Patents Examined by Brian E. Pellegrino
  • Patent number: 10792164
    Abstract: A spinal implant includes a hollow body having a distal end, a proximal end, and a pair of lateral walls extending from the distal end to the proximal end, the lateral walls having a concave-shaped cross-section and having concave, non-threaded interior surfaces for defining an at least partially cylindrical internal space between the lateral walls. The hollow body has upper and lower faces that are inclined relative to one another, whereby a distance between the upper and lower faces decreases from a first lateral side of the hollow body to a second lateral side of the hollow body opposite the first lateral side. The implant includes an anchoring member having bone anchoring projections that is inserted into the hollow body. The anchoring member is rotatable for enabling the anchoring member to be screwed into the internal space of the hollow body.
    Type: Grant
    Filed: November 16, 2004
    Date of Patent: October 6, 2020
    Assignee: Stryker European Operations Holdings LLC
    Inventor: Yves Crozet
  • Patent number: 10786372
    Abstract: An implantable frame comprises a plurality of corner structures configured to decrease pressure to the vessel wall and define pulsatility enhancing windows of the implantable frame. The corner structures may comprise plurality of neighboring longitudinal struts that extend in a longitudinal direction of the blood vessel when placed to form the vessel wall to a substantially polygonal cross-section and distribute pressure loading of the corner structure among the plurality of neighboring longitudinal struts to improve biocompatibility. The corner structures also allow increased forming of the vessel wall and can provide stretching of the vessel wall to enhance pulsatility of the vessel wall.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: September 29, 2020
    Assignee: Vascular Dynamics, Inc.
    Inventors: Chung Hao Yeh, Jennifer Gong, Brent Seybold, Christopher Ken, Suji Shetty, Edward F. Ruppel, Jr., Robert Stern
  • Patent number: 10772723
    Abstract: A prosthetic heart valve can include an expandable support stent, a valve assembly, and a connecting membrane. The support stent can have first and second end portions and can be configured to be radially expandable from a first configuration to a second configuration. The valve assembly can have an inlet portion, an outlet portion, and a plurality of leaflets, and the valve assembly can be supported in the support stent. The connecting membrane can be disposed radially between the support stent and the valve assembly, wherein the support stent and the valve assembly can be connected to the connecting membrane.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: September 15, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventor: Stanton J. Rowe
  • Patent number: 10744012
    Abstract: A stent includes a first section and a second section. The second section is aligned with the first section along a longitudinal axis of the stent. Each section includes a plurality of expandable modules and a plurality of bridging modules. Each expandable module includes a plurality of strut elements that join together at a plurality of apices. Each bridging module includes bridging elements that connect an apex of a first module with an apex of a second module. The plurality of expandable modules or the plurality of bridging modules in the first section are more radially stiff than the plurality of expandable modules or the plurality of bridging modules in the second section such that at least a portion of the first section is configured to be placed in a region of a vein subjected to physiologic compression.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: August 18, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Craig L. Bonsignore, Stephen J. Kleshinski, Andrea Seba Les
  • Patent number: 10709553
    Abstract: A replacement heart valve may include a tubular anchor member actuatable between an elongated delivery configuration and an expanded deployed configuration, a buckle member fixedly attached to the anchor member, a post member axially translatable relative to the buckle member, the post member including a latch portion configured to engage the buckle member when the anchor member is in the deployed configuration, an actuator member including a pivot pin proximate a distal end thereof, the actuator member being releasably connected to a proximal end of the post member at the pivot pin, and a valve leaflet attached to the post member. The post member may be disposed distal of the anchor member when the anchor member is in the elongated delivery configuration.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: July 14, 2020
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Andrew J. H. Backus, Ali Salahieh, Ning Pan, Stanley A. Carroll
  • Patent number: 10695169
    Abstract: An embodiment of the invention includes a sewing cuff for aortic heart valves that better approximates native anatomy by better mating with the crown-like anatomical annulus. Limiting distortion of the crown-like annulus provides better blood flow and overall valve function and provides a physician greater ease of implantation since native anatomy is not flattened. Thus, the surgeon may attach sutures to the fibrous tissue of the crown-like anatomical annulus without distorting the shape of the native anatomy. An embodiment includes a scalloped sewing cuff assembly (with semilunar arches) that tracks the crown-like annulus. Another embodiment provides a sewing cuff positioned over the majority of the valve's length, thus allowing the surgeon greater flexibility as to where he or she can attach sutures to the surgical annulus. Conventional valves, which are primarily “low-profile” devices, do not offer such ability. Other embodiments are described herein.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: June 30, 2020
    Assignee: On-X Life Technologies, Inc.
    Inventors: Francisco Javier Ruyra-Baliarda, Josep Gatell Ferre, Fletcher D. Southard, Jack Bokros, Elva Correa, Jeffery Poehlmann
  • Patent number: 10675149
    Abstract: A heart valve assembly includes a base including a multi-lobular annular shape within a plane, a valve member or other annular body including a multi-lobular shape complementary to the shape of the base, and cooperating connectors on the base and the annular body for connecting the annular body to the base. The base includes an anchoring ring, and a flexible cuff for attaching the base to a biological annulus. The base and the annular body include guides for aligning their multi-lobular shapes, e.g., visual, tactile, or other markers, or tethers that extend from the base that are slidable through the annular body. During use, the base is attached to a biological annulus, the annular body is directed adjacent the annulus, oriented such that the multi-lobular shape of the annular body valve member is aligned with the base, and the annular body is attached to the base.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: June 9, 2020
    Assignee: Medtronic, Inc.
    Inventors: Michael J. Drews, Donnell W. Gurskis, Stephen R. Bacich
  • Patent number: 10646333
    Abstract: A modular valve prosthesis includes an anchor stent and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the aorta and a proximal arm component extending from a proximal end of the tubular frame member and configured to be deployed in the sinuses of the aortic valve. The anchor stent further includes attachment members extending from an internal surface of the tubular frame member. The valve component includes a valve frame configured to be deployed within the tubular frame member of the anchor stent such that the valve frame engages with the attachment members of the tubular frame member and a prosthetic valve coupled to the valve frame.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: May 12, 2020
    Assignee: Medtronic, Inc.
    Inventor: Paul Rothstein
  • Patent number: 10610620
    Abstract: Devices and methods fabricating devices having nanostructures that allow adhesion or growth of one cell type, such as endothelial cells, more than another cell type, such as smooth muscle cells. In particular, stent covers may have nanostructures that allow adhesion or growth of one cell type more than another cell type. Nanostructures forming the devices may be optimized.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: April 7, 2020
    Assignee: Monarch Biosciences, Inc.
    Inventor: Alfred David Johnson
  • Patent number: 10610354
    Abstract: Apparatus and methods are described herein for anchoring a prosthetic heart valve. In some embodiments, an apparatus includes a tether attachment member that includes a base member that defines at least a portion of a tether passageway through which a portion of a tether extending from a prosthetic heart valve can be received therethrough. The base member defines a locking pin channel that intersects the tether passageway. A locking pin is disposable within the locking pin channel and movable between a first position in which the locking pin is at a spaced distance from the tether passageway, and a second position in which the locking pin intersects the tether passageway and can engage the portion of a tether disposed therein to secure the tether to the tether attachment member.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: April 7, 2020
    Assignee: Tendyne Holdings, Inc.
    Inventors: Robert M. Vidlund, Mark Christianson, Craig Ekvall
  • Patent number: 10603161
    Abstract: Apparatus and methods for nipple and breast formation are described where devices precondition or expand a target nipple tissue to reduce the pressure exerted by the skin on an eventual implant. Generally, the apparatus comprises a mold having a contact surface which is cured in conformance with a breast upon which the mold is positionable, the contact surface having an adhesive for securement upon the breast, and the mold defining a cavity along the contact surface which conforms to a size of a nipple to be formed upon the breast and where the cavity further comprises the adhesive for securement to the nipple. A breast enlargement device comprises a cup larger than the target breast and further defines an inner surface which adheres to the breast when contacted.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: March 31, 2020
    Assignee: TauTona Group Research and Development Company, L.L.C.
    Inventors: Kenneth N. Horne, Michael H. Rosenthal, Geoffrey C. Gurtner
  • Patent number: 10595981
    Abstract: The present technology relates generally to endovascular prostheses. More particularly, the disclosure relates to endovascular prostheses having a graft material and a stent structure attached with a suture, or a seam formed by a suture, where the suture has a coating that expands upon exposure to body fluids. The expansion allows for the coating to fill suture holes in the graft material so as to reduce or eliminate endoleaks.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: March 24, 2020
    Assignee: Medtronic Vascular, Inc.
    Inventors: Jeffrey Mitchell, Keith Perkins, Samuel Robaina, Rajesh Radhakrishnan
  • Patent number: 10583220
    Abstract: A biocompatible, bioresorbable tissue repair implant or scaffold device is provided for use in repairing a variety of cartilage tissue injuries, and particularly for resurfacing and/or repairing damaged or diseased cartilage. The repair procedures may be conducted with tissue repair implants that contain a biological component that assists in delaying or arresting the progression of degenerative joint diseases and in enhancing tissue healing or repair. The biocompatible, bioresorbable tissue repair implants include a scaffold and particles of viable tissue derived from cartilage tissue, such that the tissue and the scaffold become associated. The particles of living tissue contain one or more viable cells that can migrate from the tissue and populate the scaffold.
    Type: Grant
    Filed: August 11, 2003
    Date of Patent: March 10, 2020
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Francois Binette, Ed Yiling Lu
  • Patent number: 10555808
    Abstract: A prosthetic mitral valve includes an anchor assembly, an annular strut frame, and a plurality of replacement leaflets secured to the annular strut frame. The anchor assembly includes a ventricular anchor, an atrial anchor, and a central portion therebetween. The annular strut frame is disposed radially within the anchor assembly. An atrial end of the annular strut frame is attached to the anchor assembly such that a ventricular end of the annular strut frame is spaced away from the anchor assembly.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: February 11, 2020
    Assignee: Cephea Valve Technologies, Inc.
    Inventors: Dan Wallace, Spencer Noe, Peter Gregg, Juan F. Granada
  • Patent number: 10549138
    Abstract: An exoskeleton comprising a right hip attachment, a left hip attachment, a belt and a leaf-spring. The leaf-spring configured to couple two hips and apply torque from one respective hip to another respective hip based on the runner's movement and a right gear mechanism and a left gear mechanism, the right gear mechanism and the left gear mechanism comprising respectively of rack-and-pinion mechanism and configured to change an arch of the leaf-spring.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: February 4, 2020
    Inventors: Rezvan Nasiri, Majid Nili Ahmadabadi, Arjang Ahmadi
  • Patent number: 10524896
    Abstract: An implantable prosthesis is provided for reconstructing an anatomical feature, such as a breast nipple. The prosthesis may be formed from a biologic and/or synthetic material. The prosthesis may include a body with a shape that is suitable for reconstructing the anatomical feature. A base may be located at an end of the body to facilitate anchoring the prosthesis in position. The prosthesis may be provided with openings that allow fluid flow therethrough, tissue ingrowth, revascularization, neovascularization and/or fat or stem cell deposition. The prosthesis may include a plurality of layers of biocompatible material arranged in a stacked configuration. The layers may be in spaced relation relative to each other and secured or fixed in position to maintain the spacing therebetween. Each layer may have one or more openings extending therethrough. The spaced layer arrangement may provide a desired tactile response and/or natural movement for the prosthesis.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: January 7, 2020
    Assignee: C.R. Bard, Inc.
    Inventors: Karen E. Kullas, Tami L. Rathbun
  • Patent number: 10524904
    Abstract: Medical devices for positioning a valve in a subject's body, such as a prosthetic heart valve in a subject's heart, are disclosed. The prosthetic heart valve may include a valve assembly, a frame, and a control arm. The prosthetic heart valve may include a commissural post or multiple commissural posts. The prosthetic heart valve may include a positional marker on a control arm. The prosthetic heart valve may include multiple positional markers on one or more control arms. The positional markers can be shapes, characters, or other symbols. The positional markers may themselves be asymmetric. The positional markers may be placed in an asymmetric location on a control arm. The control arm may be asymmetrically shaped.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: January 7, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Barry O'Connell, Declan P. Costello, Michael A. Colson
  • Patent number: 10507098
    Abstract: A method of reproducing a biological object includes 3D-imaging the object and generating a mold using a 3D printer; obtaining cells from a donor site on the object; preparing a live cell suspension using the cells from the donor site; forming a scaffold in the mold with collagen and seeding the scaffold with live cells, growing the cells in the mold and curing the collagen; and surgically implanting the object into a living subject, where the cells continue to live in the living subject.
    Type: Grant
    Filed: April 7, 2018
    Date of Patent: December 17, 2019
    Inventor: Mariela Aguilar
  • Patent number: 10500049
    Abstract: A cord can be affixed to an annulus or adjacent tissue using anchors distributed about the cord to anchor respective regions of the cord to the annulus or adjacent tissue. Anchor launchers (which are supported by support arms) launch the anchors to embed them in the annulus or adjacent tissue. Flexible radio-opaque protrusions protrude distally beyond the anchor launchers. Progressive advancement of an anchor launcher in a distal direction beyond a point at which a protrusion makes contact with the annulus or adjacent tissue results in progressive deflection of the protrusion. This deflection can be visualized using fluoroscopy to ensure that the cord is positioned correctly before the anchors are launched. Some embodiments use an open loop of cord, in which case the cord can subsequently be used to constrict the annulus. Other embodiments use a closed loop of cord to prevent expansion of the annulus.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: December 10, 2019
    Assignee: Cardiac Implants LLC
    Inventor: David Alon
  • Patent number: 10500036
    Abstract: Method and apparatus for mapping the shape and dimensions of a 3-dimensional body, by applying to the 3-dimensional body a stretchable covering configured and dimensioned such that in its stretched condition it tightly engages and conforms to the shape and dimensions of the 3-dimensional body to be mapped. The stretchable covering carries a plurality of reference devices, such as bands and/or markers which are at know or determinable reference locations in an initial condition of the covering, and which change their locations in the stretched condition of the stretchable covering according to the shape and dimensions of the 3-dimensional body covered thereby. The locations of the markers on the stretchable covering are determined after the stretchable covering has been applied to the 3-dimensional body, and are utilized to produce a map of the shape and dimensions of the 3-dimensional body.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: December 10, 2019
    Assignee: DTherapeutics, LLC
    Inventor: Ghassan S. Kassab