Abstract: A trial acetabular cup having a signal generating device located thereon.

Abstract: Provided herein are bio-absorbable, settable and homogenous multi-putty bone-adhesive compositions for medical use in tissue hemostasis, surgical repair and reconstruction. Also provided are improved methods of intraoperative use of said compositions for re-approximation of adjacent bone fragments to create a restored alignment and stabilize fracture line.

Abstract: A stent-graft, including a generally tubular vascular graft of biocompatible material, and a plurality of bio-resorbable discrete annular members spaced apart along a longitudinal axis of the vascular graft and attached thereto.

Abstract: A method and system for making a preformed dental membrane using three-dimensional (3D) patient data. A patient jaw having insufficient bone at a surgical site may be scanned to provide a 3D image which may be used to design a virtual preformed dental membrane and fabricate for placement over packed bone graft substitute.

Abstract: A prosthetic heart valve can include a support stent, a valve assembly, and a connection structure. The support stent can have an inlet end portion and an outlet end portion, and can be configured to be radially expandable from a crimped configuration to an expanded configuration. The valve assembly can have an inlet, an outlet, and a plurality of leaflets. The connection structure supports the valve assembly in the support stent such that the inlet of the valve assembly is spaced radially inwardly of the support stent and forms an annular space between an inner surface of the support stent and the valve assembly at the inlet of the valve assembly when the support stent is in the expanded configuration. The annular space can have a width in a radial direction between 0.5 cm and 3 cm.

Abstract: Ameliorative actions are taken using a system equipped with sensors and equipment for attending to a patient. Operation of the system is controlled at a remote site or alternatively at the location of an injury. Injury assessment and the patient's affective and/or cognitive state may be facilitated through the analysis of data obtained by the sensors.

Abstract: Stent-grafts for treating thoracic aortic aneurysms and abdominal aortic aneurysms include graft portions having inflatable channels and graft extensions. The graft extensions include an undulating wire stent and porous, but substantially fluid impermeable, polytetrafluoroethylene (PTFE) graft materials.

Abstract: A stent for vascular interventions having a hybrid open cell geometry. Variants of the stent include bare metal stents and drug-eluting stents. Embodiments of the stent include end projections for radiopaque markers or a discontinuous partial radiopaque coating on low-stress or low-strain regions of the peripheral stent. The stents of the invention are characterized by having thin walls, nested rows of struts, high expansion ratio, high and uniform radial force over entire diametric size and length of device, crush resistance up to and including about 90% of its fully expanded diameter, high fatigue resistance and high corrosion resistance.

Abstract: An intravascular device configured to treat an aneurysm that includes a support structure including metal struts configured to be positioned in a body lumen and defining a central fluid passage that extends axially along the support structure, and a knitted mesh cover disposed over an exterior thereof and across a radial arc and along a length of the support structure sufficient to exceed an opening of an aneurysm to be treated, and the cover includes a polymer fiber having a diameter of at least 40 nanometers to 30 microns and apertures therethrough, the apertures being sized to prevent blood from passing through the device to prevent further expansion of the aneurysm. Devices including apertures that are at least 20 microns and sized to minimize or prevent an aneurysm-filling material from exiting the aneurysm through the knitted mesh cover and support structure, and methods of stenting, are also encompassed.

Abstract: Described embodiments are directed toward prosthetic heart valve leaflets of particular shapes that control bending character. In accordance with an embodiment, a prosthetic heart valve comprises a leaflet frame having a generally tubular shape with attached film. The leaflet frame defines a plurality of leaflet windows. The film defines at least one leaflet extending from each of the leaflet windows. Each leaflet attachment zone on the leaflet frame has substantially the shape of an isosceles trapezoid having two leaflet sides, a leaflet base and a leaflet free edge opposite the leaflet base. The two leaflet sides diverge from the leaflet base, wherein the leaflet base is substantially flat.

Abstract: Implantable grafts, particularly for arteriovenous access that may be punctured by an object such as a needle and, following removal of the object, will reseal the resulting hole to the extent of reducing fluid leakage through the graft at the puncture site to an amount less than would be typical for a conventional graft. More particularly, the grafts comprise three layers; an inner layer of implantable graft material such as ePTFE, a middle layer of self sealing elastomeric material such as silicone, and an outer layer of implantable graft material such as ePTFE. Following manufacture, the tubular form of the three-layer graft is everted to put substantially the entire wall thickness of the elastomeric material layer under circumferential compression.

Abstract: The present invention is an anatomic system which uses the principle of applying higher elastic tonus than the rest tonus of the agonist muscles to provide the function of the antagonist muscles, and which is designed in a simplest way to provide the said purpose and which can be integrated to the body. The static mechanism of the invention is an elastic mechanism which applies a continuous stable tension in order to keep the joints open. The tension of the mechanism is calibrated by increasing or decreasing the amount of the liquid in a chamber which has flexible and elastic walls up to a certain via a port. In the dynamic mechanism of the invention, the tension applied by the elastic mechanism can be changed according to the motion the patient wants to perform.

Abstract: A transapically-implanted mitral valve flexible closure plate blocking body comprising: a flexible closure plate (7), a left and right guide wire (8), a guide ring (13) and a fixation plug (12). The fixation plug (12) is fixedly implanted at a cardiac apex (4) of the heart, the flexible closure plate (7) is located at an anterior and posterior leaflet junction of the heart, the left and right guide wire (8) respectively pass through a hook (6) on the same side, are fixedly connected to the flexible closure plate (7) in the upper portion on the same side, and respectively pass through a guide ring (13) fixedly connected in the lower portion of the flexible closure plate (7) on the same side, and are fixedly connected to the fixation plug (12). An implantation method thereof is also provided.

Abstract: Systems and methods for remotely monitoring blood flow that include an endovascular prosthesis. The endovascular prosthesis includes a conduit forming a lumen within a surrounding wall having an inner surface and an outer surface. A monitoring device is disposed on the wall forming the lumen. The monitoring device comprises a sensor element configured to detect a physical event and to generate an electrical parameter shift in response to the physical event. An antenna portion is configured to receive a first oscillating electrical signal from an interrogator device and to transmit a second oscillating electrical signal to the interrogator device. The second oscillating electrical signal is modulated by the electrical parameter shift.

Abstract: An embodiment includes a chordal replacement system comprising: a pledget coupled to a first suture length and at least one of a first needle and a first ferrule; a second suture length coupled to the pledget and at least a second needle; and a third suture length coupled to the pledget and at least a third needle; wherein the second and third suture lengths are not monolithic with each other and do not constitute a single suture. Other embodiments are described herein.

Abstract: Described are implants for placing in a body, tools for delivering the implants, and systems and methods for using implants and tools for placing in a body and more particularly to nasal implants, tools for delivering nasal implants, and systems and methods for using such implants and tools. A tool may include a hand-held implant delivery device that holds, moves, orients, inserts, or shapes an implant. An implant may be a biodegradable, longitudinal implant that may be oriented for implantation by an implant delivery device.

Abstract: A medical device suitable for location in a body lumen is movable between a first loaded configuration and a second loaded configuration. The device has an unloaded configuration which is intermediate the first loaded configuration and the second loaded configuration. The device can be a stent for deployment in a blood vessel.

Abstract: An intravascular implant and methods of using the implant within the vasculature of the body, for example near a vascular aneurysm, are disclosed. A method of treating an aneurysm includes positioning a vascular graft comprising a tubular channel having a first end and a second end in a blood vessel, securing the vascular graft in place with an expandable anchoring member, and filling a seal cuff on the vascular graft, wherein the seal cuff extends radially outward beyond an exterior surface of the vascular graft, wherein the seal cuff comprises a first seal portion and a second seal portion and wherein the first seal portion is separated from the second seal portion by a first gap and a second gap along a circumference of the seal cuff.

Abstract: Described embodiments are directed toward prosthetic valves having a support structure and at least one leaflet. The leaflet comprises means for allowing fluid that is behind the leaflet to pass through to the front of the leaflet when the leaflet is not in the closed position. The prosthetic valve includes a leaflet moveable between an open position that permits antegrade flow through the prosthetic valve and a closed position that prevents regurgitant flow through the prosthetic valve, the leaflet having an aperture or gap, or a separation of portions of the leaflet to allow a flow or exchange of fluid between a front and back of the leaflet, when the leaflet is not in the closed position.

Abstract: An apparatus for replacing a diseased cardiac valve is movable from a radially collapsed configuration to a radially expanded configuration. The apparatus comprises an expandable support member and a prosthetic valve secured therein. The main body portion extends between first and second end portions and includes an outer circumferential surface, a circumferential axis extending about the circumferential surface, and a plurality of wing members spaced apart from one another by an expandable region. Each of the wing members includes first and second end portions and a flexible middle portion extending between the end portions. The second end portion is integrally formed with the uyimain body portion. The first end portion is adjacent the circumferential axis and substantially flush with the outer circumferential surface in the radially collapsed configuration. The first end portion extends substantially radial to the outer circumferential surface in the radially expanded configuration.