Patents Examined by Casey Hagopian
  • Polymer particles prepared from polymerisable alkylene glycol (meth) acrylate monomers
    Patent number: 8940336
    Abstract: The invention provides polymer particles that are obtainable by a method selected from emulsion methods, diffusion methods and evaporation methods carried out in the presence of surface-engineering surfactant which is one or more polymer that displays a lower critical solution temperature, in aqueous media, that is between 10 to 90° C., this polymer being the polymerization product of one or more monomer selected from polymerisable alkyleneglycol acrylate monomers and polymerisable alkyleneglycol methacrylate monomers. The polymer particles can be used in controlled release applications, such as flavour release applications, fragrance release applications and biomedical applications. The invention also provides a cell support matrix comprising the polymer particles.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: January 27, 2015
    Assignee: University of Nottingham
    Inventors: Cameron Alexander, Kevin Shakesheff, Liang He, Martyn Davies, Wenxin Wang, Brian Saunders
  • Adjusting drug loading in polymeric materials
    Patent number: 8940799
    Abstract: Drug loading of polymeric materials can be adjusted by selection of materials and/or adjusting processing steps in formation of an implantable drug-loaded device.
    Type: Grant
    Filed: March 25, 2010
    Date of Patent: January 27, 2015
    Assignee: Medtronic Xomed, Inc.
    Inventors: William Jeffrey Bertrand, Patrick Marek, Drew Amery
  • Hydrocolloid carrier beads with inert filler material
    Patent number: 8932634
    Abstract: This invention discloses carrier beads comprising a hydrocolloid polymer comprising at least one inert filler material, wherein the at least one filler material provides improved properties including increased mechanical strength and/or reduced porosity relative to a bead without said at least one filler. The beads are useful per se or for delivery of active agents. Methods for preparation of the beads and the uses thereof are described particularly for controlling the rate of release an active agent from said bead.
    Type: Grant
    Filed: June 17, 2007
    Date of Patent: January 13, 2015
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd
    Inventors: Amos Nussinovich, Avi Gal
  • Medical imaging reference devices
    Patent number: 8920826
    Abstract: A medical device can be placed within or on the body of a patient. The device can include one or more imaging agents to allow visualization of the location of the device by an imaging system such as an MRI, an ultrasound, a PET, a CT, or an IR imaging system.
    Type: Grant
    Filed: January 6, 2006
    Date of Patent: December 30, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Weenna Bucay-Couto
  • Drug-impregnated encasement
    Patent number: 8900620
    Abstract: A drug-impregnated sleeve for encasing a medical implant is provided. In one embodiment, the sleeve may include a body made of a biologically-compatible material that defines an internal cavity configured to receive the medical implant. In one embodiment, the biologically-compatible material is bioresorbable. The body may include a plurality of apertures, such as perforations or holes, extending from the cavity through the body. The sleeve may further include a first end, a second end, and a drug impregnated into the resorbable sheet. In one possible embodiment, the first end of the sleeve may be open for receiving the medical implant therethrough and the second end may be closed. The implant may be encased in the sleeve and implanted into a patient from which the drug is dispensed in vivo over time to tissue surrounding the implantation site.
    Type: Grant
    Filed: October 12, 2006
    Date of Patent: December 2, 2014
    Assignee: DePuy Synthes Products, LLC
    Inventors: Mark Thomas Fulmer, David A. Armbruster, Robert Frigg, Elliott A. Gruskin, Sean Hamilton Kerr
  • Reducing formaldehyde emissions in formal-containing compositions
    Patent number: 8895043
    Abstract: Method for reducing the formaldehyde emission of a composition containing a formal by adding urea, urea derivatives, amino acids, guanidine or guanidine derivatives.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: November 25, 2014
    Assignee: Air Liquide Sante (International)
    Inventors: Wolfgang Beilfuss, Ralf Gradtke, Ingo Krull, Klaus Weber
  • Zero-order prolonged release coaxial implants
    Patent number: 8889174
    Abstract: A coaxial implant has been developed using biodegradable polymeric materials. The coaxial implant has a core containing drug, surrounded by a semi-permeable membrane that controls the rate of release of material from the core. The core containing the drug and the polymer membrane(s) can be the same or different polymer. The core acts as a reservoir of drug, which partitions from the core polymer to form a saturated solution of drug at the polymer membrane.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: November 18, 2014
    Assignee: Durect Corporation
    Inventors: John W. Gibson, Arthur J. Tipton, Richard Holl, Stacey Meador
  • Controlled release carvedilol formulation
    Patent number: 8883207
    Abstract: A controlled release carvedilol formulation for less frequent, preferably once daily administration is described. The controlled release formulation comprises a therapeutically effective amount of carvedilol or a pharmaceutically acceptable salt thereof, a matrix forming polymer, a solubility enhancer and a pharmaceutically acceptable carrier. In one embodiment, a controlled release formulation having a therapeutically effective amount of carvedilol is contained in two or more subunits having different release profiles. The controlled release formulation is usable in the treatment and/or prophylaxis of one or more conditions such as cardiovascular disorders.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: November 11, 2014
    Assignees: TSH Biopharm Corporation Ltd., Innopharmax, Inc.
    Inventors: Wei-Hua Hao, Tsung-Hsin Lin, Ta-Chien Lu
  • Granular material for dosage forms
    Patent number: 8877249
    Abstract: A dosage form for controlled release is produced from a composition comprising a granular material having a mean particle diameter of 150 to 350 micrometers and a compactibility resulting in a compact with a tensile strength of at least 1.7 MPa when the granular material is subjected to a compaction pressure of 266 MPa, at least 80 percent of the granular material being a water-soluble cellulose ether, water-soluble cellulose ester, an alkylene oxide homo- or copolymer, or a blend thereof; and an active ingredient.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: November 4, 2014
    Assignee: Dow Global Technologies LLC
    Inventors: Tim D. Cabelka, Akshay Bellare, Ka Chun A. Chan, Tina P. Dasbach, Kacee B. Ender, Karl V. Jacob, Robert E. Scheid, Jr.
  • Topical sanitizer and method of use with gloves
    Patent number: 8871233
    Abstract: Topical sanitizer includes avenanthramides, which is an active component of oats that is beneficial to the skin. The topical sanitizer is used preferably in conjunction with gloves that have an inner coating that includes avenanthramides. By using topical sanitizer that includes avenanthramides before and after wearing gloves, the skin of the person wearing the glove is more exposed to the beneficial avenanthramides all during the workday, not just when wearing gloves. The result is healthier, much softer and more comfortable skin on the hands.
    Type: Grant
    Filed: April 16, 2013
    Date of Patent: October 28, 2014
    Assignee: The Idea Folder LLC
    Inventors: Mark James Redmond, Joseph H. Neuser
  • Method for treating a periodontal disease
    Patent number: 8865198
    Abstract: Provided is a method for treating a periodontal disease affecting a periodontal pocket of a patient. The method includes inserting an oral delivery device into the periodontal pocket at a frequency of about once every 4 days to about once every 6 weeks. The oral delivery device is a controlled release solid unit dosage form suitable for insertion into a periodontal pocket of a patient, including a therapeutically effective amount of at least one anti-inflammatory agent, at least one antibacterial agent, or the combination of at least one anti-inflammatory agent and at least one antibacterial agent.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: October 21, 2014
    Assignee: Dexcel Pharma Technologies Ltd.
    Inventors: Avi Avramoff, Eyal Shoshani, Adel Penhasi, Dan Oren
  • Coatings for implantable devices having a chromium oxide layer and a method of forming the same
    Patent number: 8858975
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: October 14, 2014
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • Drug-containing bioabsorbable fibers and implants
    Patent number: 8834915
    Abstract: Methods for producing drug-containing bioabsorbable fibers. Also disclosed are methods for treating diseases using a bioabsorbable drug delivery device.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: September 16, 2014
    Assignee: Manli International Ltd.
    Inventors: Shih-Horng Su, Ting-Bin Yu, Minh Nguyen
  • Flow manipulation in biological flows using vortex generators
    Patent number: 8834911
    Abstract: A device for use in combination with a fluid flow having a biologic component and subject to an adverse response to shear stress includes a surface in contact with the flow of the fluid. The surface has a longitudinal direction extending from a leading end toward a trailing end and aligned with a direction of the flow. The surface is susceptible to inducing boundary layer formation within the flow sufficient for a resulting shear stress to induce the response. The surface includes a surface feature sufficient to induce boundary layer tripping in the flow to retard growth of boundary layer formation along the length.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: September 16, 2014
    Assignee: Georgia Tech Research Corporation
    Inventors: Ari Glezer, Ajit P. Yoganathan, Lakshmi Prasad Dasi
  • Method for encapsulation of orally ingested materials to alter the site of digestion, site of action, or stability
    Patent number: 8828421
    Abstract: Comestible materials encapsulated by a film-forming composition including a plant protein source and methods of forming the same are provided. The film-forming composition affects the site of digestion of the comestible material within the digestive tract of an animal or a human thereby allowing the material to be most effectively utilized by the body. Also, the film-forming compositions may be used to enhance the stability of the encapsulated material and prevent undesired interaction with other components of a mixture.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: September 9, 2014
    Assignee: Kansas State University Research Foundation
    Inventors: James S. Drouillard, Thomas J. Herald, Matthew Greenquist
  • Sunscreen comprising a curcuma extract
    Patent number: 8815220
    Abstract: Sunscreen compositions containing an extract of Curcuma longa L. are provided, the sunscreens having an absorption that spans the UVA and UVB ranges in a manner that meets updated FDA recommendations without requiring the addition of titanium dioxide. The sunscreens can also include an extraction solvent that is at least substantially non-toxic and useful also as a pharmaceutically acceptable carrier in liquid dosage forms. Microemulsions and nanoemulsions are also provided to enhance the bioavailability and stability of the extracts in the sunscreens.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: August 26, 2014
    Assignee: California Northstate College of Pharmacy, LLC
    Inventors: Indiran Pather, Tibebe Zewdie Woldemariam
  • Preparation of shaped metal particles and their uses
    Patent number: 8802151
    Abstract: The instant invention relates to shaped transition metal particles, in particular in the form of a dispersion in an aqueous and/or organic medium, the manufacture thereof and their use as an infrared (IR) absorbing agent, an IR curing agent for coatings, an additive in conductive formulations, an antimicrobial agent or for sensoring organic and/or inorganic compounds. Further, the invention relates to dispersions comprising said shaped particles and an aqueous and/or organic medium, such as a thermoplastic or crosslinkable polymer, as well as to antimicrobial compositions and products.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: August 12, 2014
    Assignee: BASF SE
    Inventors: Nikolay A. Grigorenko, Michael Muehlebach, Florian Muehlebach
  • Non-weighing hair preparations
    Patent number: 8802068
    Abstract: An agent for treating keratin-comprising fibers, in particular human hair, which includes in a cosmetic carrier at least one cyclic siloxane, at least one C8 to C30 alkyl PEG/PPG dimethicone, and at least one cationic protein hydrolysate.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: August 12, 2014
    Assignee: Henkel AG & Co. KGaA
    Inventors: Thorsten Knappe, Bernd Richters, Helga van Flodrop
  • Medical devices having fluorine-containing polymer coatings with improved adhesion
    Patent number: 8795704
    Abstract: According to an aspect of the present invention, medical devices are provided which include a metallic substrate and a polymeric region disposed over and in contact with the metallic substrate. The polymeric region includes (a) a fluorine-containing polymer that contains at least one type of fluorine-containing monomer selected from a vinylidene fluoride monomer, a hexafluoropropylene monomer, and a combination thereof, and (b) an adhesion promoting copolymer that contains (i) at least one type of first monomer that covalently or non-covalently bonds with the metallic substrate and (ii) at least one type of second monomer selected from acrylate monomers, methacrylate monomers, fluorine-containing monomers, and combinations thereof.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: August 5, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Steve Kangas
  • Iron fortified food product and additive
    Patent number: 8795739
    Abstract: The present invention relates to a food product which has been fortified in iron content, comprising a Fe3O4 sphere. The present invention also relates to an iron-containing additive for use in the above food product, in the form of a Fe3O4 sphere. The present invention further relates to a method for preparing the above food product, comprising the steps of adding or mixing the iron-containing additive in solid or dispersed form with the food product, wherein the iron-containing additive is in the form of a Fe3O4 sphere.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: August 5, 2014
    Assignee: Magqu Co. Ltd.
    Inventors: Shieh-Yueh Yang, Che-Chuan Yang