Abstract: A device may receive, from one or more electrodes, information identifying brain activity for a first time period. The device may predict, based on the information identifying the brain activity for the first time period, predicted brain activity for a second time period that is to occur after the first time period. The device may determine, based on the predicted brain activity for the second time period, a brain stimulus for the second time period, wherein the brain stimulus is associated with a frequency and a phase determined based on the predicted brain activity for the second time period. The device may cause the brain stimulus to be applied in accordance with the frequency and the phase during the second time period.

Abstract: Disclosed herein are techniques related to glucose estimation without continuous glucose monitoring. In some embodiments, the techniques may involve receiving input data associated with a user. The input data may comprise discrete blood glucose measurement data associated with the user, activity data associated with the user, contextual data associated with the user, or a combination thereof. The techniques may also involve using an estimation model and the input data associated with the user to generate one or more estimated blood glucose values associated with the user.

Abstract: A computer implemented method for determining heart arrhythmias based on cardiac activity that includes under control of one or more processors of an implantable medical device (IMD) configured with specific executable instructions to obtain far field cardiac activity (CA) signals at electrodes located remote from the heart, and obtain acceleration signatures, at an accelerometer of the IMD, indicative of heart sounds generated during the cardiac beats. The IMD is also configured with specific executable instructions to declare a candidate arrhythmia based on a characteristic of at least one R-R interval from the cardiac beats, and evaluate the acceleration signatures for ventricular events (VEs) to re-assess a presence or absence of at least one R-wave from the cardiac beats and based thereon confirming or denying the candidate arrhythmia.

Abstract: A nerve stimulator and a manufacturing method thereof. The nerve stimulator includes a glass substrate, and a plurality of metal pins provided on the substrate, wherein the metal pins form stimulation portions on one side of the substrate, and the density of the metal pins is greater than 15 Pin/mm2. The stimulation portions in the present nerve stimulator have a high density and a good stimulation effect. The processing method thereof is to cut out a high-density metal pin array first by using a metal underlayer, then the manufacturing method overcomes the deficiency in the prior art that it is rather difficult to manufacture a high density of nerve stimulation electrodes by using other substrates such as ceramics and the like.

Abstract: An illustrative proximity detection system directs a first electrode of an electrode lead to apply a first pulse and directs a second electrode of the electrode lead to apply a second pulse concurrently with the first pulse so as to form a dipole that generates a field. The first and second electrodes are each configured as stimulating electrodes that apply stimulation to the cochlear tissue when the electrode lead is located at a resting position subsequent to a surgical insertion of the electrode lead into a cochlea of a patient. After the pulses are applied, and based on an energy magnitude of the field that is detected to reflect from cochlear tissue located within the field, the proximity detection system determines a proximity of the electrode lead to the cochlear tissue. Corresponding systems and methods are also disclosed.

Abstract: An adaptive controller used in a photoplethysmography sensing system, comprises a plurality of hardware circuits which are configured to: receive a photoplethysmography signal (hereinafter, “PPG signal”) processed; determine whether the PPG signal processed satisfies with a requirement; output the PPG signal processed if the PPG signal processed satisfies with a requirement; and adjust a gain of an amplifier for amplifying the PPG signal and/or a driving signal of a light source if the PPG signal processed does not satisfy with a requirement.

Abstract: Wrist-wearable apparatuses that may be removed and used as a chest-applied cardiac device may include two chest electrodes on an inner surface of a strap (or strap regions), as well as two finger or more finger electrodes on the opposite side of the apparatus. The apparatus may be removed from the wrist and placed on a chest of a patient such that two electrodes are spaced at least five centimeters apart and in contact with the chest and held in place with two or more fingers to capture orthogonal cardiac signals that may be synthesized into a conventional 12-lead cardiac signal.

Abstract: A wearable medical monitoring (WMM) system may be worn for a long time. Some embodiments of WMM systems are wearable cardioverter defibrillator (WCD) systems. In such systems, ECG electrodes sense an ECG signal of the patient, and store it over the long-term. The stored ECG signal can be analyzed for helping long-term heart rate monitoring of the patient. The heart rate monitoring can be assisted a) by special filtering techniques that remove short-term variations inherent in patients' short-term heart rate determinations, and b) by indication techniques that indicate when conditions hampered sensing of the ECG signal too much for a reliable heart rate determination.

Abstract: The present invention is directed to a wearable fitness and/or heart rate monitoring device which includes motion detecting sensor(s), a galvanic skin response (GSR) sensor, a user input interface, or any combination thereof. The device accounts for signal noise, produced when an individual passes thru varying exercise states, by filtering out the motion of the individual using a 3-axis accelerometer. The invention also provides for systems and methods of operating the monitor which extracts and/or stores true or correct heart rate values from the heartbeat waveform signal observed from a PPG.

Abstract: Disclosed is a plasma generator. The plasma generator may include a gripping portion including at least one interface unit configured to receive an input from a user; a head portion including a plasma generating portion configured to generate the plasma; a first cartridge configured to detachably couple at a first end of the head portion and generate the plasma over a predetermined region; and a light irradiation portion provided at a second end of the head portion.

Abstract: A cardiac device comprises a memory arranged for receiving haemodynamic data, and a computer arranged for applying a cardiovascular model comprising a cardiac model and an arterial and venous blood circulation model using the data received in the memory, and for extracting therefrom at least one cardiac activity indicator (CI).

Abstract: A system and method for managing defibrillators and for coordinating their use during the SCA event to increase the probability of survival for the person experiencing sudden cardiac arrest. Defibrillator monitoring units and direction prompters are installed at registered geographical locations. A defibrillator monitoring unit closest to a cardiac arrest event is identified and a subset of the one or more client devices proximate event are sent an assistance request. One of the devices sends an accept message indicating acceptance of the request an activation message is sent to the subject client device to initiate transmission of active beacon signals by the device to activating at least one of the direction prompters so as to provide geographical direction to the identified defibrillator monitoring unit or audio/visual indicators associated with the identified defibrillator monitoring unit.

Abstract: A living body stimulator includes a low-frequency pulse generator, a high-frequency signal generator, a synthesizer for forming a synthesized waveform where a high-frequency signal of the high-frequency signal generator is superimposed on a low-frequency pulse signal of the low-frequency pulse generator, a waveform control signal circuit for controlling the synthesizer so that one cycle includes an ON period of the synthesized waveform where the high-frequency signal is superimposed on the low-frequency pulse signal and an OFF period where the high-frequency signal is not superimposed on the low-frequency pulse signal, and an output transformer for receiving the synthesized waveform. An impedance on an output side of the output transformer is set such that a voltage of the synthesized waveform gradually increases and decreases during the ON period on the output of the output transformer when pads connected to the output of the output transformer are attached to the living body.

Abstract: A balloon catheter device with a fluid management system includes a source of balloon fill media and a balloon catheter in fluid communication with the source of balloon fill media. A first conduit is provided for delivering the balloon fill media from the source to the balloon catheter for inflation of a balloon of the catheter device. A second conduit is provided for returning the balloon fill media from the balloon catheter to the source for deflating the balloon. A first pump is disposed along one of the first conduit and the second conduit for pumping the balloon fill media through the respective conduits.

Abstract: An electric current stimulation device includes a first electrode and a second electrode that are arranged in a body, and an output circuit that outputs an electric signal; wherein the electric signal by which the user feels no pain is output from the output circuit, and the electric signal is applied to a distal portion of extremities or near the same by the first electrode and the second electrode when arranging the body at the distal portion of the extremities of the user or near the same.

Abstract: Methods are provided for regulating tooth movement and for maintaining or improving tissue health using heavy forces. Such methods comprise allowing a heavy force to be exerted on one or more teeth of a patient in need thereon and administering an effective amount of light to the maxillary or mandibular alveolar bone of the patient, wherein the light is administered before, during, or after the heavy force is exerted. The light can have a wavelength in the range of about 585 nm to about 665 nm, or about 815 nm to about 895 nm. An apparatus useful for providing light therapy is also provided.

Abstract: A medical device system and method are disclosed for treating obstructive sleep apnea. The system includes a pulse generator and a medical electrical lead including multiple electrodes carried by a distal portion of an elongated lead body. The method includes advancing the distal portion within protrusor muscle tissue below the oral cavity and delivering electrical stimulation pulses via the electrodes to sustain a protruded state throughout a delivery time period to sustain a protruded state of a patient's tongue throughout the therapy delivery time period. The therapy delivery time period may span multiple respiration cycles.

Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neutral- and non-neural tissue of the nervous structure, inhibiting the perception of pain while preserving other sensory and motor function, and proprioception.

Abstract: An electrocardiogram (ECG) extension cable includes a first connector configured to be electrically coupled to a physiological monitoring device, a second connector configured to be electrically coupled to an ECG lead set including a processor, an input/output (I/O) wire configured to transmit data between the physiological monitoring device and the processor, a ground wire that establishes a ground path between the first connector and the second connector, a series protection element coupled in series along the ground wire, a bypass path coupled to the ground wire in parallel to the series protection element, and a switching element arranged along the bypass path and configured to redirect the ground path along the bypass path, thereby bypassing the series protection element.

Abstract: An external controller assembly for a medical device implanted in a patient includes an external controller and an external driveline assembly. The external controller includes an external controller display viewable by the patient. The external driveline assembly includes an external driveline cable and an external driveline distal connector. The external driveline cable is connected to the external driveline distal connector and the external controller. The external driveline cable accommodates positioning of the external driveline distal connector, by the patient, for simultaneous viewing of the external driveline distal connector and the external controller display by the patient. The external driveline distal connector is adapted to be connected to the distal driveline proximal connector by the patient. The external driveline distal connector is adapted to be disconnected from the distal driveline proximal connector by the patient.