Abstract: A shear-thinning hydrogel composition includes: a first polymer chain including: (i) a first plurality of units each having at least one of a monosaccharide and an amino acid; and (ii) a cross-linking group bound to the at least one of the monosaccharide and the amino acid of one of the first plurality of units via conversion of a carboxyl group of the unit to a peptide bond; a second polymer chain including a second plurality of the units; and a cross-linking additive connecting one of the second plurality of units to the first polymer chain via the cross-linking group.
Type:
Grant
Filed:
July 12, 2019
Date of Patent:
February 4, 2020
Assignee:
OUROTECH, INC.
Inventors:
Duleeka Nimantha Bandara Ranatunga, Andrew Christopher Wenger, Zhi Yuan (William) Lin
Abstract: The invention relates to a hydrocarbon mixture that contains at least two hydrocarbons that are different from each other, the number of carbons thereof differing by more than one, wherein said two hydrocarbons that differ from each other make up at least 60% by weight, preferably at least 70% by weight of the total of the hydrocarbons. The invention also relates to the use of said hydrocarbon mixtures and to cosmetic and/or pharmaceutical preparations containing said hydrocarbon mixtures.
Type:
Grant
Filed:
October 18, 2016
Date of Patent:
January 21, 2020
Assignee:
Cognis IP Management GmbH
Inventors:
Markus Dierker, Bettina Jackwerth, Rolf Kawa, Stefanie Maurer
Abstract: Subject matter of the present disclosure is a conditioning shampoo containing (A) a mixture of the mono-, di- and tri-esters of a fatty acid mixture (F1) and glycerine, and (B) a mixture of the mono- and di-esters of a fatty acid mixture (F1) and a polyethylene glycol having a mean molecular mass of from 200 to 800 g/mol, wherein the fatty acid mixture (F1) is a mixture of fatty acids which has the same fatty acid composition as a plant-based oil, and, relative to the total weight of the shampoo, the total quantity of all the plant-based oils included in the shampoo, which are not the same as the tri-esters of the fatty acid mixture (F1) and glycerine, is a value of maximum 0.25 wt. %, and the total quantity of all the silicone compounds included in the shampoo is a value of maximum 0.25 wt. %.
Abstract: Provided herein are narrowly distributed multi-armed polyethylene glycol compounds, and hydrogels containing the same. Also provided are methods for treating, adhering, or sealing a biological tissue with hydrogels, and kits for making a hydrogel. Drug releasing compositions also are provided that include a narrowly distributed multi-armed polyethylene glycol compound.
Type:
Grant
Filed:
September 30, 2016
Date of Patent:
January 7, 2020
Assignees:
NOF Corporation, Massachusetts Institute of Technology
Abstract: Disclosed is a method for producing a porous monolithic material from at least one powder, preferably mineral, the method including at least one step of low-temperature compression of a mixture based on powder and at least one solvent, preferably water. The materials produced by the method have improved mechanical properties compared to the prior art materials. The materials for medical application, such as hydroxyapatite, also have improved biocompatibility compared to the prior art materials. Also disclosed are materials produced by the method.
Type:
Grant
Filed:
July 15, 2016
Date of Patent:
December 10, 2019
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQU, UNIVERSITE DE BORDEAUX
Abstract: Described herein are dental treatment compositions, more particularly, a dental varnish composition useful in effective fluoridation, enhancement of remineralization the tooth enamel, and hypersensitivity through occlusion of dentine tubule. The dental varnish composition includes a hydrogel system and at least one fluoride source, wherein the dental varnish is water soluble. The hydrogel system includes at least one polyphenol having at least one phenol group, at least one polymer, and a metal ion. Described herein are also methods of making such dental varnish composition.
Abstract: A nanocapsule includes a liquid hydrophobic care including an essential oil, and a shell encapsulating the core. The shell includes a copolymer having repeating units of Formula (I) and (II) wherein X, L1, R1, R2, y, and p are as described herein. A dispersion is also disclosed, wherein the dispersion includes a plurality of nanocapsules. The nanocapsules described herein are particularly useful for the treatment of bacterial biofilms.
Type:
Grant
Filed:
August 16, 2016
Date of Patent:
December 3, 2019
Assignee:
THE UNIVERSITY OF MASSACHUSETTS
Inventors:
Vincent M. Rotello, Ryan Francis Landis, Akash Gupta, Yiwei Lee
Abstract: A hemostatic putty for treatment of a variety of wounds topographies, including but not limited to highly three dimensional wounds, for example gunshot wounds and impalements, is disclosed. The putty is comprised of a matrix polymer weakly crosslinked or not crosslinked such that a viscoelastic matrix is formed. The viscoelastic nature of the putty is tunable by the composition and enables the putty to conform to a variety of wound topographies. Likewise, a hemostatic polymer, for example chitosan or hydrophobically modified chitosan, is included in this matrix to impart hemostatic properties and tissue adhesive on the putty. The hemostatic polymers disclosed prevent microbial infection and are suitable for oxygen transfer required during normal wound metabolism.
Type:
Grant
Filed:
February 27, 2017
Date of Patent:
December 3, 2019
Assignees:
GEL-E, Inc., University of Maryland, College Park, The General Hospital Corporation
Inventors:
Kevin Diehn, Matthew Dowling, Srinivasa R. Raghavan, David R. King
Abstract: A composition for treating a keratin material, comprising at least one amino acid surfactant, at least one amphoteric or zwitterionic surfactant, at least one solid fatty acid, at least one starch phosphates, and at least one acrylic thickening polymer. The composition has an improved rinsing speed after application, and is stable over 2 months, with an improved foaming properties, such as density of foam, and foaming volume.
Abstract: An oral care composition containing a stannous ion source, a zinc ion source, a polyphosphate, and a thickening agent. The thickening agent contains polyvinylpyrrolidone, a polysaccharide gum and carboxymethyl cellulose. The compositions have excellent rheology properties.
Type:
Grant
Filed:
January 14, 2019
Date of Patent:
November 26, 2019
Assignee:
Colgate-Palmolive Company
Inventors:
Kavita Vemishetti, Linh Fruge, Michael Prencipe
Abstract: The present invention provides compositions of a therapeutic agent and a polymeric stabilizing agent for stabilizing the reservoir of an implantable drug delivery system. The present invention also includes an implantable drug delivery system incorporating the composition of the present invention, as well as methods of treating diabetes using the compositions and implantable drug delivery system of the present invention.
Type:
Grant
Filed:
September 4, 2015
Date of Patent:
November 19, 2019
Assignee:
NANO PRECISION MEDICAL, INC.
Inventors:
Adam Mendelsohn, Au Duong, Kathleen Fischer, Wouter Roorda
Abstract: A composition for lubricant formulations is disclosed. The composition may include hypochlorite, dimethicone, and an emulsifier for improvement of lubricity. Methods of making and using the lubricant formulations are also disclosed.
Abstract: Embodiments of the invention are directed to a macromolecular chemotherapeutic. A non-limiting example of the macromolecular chemotherapeutic includes a block copolymer. The block copolymer can include a water-soluble block, a cationic block, and a linker, wherein the linker is connected to the water-soluble bock and the charged block.
Type:
Grant
Filed:
November 9, 2017
Date of Patent:
November 5, 2019
Assignees:
INTERNATIONAL BUSINESS MACHINES CORPORATION, AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventors:
Dylan Boday, Wei Cheng, Jeannette M. Garcia, James Hedrick, Nathaniel H. Park, Rudy J. Wojtecki, Chuan Yang, YiYan Yang
Abstract: The invention relates to a support consisting of natural and/or synthetic fibers which particles are held, which are preferably water-soluble, comprising at least one active agent, said particles at least partially releasing the active agent(s) under the effect of an external stress, characterized in the active agent has a water-solubility of between 0.1 and 60 wt. %, preferably between 0.1 and 30 wt. %.
Abstract: A controlled release system includes a polymeric support, wherein the polymeric support is biodegradable; a polymeric matrix, wherein the polymeric matrix includes polyhydroalkanoate; and encapsulated gases or volatiles; and a controlled release system includes a polymeric support; a polymeric matrix, wherein the polymeric matrix includes (poly-3-hydroxybutyrate-co-3-hydroxyvalerate) and poly (?-caprolactone); and encapsulated gases or volatiles.
Type:
Grant
Filed:
July 23, 2014
Date of Patent:
October 22, 2019
Assignee:
Universidad Andrés Bello
Inventors:
Luis Velásquez, Reinaldo Campos, Danilo Gonzalez, Rubén Polanco
Abstract: An acrylic fiber for artificial hair includes an acrylic polymer, wherein the acrylic polymer includes 29.5 to 79.5% by mass of acrylonitrile, 20 to 70% by mass of vinyl chloride and/or vinylidene chloride, and 0.5 to 5% by mass of a vinyl monomer comprising a sulfonic acid group. The acrylic fiber for artificial hair includes 0.3 to 2% by mass of a good solvent for the acrylic polymer and 0.1 to 5% by mass of a compound comprising an epoxy group.
Type:
Grant
Filed:
December 21, 2017
Date of Patent:
October 8, 2019
Assignee:
KANEKA CORPORATION
Inventors:
Takeshi Tanaka, Akihiro Okamoto, Tomomichi Hashimoto, Sota Okumura
Abstract: A sprayable sunscreen cosmetic contains substantially no ultraviolet ray scattering agents which cause whiteness, and which is transparent immediately after being applied/sprayed, and that has excellent ultraviolet ray protection effect and a good sensation in use. The ultraviolet ray protection effect is not reduced, and the effects improve when in contact with water. A water-in-oil emulsified sunscreen cosmetic comprises: (A) 6 to 40 mass % of an ultraviolet ray absorbing agent; (B) an organically modified clay mineral; (C) an oil phase thickener other than the aforementioned (B); (D) a silicone-based surfactant having an HLB of less than 8; (E) a spherical resin powder; and (F) a volatile silicone oil; wherein a ratio defined as [total amount of ingredient (B) and ingredient (C)]/[total amount of (G) non-volatile liquid oils other than silicone oils] is at least 0.04 and less than 0.68.
Abstract: Disclosed herein are foaming cosmetic compositions comprising: at least one anionic thickening agent; at least two alkaline compounds; and at least one silicone. Methods for producing the foaming cosmetic compositions and for improving the stability of a foamed cosmetic composition are also disclosed.
Abstract: A shear-thinning hydrogel composition includes: a first polymer chain including: (i) a first plurality of units each having at least one of a monosaccharide and an amino acid; and (ii) a cross-linking group bound to the at least one of the monosaccharide and the amino acid of one of the first plurality of units via conversion of a carboxyl group of the unit to a peptide bond; a second polymer chain including a second plurality of the units; and a cross-linking additive connecting one of the second plurality of units to the first polymer chain via the cross-linking group.
Type:
Grant
Filed:
June 29, 2017
Date of Patent:
September 17, 2019
Assignee:
OUROTECH, INC.
Inventors:
Duleeka Nimantha Bandara Ranatunga, Andrew Christopher Wenger, Zhi Yuan (William) Lin
Abstract: Multi-functional base emulsions that can be used to form a variety of cosmetic compositions are disclosed. In one aspect, a cosmetic emulsion can include a water phase including about 10% to about 67.5% water by total weight of the cosmetic emulsion. The cosmetic emulsion can also include an oil phase that includes (a) stearalkonium hectorite, and (b) a silicone alkyl polyether selected from the group consisting of: PEG/PPG-18/18 dimethicone, PEG/PPG-20/15 dimethicone, and Lauryl PEG/PPG-18/18 dimethicone.
Type:
Grant
Filed:
December 29, 2015
Date of Patent:
September 10, 2019
Assignee:
Kimberly-Clark Worldwide, Inc.
Inventors:
Stacy A. Mundschau, YoenJung Lee, Scott W. Wenzel, Jeffery R. Seidling