Abstract: Described herein are microelectrode array devices, and methods of fabrication, assembly and use of the same, to provide highly localized neural recording and/or neural stimulation to a neurological target. The device includes multiple microelectrode elements arranged protruding shafts. The protruding shafts are enclosed within an elongated probe shaft, and can be expanded from their enclosure. The microelectrode elements, and elongated probe shafts, are dimensioned in order to target small volumes of neurons located within the nervous system, such as in the deep brain region. Beneficially, the probe can be used to quickly identify the location of a neurological target, and remain implanted for long-term monitoring and/or stimulation.

Abstract: An apparatus and method for an electrocardiogram (ECG) cable suitable for use inside a Magnetic Resonance (MR) scanner during a Magnetic Resonance Imaging (MRI) operation. In particular, the present invention relates to a patient safe (MRI-conditional) 12-lead ECG cable capable of use inside an MR scanner during an MRI scan. The ECG cable does not heat up to a degree that would burn a patient undergoing an MRI scan, but also enables the conventional 12-lead ECG electrode placement required for diagnostic monitoring of the patient. Specifically, the ECG cable electrodes can be placed on a patient in the traditional configuration as 12-lead ECG cable designed for use outside of an MR scanner and take diagnostic level readings, during operation of an MR device or system. Additionally, the cable provides a continuous shield which maintains zero emissions while satisfying defibrillation requirements.

Abstract: A process for manufacturing an electrical lead having one or more electrodes includes providing an elongate member having at least one polymeric region and further having at least one electrical conductor that extends along at least a part of a length of the elongate member and that is contained in a wall of the elongate member. A length of the at least one electrical conductor is accessed at the at least one polymeric region. An electrically conductive adhesive is applied to the length of the at least one electrical conductor that has been accessed.

Abstract: A system for performing at least one impedance measurement on a biological subject, the system including a measuring device having a first housing including spaced pairs of foot drive and sense electrodes provided in electrical contact with feet of the subject in use, a second housing including spaced pairs of hand drive and sense electrodes provided in electrical contact with hands of the subject in use, at least one signal generator electrically connected to at least one of the drive electrodes to apply a drive signal to the subject, at least one sensor electrically connected to at least one of the sense electrodes to measure a response signal in the subject and a measuring device processor that at least in part controls the at least one signal generator, receives an indication of a measured response signal from the at least one sensor and generates measurement data indicative of at least one measured impedance value and a client device in communication with the measuring device, the client device being ada

Abstract: The present disclosure provides systems and methods for retrieving an implantable device. An implantable device includes a casing, and a marker coupled to the casing, wherein the marker includes a detectable material encased in a biocompatible material, and wherein the marker facilitates accurately locating and retrieving the implantable device after implantation in a patient.

Abstract: An electrophysiological laboratory system comprises a subsystem configured to perform diagnostic and/or therapeutic functions, a medical device, and an interface module disposed therebetween. The medical device comprises a shaft having proximal and distal portions, high- and low-impedance electrical pathways disposed within the shaft, and an electrode disposed at the distal portion of the shaft and electrically coupled to one or both of the high- and low-impedance electrical pathways. The electrode is configured to perform diagnostic and/or therapy delivery functions. The interface module comprises a high-impedance channel configured to couple the high-impedance pathway of the medical device to the subsystem, and to attenuate magnetic resonance RF and gradient field pulses generated by the MRI system. The interface module further comprises a low-impedance channel configured to couple the low-impedance pathway of the medical device to the subsystem.

Abstract: An ECG monitoring system includes two or more active electrodes, each active electrode having an electrode pad fixable to a patient to sense physiological potentials from the patient, a common connection port, and a wireless transmitter. The system further includes a common connector electrically connected to the common connector port of each of the two or more active electrodes to provide a comparator signal to each of the active electrodes. Each of the active electrodes compares the physiological potentials sensed at the electrode pad against the comparator signal to generate a cardiac signal, and then wirelessly transmits the cardiac signal with the wireless transmitter.

Abstract: A catheter comprises a flexible polymer catheter body including a proximal shaft section and a distal working section, a wire support structure embedded within the distal working section of the catheter body, a proximal adapter mounted to the proximal shaft section of the catheter body, and a wire disposed within the catheter body. The wire has a proximal end and a distal end. The proximal end of the wire being operably connected to the proximal adapter, and the distal end of the wire is anchored to the wire support structure.

Abstract: An electronic device comprising: a housing; a first structure extending outwardly from a surface of the housing; and a plurality of first electrodes disposed on the first structure and separated from each other by an insulating material.

Abstract: Example headsets and electrodes are described herein. Example electrode units described herein include a guide defining an opening and an electrode disposed in the opening. The electrode has a housing, a spring, and a pin. The pin is biased outward from a first end of the housing via the first spring. The example electrode units also include a second spring disposed over the opening adjacent a second end of the housing.

Abstract: The disclosure relates to a reduced Larsen Effect electrode. Specifically, the disclosure relates to an electrode with an insulation-coated electrode wire coaxially surrounded over a substantial portion thereof, by predetermined assembly of alternating rigid and isolating layers.

Abstract: The present invention relates to a physiological monitoring device. Some embodiments of the invention allow for long-term monitoring of physiological signals. Further embodiments may also allow for the monitoring of secondary signals such as motion.

Abstract: A method and system for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of mapping electrodes disposed in or near the anatomical structure, each of the plurality of mapping electrodes having an electrode location. A vector field map which represents a direction of propagation of the activation signals at each electrode location is generated to identify a signature pattern and a location in the vector field map according to at least one vector field template. A target location of the identified signature pattern is identified according to a corresponding electrode location.

Abstract: A sensor is disclosed comprising, in at least one embodiment an electrode, a track and an electrical connector, wherein, the track is comprising an electrically conductive flexible and elastic material that comprises an electrically conductive material that is non-contiguous that when stretched is able to transmit an electrical signal from an electrode to an electrical connector and from an electrical connector to an electrode.

Abstract: An intravascular catheter for nerve activity ablation and/or sensing includes one or more needles advanced through supported guide tubes (needle guiding elements) which expand to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the extra-luminal tissue including the media, adventitia and periadvential space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Electrodes at the distal ends of the guide tubes allow sensing of nerve activity before and after attempted renal denervation. In a combination embodiment ablative energy or fluid is delivered to ablate nerves outside of the media.

Abstract: Apparatus, having an insertion tube that is configured to be inserted into a body cavity. The apparatus also includes a distal tip connected to the insertion tube, the distal tip having an external surface and a cavity formed in the external surface, the cavity being surrounded by a region of the external surface having a curvature. The apparatus further includes a microelectrode configured to fit into the cavity so that a surface of the microelectrode is contoured, located and oriented to conform with the curvature of the region.

Abstract: Example headsets and electrodes are described herein. Example electrode units described herein include a housing having a cavity defined by an opening in a side of the housing and an electrode. In some such examples, the electrode includes a ring disposed in the opening and an arm, where the arm has a first portion extending outward from the opening away from the housing and a second portion extending from an end of the first portion toward the housing and into the cavity, and the first and second portions connect at a bend.

Abstract: An implantable optical electrode having a thin film electrode array including a plurality of electrodes, a light source associated with the thin film electrode array, and a passive bioactive agent delivery module associated with the thin film electrode array. Also disclosed are methods of manufacturing the array and a neural interface system with passive fluid delivery.

Abstract: A deployment control apparatus to control deployment of an array at an end of a catheter includes a pair of walls, a slider assembly, and a deployment shaft. The walls project from a first surface of the interior of a handle. The slider assembly includes a rigid body, an elastomeric element, a tab, and a knob. The elastomeric element is connected to the rigid body and at least partially disposed between the walls to frictionally engage with a surface of each wall. The knob is connected to the rigid body and is configured to maintain the elastomeric element between the walls. The deployment shaft connects the rigid body to the array, wherein a force applied to the knob sufficient to overcome the frictional engagement between the elastomeric element and the surface of each wall causes movement of the slider assembly and the deployment shaft to control deployment of the array.

Abstract: Physiological monitoring can be provided through a wearable monitor that includes two components, a flexible extended wear electrode patch and a removable reusable monitor recorder. The wearable monitor sits centrally (in the midline) on the patient's chest along the sternum oriented top-to-bottom. The placement of the wearable monitor in a location at the sternal midline (or immediately to either side of the sternum) benefits extended wear by removing the requirement that ECG electrodes be continually placed in the same spots on the skin throughout the monitoring period. Instead, the patient can place an electrode patch anywhere within the general region of the sternum. Power is provided through a battery provided on the electrode patch, which avoids having to open the monitor recorder's housing for battery replacement.