Abstract: An intraocular shunt can be manufactured using a system that includes a liquid bath and a wire, which is moved through the bath. When moved through the bath, the wire is coated with a material, such as gelatin. For example, the liquid bath can have a top layer, including water, and a bottom layer, including gelatin. The coated wire passes through an aperture formed in a plate component of the system. The gelatin can be dried on the wire in a humidity-controlled space, thereby forming the shunt.

Abstract: A method that relates to the fields of polymer chemistry, pharmacy and medicine and releases drugs as a component of implants into the environment of the implant. A method that, in a simple and easily reproducible manner, generates a drug delivery system, which releases drugs in a locally targeted and controllably delayed manner. Polyanions and polycations are mixed in a liquid in a non-stoichiometric ratio, relative to the charged monomer units, wherein drugs are added to the polyelectrolytes either before, during or after the mixing, or charge-carrying drugs and an oppositely charged polyelectrolyte are mixed, and after the mixing the polyelectrolyte complex produced is applied to the surface of a medical structure or material or is positioned on the surface directly at the location where the drug is to be released.

Abstract: A coating method and a coating apparatus are used to apply coating material to struts of a medical device (e.g., stent) which bound openings. The method involves optically scanning the medical device to produce position information identifying positions of the struts, using the position information to calculate a predetermined position, setting an applying manner to apply the coating material based on the predetermined position, setting an applying path accommodating the applying manner, and relatively moving the medical device and an applicator head along the applying route and path while dispensing the coating material from the applicator head and applying the coating material to the struts.

Abstract: A method for preparing a porous tantalum medical implant material, which includes (a) mixing a polyethylene glycol aqueous solution and tantalum powder to form a tantalum slurry, (b) casting the tantalum slurry into an organic foam body through vibrant pressurization, and (c) performing steps of drying, degreasing, vacuum sintering and thermal treatment to obtain the porous tantalum. The solution is a 2-8 wt % polyethylene glycol aqueous solution, the frequency of vibration is 20-80 times/min, the thermal treatment is performed under 10?4-10?3 Pa of vacuity and the temperature is first increased to 800-900° C. at a rate of 10-20° C./min and kept at 800-900° C. for 240-480 minutes, then is decreased to 400° C. at a rate of 2-5° C./min and kept at 400° C. for 120-300 minutes, and is cooled down to room temperature naturally in the furnace.

Abstract: Medical containers made of plastic can be protected against cracking by adding a layer of a poly-paraxylylene structure to said container.

Abstract: A method of loading a composition into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The structural element, or a stent having such a structural element, is immersed in a solution or a composition, and the composition or solution is allowed to fill the lumen. The composition or solution may comprise a therapeutic agent.

Abstract: A method for manufacturing a medical product comprising a hollow body (2), wherein at least part of a wall of the hollow body (2) is coated at least on the inside with a layer comprising a polymer; at least the part of at least the inside of the wall of the medical product is brought into contact with a mixture (6) of the polymer and the polymer is deposited from the mixture (6) on at least the part of the inside of the wall. And a medical product comprising a hollow body (2) with a wall consisting of one or more structural elements (16), at least a section of the wall being coated with a layer (15) comprising native chitosan, wherein both on the inside and the outside of the hollow body (2) at least some of the one or more structural elements (16) of the wall of the hollow body (2) are at least partly coated with the native chitosan layer (15). And a method for electrodepositing a polymer on an electrode from an acidic mixture of the polymer, wherein the mixture (6) comprises a multibasic acid.

Abstract: A medical implant comprises a biodegradable magnesium-based alloy of which at least a part of its surface layer comprises a magnesium carbonate. A method for the manufacture of a biocompatible, corrosion-inhibiting protective surface layer on a medical implant comprising a magnesium-based alloy, comprises: providing an implant comprising a magnesium-based alloy to be coated; placing the implant into a reactor chamber; exposing at least part of the surface of said implant to an atmosphere comprising humid carbon dioxide to produce a coating on the surface of the implant comprising a magnesium carbonate of the formula x MgCO3.y Mg (OH)2, whereby x+y=1; removing the implant from the reactor chamber; and drying the surface of the implant.

Abstract: A method of making a stent, including preparing a solution containing a composition, the composition comprising a biodegradable polymer and a vascular intimal hyperplasia inhibitor of a kind, including argatroban, which does not inhibit proliferation of endothelial cells, the weight compositional ratio of the polymer to the vascular intimal hyperplasia inhibitor being within the range of 8:2 to 3:7, the composition dissolved in a solvent selected from the group consisting of a mixture of a lower alkyl ketone and methanol, a mixture of a lower alkyl ester and methanol or a mixture of a lower halogenated hydrocarbon and methanol; coating at least an outer surface of a stent body of a cylindrical configuration having outer and inner surfaces with a diamond-like thin film coated on the surfaces; and after the coating, removing the solvent to complete a first coated layer.

Abstract: A method of manufacturing a fuser member is described. The method includes obtaining a substrate and coating a composition of an anhydride capped polyamic acid oligomer, a multi-amine and a solvent on the substrate to form a polyimide gel layer on the substrate. The solvent is extracted from the polyimide gel layer with an extraction solvent. The extraction solvent is removed to form a polyimide aerogel layer having a porosity of from about 50 percent to about 95 percent. A fluoropolymer is coated on the polyimide aerogel layer and cured or melted to form a release layer.

Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.

Abstract: Disclosed herein are methods of treating an article surface. The method comprises removing a metal oxide surface from the metal substrate to expose a metal surface; and delivering particles comprising a dopant from at least one fluid jet to the metal surface to impregnate the surface of the article with the dopant. The method also comprises delivering substantially simultaneously a first set of particles comprising a dopant and a second set of particles comprising an abrasive from at least one fluid jet to a surface of an article to impregnate the surface of the article with the dopant.

Abstract: The invention relates to a method for coating of a medical implant that can be used to apply a calcium salt to the surface of a medical implant easily and without expensive coating equipment and little expenditure of time. Accordingly, a method is provided that includes (i) providing a medical implant that includes at least one surface to be coated; (ii) providing a body that includes at least one calcium salt with a Mohs hardness of no more than 5.5 on at least one of its surfaces; and (iii) rubbing said body having the calcium salt-containing surface onto the at least one medical implant surface to be coated in order to coat said surface of the medical implant with the at least one calcium salt.

Abstract: A high-purity porous metal coating is formed over a substrate by thermal spraying a metal coating material over the desired portion of the substrate in an atmospheric air environment. The metal coating material may react with the atmosphere to cause impurities in the applied coating. The impurity-rich portion of the applied coating is subsequently removed to form the high-purity porous metal coating. Process steps are included that cause the impurity-rich portion of the applied coating to be a surface portion that is removable to arrive at the high-purity coating. A protective shroud may be used to limit the amount of impurity imparted to the applied coating and/or a getter material may be employed to continually bring impurities toward the surface of the coated substrate during coating.

Abstract: A shoe ornament structure, comprises: a base layer, a sub-base layer, a ground color layer, a ornamental layer, a blocking wall and a transparent layer. The ground color layer has a predetermined thickness and is formed on the sub-base layer. The ornamental layer is formed with different grains or color or materials and located on the ground color layer. The blocking wall of a height 0.5-0.7 mm is formed on ornamental layer, and the transparent layer is formed in the area defined by the blocking wall.

Abstract: The invention relates to a method for providing organic, semi-organic, mineral, inorganic and hybrid thin layers and thin layers containing nanoparticles, by simultaneous or alternate spraying of solutions of reactive partners (that is polymer/polymer interacting by hydrogen bonding, polyelectrolyte/small oligo-ion, inorganic compounds, etc.) on the surface of a solid substrate.

Abstract: The invention relates to an orthopedic cushion made from a filled elastomer or softened thermoplastics and can be provided with a thin friction-reducing coating made from a non-polar, non-hydrophilic slip-increasing polymer coating namely poly(para-xylene). According to the invention, the above can be achieved by means of a method in which the polymerized polyurethane cushion is subjected to at least one pretreatment step in which volatile components are removed to such an extent as to be able to be immediately coated.

Abstract: There is described a method for depositing at least one biological fluid onto a surface of a substrate, the method comprising the steps of (i) providing at least one thermal bubble jet printhead loaded with at least one biological fluid, (ii) positioning the printhead next to the substrate, and (iii) supplying the printhead with energy thereby depositing the biological fluid onto the surface. The printhead is supplied with an energy E such that E>1.6*Eth where Eth is the threshold energy of the printhead. There are also described an apparatus for depositing at least one biological fluid onto a surface of a substrate and a microarray obtained by carrying out the depositing method.

Abstract: A taste masked particulate pharmaceutical formulation include a core that comprises an active pharmaceutical ingredient; at least a partial nanoparticle material layer on the core that comprises a nanoparticle material with a median particle size not greater than 100 nm; a first polymer layer that is at least partially water soluble and a second polymer layer that is water insoluble. The active pharmaceutical ingredient is completely released in 30 minutes in the USP Dissolution Test. A process of making the particulate pharmaceutical formulation using sequential fluidized bed coating steps under controlled conditions is also described.

Abstract: Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed.