus thereof to a bar and extends from a lower face thereof. A respective agent can be positioned in each barrel. Each barrel has an orifice positioned in a second terminus thereof. A pair of actuators is engaged to an upper face of the bar. Each actuator is operationally engaged to a respective barrel and can be actuated by action of a hand of a user to dispense an associated agent through the orifice of the respective barrel into an animal. The injector assembly allows the user to perform multiple sequential vaccinations with two different vaccines and will be useful in vaccination of herds or flocks of livestock, such as poultry, cattle, and the like.

Abstract: The present invention is directed to a method and apparatus for an electrotherapeutic system including a first and second electrode. Each electrode includes a respective resistance wherein during operation of the electrotherapeutic system, an electrochemical reaction involving one or both of the electrodes varies the respective resistance of at least one of the electrodes.

Abstract: Components for use in hollow organ irrigation systems are provided, including collapsible and expandable liquid reservoirs, self-supporting liquid containers for liquid reservoirs, and retaining elements for rectal catheters, which may be inflatable or un-inflatable.

Abstract: The present disclosure relates to methods, devices, kits and systems for enhancing the efficacy and longevity of denervation procedures.